A systems biology approach reveals a link between systemic cytokines and skeletal muscle energy metabolism in a rodent smoking model and human COPD

Genome Medicine

Volumn 6, Issue 8, 2014, Pages

  Davidsen, Peter K ^a,b   Herbert, John M ^a   Antczak, Philipp ^a   Clarke, Kim ^a   Ferrer, Elisabet ^c,d   Peinado, Victor I ^c,d,e   Gonzalez, Constancio ^e,f   Roca, Josep ^c,d,e   Egginton, Stuart ^g   Barberá, Joan A ^c,d,e   Falciani, Francesco ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF BARCELONA   (Spain)

^d INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f UNIVERSITY OF VALLADOLID   (Spain)

^g UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; CXCL9 CHEMOKINE; EOTAXIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PROTEASOME; RANTES; VASCULOTROPIN RECEPTOR;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CITRIC ACID CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENERGY METABOLISM; EXTRACELLULAR MATRIX; FOCAL ADHESION; GASTROCNEMIUS MUSCLE; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GLYCOLYSIS; GUINEA PIG MODEL; HINDLIMB; HUMAN; HUMAN TISSUE; HYPOXIA; LONG TERM EXPOSURE; LUNG PARENCHYMA; MALE; MUSCLE ATROPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE PHOSPHORYLATION; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; QUADRICEPS FEMORIS MUSCLE; RIBOSOME; RNA SEQUENCE; SENSITIVITY AND SPECIFICITY; SKELETAL MUSCLE; SMOKING; SOLEUS MUSCLE; SYSTEMS BIOLOGY; UPREGULATION; WNT SIGNALING PATHWAY;

EID: 84906834126     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-014-0059-5     Document Type: Article

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