메뉴 건너뛰기




Volumn 69, Issue 9, 2014, Pages 1049-1059

Propeptide-mediated inhibition of myostatin increases muscle mass through inhibiting proteolytic pathways in aged mice

Author keywords

Aging; Mouse; Muscle; Myostatin; Sarcopenia.

Indexed keywords

MUSCLE PROTEIN; MYOSTATIN; PEPTIDE;

EID: 84906264366     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt170     Document Type: Article
Times cited : (20)

References (50)
  • 1
    • 0018630347 scopus 로고
    • Metabolic functions of skeletal muscles of man, mammals, birds and fishes: A review
    • Spargo E, Pratt OE, Daniel PM. Metabolic functions of skeletal muscles of man, mammals, birds and fishes: A review. J R Soc Med. 1979;72:921-925
    • (1979) J R Soc Med , vol.72 , pp. 921-925
    • Spargo, E.1    Pratt, O.E.2    Daniel, P.M.3
  • 2
    • 77953870112 scopus 로고    scopus 로고
    • European working group on sarcopenia in older people sarcopenia: European consensus on Definition and diagnosis: Report of the european working group on sarcopenia in older people
    • Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al.; European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on Definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39:412-423
    • (2010) Age Ageing , vol.39 , pp. 412-423
    • Cruz-Jentoft, A.J.1    Baeyens, J.P.2    Bauer, J.M.3
  • 3
    • 0025691113 scopus 로고
    • Skeletal muscle weakness and fatigue in old age: Underlying mechanisms
    • Faulkner JA, Brooks SV, Zerba E. Skeletal muscle weakness and fatigue in old age: Underlying mechanisms. Annu Rev Gerontol Geriatr. 1990;10:147-166
    • (1990) Annu Rev Gerontol Geriatr , vol.10 , pp. 147-166
    • Faulkner, J.A.1    Brooks, S.V.2    Zerba, E.3
  • 4
    • 0028849894 scopus 로고
    • Muscle atrophy and weakness with aging: Contraction-induced injury as an underlying mechanism
    • Spec No
    • Faulkner JA, Brooks SV, Zerba E. Muscle atrophy and weakness with aging: Contraction-induced injury as an underlying mechanism. J Gerontol A Biol Sci Med Sci. 1995;50 Spec No:124-129
    • (1995) J Gerontol A Biol Sci Med Sci , vol.50 , pp. 124-129
    • Faulkner, J.A.1    Brooks, S.V.2    Zerba, E.3
  • 5
    • 0023391947 scopus 로고
    • Changes in fibre type, number and diameter in Developing and ageing skeletal muscle
    • Alnaqeeb MA, Goldspink G. Changes in fibre type, number and diameter in Developing and ageing skeletal muscle. J Anat. 1987;153:31-45
    • (1987) J Anat , vol.153 , pp. 31-45
    • Alnaqeeb, M.A.1    Goldspink, G.2
  • 6
    • 0024316082 scopus 로고
    • Accumulation of collagen and altered fiber-Type ratios as indicators of abnormal muscle gene expression in the mdx dystrophic mouse
    • Marshall PA, Williams PE, Goldspink G. Accumulation of collagen and altered fiber-Type ratios as indicators of abnormal muscle gene expression in the mdx dystrophic mouse. Muscle Nerve. 1989;12:528-537
    • (1989) Muscle Nerve , vol.12 , pp. 528-537
    • Marshall, P.A.1    Williams, P.E.2    Goldspink, G.3
  • 7
    • 84925970732 scopus 로고    scopus 로고
    • Sarcopenia: Prevalence, mechanisms, and functional consequences
    • Berger MJ, Doherty TJ. Sarcopenia: Prevalence, mechanisms, and functional consequences. Interdiscip Top Gerontol. 2010;37:94-114
    • (2010) Interdiscip Top Gerontol , vol.37 , pp. 94-114
    • Berger, M.J.1    Doherty, T.J.2
  • 10
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature. 1997;387:83-90
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 11
    • 0030840359 scopus 로고    scopus 로고
    • Double muscling in cattle due to mutations in the myostatin gene
    • McPherron AC, Lee SJ. Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci USA. 1997;94:12457-12461
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12457-12461
    • McPherron, A.C.1    Lee, S.J.2
  • 12
    • 2942735123 scopus 로고    scopus 로고
    • Myostatin mutation associated with gross muscle hypertrophy in a child
    • Schuelke M, Wagner KR, Stolz LE, et al. Myostatin mutation associated with gross muscle hypertrophy in a child. N Engl J Med. 2004;350:2682-2688
