NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells

FEBS Letters

Volumn 584, Issue 14, 2010, Pages 3137-3142

  Jeon, Seon Min ^a   Lee, Sung Jin ^b   Kwon, Taeg Kyu ^c   Kim, Kyung Jin ^d   Bae, Young Seuk ^a  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Keimyung University   (South Korea)

^d Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

NADPH oxidase; P53 activation; Protein kinase CKII; Senescence; Superoxide anion

Indexed keywords

ACETYLCYSTEINE; APOCYNIN; CASEIN KINASE II; CASEIN KINASE IIALPHA; CELL MARKER; HYDROGEN PEROXIDE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN P22; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; SUPEROXIDE; UNCLASSIFIED DRUG; ACETOPHENONE DERIVATIVE; ANTIOXIDANT;

ARTICLE; CANCER CELL; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SENESCENCE; AGING; CELL AGING; COLON TUMOR; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MITOCHONDRION; PHYSIOLOGY; TUMOR SUPPRESSOR GENE;

ACETOPHENONES; ACETYLCYSTEINE; AGING; ANTIOXIDANTS; CASEIN KINASE II; CELL AGING; COLONIC NEOPLASMS; DOWN-REGULATION; GENES, P53; HCT116 CELLS; HUMANS; HYDROGEN PEROXIDE; MITOCHONDRIA; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SUPEROXIDES;

EID: 77954173903     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.05.054     Document Type: Article

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