Intranuclear interactomic inhibition of FoxP3 suppresses functions of Treg cells

Biochemical and Biophysical Research Communications

Volumn 451, Issue 1, 2014, Pages 1-7

  Park, Jong Hyun ^a   Ko, Ji Seung ^a   Shin, Yoonchul ^a   Cho, Jen Young ^b   Oh, Han Ah ^a   Bothwell, Alfred M ^b   Lee, Sang Kyou ^a  

^a Yonsei University   (South Korea)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer immunotherapy; FoxP3; Intranuclear interactomic inhibitor of transcription factor; Protein transduction domain; Regulatory T cells

Indexed keywords

TRANSCRIPTION FACTOR FOXP3; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; INTERLEUKIN 10; INTERLEUKIN 2; TRANSCRIPTION FACTOR NFAT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER IMMUNOTHERAPY; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TUMOR MICROENVIRONMENT; AMINO ACID SEQUENCE; ANIMAL; CELL NUCLEUS; DOWN REGULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MUTANT MOUSE STRAIN; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SECRETION (PROCESS);

AMINO ACID SEQUENCE; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL NUCLEUS; CTLA-4 ANTIGEN; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-2; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; NFATC TRANSCRIPTION FACTORS; PROTEIN STRUCTURE, TERTIARY; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84906228432     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.06.141     Document Type: Article

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