-
1
-
-
84865113809
-
New cellular and molecular mechanisms oflung injury and fibrosis in idiopathic pulmonary fibrosis
-
Fernandez IE, Eickelberg O. New cellular and molecular mechanisms oflung injury and fibrosis in idiopathic pulmonary fibrosis. Lancet2012;380:680-688.
-
(2012)
Lancet
, vol.380
, pp. 680-688
-
-
Fernandez, I.E.1
Eickelberg, O.2
-
4
-
-
79951844263
-
Clinical course and prediction of survival inidiopathic pulmonary fibrosis
-
Ley B, Collard HR, King TE. Clinical course and prediction of survival inidiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011;183:431-440.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 431-440
-
-
Ley, B.1
Collard, H.R.2
King, T.E.3
-
5
-
-
82755161052
-
Idiopathic pulmonary fibrosis
-
King TE, Pardo A, Selman M. Idiopathic pulmonary fibrosis. Lancet2011;378:1949-1961.
-
(2011)
Lancet
, vol.378
, pp. 1949-1961
-
-
King, T.E.1
Pardo, A.2
Selman, M.3
-
6
-
-
0024307964
-
Collagen synthesis by normal andfibrotic human lung fibroblasts and the effect of transforming growthfactor-beta
-
Raghu G, Masta S, Meyers D, et al. Collagen synthesis by normal andfibrotic human lung fibroblasts and the effect of transforming growthfactor-beta. Am Rev Respir Dis 1989;140:95-100.
-
(1989)
Am Rev Respir Dis
, vol.140
, pp. 95-100
-
-
Raghu, G.1
Masta, S.2
Meyers, D.3
-
7
-
-
17844384822
-
Induction of epithelialmesenchymaltransition in alveolar epithelial cells by transforminggrowth factor-beta1: Potential role in idiopathic pulmonary fibrosis
-
Willis BC, Liebler JM, Luby-Phelps K, et al. Induction of epithelialmesenchymaltransition in alveolar epithelial cells by transforminggrowth factor-beta1: Potential role in idiopathic pulmonary fibrosis.Am J Pathol 2005;166:1321-1332.
-
(2005)
Am J Pathol
, vol.166
, pp. 1321-1332
-
-
Willis, B.C.1
Liebler, J.M.2
Luby-Phelps, K.3
-
8
-
-
79951805332
-
Epithelial-mesenchymal interactions in pulmonaryfibrosis
-
Chapman HA. Epithelial-mesenchymal interactions in pulmonaryfibrosis. Annu Rev Physiol 2011;73:413-435.
-
(2011)
Annu Rev Physiol
, vol.73
, pp. 413-435
-
-
Chapman, H.A.1
-
9
-
-
84856133737
-
Mechanical stress induceslung fibrosis by epithelial-mesenchymal transition
-
Cabrera-Beńtez NE, Parotto M, Post M, et al. Mechanical stress induceslung fibrosis by epithelial-mesenchymal transition. Crit Care Med 2012;40:510-517.
-
(2012)
Crit Care Med
, vol.40
, pp. 510-517
-
-
Cabrera-Beńtez, N.E.1
Parotto, M.2
Post, M.3
-
10
-
-
0035984567
-
Differences in the fibrogenicresponse after transfer of active transforming growth factor-beta1gene to lungs of fibrosis-prone" and "fibrosis-resistant" mousestrains
-
Kolb M, Bonniaud P, Galt T, et al. Differences in the fibrogenicresponse after transfer of active transforming growth factor-beta1gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mousestrains. Am J Respir Cell Mol Biol 2002;27:141-150.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 141-150
-
-
Kolb, M.1
Bonniaud, P.2
Galt, T.3
-
11
-
-
27544486641
-
Natural killer T (NKT) cells attenuatebleomycin-induced pulmonary fibrosis by producing interferongamma
-
Kim JH, Kim HY, Kim S, et al. Natural killer T (NKT) cells attenuatebleomycin-induced pulmonary fibrosis by producing interferongamma.Am J Pathol 2005;167:1231-1241.
-
(2005)
Am J Pathol
, vol.167
, pp. 1231-1241
-
-
Kim, J.H.1
Kim, H.Y.2
Kim, S.3
-
12
-
-
0142219897
-
The role of gp130/IL-6cytokines in the development of pulmonary fibrosis: Criticaldeterminants of disease susceptibility and progression?
