A role for tissue transglutaminase in hepatic injury and fibrogenesis, and its regulation by NF-κB

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 272, Issue 2 35-2, 1997, Pages

  Mirza, Ahmed ^a   Liu, Shu Ling ^a   Frizell, Eduardo ^a   Zhu, Jianling ^a   Maddukuri, Sivar ^a   Martinez, José ^a   Davies, Peter ^b   Schwarting, Roland ^a   Norton, Pamela ^a   Zern, Mark A ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

cirrhosis; fibrosis; gene regulation; liver injury

Indexed keywords

CARBON TETRACHLORIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROGENESIS; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER CELL; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER INJURY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CROSS LINKING; RAT;

EID: 0030900790     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.2.g281     Document Type: Article

References (35)

1. Adams, D., K. Kao, F. Fark, and S. Pizzu. Effector mechanisms of cytolytically activated macrophages: secretion of cytolytic factor by activated macrophages and its relation to secreted neutral protease. J. Immunol. 124: 293-300, 1980.
2. Baeuerle, P. The inducible activator NF-κB: regulation of distinct protein subunits. Biochem. Biophys. Acta 1072: 63-80, 1991.
3. Berry, M., and B. Friend. High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structure study. J. Cell Biol. 43: 506-520, 1969.
4. Chirgwin, J., A. Przbyla, R. MacDonald, and W. Rutter. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18: 5294-5299, 1979.
5. Chomczynski, P., and N. Sacchi. Single-step method of RNA extraction by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
6. Czaja, M., K. Flanders, L. Biempica, and C. Klein. Expression of tumor necrosis factor and transforming growth factor-β1 in acute rat liver injury. Growth Factors 1: 219-226, 1989.
7. Derynck, R., J. Jarrett, Y. Chen, D. Eaton, J. Bell, K. Assoian, A. Roberts, M. Sporn, and D. Goelddel. Human transforming growth factor-β cDNA sequence and expression in tumor cell lines. Nature Lond. 316: 701-705, 1985.
8. Fesus, L., and V. Thomazy. Searching for the function of tissue transglutaminase: its possible involvement in the biochemical pathway of programmed cell death. Adv. Exp. Med. Biol. 231: 119-134, 1988.
9. Folk, J., and J. Finlayson. The ∈-(γ-glutamyl) lysine cross link and the catalytic role of transglutaminases. Adv. Protein Chem. 31: 121-133, 1970.
10. Friedman, S. The cellular basis of hepatic fibrosis: mechanisms and treatment strategies. N. Engl. J. Med. 328: 1828-1835, 1993.
11. Frizell, E., S.-L. Liu, A. Abraham, I. Ozaki, and M. A. Zern. Expression of SPARC in normal and fibrotic livers. Hepatology 21: 847-854, 1995.
12. Fukuda, K., M. Kojiro, and J.-F. Chiu. Cross-linked cytokeratin polypeptides in liver and hepatoma cells: possible association with the process of cell degeneration and death. Hepatology 17: 118-123, 1993.
13. Fukuda, K., M. Kojiro, and J.-F. Chiu. Induction of apoptosis by transforming growth factor-β1 in the rat hepatoma cell line McA-RH7777: a possible association with tissue transglutaminase expression. Hepatology 18: 945-953, 1993.
14. Gentile, V., M. Saydak, E. Chiocca, O. Akande, P. Birckbichler, K. Lee, J. Stein, and P. Davies. Isolation and characterization of DNA clones to mouse macrophage and human endothelial cell tissue transglutaminase. J. Biol. Chem. 266: 478-483, 1990.
15. Gorski, K., M. Carneiro, and R. Schibler. Tissue specific in vitro transcription from the mouse albumin promoter. Cell 47: 767-776, 1986.
