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Volumn 25, Issue 5, 2014, Pages 1013-1027

Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

ARISTOLOCHIC ACID; BUPRENORPHINE; COLLAGEN; CREATININE; HYDROXYPROLINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; SYNDECAN 4; TRANSFORMING GROWTH FACTOR BETA1; ARISTOLOCHIC ACID I; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SDC4 PROTEIN, MOUSE; TGFB1 PROTEIN, MOUSE;

EID: 84906540104     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013050563     Document Type: Article
Times cited : (57)

References (54)
  • 3
    • 0036016840 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their inhibitions in experimental renal scarring
    • Johnson TS, Haylor JL, Thomas GL, Fisher M, El Nahas AM: Matrix metalloproteinases and their inhibitions in experimental renal scarring. Exp Nephrol 10: 182-195, 2002
    • (2002) Exp Nephrol , vol.10 , pp. 182-195
    • Johnson, T.S.1    Haylor, J.L.2    Thomas, G.L.3    Fisher, M.4    El Nahas, A.M.5
  • 4
    • 0034743940 scopus 로고    scopus 로고
    • Increases in renal epsilon-(gamma-glutamyl)-lysine crosslinks result from compartment-specific changes in tissue transglutaminase in early experimental diabetic nephropathy: Pathologic implications
    • Skill NJ, GriffinM, El Nahas AM, Sanai T, Haylor JL, FisherM, Jamie MF, Mould NN, Johnson TS: Increases in renal epsilon-(gamma-glutamyl)-lysine crosslinks result from compartment-specific changes in tissue transglutaminase in early experimental diabetic nephropathy: pathologic implications. Lab Invest 81: 705-716, 2001
    • (2001) Lab Invest , vol.81 , pp. 705-716
    • Skill, N.J.1    Griffinm El Nahas, A.M.2    Sanai, T.3    Haylor, J.L.4    Fisherm Jamie, M.F.5    Mould, N.N.6    Johnson, T.S.7
  • 6
    • 0030974902 scopus 로고    scopus 로고
    • Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta
    • Nunes I, Gleizes PE, Metz CN, Rifkin DB: Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta. J Cell Biol 136: 1151-1163, 1997
    • (1997) J Cell Biol , vol.136 , pp. 1151-1163
    • Nunes, I.1    Gleizes, P.E.2    Metz, C.N.3    Rifkin, D.B.4
  • 7
    • 79961159239 scopus 로고    scopus 로고
    • Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treatedmice
    • Oh K, Park HB, ByounOJ, ShinDM, Jeong EM, KimYW, KimYS,Melino G, Kim IG, Lee DS: Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treatedmice. J Exp Med 208: 1707-1719, 2011
    • (2011) J Exp Med , vol.208 , pp. 1707-1719
    • Oh, K.1    Park, H.B.2    Byoun, O.J.3    Shin, D.M.4    Jeong, E.M.5    Kim, Y.W.6    Kim, Y.S.7    Melino, G.8    Kim, I.G.9    Lee, D.S.10
  • 8
    • 51349086373 scopus 로고    scopus 로고
    • Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration
    • Shweke N, Boulos N, Jouanneau C, Vandermeersch S, Melino G, Dussaule JC, Chatziantoniou C, Ronco P, Boffa JJ: Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration. Am J Pathol 173: 631-642, 2008
    • (2008) Am J Pathol , vol.173 , pp. 631-642
    • Shweke, N.1    Boulos, N.2    Jouanneau, C.3    Vandermeersch, S.4    Melino, G.5    Dussaule, J.C.6    Chatziantoniou, C.7    Ronco, P.8    Boffa, J.J.9
  • 9
    • 0027419881 scopus 로고
    • Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells
    • Kojima S, Nara K, Rifkin DB: Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells. J Cell Biol 121: 439-448, 1993
    • (1993) J Cell Biol , vol.121 , pp. 439-448
    • Kojima, S.1    Nara, K.2    Rifkin, D.B.3
  • 10
    • 0037317032 scopus 로고    scopus 로고
    • Transglutaminases: Crosslinking enzymes with pleiotropic functions
    • Lorand L, Graham RM: Transglutaminases: Crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 4: 140-156, 2003
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 140-156
    • Lorand, L.1    Graham, R.M.2
  • 13
    • 4043066599 scopus 로고    scopus 로고
    • Elevated epsilon-(gamma-glutamyl)lysine in human diabetic nephropathy results from increased expression and cellular release of tissue transglutaminase