    • (2004) N Engl J Med , vol.350 , pp. 2682-2688
    • Schuelke, M.1    Wagner, K.R.2    Stolz, L.E.3
  • 13
    • 33745577150 scopus 로고    scopus 로고
    • A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
    • Clop A, Marcq F, Takeda H, et al. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat Genet. 2006;38:813-818
    • (2006) Nat Genet , vol.38 , pp. 813-818
    • Clop, A.1    Marcq, F.2    Takeda, H.3
  • 14
    • 32944469015 scopus 로고    scopus 로고
    • The role of myostatin and bone morphogenetic proteins in muscular disorders
    • Tsuchida K. The role of myostatin and bone morphogenetic proteins in muscular disorders. Expert Opin Biol Ther. 2006;6:147-154
    • (2006) Expert Opin Biol Ther , vol.6 , pp. 147-154
    • Tsuchida, K.1
  • 16
    • 0037165983 scopus 로고    scopus 로고
    • Induction of cachexia in mice by systemically administered myostatin
    • Zimmers TA, Davies MV, Koniaris LG, et al. Induction of cachexia in mice by systemically administered myostatin. Science. 2002;296:1486-1488
    • (2002) Science , vol.296 , pp. 1486-1488
    • Zimmers, T.A.1    Davies, M.V.2    Koniaris, L.G.3
  • 17
    • 14644435182 scopus 로고    scopus 로고
    • The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis
    • Matsakas A, Diel P. The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis. Int J Sports Med. 2005;26:83-89
    • (2005) Int J Sports Med , vol.26 , pp. 83-89
    • Matsakas, A.1    Diel, P.2
  • 18
    • 9144243683 scopus 로고    scopus 로고
    • Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases
    • Wolfman NM, McPherron AC, Pappano WN, et al. Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases. Proc Natl Acad Sci USA. 2003;100:15842-15846
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15842-15846
    • Wolfman, N.M.1    McPherron, A.C.2    Pappano, W.N.3
  • 19
    • 0037174939 scopus 로고    scopus 로고
    • The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum
    • Hill JJ, Davies MV, Pearson AA, et al. The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum. J Biol Chem. 2002;277:40735-40741
    • (2002) J Biol Chem , vol.277 , pp. 40735-40741
    • Hill, J.J.1    Davies, M.V.2    Pearson, A.A.3
  • 20
    • 67649668906 scopus 로고    scopus 로고
    • Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice
    • Matsakas A, Foster K, Otto A, et al. Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice. Neuromuscul Disord. 2009;19:489-499
    • (2009) Neuromuscul Disord , vol.19 , pp. 489-499
    • Matsakas, A.1    Foster, K.2    Otto, A.3
  • 21
    • 33846902022 scopus 로고    scopus 로고
    • Lack of myostatin results in excessive muscle growth but impaired force generation
    • Amthor H, Macharia R, Navarrete R, et al. Lack of myostatin results in excessive muscle growth but impaired force generation. Proc Natl Acad Sci USA. 2007;104:1835-1840
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1835-1840
    • Amthor, H.1    Macharia, R.2    Navarrete, R.3
  • 22
    • 13044265837 scopus 로고    scopus 로고
    • Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting
    • Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, et al. Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting. Proc Natl Acad Sci USA. 1998;95:14938-14943
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14938-14943
    • Gonzalez-Cadavid, N.F.1    Taylor, W.E.2    Yarasheski, K.3
  • 23
    • 84861771804 scopus 로고    scopus 로고
    • Myostatin is associated with age-related human muscle stem cell dysfunction
    • McKay BR, Ogborn DI, Bellamy LM, Tarnopolsky MA, Parise G. Myostatin is associated with age-related human muscle stem cell dysfunction. FASEB J. 2012;26:2509-2521
    • (2012) FASEB J , vol.26 , pp. 2509-2521
    • McKay, B.R.1    Ogborn, D.I.2    Bellamy, L.M.3    Tarnopolsky, M.A.4    Parise, G.5
  • 24
    • 0036752685 scopus 로고    scopus 로고
    • Development of multiple cloning site cis-vectors for recombinant adeno-Associated virus production
