Behavior of encapsulated MG-63 cells in RGD and gelatine-modified alginate hydrogels

Tissue Engineering - Part A

Volumn 20, Issue 15-16, 2014, Pages 2140-2150

  Grigore, Alexandra ^a   Sarker, Bapi ^a   Fabry, Ben ^a   Boccaccini, Aldo R ^a   Detsch, Rainer ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINATE; CELL ADHESION; CELL CULTURE; CELL ENGINEERING; ENCAPSULATION; ENDOTHELIAL CELLS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HYDROGELS; PHYSIOLOGY;

BIOLOGICAL PROPERTIES; CELL ENCAPSULATIONS; COVALENTLY CROSS-LINKED; MICROENCAPSULATION TECHNOLOGY; SPHERICAL AGGREGATES; THREE DIMENSIONAL CELL CULTURE; TISSUE ENGINEERING SCAFFOLDING; VASCULAR ENDOTHELIAL GROWTH FACTOR;

SCAFFOLDS (BIOLOGY);

ALGINIC ACID; ARGINYLGLYCYLASPARTIC ACID; GELATIN; VASCULOTROPIN; ARGINYL-GLYCYL-ASPARTIC ACID; GLUCURONIC ACID; HEXURONIC ACID; HYDROGEL; OLIGOPEPTIDE; VASCULOTROPIN A;

ARTICLE; CELL ADHESION; CELL ENCAPSULATION; CELL FUNCTION; CELL METABOLISM; CELL MOTILITY; CELL STRUCTURE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; FLUORESCENCE MICROSCOPY; HYDROGEL; INFRARED SPECTROSCOPY; MICROCAPSULE; MICROENCAPSULATION; MICROTECHNOLOGY; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN SECRETION; SCANNING ELECTRON MICROSCOPY; STORAGE; TISSUE ENGINEERING; YOUNG MODULUS; ACTIN FILAMENT; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; HUMAN; IMMOBILIZED CELL; METABOLISM; PHARMACOLOGY; PIG; SECRETION (PROCESS);

ACTIN CYTOSKELETON; ALGINATES; ANIMALS; CELL LINE; CELLS, IMMOBILIZED; ELASTIC MODULUS; GELATIN; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; HYDROGELS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; OLIGOPEPTIDES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUS SCROFA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84906534825     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2013.0416     Document Type: Article

References (60)

