Phospholipase D2 downregulation induces cellular senescence through a reactive oxygen species-p53-p21Cip1/WAF1 pathway

FEBS Letters

Volumn 588, Issue 17, 2014, Pages 3251-3258

  Lee, Young Hoon ^a   Bae, Young Seuk ^a  

^a Kyungpook National University   (South Korea)

Author keywords

p53; Phospholipase D2; Protein kinase CK2; Reactive oxygen species; Senescence

Indexed keywords

ACETYLCYSTEINE; APOCYNIN; CASEIN KINASE II; CYCLIN DEPENDENT KINASE INHIBITOR 1; PHOSPHOLIPASE D2; PROTEIN P22; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ARTICLE; CELL AGING; CELL DIVISION; CELL PROLIFERATION; COLON CANCER; DOWN REGULATION; ENZYME REPRESSION; HCT116 CELL LINE; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SUBUNIT; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WILD TYPE;

P21(CIP1/WAF1); P53; PHOSPHOLIPASE D2; PROTEIN KINASE CK2; REACTIVE OXYGEN SPECIES; SENESCENCE;

BASE SEQUENCE; CASEIN KINASE II; CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOWN-REGULATION; HCT116 CELLS; HUMANS; INTRACELLULAR SPACE; NADPH OXIDASE; PHOSPHOLIPASE D; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84906276622     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.07.009     Document Type: Article

References (35)