-
Knight DA, Ernst M, Anderson GP, et al. The role of gp130/IL-6cytokines in the development of pulmonary fibrosis: Criticaldeterminants of disease susceptibility and progression? PharmacolTher 2003;99:327-338.
-
(2003)
PharmacolTher
, vol.99
, pp. 327-338
-
-
Knight, D.A.1
Ernst, M.2
Anderson, G.P.3
-
13
-
-
79251535322
-
A mouse model of airway disease:oncostatin M-induced pulmonary eosinophilia, goblet cell hyperplasia, andairway hyperresponsiveness are STAT6 dependent, and interstitialpulmonary fibrosis is STAT6 independent
-
Fritz DK, Kerr C, Fattouh R, et al. A mouse model of airway disease:oncostatin M-induced pulmonary eosinophilia, goblet cell hyperplasia, andairway hyperresponsiveness are STAT6 dependent, and interstitialpulmonary fibrosis is STAT6 independent. J Immunol 2011;186:1107-1118.
-
(2011)
J Immunol
, vol.186
, pp. 1107-1118
-
-
Fritz, D.K.1
Kerr, C.2
Fattouh, R.3
-
14
-
-
58149198189
-
Mechanisms ofoncostatin M-induced pulmonary inflammation and fibrosis
-
Mozaffarian A, Brewer AW, Trueblood ES, et al. Mechanisms ofoncostatin M-induced pulmonary inflammation and fibrosis.J Immunol 2008;181:7243-7253.
-
(2008)
J Immunol
, vol.181
, pp. 7243-7253
-
-
Mozaffarian, A.1
Brewer, A.W.2
Trueblood, E.S.3
-
15
-
-
0035987792
-
Oncostatin M stimulatesproliferation induces collagen production and inhibits apoptosis ofhuman lung fibroblasts
-
Scaffidi AK, Mutsaers SE, Moodley YP, et al. Oncostatin M stimulatesproliferation, induces collagen production and inhibits apoptosis ofhuman lung fibroblasts. Br J Pharmacol 2002;136:793-801.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 793-801
-
-
Scaffidi, A.K.1
Mutsaers, S.E.2
Moodley, Y.P.3
-
16
-
-
84890043130
-
Endothelial cells recruitmacrophages and contribute to a fibrotic milieu in Bleomycin lunginjury
-
Leach HG, Chrobak I, Han R, et al. Endothelial cells recruitmacrophages and contribute to a fibrotic milieu in Bleomycin lunginjury. Am J Respir Cell Mol Biol 2013;49:1093-1101.
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 1093-1101
-
-
Leach, H.G.1
Chrobak, I.2
Han, R.3
-
17
-
-
0035694910
-
Smad regulation in TGFbetasignal transduction
-
Moustakas A, Souchelnytskyi S, Heldin CH. Smad regulation in TGFbetasignal transduction. J Cell Sci 2001;114(Pt 24):4359-4369.
-
(2001)
J Cell Sci
, vol.114
, Issue.PART. 24
, pp. 4359-4369
-
-
Moustakas, A.1
Souchelnytskyi, S.2
Heldin, C.H.3
-
18
-
-
1842507279
-
Intracellular proteins and mechanismsinvolved in the control of gp130/JAK/STAT cytokine signaling
-
Carbia-Nagashima A, Arzt E. Intracellular proteins and mechanismsinvolved in the control of gp130/JAK/STAT cytokine signaling. IUBMBLife 2004;56:83-88.
-
(2004)
IUBMBLife
, vol.56
, pp. 83-88
-
-
Carbia-Nagashima, A.1
Arzt, E.2
-
19
-
-
84855702837
-
Glycoprotein 130 cytokine signal as atherapeutic target against cardiovascular diseases
-
Fujio Y, Maeda M, Mohri T, et al. Glycoprotein 130 cytokine signal as atherapeutic target against cardiovascular diseases. J Pharmacol Sci2011;117:213-222.
-
(2011)
J Pharmacol Sci
, vol.117
, pp. 213-222
-
-
Fujio, Y.1
Maeda, M.2
Mohri, T.3
-
20
-
-
84865708953
-
Genetic partitioning ofinterleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis
-
O'Donoghue RJJ, Knight DA, Richards CD, et al. Genetic partitioning ofinterleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis. EMBO Mol Med 2012;4:939-951.