1. Rowley, J.A., Madlambayan, G., and Mooney, D.J. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 20, 45, 1999.
2. Murua, A., Portero,A., Orive, G.,Hernández,R.M., deCastro, M., and Pedraz, J.L. Cell microencapsulation technology: Towards clinical application. J Control Release 132, 76, 2008.
3. Awad, H.A., Wickham, M.Q., Leddy, H.A., Gimble, J.M., and Guilak, F. Chondrogenic differentiation of adiposederived adult stem cells in agarose, alginate, and gelatin scaffolds. Biomaterials 25, 3211, 2004.
4. Jen, A.C., Wake, M.C., and Mikos, A.G. Review: Hydrogels for cell immobilization. Biotechnol Bioeng 50, 357, 1996.
5. Lee, J., Cuddihy, M.J., and Kotov, N.A. Three-dimensional cell culture matrices: State of the art. Tissue Eng Part B Rev 14, 61, 2008.
6. Meli, L., Jordan, E.T., Clark, D.S., Linhardt, R.J., and Dordick, J.S. Influence of a three-dimensional, microarray environment on human Cell culture in drug screening systems. Biomaterials 33, 9087, 2012.
7. Geckil, H., Xu, F., Zhang, X., Moon, S., and Demirci, U. Engineering hydrogels as extracellular matrix mimics. Nanomedicine 5, 469, 2010.
8. Tibbitt, M.W., and Anseth, K.S. Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng 103, 655, 2009.
9. Mauney, J.R., Volloch, V., and Kaplan, D.L. Role of adult mesenchymal stem cells in bone tissue-engineering applications: Current status and future prospects. Tissue Eng 11, 787, 2005.
10. Kneser, U., Schaefer, D.J., Polykandriotis, E., and Horch, R.E. Tissue engineering of bone: The reconstructive surgeon's point of view. J Cell Mol Med 10, 7, 2006.
11. Street, J., Bao, M., DeGuzman, L., Bunting, S., Peale, F.V., Jr., Ferrara, N., et al. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci U S A 99, 9656, 2002.
12. Slaughter, B.V., Khurshid, S.S., Fisher, O.Z., Khademhosseini, A., and Peppas, N.A. Hydrogels in regenerative medicine. Adv Mater 21, 3307, 2009.
13. Albrecht, D.R., Underhill, G.H., Wassermann, T.B., Sah, R.L., and Bhatia, S.N. Probing the role of multicellular organization in three-dimensional microenvironments. Nat Methods 3, 369, 2006.
14. Nicodemus, G.D., and Bryant, S.J. Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue Eng Part B Rev 14, 149, 2008.
15. Lee, K.Y., and Mooney, D.J. Alginate: Properties and biomedical applications. Prog Polym Sci (Oxford) 37, 106, 2012.
16. Kong, H.J., Smith, M.K., and Mooney, D.J. Designing alginate hydrogels to maintain viability of immobilized cells. Biomaterials 24, 4023, 2003.
17. Rice, J.J., Martino, M.M., De Laporte, L., Tortelli, F., Briquez, P.S., and Hubbell, J.A. Engineering the regenerative microenvironment with biomaterials. Adv Healthc Mater 2, 57, 2013.
18. Kang, S.W., Cha, B.H., Park, H., Park, K.S., Lee, K.Y., and Lee, S.H. The Effect of conjugating RGD into 3D alginate hydrogels on adipogenic differentiation of human adipose-derived stromal cells. Macromol Biosci 11, 673, 2011.
19. Fonseca, K.B., Bidarra, S.J., Oliveira, M.J., Granja, P.L., and Barrias, C.C. Molecularly designed alginate hydrogels susceptible to local proteolysis as three-dimensional cellular microenvironments. Acta Biomater 7, 1674, 2011.
20. Zhou, H., and Xu, H.H.K. The fast release of stem cells from alginate-fibrin microbeads in injectable scaffolds for bone tissue engineering. Biomaterials 32, 7503, 2011.
21. Sun, J., Xiao, W., Tang, Y., Li, K., and Fan, H. Biomimetic interpenetrating polymer network hydrogels based on methacrylated alginate and collagen for 3D pre-osteoblast spreading and osteogenic differentiation. Soft Matter 8, 2398, 2012.
22. Haque, T., Chen, H., Ouyang, W., Martoni, C., Lawuyi, B., Urbanska, A.M., et al. In vitro study of alginatechitosan microcapsules: An alternative to liver cell transplants for the treatment of liver failure. Biotechnol Lett 27, 317, 2005.
