Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation

Biochemical and Biophysical Research Communications

Volumn 451, Issue 1, 2014, Pages 112-118

  Zhu, Yun Rong ^a   Xu, Yong ^b   Fang, Jian Feng ^a   Zhou, Feng ^a   Deng, Xiong Wei ^a   Zhang, Yun Qing ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Apoptosis and signaling; Bufotalin; ER stress; Osteoblastoma

Indexed keywords

ANTINEOPLASTIC AGENT; BUFOTALIN; CASPASE 12; CASPASE INHIBITOR; CCAAT ENHANCER BINDING PROTEIN; CHINESE DRUG; PROTEIN IRE1; SALUBRINAL; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; BUFADIENOLIDE DERIVATIVE; CINNAMIC ACID DERIVATIVE; DDIT3 PROTEIN, HUMAN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; THIOUREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL DEATH; CHINESE MEDICINE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; OSTEOBLASTOMA; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; BONE NEOPLASMS; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; GENE SILENCING; GENETICS; MALE; METABOLISM; PATHOLOGY; SCID MOUSE;

MUS;

ANIMALS; APOPTOSIS; BONE NEOPLASMS; BUFANOLIDES; CASPASE 12; CINNAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; HUMANS; MALE; MICE; MICE, SCID; OSTEOBLASTOMA; THIOUREA; TRANSCRIPTION FACTOR CHOP; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84906227614     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.07.077     Document Type: Article

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