16. Greenberg, C., P. Birckbichler, and R. Rice. Transglutaminases: multifunctional cross-linking enzymes that stabilize tissue. FASEB J. 5: 3071-3077, 1991.
17. Griffin, M., L. Smith, and J. Waynne. Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. Br. J. Exp. Pathol. 60: 653-661, 1979.
18. Knook, D., A. Seffelar, and A. deLeeuw. Fat storing cells of the rat liver. Exp. Cell Res. 139: 468-471, 1982.
19. Knook, D., and E. Sleyster. Separation of Kupffer and endothelial cells of the rat liver by centrifugal elutriation. Exp. Cell Res. 99: 444-449, 1976.
20. Kojima, S., K. Nara, and D. Rifkin. Requirement for transglutaminase in the activation of latent transforming growth factor-β in bovine endothelial cells. J. Cell Biol. 121: 439-448, 1993.
21. Lawn, R., J. Adelman, S. Bock, A. Franke, C. Houck, R. Najarian, and P. Seeburg. The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res. 9: 6103-6114, 1981.
22. Leffert, H., K. Koch, T. Moran, and M. Williams. Liver cells. Methods Enzymol. 58: 536-544, 1979.
23. Liu, J.-K., Y. Bergman, and K. Zaret. The mouse albumin promoter and a distal upstream site are simultaneously DNase I hypersensitive in liver chromatin and bind similar liver-abundant factors in vivo. Genes Dev. 2: 528-541, 1988.
24. 4-induced hepatic injury in mice is associated with inhibition of NF-κB binding. Hepatology 22: 1474-1481, 1995.
25. Lorand, L., L. Cambell-Wilkes, and L. Cooperstein. A filter paper assay for transamidating enzymes using radioactive amine substrates. Anal. Biochem. 50: 623-632, 1972.
26. Lu, S., M. Saydak, V. Gentile, J. Stein, and P. Davies. Isolation and characterization of the human tissue transglutaminase gene promoter. J. Biol. Chem. 270: 9748-9756, 1995.
27. Martinez, J., D. Chalupowicz, R. Rouch, A. Sheth, and C. Barsigian. Transglutaminase-mediated processing of fibronectin by endothelial cell monolayers. Biochemistry 33: 2538-2545, 1994.
28. Merlino, G., I. Annicchiarico-Petruzzell, L. Piredda, E. Candi, V. Gentile, P. Davies, and M. Piacentini. Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol. Cell. Biol. 14: 6584-6596, 1994.
29. Nagy, L., and P. Davies. Retinoid-regulated expression of BCL-2 and tissue transglutaminase during the differentiation and apoptosis of human myeloid leukemia (HL-60) cells. Leuk. Res. In press.
30. Okuno, M., and Y. Muto. Plasmin inhibitors suppress the release and activation of transforming growth factor-β in rat stellate cell cultures (Abstract). Int. Hepatol. Comm. 3: 89, 1995.
31. Prestridge, D. SIGNAL SCAN: a computer program that scans DNA sequences for eukaryotic transcriptional elements. CABIOS 7: 203-206, 1991.
32. Reid, L. Defining hormone and matrix requirements for differentiated epithelia. In: Methods in Molecular Biology, edited by J. W. Polland and J. M. Walker. Clifton, NJ: Humana, 1990, vol. 5, p. 237-274.
33. Schrect, R., B. Meier, D. Mannel, W. Droge, and P. Baeuerle. Dithiocarbamates as potent inhibitors of nuclear factor-κB activation in intact cells. J. Exp. Med. 175: 1181-1194, 1992.
34. Upchurch, H., E. Conway, M. J. Patterson, P. Birckbichler, and M. Maxwell. Cellular transglutaminase has affinity for extracellular matrix. In Vitro Cell. Dev. Biol. 795-800, 1987.
35. Upchurch, H., E. Conway, M. J. Patterson, and M. Maxwell. Localization of cellular transglutaminase on the extracellular matrix after wounding: characteristics of the matrix bound enzyme. J. Cell. Physiol. 149: 375-382, 1991.