CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 307, Issue 4, 2014, Pages

  Moon, Hyung Geun ^a   Kim, Sang Heon ^a,b   Gao, Jinming ^c   Quan, Taihao ^d   Qin, Zhaoping ^d   Osorio, Juan C ^a   Rosas, Ivan O ^a,f   Wu, Min ^e   Tesfaigzi, Yohannes ^f   Jin, Yang ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Hanyang University College of Medicine   (South Korea)

^c PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^f LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Cigarette smoking; Cleaved CCN1; Full length CCN1; Matrix metalloproteinase 1

Indexed keywords

ALPHA7 INTEGRIN; CIGARETTE SMOKE; CYSTEINE RICH PROTEIN 61; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; PLASMIN; PROTEINASE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL FUNCTION; EXOSOME; EXTRACELLULAR MATRIX; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LONG TERM EXPOSURE; LUNG ALVEOLUS EPITHELIUM; LUNG EMPHYSEMA; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN MODIFICATION; PROTEIN SECRETION; RECEPTOR BINDING; SMOKING;

CIGARETTE SMOKING; CLEAVED CCN1; FULL-LENGTH CCN1; MATRIX METALLOPROTEINASE-1;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CYSTEINE-RICH PROTEIN 61; EMPHYSEMA; EPITHELIAL CELLS; FIBRINOLYSIN; HUMANS; INTEGRIN ALPHA CHAINS; INTERLEUKIN-8; LUNG; MALE; MATRIX METALLOPROTEINASE 1; MICE; NEUTROPHIL INFILTRATION; SMOKING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84906098407     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00102.2014     Document Type: Article

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