    • 672, 674, 676-672, 674, 678
    • Yue Y, Dongsheng D. Development of multiple cloning site cis-vectors for recombinant adeno-Associated virus production. BioTechniques. 2002;33:672, 674, 676-672, 674, 678
    • (2002) BioTechniques , vol.33
    • Yue, Y.1    Dongsheng, D.2
  • 25
    • 84355162304 scopus 로고    scopus 로고
    • Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse
    • Matsakas A, Macharia R, Otto A, et al. Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse. Exp Physiol. 2012;97:125-140
    • (2012) Exp Physiol , vol.97 , pp. 125-140
    • Matsakas, A.1    Macharia, R.2    Otto, A.3
  • 26
    • 84860477251 scopus 로고    scopus 로고
    • Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice
    • Elashry MI, Collins-Hooper H, Vaiyapuri S, Patel K. Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice. J Anat. 2012;220:603-611
    • (2012) J Anat , vol.220 , pp. 603-611
    • Elashry, M.I.1    Collins-Hooper, H.2    Vaiyapuri, S.3    Patel, K.4
  • 27
    • 11144356337 scopus 로고    scopus 로고
    • Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
    • Sandri M, Sandri C, Gilbert A, et al. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell. 2004;117:399-412
    • (2004) Cell , vol.117 , pp. 399-412
    • Sandri, M.1    Sandri, C.2    Gilbert, A.3
  • 28
    • 84864882073 scopus 로고    scopus 로고
    • FOXOphagy path to inducing stress resistance and cell survival
    • Sandri M. FOXOphagy path to inducing stress resistance and cell survival. Nat Cell Biol. 2012;14:786-788
    • (2012) Nat Cell Biol , vol.14 , pp. 786-788
    • Sandri, M.1
  • 29
    • 35848930800 scopus 로고    scopus 로고
    • Regulation of mitochondrial integrity, autophagy and cell survival by bnip3
    • Tracy K, Macleod KF. Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3. Autophagy. 2007;3:616-619
    • (2007) Autophagy , vol.3 , pp. 616-619
    • Tracy, K.1    Macleod, K.F.2
  • 30
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature. 1999;402:672-676
    • (1999) Nature , vol.402 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3
  • 32
    • 0034676037 scopus 로고    scopus 로고
    • The reversible modification regulates the membrane-binding state of apg8/aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
    • Kirisako T, Ichimura Y, Okada H, et al. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol. 2000;151:263-276
    • (2000) J Cell Biol , vol.151 , pp. 263-276
    • Kirisako, T.1    Ichimura, Y.2    Okada, H.3
  • 33
    • 77955956764 scopus 로고    scopus 로고
    • Impaired turnover of autophagolysosomes in cathepsin L deficiency
    • Dennemärker J, Lohmüller T, Müller S, et al. Impaired turnover of autophagolysosomes in cathepsin L deficiency. Biol Chem. 2010;391:913-922
    • (2010) Biol Chem , vol.391 , pp. 913-922
    • Dennemärker, J.1    Lohmüller, T.2    Müller, S.3
  • 34
    • 77952576359 scopus 로고    scopus 로고
    • Negative regulation of Vps34 by Cdk mediated phosphorylation
    • Furuya T, Kim M, Lipinski M, et al. Negative regulation of Vps34 by Cdk mediated phosphorylation. Mol Cell. 2010;38:500-511
    • (2010) Mol Cell , vol.38 , pp. 500-511
    • Furuya, T.1    Kim, M.2    Lipinski, M.3
  • 36
    • 79955005054 scopus 로고    scopus 로고
    • Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation
    • Uddin MN, Ito S, Nishio N, Suganya T, Isobe K. Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation. Biochem Biophys Res Commun. 2011;407:692-698
    • (2011) Biochem Biophys Res Commun , vol.407 , pp. 692-698
    • Uddin, M.N.1    Ito, S.2    Nishio, N.3    Suganya, T.4    Isobe, K.5
  • 37
    • 0024674960 scopus 로고
    • Protozoa as precursors of metazoa: German cell theory and its critics at the turn of the century
    • Richmond ML. Protozoa as precursors of Metazoa: German cell theory and its critics at the turn of the century. J Hist Biol. 1989;22:243-276
    • (1989) J Hist Biol , vol.22 , pp. 243-276
    • Richmond, M.L.1
  • 38
    • 41149152962 scopus 로고    scopus 로고
