A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36

Genes and Development

Volumn 28, Issue 16, 2014, Pages 1758-1771

  Cheng, Zhongjun ^a   Cheung, Peggie ^b   Kuo, Alex J ^b   Yukl, Erik T ^c   Wilmot, Carrie M ^c   Gozani, Or ^b   Patel, Dinshaw J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b STANFORD UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Histone demethylase; KDM2A; Mechanism; Substrate specificity

Indexed keywords

HISTONE DEMETHYLASE; HISTONE H3; KDM2A PROTEIN; PROTEIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL FUNCTION; CELL TRANSFORMATION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DEMETHYLATION; DYNAMICS; EMBRYO; ENZYME REGULATION; ENZYME SPECIFICITY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING;

HISTONE DEMETHYLASE; KDM2A; MECHANISM; SUBSTRATE SPECIFICITY;

ANIMALS; BINDING SITES; CELL LINE; GENOMIC INSTABILITY; HISTONES; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; METHYLATION; MICE; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY;

EID: 84906096235     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.246561.114     Document Type: Article

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