    • El Nahas AM, Abo-Zenah H, Skill NJ, Bex S,Wild G, GriffinM, Johnson TS: Elevated epsilon-(gamma-glutamyl)lysine in human diabetic nephropathy results from increased expression and cellular release of tissue transglutaminase. Nephron Clin Pract 97: c108-c117, 2004
    • (2004) Nephron Clin Pract , vol.97 , pp. c108-c117
    • El Nahas, A.M.1    Abo-Zenah, H.2    Skill, N.J.3    Bex Swild, G.4    Griffin, M.5    Johnson, T.S.6
  • 15
    • 0034855522 scopus 로고    scopus 로고
    • Transglutaminase-mediated cross-linking is involved in the stabilization of extracellular matrix in human liver fibrosis
    • Grenard P, Bresson-Hadni S, El Alaoui S, Chevallier M, Vuitton DA, Ricard-Blum S: Transglutaminase-mediated cross-linking is involved in the stabilization of extracellular matrix in human liver fibrosis. JHepatol 35: 367-375, 2001
    • (2001) JHepatol , vol.35 , pp. 367-375
    • Grenard, P.1    Bresson-Hadni, S.2    El Alaoui, S.3    Chevallier, M.4    Vuitton, D.A.5    Ricard-Blum, S.6
  • 17
    • 0142242157 scopus 로고    scopus 로고
    • A novel RGDindependent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis
    • Verderio EA, Telci D, Okoye A, Melino G, Griffin M: A novel RGDindependent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis. J Biol Chem 278: 42604-42614, 2003
    • (2003) J Biol Chem , vol.278 , pp. 42604-42614
    • Verderio, E.A.1    Telci, D.2    Okoye, A.3    Melino, G.4    Griffin, M.5
  • 18
    • 51049089580 scopus 로고    scopus 로고
    • Fibronectin-tissue transglutaminase matrix rescues RGDimpaired cell adhesion through syndecan-4 and beta1 integrin cosignaling
    • Telci D,Wang Z, Li X, Verderio EA, Humphries MJ, Baccarini M, Basaga H, Griffin M: Fibronectin-tissue transglutaminase matrix rescues RGDimpaired cell adhesion through syndecan-4 and beta1 integrin cosignaling. J Biol Chem283: 20937-20947, 2008
    • (2008) J Biol Chem , vol.283 , pp. 20937-20947
    • Telci Dwang, Z.1    Li, X.2    Verderio, E.A.3    Humphries, M.J.4    Baccarini, M.5    Basaga, H.6    Griffin, M.7
  • 19
    • 82755187317 scopus 로고    scopus 로고
    • Extracellular TG2: Emerging functions and regulation
    • Belkin AM: Extracellular TG2: Emerging functions and regulation. FEBS J 278: 4704-4716, 2011
    • (2011) FEBS J , vol.278 , pp. 4704-4716
    • Belkin, A.M.1
  • 20
    • 84871981788 scopus 로고    scopus 로고
    • Recent advances in the development of tissue transglutaminase (TG2) inhibitors
    • Badarau E, Collighan RJ, Griffin M: Recent advances in the development of tissue transglutaminase (TG2) inhibitors. Amino Acids 44: 119-127, 2013
    • (2013) Amino Acids , vol.44 , pp. 119-127
    • Badarau, E.1    Collighan, R.J.2    Griffin, M.3
  • 21
    • 79955692581 scopus 로고    scopus 로고
    • Unconventional secretion of tissue transglutaminase involves phospholipiddependent delivery into recycling endosomes
    • Zemskov EA, Mikhailenko I, Hsia RC, Zaritskaya L, Belkin AM: Unconventional secretion of tissue transglutaminase involves phospholipiddependent delivery into recycling endosomes. PLoS ONE 6: e19414, 2011
    • (2011) PLoS ONE , vol.6 , pp. e19414
    • Zemskov, E.A.1    Mikhailenko, I.2    Hsia, R.C.3    Zaritskaya, L.4    Belkin, A.M.5
  • 22
    • 79961009222 scopus 로고    scopus 로고
    • A crucial sequence for transglutaminase type 2 extracellular trafficking in renal tubular epithelial cells lies in its N-terminal beta-sandwich domain
    • Chou CY, Streets AJ, Watson PF, Huang L, Verderio EA, Johnson TS: A crucial sequence for transglutaminase type 2 extracellular trafficking in renal tubular epithelial cells lies in its N-terminal beta-sandwich domain. J Biol Chem 286: 27825-27835, 2011
    • (2011) J Biol Chem , vol.286 , pp. 27825-27835
    • Chou, C.Y.1    Streets, A.J.2    Watson, P.F.3    Huang, L.4    Verderio, E.A.5    Johnson, T.S.6
  • 23
    • 67650513329 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2
    • Scarpellini A, Germack R, Lortat-Jacob H, Muramatsu T, Billett E, Johnson T, Verderio EA: Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2. J Biol Chem 284: 18411-18423, 2009
    • (2009) J Biol Chem , vol.284 , pp. 18411-18423
    • Scarpellini, A.1    Germack, R.2    Lortat-Jacob, H.3    Muramatsu, T.4    Billett, E.5    Johnson, T.6    Verderio, E.A.7