    • Myostatin propeptide gene delivery by adenoassociated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice
    • Qiao C, Li J, Jiang J, et al. Myostatin propeptide gene delivery by adenoassociated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice. Hum Gene Ther. 2008;19:241-254
    • (2008) Hum Gene Ther , vol.19 , pp. 241-254
    • Qiao, C.1    Li, J.2    Jiang, J.3
  • 39
    • 47949097215 scopus 로고    scopus 로고
    • Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
    • Carlson ME, Hsu M, Conboy IM. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature. 2008;454:528-532
    • (2008) Nature , vol.454 , pp. 528-532
    • Carlson, M.E.1    Hsu, M.2    Conboy, I.M.3
  • 40
    • 33646357762 scopus 로고    scopus 로고
    • Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy
    • Haddad F, Adams GR. Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy. J Appl Physiol. 2006;100:1188-1203
    • (2006) J Appl Physiol , vol.100 , pp. 1188-1203
    • Haddad, F.1    Adams, G.R.2
  • 42
    • 78649853041 scopus 로고    scopus 로고
    • Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function
    • Murphy KT, Koopman R, Naim T, et al. Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function. FASEB J. 2010;24:4433-4442
    • (2010) FASEB J , vol.24 , pp. 4433-4442
    • Murphy, K.T.1    Koopman, R.2    Naim, T.3
  • 43
    • 0016684358 scopus 로고
    • The role of protein and lipids in stabilizing the activity of bovine heart succinate dehydrogenase
    • McPhail LC, Cunningham CC. The role of protein and lipids in stabilizing the activity of bovine heart succinate dehydrogenase. Biochemistry. 1975;14:1122-1131
    • (1975) Biochemistry , vol.14 , pp. 1122-1131
    • McPhail, L.C.1    Cunningham, C.C.2
  • 45
    • 34548512483 scopus 로고    scopus 로고
    • Autophagy in the heart and liver during normal aging and calorie restriction
    • Wohlgemuth SE, Julian D, Akin DE, et al. Autophagy in the heart and liver during normal aging and calorie restriction. Rejuvenation Res. 2007;10:281-292
    • (2007) Rejuvenation Res , vol.10 , pp. 281-292
    • Wohlgemuth, S.E.1    Julian, D.2    Akin, D.E.3
  • 46
    • 75049085555 scopus 로고    scopus 로고
    • Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise
    • Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C. Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise. Exp Gerontol. 2010;45:138-148
    • (2010) Exp Gerontol , vol.45 , pp. 138-148
    • Wohlgemuth, S.E.1    Seo, A.Y.2    Marzetti, E.3    Lees, H.A.4    Leeuwenburgh, C.5
  • 47
    • 0034704106 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation
    • Thomas M, Langley B, Berry C, et al. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J Biol Chem. 2000;275:40235-40243
    • (2000) J Biol Chem , vol.275 , pp. 40235-40243
    • Thomas, M.1    Langley, B.2    Berry, C.3
  • 48
    • 84865531266 scopus 로고    scopus 로고
    • Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway
    • Lee SJ, Huynh TV, Lee YS, et al. Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway. Proc Natl Acad Sci USA. 2012;109:E2353-E2360
    • (2012) Proc Natl Acad Sci USA , vol.109
    • Lee, S.J.1    Huynh, T.V.2    Lee, Y.S.3
  • 49
    • 66149128151 scopus 로고    scopus 로고
    • Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity
    • Amthor H, Otto A, Vulin A, et al. Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity. Proc Natl Acad Sci USA. 2009;106:7479-7484
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7479-7484
    • Amthor, H.1    Otto, A.2    Vulin, A.3
  • 50
    • 84861884365 scopus 로고    scopus 로고
    • Age-related changes in speed and mechanism of adult skeletal muscle stem cell migration
    • Collins-Hooper H, Woolley TE, Dyson L, et al. Age-related changes in speed and mechanism of adult skeletal muscle stem cell migration. Stem Cells. 2012;30:1182-1195
    • (2012) Stem Cells , vol.30 , pp. 1182-1195
    • Collins-Hooper, H.1    Woolley, T.E.2    Dyson, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.