Enhancement of absorption and hepatoprotective potential through soya-phosphatidylcholine-andrographolide vesicular system

Journal of Liposome Research

Volumn 23, Issue 2, 2013, Pages 110-118

  Jain, Pushpendra Kumar ^a   Khurana, Navneet ^a   Pounikar, Yogesh ^a   Gajbhiye, Asmita ^a   Kharya, Murli Dhar ^a  

^a DR H S GOUR UNIVERSITY   (India)

Author keywords

Andrographis paniculata; Andrographolide; Carbon tetrachloride; Hepatoprotective activity; Herbosomes; Soy lecithin

Indexed keywords

ALANINE AMINOTRANSFERASE; ANDROGRAPHOLIDE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; PHOSPHATIDYLCHOLINE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANDROGRAPHIS PANICULATA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG SOLUBILITY; EX VIVO STUDY; HISTOPATHOLOGY; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIPID VESICLE; LIPOSOMAL DELIVERY; LIVER PROTECTION; LIVER TOXICITY; MALE; MELTING POINT; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SMALL INTESTINE; SOYBEAN; THIN LAYER CHROMATOGRAPHY; TREATMENT DURATION;

ANIMALS; BIOLOGICAL AVAILABILITY; DITERPENES; LIVER; MALE; PHOSPHATIDYLCHOLINES; RATS; RATS, WISTAR; SOYBEANS;

EID: 84878428577     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.3109/08982104.2012.753456     Document Type: Article

References (26)

1. Barthe L, Woodley J, Kenworthy S, Houin G. (1998). An improved everted gut sac as a simple and accurate technique to measure para-cellular transport across the small intestine. Eur J Drug Metab Pharmacokinet 23:313-23. (Pubitemid 28401125)
2. Bombardelli E. (1994). Phytosomes in functional cosmetics. Fitoterapia 65:320-7.
3. Bombardelli E, Curri SB, Della LR. (1989). Complexes between phospholipids and vegetal derivatives of biological interest. Fitoterapia 90:1-9.
4. Bombardelli E, Spelta M, Loggia DR, et al. (1991). Aging skin: protective effect of silymarin phytosome. Fitoterapia 62:115-22.
5. Caceres DD, Hancke JL, Burgos RA, Wikman GK. (1997). Prevention of common colds with Andrographis paniculata dried extract: a pilot double blind trial. Phytomedicine 4:101-4. (Pubitemid 127568217)
6. Caceres DD, Hancke JL, Burgos RA, et al. (1999). Use of visual analogue scale measurements (VAS) to assess the effectiveness of standardizing Andrographis paniculata extract SHA-10 in reducing the symptoms of common cold. A randomized double blind-placebo study. Phytomedicine 6:217-23. (Pubitemid 129633193)
7. Calabrese C, Berman S, Babish J, et al. (2000). A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother Res 14:333-8. (Pubitemid 30655517)
8. Coon JT, Ernst E. (2004). Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med 70:293-8. (Pubitemid 38594598)
9. Das SK, Vasudevan DM. (2006). Effect of lecithin in the treatment of ethanol mediated free radical induced hepatotoxicity. Indian J Clin Biochem 21:62-9.
10. Deng WL. (1978). Preliminary studies on the pharmacology of the Andrographis product dihydroandrographolide sodium succinate. Newslett Chin Herb Med 8:26-8.
11. Gupta A, Ashawat MS, Saraf S, Saraf S. (2007). Phytosome: a novel approach towards functional cosmetics. J Plant Sci 2:644-9. (Pubitemid 47435469)
12. Humanson GL. (1962). Animal tissue technique. San Francisco: W.H. Freeman Publisher and Distributor.
13. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-75.
14. Madav HC, Tripathi T, Mishra SK. (1995). Analgesic, antipyretic, and antiulcerogenic effects of andrographolide. Indian J Pharmaceut Sci 57:121-5.
15. Maiti K, Mukherjee K, Gantait A, et al. (2005). Enhanced therapeutic benefit of quercetin-phospholipid complex in carbon tetrachloride induced acute liver injury in rats: a comparative study. Iran J Pharmacol Therapeut 4:84-90.
16. Maiti K, Mukherjee K, Gantait A, et al. (2006). Enhanced therapeutic potential of naringenin-phospholipid complex in rats. J Pharm Pharmacol 58:1227-33. (Pubitemid 44329104)
17. Panossian A, Hovhannisyan A, Manikonyan G, et al. (2000). Pharmacokinetic and oral bioavailability of andrographolide from Andrographis paniculata fixed combination Kan Jang in rats and human. Phytomedicine 7:351-64.
18. Puri A, Saxena R, Saxena RP, Saxena KC. (1993). Immunostimulant agents from Andrographis paniculata. J Nat Prod 56:995-9. (Pubitemid 23222198)
19. Raj PV, Nitesh K, Chandrashekhar HR, et al. (2010). Effect of lecithin and silymarin on d-galactosamine induced toxicity in isolated hepa-tocytes and rats. Indian J Clin Biochem 25:169-74.
20. Rajagopal S, Kumar RA, Deevi DS, et al. (2003). Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata. J Exp Therapeut Oncol 3:147-58. (Pubitemid 37153001)
21. Sharma A, Gupta NK, Dixit VK. (2010). Complexation with phospha-tidyl choline as a strategy for absorption enhancement of boswellic acid. Drug Deliv 17:587-95.
22. Shen Y, Chen C, Chiou W. (2002). Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effect. Br J Pharmacol 135:399-406. (Pubitemid 34151172)
23. Shukla B, Visen PK, Patnaik GK, Dhawan BN. (1992). Choleretic effect of andrographolide in rats and guinea pigs. Planta Med 58:146-9.
24. Sinha J, Mukhopadhyay S, Das N, Basu MK. (2000). Targeting of liposomal andrographolide to L. donovani-infected macrophages in vivo. Drug Deliv 7:209-13. (Pubitemid 32057552)
25. Yanyu X, Yunmei S, Zhipeng C, et al. (2006). The preparation of silybin-phospholipid complex and the study on its pharmacokinetics in rats. Int J Pharm 307:77-82. (Pubitemid 41773254)
26. Yu BC, Hung CR, Chen WC, Cheng JT. (2003). Antihyperglycemic effect of andrographolide in streptozotocin-induced diabetic rats. Planta Med 69:1075-9.