-
(2012)
EMBO Mol Med
, vol.4
, pp. 939-951
-
-
O'Donoghue, R.J.J.1
Knight, D.A.2
Richards, C.D.3
-
22
-
-
84878992041
-
Bone morphogenetic protein-7 inhibitssilica-induced pulmonary fibrosis in rats
-
Yang G, Zhu Z, Wang Y, et al. Bone morphogenetic protein-7 inhibitssilica-induced pulmonary fibrosis in rats. Toxicol Lett 2013;220:103-108.
-
(2013)
Toxicol Lett
, vol.220
, pp. 103-108
-
-
Yang, G.1
Zhu, Z.2
Wang, Y.3
-
23
-
-
84878245379
-
Bone morphogeneticprotein-inducer tilorone identified by high-throughput screening isantifibrotic in vivo
-
Leppäranta O, Tikkanen JM, Bespalov MM, et al. Bone morphogeneticprotein-inducer tilorone identified by high-throughput screening isantifibrotic in vivo. Am J Respir Cell Mol Biol 2013;48:448-455.
-
(2013)
Am J Respir Cell Mol Biol
, vol.48
, pp. 448-455
-
-
Leppäranta, O.1
Tikkanen, J.M.2
Bespalov, M.M.3
-
24
-
-
80051564190
-
Transient overexpression of Gremlinresults in epithelial activation and reversible fibrosis in rat lungs
-
Farkas L, Farkas D, Gauldie J, et al. Transient overexpression of Gremlinresults in epithelial activation and reversible fibrosis in rat lungs. Am JRespir Cell Mol Biol 2011;44:870-878.
-
(2011)
Am JRespir Cell Mol Biol
, vol.44
, pp. 870-878
-
-
Farkas, L.1
Farkas, D.2
Gauldie, J.3
-
25
-
-
38849191640
-
Gremlin-mediateddecrease in bone morphogenetic protein signaling promotespulmonary fibrosis
-
Myllarniemi M, Lindholm P, Ryynanen MJ, et al. Gremlin-mediateddecrease in bone morphogenetic protein signaling promotespulmonary fibrosis. Am J Respir Crit Care Med 2008;177:321-329.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 321-329
-
-
Myllarniemi, M.1
Lindholm, P.2
Ryynanen, M.J.3
-
26
-
-
84880652115
-
Pulmonary expression ofoncostatin M (OSM) promotes inducible BALT formationindependently of IL-6, despite a role for IL-6 in OSM-drivenpulmonary inflammation
-
Botelho FM, Rangel-Moreno J, Fritz D, et al. Pulmonary expression ofoncostatin M (OSM) promotes inducible BALT formationindependently of IL-6, despite a role for IL-6 in OSM-drivenpulmonary inflammation. J Immunol 2013;191:1453-1464.
-
(2013)
J Immunol
, vol.191
, pp. 1453-1464
-
-
Botelho, F.M.1
Rangel-Moreno, J.2
Fritz, D.3
-
27
-
-
33646064471
-
Oncostatin-M up-regulates VCAM-1 andsynergizes with IL-4 in eotaxin expression: Involvement of STAT6
-
Fritz DK, Kerr C, Tong L, et al. Oncostatin-M up-regulates VCAM-1 andsynergizes with IL-4 in eotaxin expression: Involvement of STAT6.J Immunol 2006;176:4352-4360.
-
(2006)
J Immunol
, vol.176
, pp. 4352-4360
-
-
Fritz, D.K.1
Kerr, C.2
Tong, L.3
-
28
-
-
33750982120
-
Stattic: A small-molecule inhibitor ofSTAT3 activation and dimerization
-
Schust J, Sperl B, Hollis A, et al. Stattic: A small-molecule inhibitor ofSTAT3 activation and dimerization. Chem Biol 2006;13:1235-1242.
-
(2006)
Chem Biol
, vol.13
, pp. 1235-1242
-
-
Schust, J.1
Sperl, B.2
Hollis, A.3
-
29
-
-
79959377314
-
Diminished type III collagenpromotes myofibroblast differentiation and increases scar depositionin cutaneous wound healing
-
Volk SW, Wang Y, Mauldin EA, et al. Diminished type III collagenpromotes myofibroblast differentiation and increases scar depositionin cutaneous wound healing. Cells Tissues Organs 2011;194:25-37.
