Suppressive action of acetate on interleukin-8 production via tubulin- acetylation

Immunology and Cell Biology

Volumn 92, Issue 7, 2014, Pages 624-630

  Ishiguro, Kazuhiro ^a   Ando, Takafumi ^a   Maeda, Osamu ^a   Watanabe, Osamu ^a   Goto, Hidemi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ALPHA TUBULIN; BIOLOGICAL MARKER; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FLAGELLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MESSENGER RNA; PROTEIN C FOS; RAP1 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR NFAT; ACETIC ACID DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BINDING; TUBULIN;

ACETYLATION; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; CELL VIABILITY; COLON MUCOSA; CYTOKINE PRODUCTION; HUMAN; HUMAN TISSUE; INTESTINE EPITHELIUM CELL; LARGE INTESTINE; MALE; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL LINE; COLON; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE SUBPOPULATION;

ACETATES; ACETYLATION; ANIMALS; CELL LINE; COLON; ETS-DOMAIN PROTEIN ELK-1; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAGELLIN; HUMANS; INTERLEUKIN-8; INTESTINAL MUCOSA; MALE; MICE; PROTEIN BINDING; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; TUBULIN;

EID: 84906069554     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2014.31     Document Type: Article

References (41)

1. Abreu MT, Fukata M, Arditi M. TLR signaling in the gut in health and disease. J Immunol 2005; 174: 4453-4460.
2. Kumar H, Kawai T, Akira S. Pathogen recognition by the innate immune system. Int Rev Immunol 2011; 30: 16-34.
3. Chassaing B, Darfeuille-Michaud A. The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases. Gastroenterology 2011; 140: 1720-1728.
4. Abraham C, Medzhitov R. Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology 2011; 140: 1729-1737.
5. O'Hara AM, Shanahan F. The gut flora as a forgotten organ. EMBO Rep 2006; 7: 688-693. (Pubitemid 43986264)
6. Atarashi K, Tanoue T, Oshima K, Suda W, Nagano Y, Nishikawa H et al. Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. Nature 2013; 500: 232-236.
7. Atarashi K, Tanoue T, Shima T, Imaoka A, Kuwahara T, Momose Y et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011; 331: 337-341.
8. Matsumoto M, Kibe R, Ooga T, Aiba Y, Kurihara S, Sawaki E et al. Impact of intestinal microbiota on intestinal luminal metabolome. Sci Rep 2012; 2: 233.
9. Wong JM, de Souza R, Kendall CW, Emam A, Jenkins DJ. Colonic health: Fermentation and short chain fatty acids. J Clin Gastroenterol 2006; 40: 235-243. (Pubitemid 44309560)
10. Van der Meulen R, Adriany T, Verbrugghe K, De Vuyst L. