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Volumn 26, Issue 6, 2012, Pages 2509-2521

Myostatin is associated with age-related human muscle stem cell dysfunction

Author keywords

Aging; Fiber type specific; GDF 8; Pax7

Indexed keywords

CELL PROTEIN; MESSENGER RNA; MYOD PROTEIN; MYOSTATIN;

EID: 84861771804     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-198663     Document Type: Article
Times cited : (133)

References (44)
  • 1
    • 0032899114 scopus 로고    scopus 로고
    • The pathophysiology of wasting in the elderly
    • Roubenoff, R. (1999) The pathophysiology of wasting in the elderly. J. Nutr. 129, 256S-259S.
    • (1999) J. Nutr. , vol.129
    • Roubenoff, R.1
  • 3
    • 0000642664 scopus 로고
    • Satellite cell of skeletal muscle fibers
    • Mauro, A. (1961) Satellite cell of skeletal muscle fibers. J. Biophys. Biochem. Cytol. 9, 493-495
    • (1961) J. Biophys. Biochem. Cytol. , vol.9 , pp. 493-495
    • Mauro, A.1
  • 4
    • 33646264523 scopus 로고    scopus 로고
    • Satellite-cell pool size does matter: Defining the myogenic potency of aging skeletal muscle
    • Shefer, G., Van de Mark, D. P., Richardson, J. B., and Yablonka- Reuveni, Z. (2006) Satellite-cell pool size does matter: defining the myogenic potency of aging skeletal muscle. Dev. Biol. 294, 50-66
    • (2006) Dev. Biol. , vol.294 , pp. 50-66
    • Shefer, G.1    Van De Mark, D.P.2    Richardson, J.B.3    Yablonka-Reuveni, Z.4
  • 5
    • 0344827208 scopus 로고    scopus 로고
    • Notch-Mediated Restoration of Regenerative Potential to Aged Muscle
    • DOI 10.1126/science.1087573
    • Conboy, I. M., Conboy, M. J., Smythe, G. M., and Rando, T. A. (2003) Notch-mediated restoration of regenerative potential to aged muscle. Science 302, 1575-1577 (Pubitemid 37475703)
    • (2003) Science , vol.302 , Issue.5650 , pp. 1575-1577
    • Conboy, I.H.1    Conboy, M.J.2    Smythe, G.M.3    Rando, T.A.4
  • 6
    • 33749658649 scopus 로고    scopus 로고
    • Aging increases the susceptibility of skeletal muscle derived satellite cells to apoptosis
    • DOI 10.1016/j.exger.2006.06.053, PII S0531556506002191
    • Jejurikar, S. S., Henkelman, E. A., Cederna, P. S., Marcelo, C. L., Urbanchek, M. G., and Kuzon, W. M., Jr. (2006) Aging increases the susceptibility of skeletal muscle-derived satellite cells to apoptosis. Exp.Gerontol. 41, 828-836 (Pubitemid 44557021)
    • (2006) Experimental Gerontology , vol.41 , Issue.9 , pp. 828-836
    • Jejurikar, S.S.1    Henkelman, E.A.2    Cederna, P.S.3    Marcelo, C.L.4    Urbanchek, M.G.5    Kuzon Jr., W.M.6
  • 7
    • 77951204583 scopus 로고    scopus 로고
    • The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny
    • Day, K., Shefer, G., Shearer, A., and Yablonka-Reuveni, Z. (2010) The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny. Dev. Biol. 340, 330-343
    • (2010) Dev. Biol. , vol.340 , pp. 330-343
    • Day, K.1    Shefer, G.2    Shearer, A.3    Yablonka-Reuveni, Z.4
  • 8
    • 13944261231 scopus 로고    scopus 로고
    • Rejuvenation of aged progenitor cells by exposure to a young systemic environment
    • DOI 10.1038/nature03260
    • Conboy, I. M., Conboy, M. J., Wagers, A. J., Girma, E. R., Weissman, I. L., and Rando, T. A. (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433, 760-764 (Pubitemid 40292986)
    • (2005) Nature , vol.433 , Issue.7027 , pp. 760-764
    • Conboy, I.M.1    Conboy, M.J.2    Wagers, A.J.3    Girma, E.R.4    Weismann, I.L.5    Rando, T.A.6
  • 9
    • 34547924424 scopus 로고    scopus 로고
    • Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
    • DOI 10.1126/science.1144090
