2-Methoxystypandrone ameliorates brain function through preserving BBB integrity and promoting neurogenesis in mice with acute ischemic stroke

Biochemical Pharmacology

Volumn 87, Issue 3, 2014, Pages 502-514

  Chern, Chang Ming ^d   Wang, Yea Hwey ^e   Liou, Kuo Tong ^f   Hou, Yu Chang ^g,h   Chen, Chien Chih ^c   Shen, Yuh Chiang ^a,b,e  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c HUNGKUANG UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e NATIONAL TAIPEI UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Taiwan)

^f CHINESE CULTURE UNIVERSITY   (Taiwan)

^g TAO YUAN GENERAL HOSPITAL   (Taiwan)

^h CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Catenin; 2 Methoxystypandrone (2MS); doublecortin; Glycogen synthase kinase 3 (GSK3); Ischemic stroke; Subgranular zone (SGZ)

Indexed keywords

2 METHOXYSTYPANDRONE; ADAM PROTEIN; ADAM11 PROTEIN; ADAMTS20 PROTEIN; ALTEPLASE; BETA ACTIN; BETA CATENIN; CD11B ANTIGEN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NAPHTHOQUINONE; NEUROPROTECTIVE AGENT; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN FUNCTION; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN SLICE; CELL INFILTRATION; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFECT; INFLAMMATORY CELL; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROIMAGING; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBVENTRICULAR ZONE; SURVIVAL RATE; UPREGULATION; WESTERN BLOTTING;

2-METHOXYSTYPANDRONE; 2-METHOXYSTYPANDRONE (2MS); 2-MS; B-CELL LYMPHOMA 2; BBB; BCL-2; BLOOD-BRAIN BARRIER; COX-2; CYCLOOXYGENASE-2; DCX; DOUBLECORTIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 (GSK3); GSK3; I/R; INDUCIBLE NITRIC OXIDE SYNTHASE; INOS; ISCHEMIA REPERFUSION; ISCHEMIC STROKE; MCAO; MIDDLE CEREBRAL ARTERY OCCLUSION/REPERFUSION; NF-ΚB; NUCLEAR FACTOR-KAPPA B; SGZ; SUBGRANULAR ZONE; SUBGRANULAR ZONE (SGZ); SUBVENTRICULAR ZONE; SVZ; Β-CATENIN;

ANIMALS; ANTIGENS, CD11B; BLOOD-BRAIN BARRIER; BRAIN; BRAIN ISCHEMIA; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; IMMUNOLOGIC FACTORS; LEUKOCYTES; MALE; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; NAPHTHOQUINONES; NEUROGENESIS; NITRIC OXIDE SYNTHASE TYPE II; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STROKE; TRANSCRIPTION FACTOR RELA;

EID: 84892917418     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.11.018     Document Type: Article

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