-
(2011)
Cells Tissues Organs
, vol.194
, pp. 25-37
-
-
Volk, S.W.1
Wang, Y.2
Mauldin, E.A.3
-
30
-
-
0023925814
-
Type i and type III collagencontent of healing wounds in fetal and adult rats
-
Merkel JR, DiPaolo BR, Hallock GG, et al. Type I and type III collagencontent of healing wounds in fetal and adult rats. Proc Soc Exp BiolMed 1988;187:493-497.
-
(1988)
Proc Soc Exp BiolMed
, vol.187
, pp. 493-497
-
-
Merkel, J.R.1
Dipaolo, B.R.2
Hallock, G.G.3
-
31
-
-
84876680937
-
The IL-6 trans-signaling-STAT3 pathwaymediates ECM and cellular proliferation in fibroblasts from hypertrophicscar
-
Ray S, Ju X, Sun H, et al. The IL-6 trans-signaling-STAT3 pathwaymediates ECM and cellular proliferation in fibroblasts from hypertrophicscar. J Invest Dermatol 2013;133:1212-1220.
-
(2013)
J Invest Dermatol
, vol.133
, pp. 1212-1220
-
-
Ray, S.1
Ju, X.2
Sun, H.3
-
32
-
-
84859015820
-
STAT3-mediated signalingdysregulates lung fibroblast-myofibroblast activation anddifferentiation in UIP/IPF
-
Pechkovsky DV, Prê le CM, Wong J, et al. STAT3-mediated signalingdysregulates lung fibroblast-myofibroblast activation anddifferentiation in UIP/IPF. Am J Pathol 2012;180:1398-1412.
-
(2012)
Am J Pathol
, vol.180
, pp. 1398-1412
-
-
Pechkovsky, D.V.1
Prê Le, C.M.2
Wong, J.3
-
33
-
-
44849139210
-
GP130-STAT3 regulatesepithelial cell migration and is required for repair of the bronchiolarepithelium
-
Kida H, Mucenski ML, Thitoff AR, et al. GP130-STAT3 regulatesepithelial cell migration and is required for repair of the bronchiolarepithelium. Am J Pathol 2008;172:1542-1554.
-
(2008)
Am J Pathol
, vol.172
, pp. 1542-1554
-
-
Kida, H.1
Mucenski, M.L.2
Thitoff, A.R.3
-
34
-
-
78649808684
-
Bone morphogenetic proteinsignalling in airway epithelial cells during regeneration
-
Masterson JC, Molloy EL, Gilbert JL, et al. Bone morphogenetic proteinsignalling in airway epithelial cells during regeneration. Cell Signal2011;23:398-406.
-
(2011)
Cell Signal
, vol.23
, pp. 398-406
-
-
Masterson, J.C.1
Molloy, E.L.2
Gilbert, J.L.3
-
35
-
-
77956677107
-
Bone morphogenetic protein(BMP)-4 and BMP-7 regulate differentially transforming growth factor(TGF)-beta1 in normal human lung fibroblasts (NHLF)
-
Pegorier S, Campbell GA, Kay AB, et al. Bone morphogenetic protein(BMP)-4 and BMP-7 regulate differentially transforming growth factor(TGF)-beta1 in normal human lung fibroblasts (NHLF). Respir Res 2010;11:85.
-
(2010)
Respir Res
, vol.11
, pp. 85
-
-
Pegorier, S.1
Campbell, G.A.2
Kay, A.B.3
-
36
-
-
33644813656
-
BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblaststhrough Id2
-
Izumi N, Mizuguchi S, Inagaki Y, et al. BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblaststhrough Id2. Am J Physiol Lung Cell Mol Physiol 2006;290:L120-L126.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Izumi, N.1
Mizuguchi, S.2
Inagaki, Y.3
-
37
-
-
26844435631
-
The eotaxin chemokinesand CCR3 are fundamental regulators of allergen-induced pulmonaryeosinophilia
-
Pope SM, Zimmermann N, Stringer KF, et al. The eotaxin chemokinesand CCR3 are fundamental regulators of allergen-induced pulmonaryeosinophilia. J Immunol 2005;175:5341-5350.
-
(2005)
J Immunol
, vol.175
, pp. 5341-5350
-
-
Pope, S.M.1
Zimmermann, N.2
Stringer, K.F.3
-
38
-
-
17144362809
-
Identification of a cooperativemechanism involving interleukin-13 and eotaxin-2 in experimentalallergic lung inflammation
-
Pope SM, Fulkerson PC, Blanchard C, et al. Identification of a cooperativemechanism involving interleukin-13 and eotaxin-2 in experimentalallergic lung inflammation. J Biol Chem 2005;280:13952-13961.