    • Brack, A. S., Conboy, M. J., Roy, S., Lee, M., Kuo, C. J., Keller, C., and Rando, T. A. (2007) Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317, 807-810 (Pubitemid 47257918)
    • (2007) Science , vol.317 , Issue.5839 , pp. 807-810
    • Brack, A.S.1    Conboy, M.J.2    Roy, S.3    Lee, M.4    Kuo, C.J.5    Keller, C.6    Rando, T.A.7
  • 11
    • 0347361625 scopus 로고    scopus 로고
    • Satellite cells and myonuclei in young and elderly women and men
    • DOI 10.1002/mus.10510
    • Kadi, F., Charifi, N., Denis, C., and Lexell, J. (2004) Satellite cells and myonuclei in young and elderly women and men. Muscle Nerve 29, 120-127 (Pubitemid 38040565)
    • (2004) Muscle and Nerve , vol.29 , Issue.1 , pp. 120-127
    • Kadi, F.1    Charifi, N.2    Denis, C.3    Lexell, J.4
  • 13
    • 32144449569 scopus 로고    scopus 로고
    • Satellite cell numbers in young and older men 24 hours after eccentric exercise
    • DOI 10.1002/mus.20461
    • Dreyer, H. C., Blanco, C. E., Sattler, F. R., Schroeder, E. T., and Wiswell, R. A. (2006) Satellite cell numbers in young and older men 24 hours after eccentric exercise. Muscle Nerve 33, 242-253 (Pubitemid 43208681)
    • (2006) Muscle and Nerve , vol.33 , Issue.2 , pp. 242-253
    • Dreyer, H.C.1    Blanco, C.E.2    Sattler, F.R.3    Schroeder, E.T.4    Wiswell, R.A.5
  • 16
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron, A. C., Lawler, A. M., and Lee, S. J. (1997) Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387, 83-90 (Pubitemid 27202654)
    • (1997) Nature , vol.387 , Issue.6628 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.-J.3
  • 17
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee, S. J. (2004) Regulation of muscle mass by myostatin. Annu. Rev. Cell Dev. Biol. 20, 61-86
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 22
    • 33745813868 scopus 로고    scopus 로고
    • Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women
    • DOI 10.1152/japplphysiol.01616.2005
    • Raue, U., Slivka, D., Jemiolo, B., Hollon, C., and Trappe, S. (2006) Myogenic gene expression at rest and after a bout of resistance exercise in young (18-30 yr) and old (80-89 yr) women. J. Appl. Physiol. 101, 53-59 (Pubitemid 44035348)
    • (2006) Journal of Applied Physiology , vol.101 , Issue.1 , pp. 53-59
    • Raue, U.1    Slivka, D.2    Jemiolo, B.3    Hollon, C.4    Trappe, S.5
  • 23
    • 39449100832 scopus 로고    scopus 로고
    • Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation
    • Leger, B., Derave, W., De, B. K., Hespel, P., and Russell, A. P. (2008) Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation. Rejuv. Res. 11, 163B-175B
    • (2008) Rejuv. Res. , vol.11
    • Leger, B.1    Derave, W.2    De, B.K.3    Hespel, P.4    Russell, A.P.5
  • 24
    • 0141768237 scopus 로고    scopus 로고
    • Myostatin negatively regulates satellite cell activation and self-renewal
    • DOI 10.1083/jcb.200207056
    • McCroskery, S., Thomas, M., Maxwell, L., Sharma, M., and Kambadur, R. (2003) Myostatin negatively regulates satellite cell activation and self-renewal. J. Cell Biol. 162, 1135-1147 (Pubitemid 37174195)
    • (2003) Journal of Cell Biology , vol.162 , Issue.6 , pp. 1135-1147
    • McCroskery, S.1    Thomas, M.2    Maxwell, L.3    Sharma, M.4    Kambadur, R.5
  • 25
    • 0037147210 scopus 로고    scopus 로고
    • Myostatin inhibits myoblast differentiation by down-regulating MyoD expression
    • DOI 10.1074/jbc.M204291200
    • Langley, B., Thomas, M., Bishop, A., Sharma, M., Gilmour, S., and Kambadur, R. (2002) Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J. Biol. Chem. 277, 49831-49840 (Pubitemid 36014431)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49831-49840
    • Langley, B.1    Thomas, M.2    Bishop, A.3    Sharma, M.4    Gilmour, S.5    Kambadur, R.6