1. M. Liscovitch, M. Czarny, G. Fiucci, and X. Tang Phospholipase D: molecular and cell biology of a novel gene family Biochem. J. 345 2000 401 415
2. P.E. Selvy, R.R. Lavieri, C.W. Lindsley, and H.A. Brown Phospholipase D: enzymology, functionality, and chemical modulation Chem. Rev. 111 2011 6064 6119
3. S.A. Rudge, and M.J.O. Wakelam Inter-regulatory dynamics of phospholipase D and the actin cytoskeleton Biochim. Biophys. Acta 1791 2009 856 861
4. J. Gomez-Cambronero New concepts in phospholipase D signaling in inflammation and cancer ScientificWorldJournal 10 2010 1356 1369
5. A. Kallioniemi, O.P. Kallioniemi, D. Sudar, D. Rutovitz, J.W. Gray, F. Waldman, and D. Pinkel Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors Science 258 1992 818 821
6. F. Courjal, and C. Theillet Comparative genomic hybridization analysis of breast tumors with predetermined profiles of DNA amplification Cancer Res. 57 1997 4368 4377
7. T. Kuukasjarvi, R. Karhu, M. Tanner, M. Kahkonen, A. Schaffer, N. Nupponen, S. Pennanen, A. Kallioniemi, O. Kallioniemi, and J. Isola Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer Cancer Res. 57 1997 1597 1604
8. S. Goldstein Replicative senescence: the human fibroblast comes of age Science 249 1990 1129 1133
9. 2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication Biochem. J. 332 1998 43 50
10. INK4a Cell 88 1997 593 602
11. INK4a enrichment and the premature senescence of normal fibroblasts Oncogene 16 1998 1113 1123
12. CIP1/WAF1 gene in normal diploid human fibroblasts Science 277 1997 831 834
13. G.P. Dimri, X. Lee, G. Basile, M. Acosta, G. Scott, C. Roskelley, E.E. Medrano, M. Linskens, I. Rubelj, O. Pereira-Smith, M. Peacocke, and J. Campisi A biomarker that identifies senescent human cells in culture and in aging skin in vivo Proc. Natl. Acad. Sci. U.S.A. 92 1995 9363 9367
14. M.E. Venable, G.C. Blobe, and L.M. Obeid Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence J. Biol. Chem. 269 1994 26040 26044
15. M.E. Venable, and L.M. Obeid Phospholipase D in cellular senescence Biochim. Biophys. Acta 1439 1999 291 298
16. L.M. Webb, A.T. Arnholt, and M.E. Venable Phospholipase D modulation by ceramide in senescence Mol. Cell. Biochem. 337 2010 153 158
17. Y.H. Lee, J.H. Yuk, K.H. Park, and Y.S. Bae Coumestrol induces senescence through protein kinase CKII inhibition-mediated reactive oxygen species production in human breast cancer and colon cancer cells Food Chem. 141 2013 381 388
18. T. Waldman, K.W. Kinzler, and B. Vogelstein P21 is necessary for the p53-mediated G1 arrest in human cancer cells Cancer Res. 55 1995 5187 5190
19. 2 arrest after DNA damage Science 282 1998 1497 1501
20. H.F. Horn, and K.H. Vousden Coping with stress: multiple ways to activate p53 Oncogene 26 2007 1306 1316
21. W.O. Carter, P.K. Narayanan, and J.P. Robinson Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells J. Leukoc. Biol. 55 1994 253 258
22. V.P. Bindokas, J. Jordan, C.C. Lee, and R.J. Miller Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine J. Neurosci. 16 1996 1324 1336
23. E.C. Chan, F. Jiang, H.M. Peshavariya, and G.J. Dusting Regulation of cell proliferation by NADPH oxidase-mediated signaling: potential roles in tissue repair, regenerative medicine and tissue engineering Pharmacol. Ther. 122 2009 97 108
24. R.K. Ambasta, P. Kumar, K.K. Griendling, H.H. Schmidt, R. Busse, and R.P. Brandes Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase J. Biol. Chem. 279 2004 45935 45941
25. P. Mukhopadhyay, M. Rajesh, K. Yoshihiro, G. Haskó, and P. Pacher Simple quantitative detection of mitochondrial superoxide production in live cells Biochem. Biophys. Res. Commun. 358 2007 203 208
26. S.W. Ryu, J.H. Woo, Y.H. Kim, Y.S. Lee, J.W. Park, and Y.S. Bae Down-regulation of protein kinase CKII is associated with cellular senescence FEBS Lett. 580 2006 988 994
27. Cip1/WAF1 pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells Mol. Cells 28 2009 489 494
28. S.M. Jeon, S.J. Lee, T.K. Kwon, K. Kim, and Y.S. Bae NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells FEBS Lett. 584 2010 3137 3142
29. B.H. Ahn, G. Min, Y.S. Bae, Y.S. Bae, and D.S. Min Phospholipase D is activated and phosphorylated by casein kinase-II in human U87 astroglioma cells Exp. Mol. Med. 38 2006 55 62
30. M. Ruzzene, and L.A. Pinna Addiction to protein kinase CK2: a common denominator of diverse cancer cells? Biochim. Biophys. Acta 1804 2010 499 504
31. R.A. Faust, M. Gapany, P. Tristani, A. Davis, G.L. Adams, and K. Ahmed Elevated protein kinase CK2 activity in chromatin of head and neck tumors: association with malignant transformation Cancer Lett. 101 1996 31 35
32. E. Landesman-Bollag, R. Romieu-Mourez, D.H. Song, G.E. Sonenshein, R.D. Cardiff, and D.C. Seldin Protein kinase CK2 in mammary gland tumorigenesis Oncogene 20 2001 3247 3257
33. K.Y. Lin, C. Tai, J.C. Hsu, C.F. Li, C.L. Fang, H.C. Lai, Y.C. Hseu, Y.F. Lin, and Y.H. Uen Overexpression of nuclear protein kinase CK2 α catalytic subunit (CK2α) as a poor prognosticator in human colorectal cancer PLoS ONE 6 2011 e17193
34. A. Krippner-Heidenreich, R. Talanian, V.R. Sekul, R. Kraft, H. Thole, H. Ottleben, and B. Lüscher Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1 Biochem. J. 358 2001 705 715
35. J.S. Sanghera, L.A. Charlton, H.B. Paddon, and S.L. Pelech Purification and characterization of echinoderm casein kinase II. Regulation by protein kinase C Biochem. J. 283 1992 829 837