  • 24
    • 84861557321 scopus 로고    scopus 로고
    • Transglutaminase-2 interaction with heparin: Identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix
    • Lortat-Jacob H, Burhan I, Scarpellini A, Thomas A, Imberty A, Vivès RR, Johnson T, Gutierrez A, Verderio EA: Transglutaminase-2 interaction with heparin: Identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix. J Biol Chem 287: 18005-18017, 2012
    • (2012) J Biol Chem , vol.287 , pp. 18005-18017
    • Lortat-Jacob, H.1    Burhan, I.2    Scarpellini, A.3    Thomas, A.4    Imberty, A.5    Vivès, R.R.6    Johnson, T.7    Gutierrez, A.8    Verderio, E.A.9
  • 25
    • 33750299160 scopus 로고    scopus 로고
    • Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2
    • Zehe C, Engling A, Wegehingel S, Schäfer T, Nickel W: Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2. Proc Natl Acad Sci U S A 103: 15479-15484, 2006
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15479-15484
    • Zehe, C.1    Engling, A.2    Wegehingel, S.3    Schäfer, T.4    Nickel, W.5
  • 26
    • 0035018302 scopus 로고    scopus 로고
    • Cell surface heparan sulfate proteoglycans control the response of renal interstitial fibroblasts to fibroblast growth factor-2
    • Clayton A, Thomas J, Thomas GJ, Davies M, Steadman R: Cell surface heparan sulfate proteoglycans control the response of renal interstitial fibroblasts to fibroblast growth factor-2. Kidney Int 59: 2084-2094, 2001
    • (2001) Kidney Int , vol.59 , pp. 2084-2094
    • Clayton, A.1    Thomas, J.2    Thomas, G.J.3    Davies, M.4    Steadman, R.5
  • 27
    • 0035406885 scopus 로고    scopus 로고
    • Syndecan-4 up-regulation in proliferative renal disease is related to microfilament organization
    • Yung S, Woods A, Chan TM, Davies M, Williams JD, Couchman JR: Syndecan-4 up-regulation in proliferative renal disease is related to microfilament organization. FASEB J 15: 1631-1633, 2001
    • (2001) FASEB J , vol.15 , pp. 1631-1633
    • Yung, S.1    Woods, A.2    Chan, T.M.3    Davies, M.4    Williams, J.D.5    Couchman, J.R.6
  • 30
    • 0034998747 scopus 로고    scopus 로고
    • Obstructive nephropathy in the mouse: Progressive fibrosis correlates with tubulointerstitial chemokine expression and accumulation ofCCchemokine receptor 2-and 5-positive leukocytes
    • Vielhauer V, Anders HJ, Mack M, Cihak J, Strutz F, Stangassinger M, Luckow B, Gröne HJ, Schlöndorff D: Obstructive nephropathy in the mouse: Progressive fibrosis correlates with tubulointerstitial chemokine expression and accumulation ofCCchemokine receptor 2-and 5-positive leukocytes. J Am Soc Nephrol 12: 1173-1187, 2001
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1173-1187
    • Vielhauer, V.1    Anders, H.J.2    Mack, M.3    Cihak, J.4    Strutz, F.5    Stangassinger, M.6    Luckow, B.7    Gröne, H.J.8    Schlöndorff, D.9
  • 32
    • 84899815905 scopus 로고    scopus 로고
    • Development of a chronic kidney disease model in C57BL/6 mice with relevance to human pathology
    • Huang L, Scarpellini A, Funck M, Verderio EA, Johnson TS: Development of a chronic kidney disease model in C57BL/6 mice with relevance to human pathology. Nephron Extra 3: 12-29, 2013
    • (2013) Nephron Extra , vol.3 , pp. 12-29
    • Huang, L.1    Scarpellini, A.2    Funck, M.3    Verderio, E.A.4    Johnson, T.S.5
  • 33
    • 0032728955 scopus 로고    scopus 로고
    • Regulation of cell surface tissue transglutaminase: Effects on matrix storage of latent transforming growth factor-beta binding protein-1
    • Verderio E, Gaudry C, Gross S, Smith C, Downes S, Griffin M: Regulation of cell surface tissue transglutaminase: effects on matrix storage of latent transforming growth factor-beta binding protein-1. J Histochem Cytochem 47: 1417-1432, 1999
    • (1999) J Histochem Cytochem , vol.47 , pp. 1417-1432
    • Verderio, E.1    Gaudry, C.2    Gross, S.3    Smith, C.4    Downes, S.5    Griffin, M.6
  • 34
    • 78649497500 scopus 로고    scopus 로고
    • Do changes in transglutaminase activity alter latent transforming growth factor beta activation in experimental diabetic nephropathy?
