The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation

Circulation Research

Volumn 107, Issue 10, 2010, Pages 1209-1219

  Zhang, Jue ^a   Chang, Julia Y F ^a   Huang, Yanqing ^a   Lin, Xiang ^a   Luo, Yongde ^a   Schwartz, Robert J ^b   Martin, James F ^a   Wang, Fen ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b University of Houston   (United States)

Author keywords

BMP; cardiac valve defect; FGF; heart development; NCC differentiation

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR;

ARTICLE; CELL DIFFERENTIATION; ENDOCARDIAL CUSHION; HEART DEVELOPMENT; HEART LEFT VENTRICLE OUTFLOW TRACT; HEART RIGHT VENTRICLE OUTFLOW TRACT; HEART VALVE; NEURAL CREST CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; ENDOCARDIAL CUSHION DEFECTS; ENDOCARDIAL CUSHIONS; FIBROBLAST GROWTH FACTOR 2; GENOTYPE; HEART; HEART VALVES; MEMBRANE PROTEINS; MICE; MORPHOGENESIS; MYOCYTES, SMOOTH MUSCLE; NEURAL CREST; ORGAN CULTURE TECHNIQUES; PHENOTYPE; PROMOTER REGIONS, GENETIC; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 78549284554     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.225318     Document Type: Article

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