23. Dahlmann, J., Krause, A., Möller, L., Kensah, G., Möwes, M., Diekmann, A., et al. Fully defined in situ cross-linkable alginate and hyaluronic acid hydrogels for myocardial tissue engineering. Biomaterials 34, 940, 2013.
24. Gelse, K., Pöschl, E., and Aigner, T. Collagens-structure, function, and biosynthesis. Adv Drug Deliv Rev 55, 1531, 2003.
25. Tan, H., Chu, C.R., Payne, K.A., and Marra, K.G. Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering. Biomaterials 30, 2499, 2009.
26. Huang, Y., Onyeri, S., Siewe, M., Moshfeghian, A., and Madihally, S.V. In vitro characterization of chitosan-gelatin scaffolds for tissue engineering. Biomaterials 26, 7616, 2005.
27. Bernhardt, A., Despang, F., Lode, A., Demmler, A., Hanke, T., and Gelinsky, M. Proliferation and osteogenic differentiation of human bone marrow stromal cells on alginate-gelatine-hydroxyapatite scaffolds with anisotropic pore structure. J Tissue Eng Regen Med 3, 54, 2009.
28. Almeida, P.F., and Almeida, A.J. Cross-linked alginategelatine beads: A new matrix for controlled release of pindolol. J Control Release 97, 431, 2004.
29. Liao, H., Zhang, H., and Chen, W. Differential physical, rheological, and biological properties of rapid in situ gelable hydrogels composed of oxidized alginate and gelatin derived from marine or porcine sources. J Mater Sci Mater Med 20, 1263, 2009.
30. Balakrishnan, B., and Jayakrishnan, A. Self-cross-linking biopolymers as injectable in situ forming biodegradable scaffolds. Biomaterials 26, 3941, 2005.
31. Balakrishnan, B., Mohanty, M., Umashankar, P.R., and Jayakrishnan, A. Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin. Biomaterials 26, 6335, 2005.
32. Nguyen, T.P., and Lee, B.T. Fabrication of oxidized alginate-gelatin-BCP hydrogels and evaluation of the microstructure, material properties and biocompatibility for bone tissue regeneration. J Biomater Appl 27, 311, 2012.
33. Augst, A.D., Kong, H.J., and Mooney, D.J. Alginate hydrogels as biomaterials. Macromol Biosci 6, 623, 2006.
34. Drury, J.L., and Mooney, D.J. Hydrogels for tissue engineering: Scaffold design variables and applications. Biomaterials 24, 4337, 2003.
35. Boanini, E., Rubini, K., Panzavolta, S., and Bigi, A. Chemicophysical characterization of gelatin films modified with oxidized alginate. Acta Biomater 6, 383, 2010.
36. Manju, S., Muraleedharan, C.V., Rajeev, A., Jayakrishnan, A., and Joseph, R. Evaluation of alginate dialdehyde crosslinked gelatin hydrogel as a biodegradable sealant for polyester vascular graft. J Biomed Mater Res Part B Appl Biomater 98B, 139, 2011.
37. Sakai, S., Yamaguchi, S., Takei, T., and Kawakami, K. Oxidized alginate-cross-linked alginate/gelatin hydrogel fibers for fabricating tubular constructs with layered smooth muscle cells and endothelial cells in collagen gels. Biomacromolecules 9, 2036, 2008.
38. Bouhadir, K.H., Lee, K.Y., Alsberg, E., Damm, K.L., Anderson, K.W., and Mooney, D.J. Degradation of partially oxidized alginate and its potential application for tissue engineering. Biotechnol Prog 17, 945, 2001.
39. Sarkar, B., Papageorgiou, D.G., Silva, R., Zehnder, T., Gul-E-Noor, F., Bertmer, M., et al. Fabrication of alginate gelatin crosslinked hydrogel microcapsules and evaluation of the microstructure and physio-chemical properties. J Mater Chem B 2, 1470, 2014.
40. Ye, J., Xiong, J., and Sun, R. The fluorescence property of Schiff's bases of carboxymethyl cellulose. Carbohydr Polym 88, 1420, 2012.
41. Issa, R.M., Khedr, A.M., and Rizk, H. 1H NMR, IR and UV/VIS spectroscopic studies of some schiff bases derived from 2-Aminobenzothiazole and 2-Amino-3-hydroxypyridine. J Chin Chem Soc (Taipei) 55, 875, 2008.
