Penehyclidine hydrochloride inhibits the release of high-mobility group box 1 in lipopolysaccharide-activated RAW264.7 cells and cecal ligation and puncture-induced septic mice

Journal of Surgical Research

Volumn 186, Issue 1, 2014, Pages 310-317

  Yang, Qiang ^a   Liu, Xiangge ^a   Yao, Zhongyan ^a   Mao, Shunhong ^a   Wei, Qianjie ^a   Chang, Yulin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

HMGB1 protein; Lipopolysaccharides; NF B; Penehyclidine hydrochloride; Sepsis

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIINFLAMMATORY AGENT; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; CREATININE; HIGH MOBILITY GROUP B1 PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITROGEN; PENEHYCLIDINE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CECUM; CELL NUCLEUS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HEART PROTECTION; LABORATORY DEVICE; LIGATION; LIVER PROTECTION; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; RENAL PROTECTION; SEPSIS; SIGNAL TRANSDUCTION; SUPERNATANT; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING;

HMGB1 PROTEIN; LIPOPOLYSACCHARIDES; NF-ΚB; PENEHYCLIDINE HYDROCHLORIDE; SEPSIS;

ANIMALS; APOPTOSIS; CECUM; CELL SURVIVAL; CELLS, CULTURED; CHOLINERGIC ANTAGONISTS; HMGB1 PROTEIN; LIGATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; NF-KAPPA B; PROTEIN TRANSPORT; QUINUCLIDINES; SEPSIS;

EID: 84890118383     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.08.015     Document Type: Article

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