  • 26
    • 77956286244 scopus 로고    scopus 로고
    • Satellite cell number and cell cycle kinetics in response to acute myotrauma in humans: Immunohistochemistry versus flow cytometry
    • McKay, B. R., Toth, K. G., Tarnopolsky, M. A., and Parise, G. (2010) Satellite cell number and cell cycle kinetics in response to acute myotrauma in humans: immunohistochemistry versus flow cytometry. J. Physiol. 588, 3307-3320
    • (2010) J. Physiol. , vol.588 , pp. 3307-3320
    • McKay, B.R.1    Toth, K.G.2    Tarnopolsky, M.A.3    Parise, G.4
  • 28
    • 67650283899 scopus 로고    scopus 로고
    • Association of interleukin-6 signalling with the muscle stem cell response following muscle-lengthening contractions in humans
    • McKay, B. R., De, L. M., Johnston, A. P., O'Reilly, C. E., Phillips, S. M., Tarnopolsky, M. A., and Parise, G. (2009) Association of interleukin-6 signalling with the muscle stem cell response following muscle-lengthening contractions in humans. PLoS One 4, e6027
    • (2009) PLoS One , vol.4
    • McKay, B.R.1    De, L.M.2    Johnston, A.P.3    O'Reilly, C.E.4    Phillips, S.M.5    Tarnopolsky, M.A.6    Parise, G.7
  • 29
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K. J., and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 30
    • 77956302033 scopus 로고    scopus 로고
    • Myostatin is upregulated following stress in an Erkdependent manner and negatively regulates cardiomyocyte growth in culture and in a mouse model
    • Bish, L. T., Morine, K. J., Sleeper, M. M., and Sweeney, H. L. (2010) Myostatin is upregulated following stress in an Erkdependent manner and negatively regulates cardiomyocyte growth in culture and in a mouse model. PLoS One 5, e10230
    • (2010) PLoS One , vol.5
    • Bish, L.T.1    Morine, K.J.2    Sleeper, M.M.3    Sweeney, H.L.4
  • 31
    • 79952587664 scopus 로고    scopus 로고
    • Myostatin expression during human muscle hypertrophy and subsequent atrophy: Increased myostatin with detraining
    • Jespersen, J. G., Nedergaard, A., Andersen, L. L., Schjerling, P., and Andersen, J. L. (2011) Myostatin expression during human muscle hypertrophy and subsequent atrophy: increased myostatin with detraining. Scand. J. Med. Sci. Sports 21, 215-223
    • (2011) Scand. J. Med. Sci. Sports , vol.21 , pp. 215-223
    • Jespersen, J.G.1    Nedergaard, A.2    Andersen, L.L.3    Schjerling, P.4    Andersen, J.L.5
  • 33
    • 70349262639 scopus 로고    scopus 로고
    • New multiple labelling method for improved satellite cell identification in human muscle: Application to a cohort of power-lifters and sedentary men
    • Lindstrom, M., and Thornell, L. E. (2009) New multiple labelling method for improved satellite cell identification in human muscle: application to a cohort of power-lifters and sedentary men. Histochem. Cell Biol. 132, 141-157
    • (2009) Histochem. Cell Biol. , vol.132 , pp. 141-157
    • Lindstrom, M.1    Thornell, L.E.2
  • 34
    • 36248952802 scopus 로고    scopus 로고
    • The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions
    • Buckingham, M., and Relaix, F. (2007) The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions. Annu. Rev. Cell Dev. Biol. 23, 645-673
    • (2007) Annu. Rev. Cell Dev. Biol. , vol.23 , pp. 645-673
    • Buckingham, M.1    Relaix, F.2
  • 35
    • 0020509969 scopus 로고
    • Distribution of different fiber types in human skeletal muscles: Effects of aging studied in whole muscle cross sections
    • Lexell, J., Henriksson-Larsen, K., Winblad, B., and Sjostrom, M. (1983) Distribution of different fiber types in human skeletal muscles: effects of aging studied in whole muscle cross sections. Muscle Nerve 6, 588-595 (Pubitemid 13014083)