42. Bajpai, S.K., and Sharma, S. Investigation of swelling/ degradation behaviour of alginate beads crosslinked with Ca2 + and Ba2 + ions. React Funct Polym 59, 129, 2004.
43. Gomez, C.G., Rinaudo, M., and Villar, M.A. Oxidation of sodium alginate and characterization of the oxidized derivatives. Carbohydr Polym 67, 296, 2007.
44. Kristiansen, K.A., Tomren, H.B., and Christensen, B.E. Periodate oxidized alginates: Depolymerization kinetics. Carbohydr Polym 86, 1595, 2011.
45. Sobral, J.M., Caridade, S.G., Sousa, R.A., Mano, J.F., and Reis, R.L. Three-dimensional plotted scaffolds with controlled pore size gradients: Effect of scaffold geometry on mechanical performance and cell seeding efficiency. Acta Biomater 7, 1009, 2011.
46. Leal-Egaña, A., Dietrich-Braumann, U., Diáz-Cuenca, A., Nowicki, M., and Bader, A. Determination of pore size distribution at the cell-hydrogel interface. J Nanobiotechnol 9, 24, 2011.
47. Khattak, S.F., Spatara, M., Roberts, L., and Roberts, S.C. Application of colorimetric assays to assess viability, growth and metabolism of hydrogel-encapsulated cells. Biotechnol Lett 28, 1361, 2006.
48. Evangelista, M.B., Hsiong, S.X., Fernandes, R., Sampaio, P., Kong, H.J., Barrias, C.C., et al. Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix. Biomaterials 28, 3644, 2007.
49. Kong, H.J., Boontheekul, T., and Mooney, D.J. Quantifying the relation between adhesion ligand-receptor bond formation and cell phenotype. Proc Natl Acad Sci U S A 103, 18534, 2006.
50. Lee, J.W., Park, Y.J., Lee, S.J., Lee, S.K., and Lee, K.Y. The effect of spacer arm length of an adhesion ligand coupled to an alginate gel on the control of fibroblast phenotype. Biomaterials 31, 5545, 2010.
51. Hunt, N.C., Shelton, R.M., Henderson, D.J., and Grover, L.M. Calcium-Alginate hydrogel-encapsulated fibroblasts provide sustained release of vascular endothelial growth factor. Tissue Eng Part A 19, 905, 2013.
52. Bidarra, S.J., Barrias, C.C., Barbosa, M.A., Soares, R., and Granja, P.L. Immobilization of human mesenchymal stem cells within RGD-grafted alginate microspheres and assessment of their angiogenic potential. Biomacromolecules 11, 1956, 2010.
53. Keshaw, H., Forbes, A., and Day, R.M. Release of angiogenic growth factors from cells encapsulated in alginate beads with bioactive glass. Biomaterials 26, 4171, 2005.
54. Hunt, N.C., Smith, A.M., Gbureck, U., Shelton, R.M., and Grover, L.M. Encapsulation of fibroblasts causes accelerated alginate hydrogel degradation. Acta Biomater 6, 3649, 2010.
55. Yuan, Y., Tse, K.T., Sin, F.W.Y., Xue, B., Fan, H.H., and Xie, Y. Ex vivo amplification of human hematopoietic stem and progenitor cells in an alginate three-dimensional culture system. Int J Lab Hematol 33, 516, 2011.
56. Chayosumrit, M., Tuch, B., and Sidhu, K. Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm. Biomaterials 31, 505, 2010.
57. Huebsch, N., Arany, P.R., Mao, A.S., Shvartsman, D., Ali, O.A., Bencherif, S.A., et al. Harnessing traction-mediated manipulation of the cell/matrix interface to control stemcell fate. Nat Mater 9, 518, 2010.
58. Bidarra, S.J., Barrias, C.C., Fonseca, K.B., Barbosa, M.A., Soares, R.A., and Granja, P.L. Injectable in situ crosslinkable RGD-modified alginate matrix for endothelial cells delivery. Biomaterials 32, 7897, 2011.
59. Cai, K., Zhang, J., Deng, L.H., Yang, L., Hu, Y., Chen, C., et al. Physical and biological properties of a novel hydrogel composite based on oxidized alginate, gelatin and tricalcium phosphate for bone tissue engineering. Adv Eng Mater 9, 1082, 2007.
60. Detsch, R., Sarker, B., Grigore, A., and Boccaccini, A.R. Alginate and gelatine blending for bone cell printing and biofabrication. IASTED International Conference Biomedical Engineering Innsbruck. Austria: ACTA Press, 2013, pp. 451-455.