Ketamine inhibits LPS-induced HGMB1 release in vitro and in vivo

International Immunopharmacology

Volumn 23, Issue 1, 2014, Pages 14-26

  Zhang, Zhaohang ^a   Zhang, Li ^a   Zhou, Changqing ^a   Wu, Hui ^b  

^a SHANDONG UNIVERSITY   (China)

^b Department of Anesthesiology Zhangqiu People's Hospital   (China)

Author keywords

HMGB1 protein; Ketamine; Lipopolysaccharides; NF B; p38 MAPK; Sepsis

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; KETAMINE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; PROTEIN; PROTEIN SERINE THREONINE KINASE INHIBITOR; PYRIMIDINE DITHIOCARBAMATE; UNCLASSIFIED DRUG; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MEDIATOR RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEPSIS; SURVIVAL TIME; WESTERN BLOTTING; DOSE RESPONSE; GENE TRANSLOCATION; HEART INJURY; IMMUNOPROPHYLAXIS; KIDNEY INJURY; LIVER INJURY; ORGAN INJURY; PRIMARY CELL; SURVIVAL RATE; TREATMENT RESPONSE; ANIMAL; ANTAGONISTS AND INHIBITORS; CECUM; CELL LINE; DISEASE MODEL; DRUG EFFECTS; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; PERITONITIS; SPRAGUE DAWLEY RAT; SURGERY;

ANIMALS; CECUM; CELL LINE; DISEASE MODELS, ANIMAL; HMGB1 PROTEIN; HUMANS; IMIDAZOLES; KETAMINE; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERITONITIS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS;

EID: 84906705334     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.08.003     Document Type: Article

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