    • (1983) Muscle and Nerve , vol.6 , Issue.8 , pp. 588-595
    • Lexell, J.1    Henriksson, L.K.2    Winblad, B.3
  • 36
    • 79958767884 scopus 로고    scopus 로고
    • Myostatin: A novel insight into its role in metabolism, signal pathways, and expression regulation
    • Huang, Z., Chen, X., and Chen, D. (2011) Myostatin: A novel insight into its role in metabolism, signal pathways, and expression regulation. Cell. Signal. 23, 1441-1446
    • (2011) Cell. Signal. , vol.23 , pp. 1441-1446
    • Huang, Z.1    Chen, X.2    Chen, D.3
  • 37
    • 74949086718 scopus 로고    scopus 로고
    • Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways
    • Kovacheva, E. L., Hikim, A. P., Shen, R., Sinha, I., and Sinha-Hikim, I. (2010) Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways. Endocrinology 151, 628-638
    • (2010) Endocrinology , vol.151 , pp. 628-638
    • Kovacheva, E.L.1    Hikim, A.P.2    Shen, R.3    Sinha, I.4    Sinha-Hikim, I.5
  • 38
    • 19444370186 scopus 로고    scopus 로고
    • Impact of resistance loading on myostatin expression and cell cycle regulation in young and older men and women
    • DOI 10.1152/ajpendo.00464.2004
    • Kim, J. S., Cross, J. M., and Bamman, M. M. (2005) Impact of resistance loading on myostatin expression and cell cycle regulation in young and older men and women. Am. J. Physiol. Endocrinol. Metab. 288, E1110-E1119 (Pubitemid 40726797)
    • (2005) American Journal of Physiology - Endocrinology and Metabolism , vol.288 , Issue.6
    • Kim, J.-S.1    Cross, J.M.2    Bamman, M.M.3
  • 40
    • 0034663199 scopus 로고    scopus 로고
    • MyoD(-/-) satellite cells in single-fiber culture are differentiation defective and MRF4 deficient
    • DOI 10.1006/dbio.2000.9682
    • Cornelison, D. D., Olwin, B. B., Rudnicki, M. A., and Wold, B. J. (2000) MyoD(-/-) satellite cells in single-fiber culture are differentiation defective and MRF4 deficient. Dev. Biol. 224, 122-137 (Pubitemid 30660999)
    • (2000) Developmental Biology , vol.224 , Issue.2 , pp. 122-137
    • Cornelison, D.D.W.1    Olwin, B.B.2    Rudnicki, M.A.3    Wold, B.J.4
  • 41
    • 0034704106 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation
    • DOI 10.1074/jbc.M004356200
    • Thomas, M., Langley, B., Berry, C., Sharma, M., Kirk, S., Bass, J., and Kambadur, R. (2000) Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J. Biol. Chem. 275, 40235-40243 (Pubitemid 32064654)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.51 , pp. 40235-40243
    • Thomas, M.1    Langley, B.2    Berry, C.3    Sharma, M.4    Kirk, S.5    Bass, J.6    Kambadur, R.7
  • 43
    • 0029954208 scopus 로고    scopus 로고
    • MyoD is required for myogenic stem cell function in adult skeletal muscle
    • Megeney, L. A., Kablar, B., Garrett, K., Anderson, J. E., and Rudnicki, M. A. (1996) MyoD is required for myogenic stem cell function in adult skeletal muscle. Genes Dev. 10, 1173-1183 (Pubitemid 26171100)
    • (1996) Genes and Development , vol.10 , Issue.10 , pp. 1173-1183
    • Megeney, L.A.1    Kablar, B.2    Garrett, K.3    Anderson, J.E.4    Rudnicki, M.A.5
  • 44
    • 28044432532 scopus 로고    scopus 로고
    • Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and women
    • DOI 10.1152/japplphysiol.00513.2005
    • Kim, J. S., Kosek, D. J., Petrella, J. K., Cross, J. M., and Bamman, M. M. (2005) Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and women. J. Appl. Physiol. 99, 2149-2158 (Pubitemid 41691632)
    • (2005) Journal of Applied Physiology , vol.99 , Issue.6 , pp. 2149-2158
    • Kim, J.-S.1    Kosek, D.J.2    Petrella, J.K.3    Cross, J.M.4    Bamman, M.M.5


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