    • Huang L, Haylor JL, Fisher M, Hau Z, El Nahas AM, Griffin M, Johnson TS: Do changes in transglutaminase activity alter latent transforming growth factor beta activation in experimental diabetic nephropathy? Nephrol Dial Transplant 25: 3897-3910, 2010
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3897-3910
    • Huang, L.1    Haylor, J.L.2    Fisher, M.3    Hau, Z.4    El Nahas, A.M.5    Griffin, M.6    Johnson, T.S.7
  • 35
    • 0027418205 scopus 로고
    • Measurement of colocalization of objects in dual-color confocal images
    • Manders EMM, Verbeek FJ, Aten JA:Measurement of colocalization of objects in dual-color confocal images. J Microsc 169: 375-382, 1993
    • (1993) J Microsc , vol.169 , pp. 375-382
    • Manders, E.M.M.1    Verbeek, F.J.2    Aten, J.A.3
  • 37
    • 77949357520 scopus 로고    scopus 로고
    • Differential expression of proteoglycans in tissue remodeling and lymphangiogenesis after experimental renal transplantation in rats
    • Rienstra H, Katta K, Celie JW, van Goor H, Navis G, van den Born J, Hillebrands JL: Differential expression of proteoglycans in tissue remodeling and lymphangiogenesis after experimental renal transplantation in rats. PLoS ONE 5: e9095, 2010
    • (2010) PLoS ONE , vol.5 , pp. e9095
    • Rienstra, H.1    Katta, K.2    Celie, J.W.3    Van Goor, H.4    Navis, G.5    Van Den Born, J.6    Hillebrands, J.L.7
  • 38
    • 0028328817 scopus 로고
    • An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct
    • Abe M, Harpel JG,Metz CN, Nunes I, Loskutoff DJ, Rifkin DB: An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 216: 276-284, 1994
    • (1994) Anal Biochem , vol.216 , pp. 276-284
    • Abe, M.1    Harpel, J.G.2    Metz, C.N.3    Nunes, I.4    Loskutoff, D.J.5    Rifkin, D.B.6
  • 39
    • 1942501852 scopus 로고    scopus 로고
    • Syndecan-2 regulates transforming growth factor-beta signaling
    • Chen L, Klass C, Woods A: Syndecan-2 regulates transforming growth factor-beta signaling. J Biol Chem 279: 15715-15718, 2004
    • (2004) J Biol Chem , vol.279 , pp. 15715-15718
    • Chen, L.1    Klass, C.2    Woods, A.3
  • 40
    • 62949246706 scopus 로고    scopus 로고
    • Novel interactions of TG2 with heparan sulfate proteoglycans: Reflection on physiological implications
    • Verderio EA, Scarpellini A, Johnson TS: Novel interactions of TG2 with heparan sulfate proteoglycans: Reflection on physiological implications. Amino Acids 36: 671-677, 2009
    • (2009) Amino Acids , vol.36 , pp. 671-677
    • Verderio, E.A.1    Scarpellini, A.2    Johnson, T.S.3
  • 41
    • 0041630593 scopus 로고    scopus 로고
    • Chronic renal insufficiency in children: The 2001 Annual Report of the NAPRTCS
    • Seikaly MG, Ho PL, Emmett L, Fine RN, Tejani A: Chronic renal insufficiency in children: The 2001 Annual Report of the NAPRTCS. Pediatr Nephrol 18: 796-804, 2003
    • (2003) Pediatr Nephrol , vol.18 , pp. 796-804
    • Seikaly, M.G.1    Ho, P.L.2    Emmett, L.3    Fine, R.N.4    Tejani, A.5
  • 42
    • 0014885804 scopus 로고
    • Structural-functional correlations in renal disease. II. The correlations
    • Schainuck LI, Striker GE, Cutler RE, Benditt EP: Structural-functional correlations in renal disease. II. The correlations. Hum Pathol 1: 631-641, 1970
    • (1970) Hum Pathol , vol.1 , pp. 631-641
    • Schainuck, L.I.1    Striker, G.E.2    Cutler, R.E.3    Benditt, E.P.4
  • 43
    • 80053909027 scopus 로고    scopus 로고
    • Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo
    • FragiadakiM, Witherden AS, Kaneko T, Sonnylal S, Pusey CD, Bou-GhariosG, Mason RM: Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo. Matrix Biol 30: 396-403, 2011
