Promotion of remyelination by adipose mesenchymal stem cell transplantation in a cuprizone model of multiple sclerosis

Cell Journal

Volumn 15, Issue 2, 2013, Pages 142-151

  Hedayatpour, Azim ^a   Ragerdi, Iraj ^a   Pasbakhsh, Parichehr ^a   Kafami, Laya ^b   Atlasi, Nader ^a   Mahabadi, Vahid Pirhajati ^a   Ghasemi, Soudabeh ^a   Mahmoudi, Reza ^c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ALBORZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c YASUJ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Adipose; Demyelination; Mesenchymal stem cells; Transplantation

Indexed keywords

CUPRIZONE;

ADIPOSE MESENCHYMAL STEM CELL; ADIPOSE MESENCHYMAL STEM CELL TRANSPLANTATION; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL HOMING; CONTROLLED STUDY; CORPUS CALLOSUM; EXPERIMENTAL STUDY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; REMYELINIZATION; TRANSMISSION ELECTRON MICROSCOPY;

EID: 84906303624     PISSN: 22285806     EISSN: 22285814     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Einstein O, Friedman-Levi Y, Grigoriadis N, Ben-Hur T.Transplanted neural precursors enhance host brain-derived myelin regeneration. J Neurosci. 2009; 29(50): 15694-15702.
2. Aharonowiz M, Einstein O, Fainstein N, Lassmann H, Reubinoff B, Ben-Hur T. Neuroprotective effect of transplanted human embryonic stem cell-derived neural precursors in an animal model of multiple sclerosis. PLoS One. 2008; 3(9): e3145.
3. Grigoriadis N, Lourbopoulos A, Lagoudaki R, Frischer JM, Polyzoidou E, Touloumi O, et al. Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis.Exp Neurol. 2011; 230(1): 78-89.
4. Cao F, van der Bogt KE, Sadrzadeh A, Xie X, Sheikh AY, et al. Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation. Stem Cells Dev. 2007; 16(6): 883-891.
5. Constantin G, Marconi S, Rossi B, Angiari S, Calderan L, Anghileri E, et al. Adipose-derived mesenchymal stem cells ameliorate chronic experimental autoimmune encephalomyelitis. Stem Cells. 2009; 27(10): 2624-2635.
6. Zaminy A, Ragerdi Kashani I, Barbarestani M, Hedayatpour A, Mahmoudi R, Vardasbi S, et al. Melatonin influences the proliferative and differentiative activity of rat adipoe-derived stem cells. Yakhteh. 2008; 10(1): 25-32.
7. Fraser JK, Wulur I, Alfonso Z, Hedrick MH. Fat tissue: an underappreciated source of stem cells for biotechnology. Trends Biotechnol. 2006; 24(4): 150-154.
8. De Ugarte DA, Alfonso Z, Zuk PA, Elbarbary A, Zhu M, Ashjian P, et al. Differential expression of stem cell mobilization-associated molecules on multi-lineage cells from adipose tissue and bone marrow. Immunol Lett. 2003; 89(2-3): 267-270.
9. Jackson JS, Golding JP, Chapon C, Jones WA, Bhakoo KK. Homing of stem cells to sites of inflammatory brain injury after intracerebral and intravenous administration: a longitudinal imaging study. Stem Cell Res Ther. 2010; 1(2): 17.
10. Crocker SJ, Bajpai R, Moore CS, Frausto RF, Brown GD, Pagarigan RR, et al. Intravenous administration of human embryonic stem cell-derived neural precursor cells attenuates cuprizone-induced central nervous system (CNS) demyelination. Neuropathol Appl Neurobiol. 2011; 37(6): 643-653.
11. Matsushima GK, MorellP. Theneurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system. Brain Pathol. 2001; 11(1): 107-116.
12. Short MA, Campanale N, Litwak S, Bernard CC. Quantitative and phenotypic analysis of bone marrow-derived cells in the intact and inflamed central nervous system. Cell Adh Migr. 2011; 5(5): 373-381.
13. Stidworthy MF, Genoud S, Suter U, Mantei N, Franklin RJ. Quantifying the earlystages of remyelination following cuprizone-induceddemyelination. Brain Pathol. 2003; 13(3): 329-339.
