An activin A/BMP2 chimera, AB204, displays bone-healing properties superior to those of BMP2

Journal of Bone and Mineral Research

Volumn 29, Issue 9, 2014, Pages 1950-1959

  Yoon, Byung Hak ^a,b   Esquivies, Luis ^c   Ahn, Chihoon ^a   Gray, Peter C ^d   Ye, Sang Kyu ^b   Kwiatkowski, Witek ^a,c   Choe, Senyon ^a,c  

^a Songdo Global University Campus   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

AB204; ACTIVIN A BMP2 CHIMERA; BONE HEALING; CRITICAL SIZE DEFECT; OSTEOGENESIS

Indexed keywords

AB 204; ACTIVIN A; AMINO ACID; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; LIGAND; NOGGIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG; AB204; ACTIVIN; ACTIVIN RECEPTOR 1; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; HYBRID PROTEIN; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE DEVELOPMENT; CELL VIABILITY ASSAY; CHIMERA; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG POTENCY; FRACTURE HEALING; IN VITRO STUDY; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOBLAST; ANIMAL; BONE MINERALIZATION; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; PATHOLOGY; POINT MUTATION; SKULL; TIBIA; WOUND HEALING;

ACTIVIN RECEPTORS, TYPE I; ACTIVINS; ALKALINE PHOSPHATASE; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CELL LINE; HUMANS; MICE; OSTEOGENESIS; POINT MUTATION; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SKULL; TIBIA; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 84906351590     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2238     Document Type: Article

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