    • (2011) Matrix Biol , vol.30 , pp. 396-403
    • Fragiadaki, M.1    Witherden, A.S.2    Kaneko, T.3    Sonnylal, S.4    Pusey, C.D.5    Bou-Gharios, G.6    Mason, R.M.7
  • 45
    • 34247610845 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans finetune mammalian physiology
    • Bishop JR, Schuksz M, Esko JD: Heparan sulphate proteoglycans finetune mammalian physiology. Nature 446: 1030-1037, 2007
    • (2007) Nature , vol.446 , pp. 1030-1037
    • Bishop, J.R.1    Schuksz, M.2    Esko, J.D.3
  • 46
    • 38349151637 scopus 로고    scopus 로고
    • Unilateral nephrectomy leads to up-regulation of syndecan-2-and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice
    • Cevikbas F, Schaefer L, Uhlig P, Robenek H, Theilmeier G, Echtermeyer F, Bruckner P: Unilateral nephrectomy leads to up-regulation of syndecan-2-and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice. Matrix Biol 27: 42-52, 2008
    • (2008) Matrix Biol , vol.27 , pp. 42-52
    • Cevikbas, F.1    Schaefer, L.2    Uhlig, P.3    Robenek, H.4    Theilmeier, G.5    Echtermeyer, F.6    Bruckner, P.7
  • 47
    • 84859644032 scopus 로고    scopus 로고
    • Characterization of heparin-binding site of tissue transglutaminase: Its importance in cell surface targeting, matrix deposition, and cell signaling
    • Wang Z, Collighan RJ, Pytel K, Rathbone DL, Li X, Griffin M: Characterization of heparin-binding site of tissue transglutaminase: Its importance in cell surface targeting, matrix deposition, and cell signaling. J Biol Chem287: 13063-13083, 2012
    • (2012) J Biol Chem , vol.287 , pp. 13063-13083
    • Wang, Z.1    Collighan, R.J.2    Pytel, K.3    Rathbone, D.L.4    Li, X.5    Griffin, M.6
  • 48
    • 28244436502 scopus 로고    scopus 로고
    • Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: Insights into pathological scarring in chronic fibrotic disease
    • Chen Y, Shi-Wen X, van Beek J, Kennedy L, McLeod M, Renzoni EA, Bou-Gharios G, Wilcox-Adelman S, Goetinck PF, Eastwood M, Black CM, Abraham DJ, Leask A: Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease. Am J Pathol 167: 1699-1711, 2005
    • (2005) Am J Pathol , vol.167 , pp. 1699-1711
    • Chen, Y.1    Shi-Wen, X.2    Van Beek, J.3    Kennedy, L.4    McLeod, M.5    Renzoni, E.A.6    Bou-Gharios, G.7    Wilcox-Adelman, S.8    Goetinck, P.F.9    Eastwood, M.10    Black, C.M.11    Abraham, D.J.12    Leask, A.13
  • 50
    • 85190341733 scopus 로고    scopus 로고
    • Development of a chronic kidney disease model in C57BL/6 mice that is relevant to human disease
    • Presented at the Birmingham, United Kingdom, June 6
    • Huang L, Johnson TS: Development of a chronic kidney disease model in C57BL/6 mice that is relevant to human disease. Presented at the BRS/RA Conference, Birmingham, United Kingdom, June 6, 2011.
    • (2011) BRS/RA Conference
    • Huang, L.1    Johnson, T.S.2
  • 51
    • 0037439630 scopus 로고    scopus 로고
    • Making sense of latent TGFbeta activation
    • Annes JP, Munger JS, Rifkin DB: Making sense of latent TGFbeta activation. J Cell Sci 116: 217-224, 2003
    • (2003) J Cell Sci , vol.116 , pp. 217-224
    • Annes, J.P.1    Munger, J.S.2    Rifkin, D.B.3
  • 53
    • 0032557443 scopus 로고    scopus 로고
    • Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney
    • van Kuppevelt TH, Dennissen MA, van Venrooij WJ, Hoet RM, Veerkamp JH: Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney. J Biol Chem 273: 12960-12966, 1998
    • (1998) J Biol Chem , vol.273 , pp. 12960-12966
    • Van Kuppevelt, T.H.1    Dennissen, M.A.2    Van Venrooij, W.J.3    Hoet, R.M.4    Veerkamp, J.H.5


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