14. Sospedra M, Martin R. Immunology of multiple sclerosis. Annu Rev Immunol. 2005; 23: 683-747.
15. Perini P, Calabrese M, Rinaldi L, Gallo P. The safety profile of cyclophosphamidein multiple sclerosis therapy. Expert Opin Drug Saf. 2007; 6(2): 183-190.
16. Hasan KM. Walimuni IS, Abid H, Datta S, Wolinsky JS, Narayana PA. Human brain atlas-based multimodal MRI analysis of volumetry, diffusimetry, relaxometry and lesion distribution in multiple sclerosis patients and healthy adult controls: implications for understanding the pathogenesis of multiple sclerosis and consolidation of quantitative MRI results in MS. J Neurol Sci. 2012; 313 (2): 99-109.
17. Hansen B, Oturai AB, Harbo HF, Celius EG, Nissen KK, Laska MJ, et al. Genetic association of multiple sclerosis with the marker rs391745 near the endogenous retroviral locus HERV-Fc1: analysis of disease subtypes. PLoS One. 2011; 6(10): e26438.
18. Ramagopalan SV, Dobson R, Meier UC, Giovannoni G. Multiple sclerosis: risk factors, prodromes, and potential causal pathways. Lancet Neurol. 2010, 9: 727-739.
19. Bai L, Lennon DP, Eaton V, Maier K, Caplan AI, Miller SD, et al. Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis. Glia. 2009; 57(11): 1192-1203.
20. Gerdoni E, Gallo B, Casazza S, Musio S, Bonanni I, Pedemonte E, et al. Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis. Ann Neurol. 2007; 61(3): 219-227.
21. Inoue M, Honmou O, Oka S, Houkin K, Hashi K, Kocsis JD. Comparative analysis of remyelinating potential of focal and intravenous administration of autologous bone marrow cells into the rat demyelinated spinal cord. Glia. 2003; 44(2): 111-118.
22. Denic A, Johnson AJ, Bieber AJ, Warrington AE, Rodriguez M, Pirko I. The relevance of animal models in multiple sclerosis research. Pathophysiology. 2011; 18(1): 21-29.
23. Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E, Stornaiuolo A, Cossu G, et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science. 1998; 279(5356): 1528-1530.
24. Kim JS. Cytokines and adhesion molecules in stroke and related diseases. J Neurol Sci. 1996; 137(2): 69-78.
25. Ho IA, Chan KY, Ng WH, Guo CM, Hui KM, Cheang P, et al. Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma. Stem Cells. 2009; 27(6): 1366-1375.
26. Haraldsen G, Kvale D, Lien B, Farstad IN, Brandtzaeg P. Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J Immunol. 1996; 156(7): 2558-2565.
27. Shi E, Kazui T, Jiang X, Washiyama N, Yamashita K, Terada H, et al. Therapeutic benefit of injection of marrow stromal cells on ischemia-injured spinal cord. Ann Thorac Surg. 2007; 83(4): 1484-1490.
28. Chopp M, Li Y. Treatment of neural injury with marrow stromal cells. Lancet Neurol. 2002; 1(2): 92-100.
29. Eglitis MA, Mezey E. Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice. Proc Natl Acad Sci USA. 1997;94(8): 4080-4085
30. Tambuyzer BR, Bergwerf I, De Vocht N, Reekmans K, Daans J, Jorens PG, et al. Allogeneic stromal cell implantation in brain tissue leads to robust microglial activation. Immunol Cell Biol. 2009; 87(4): 267-273.
31. Bergwerf I, Tambuyzer B, De Vocht N, Reekmans K, Praet J, Daans J, et al. Recognition of cellular implants by the brain's innate immune system. Immunol Cell Biol. 2011; 89(4): 511-516.
32. Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC. A crucialrole for interleukin (IL)-1 in the induction of IL-17-producingTcells that mediateautoimmuneencephalomyelitis. J Exp Med. 2006; 203(7): 1685-1691.
33. Miljkovic D, Momcilovic M, Stojanovic I, Stosic-Grujicic S, Ramic Z, Mostarica-Stojkovic M. Astrocytes stimulate interleukin-17 and interferon-gamma production in vitro. J Neurosci Res. 2007; 85(16): 3598-3606.