Inflammasome activation by cystine crystals: Implications for the pathogenesis of cystinosis

Journal of the American Society of Nephrology

Volumn 25, Issue 6, 2014, Pages 1163-1169

  Prencipe, Giusi ^a   Caiello, Ivan ^a   Cherqui, Stephanie ^c   Whisenant, Thomas ^d   Petrini, Stefania ^b   Emma, Francesco ^a   De Benedetti, Fabrizio ^a  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b Research Laboratories ^*  (Italy)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CYSTINE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; REACTIVE OXYGEN METABOLITE; AMINO ACID TRANSPORTER; CTNS PROTEIN, HUMAN; CYSTINOSIN PROTEIN, MOUSE; IL1B PROTEIN, MOUSE;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYSTINOSIS; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MONOCYTE; MOUSE; NONHUMAN; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN SECRETION; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMISTRY; CHRONIC KIDNEY DISEASE; CHRONIC KIDNEY FAILURE; CRYSTALLIZATION; CYTOLOGY; GENETIC RENAL DISEASE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MONONUCLEAR CELL; PRESCHOOL CHILD; SECRETION (PROCESS); YOUNG ADULT;

CHRONIC KIDNEY DISEASE; GENETIC RENAL DISEASE; IMMUNOLOGY;

ADOLESCENT; ADULT; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CRYSTALLIZATION; CYSTINE; CYSTINOSIS; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RENAL INSUFFICIENCY, CHRONIC; YOUNG ADULT;

EID: 84906091599     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013060653     Document Type: Article

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