Formulation and in vitro and in vivo evaluation of a cationic emulsion as a vehicle for improving adenoviral gene transfer

International Journal of Pharmaceutics

Volumn 475, Issue 1-2, 2014, Pages 49-59

  Kim, Soo Yeon ^a   Lee, Sang Jin ^b   Lim, Soo Jeong ^a  

^a Sejong University   (South Korea)

^b National Cancer Center   (South Korea)

Author keywords

Adenovirus; Cationic emulsion; Caveolin; Endocytosis; Gene therapy

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ADENOVIRUS VECTOR; IODINATED POPPYSEED OIL; EMULSION; GREEN FLUORESCENT PROTEIN; LIPOSOME; RECOMBINANT DNA; RECOMBINANT PROTEIN;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CAVEOLA; CONTROLLED STUDY; DRUG FORMULATION; EMULSION; ENDOCYTOSIS; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ADENOVIRIDAE; ADMINISTRATION AND DOSAGE; ADVERSE EFFECTS; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; CHEMISTRY; COMPARATIVE STUDY; GENE VECTOR; GENETICS; LUNG; MALE; METABOLISM; RANDOMIZATION; TUMOR CELL LINE; VIRION; VIROLOGY; VIRUS ATTACHMENT; VIRUS ENTRY;

ADENOVIRIDAE; ANIMALS; CELL LINE, TUMOR; DNA, RECOMBINANT; EMULSIONS; ENDOCYTOSIS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LIPOSOMES; LUNG; MALE; MICE, INBRED C57BL; ORGAN SPECIFICITY; RANDOM ALLOCATION; RECOMBINANT PROTEINS; VIRION; VIRUS ATTACHMENT; VIRUS INTERNALIZATION;

EID: 84906726984     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.08.024     Document Type: Article

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