Involvement of ERCC1 in the pathogenesis of osteoarthritis through the modulation of apoptosis and cellular senescence

Journal of Orthopaedic Research

Volumn 32, Issue 10, 2014, Pages 1326-1332

  Takayama, Koji ^a,b   Kawakami, Yohei ^a,b   Lee, Sahnghoon ^a,b   Greco, Nick ^a,b   Lavasani, Mitra ^a,b   Mifune, Yutaka ^a,b   Cummins, James H ^a,b   Yurube, Takashi ^b   Kuroda, Ryosuke ^c   Kurosaka, Masahiro ^c   Fu, Freddie H ^b   Huard, Johnny ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

apoptosis; ERCC1; interleukin (IL) 1 ; osteoarthritis; senescence

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE 3; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN P16; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARTILAGE CELL; CATABOLISM; CELL AGING; CELL COUNT; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; IN VITRO STUDY; KNEE OSTEOARTHRITIS; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENESCENCE;

APOPTOSIS; ERCC1; INTERLEUKIN (IL)-1Β; OSTEOARTHRITIS; SENESCENCE;

ANIMALS; APOPTOSIS; CARTILAGE, ARTICULAR; CELL AGING; CHONDROCYTES; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ENDONUCLEASES; HUMANS; MICE; MICE, INBRED C57BL; OSTEOARTHRITIS;

EID: 84906265329     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22656     Document Type: Article

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