-
(2005)
J Biol Chem
, vol.280
, pp. 13952-13961
-
-
Pope, S.M.1
Fulkerson, P.C.2
Blanchard, C.3
-
39
-
-
0032055808
-
Regulation of allergic inflammationand eosinophil recruitment in mice lacking the transcription factorNFAT1: Role of interleukin-4 (IL-4) and IL-5
-
Viola JP, Kiani A, Bozza PT, et al. Regulation of allergic inflammationand eosinophil recruitment in mice lacking the transcription factorNFAT1: Role of interleukin-4 (IL-4) and IL-5. Blood 1998;91:2223-2230.
-
(1998)
Blood
, vol.91
, pp. 2223-2230
-
-
Viola, J.P.1
Kiani, A.2
Bozza, P.T.3
-
40
-
-
11144303200
-
Attenuated allergic airwayhyperresponsiveness in C57BL/6 mice is associated with enhancedsurfactant protein (SP)-D production following allergic sensitization
-
Atochina EN, Beers MF, Tomer Y, et al. Attenuated allergic airwayhyperresponsiveness in C57BL/6 mice is associated with enhancedsurfactant protein (SP)-D production following allergic sensitization.Respir Res 2003;4:15.
-
(2003)
Respir Res
, vol.4
, pp. 15
-
-
Atochina, E.N.1
Beers, M.F.2
Tomer, Y.3
-
41
-
-
37549060626
-
The role of inflammationin the pathogenesis of idiopathic pulmonary fibrosis
-
Bringardner BD, Baran CP, Eubank TD, et al. The role of inflammationin the pathogenesis of idiopathic pulmonary fibrosis. Antioxid RedoxSignal 2008;10:287-301.
-
(2008)
Antioxid RedoxSignal
, vol.10
, pp. 287-301
-
-
Bringardner, B.D.1
Baran, C.P.2
Eubank, T.D.3
-
42
-
-
22644446181
-
Treatment of idiopathicpulmonary fibrosis: Is there anything new?
-
Abdelaziz MM, Samman YS, Wali SO, et al. Treatment of idiopathicpulmonary fibrosis: Is there anything new? Respirology 2005;10:284-289.
-
(2005)
Respirology
, vol.10
, pp. 284-289
-
-
Abdelaziz, M.M.1
Samman, Y.S.2
Wali, S.O.3
-
43
-
-
84893797280
-
The epithelium in idiopathicpulmonary fibrosis: Breaking the barrier
-
Camelo A, Dunmore R, Sleeman MA, et al. The epithelium in idiopathicpulmonary fibrosis: Breaking the barrier. Front Pharmacol 2014;4:173.
-
(2014)
Front Pharmacol
, vol.4
, pp. 173
-
-
Camelo, A.1
Dunmore, R.2
Sleeman, M.A.3
-
44
-
-
80955151564
-
Interstitial lung disease:physiopathology in the context of lung growth
-
Nathan N, Thouvenin G, Fauroux B, et al. Interstitial lung disease:physiopathology in the context of lung growth. Paediatr Respir Rev2011;12:216-222.
-
(2011)
Paediatr Respir Rev
, vol.12
, pp. 216-222
-
-
Nathan, N.1
Thouvenin, G.2
Fauroux, B.3
-
45
-
-
9144254680
-
Oncostatin M, a cytokinereleased by activated mononuclear cells induces epithelial cellmyofibroblasttransdifferentiation via Jak/Stat pathway activation
-
Nightingale J, Patel S, Suzuki N, et al. Oncostatin M, a cytokinereleased by activated mononuclear cells, induces epithelial cellmyofibroblasttransdifferentiation via Jak/Stat pathway activation.J Am Soc Nephrol 2004;15:21-32.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 21-32
-
-
Nightingale, J.1
Patel, S.2
Suzuki, N.3
-
46
-
-
36048949007
-
Oncostatin M-induced effects onEMT in human proximal tubular cells: Differential role of ERK signaling
-
Pollack V, Sarközi R, Banki Z, et al. Oncostatin M-induced effects onEMT in human proximal tubular cells: Differential role of ERK signaling.Am J Physiol Renal Physiol 2007;293:F1714-F1726.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Pollack, V.1
Sarközi, R.2
Banki, Z.3
|