Crystal structure of the PHF8 Jumonji domain, an Nε-methyl lysine demethylase

FEBS Letters

Volumn 584, Issue 4, 2010, Pages 825-830

  Yue, Wyatt W ^a   Hozjan, Viktorija ^a   Ge, Wei ^c   Loenarz, Christoph ^c   Cooper, Christopher D O ^a   Schofield, Christopher J ^c   Kavanagh, Kathryn L ^a   Oppermann, Udo ^a,b   McDonough, Michael A ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NIHR OXFORD BIOMEDICAL RESEARCH CENTRE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

2 Oxoglutarate oxygenase; Epigenetic modification; Histone lysine demethylase; JmjC; Transcriptional regulation

Indexed keywords

2 OXOGLUTARIC ACID; F BOX AND LEUCINE RICH REPEAT 10 PROTEIN; F BOX PROTEIN; LYSINE; OXYGENASE; PHD FINGER PROTEIN 8; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; BINDING SITE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; MOLECULAR IMAGING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN METHYLATION; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; IRON; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; KETOGLUTARIC ACIDS; LYSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

EID: 77649270417     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.12.055     Document Type: Article

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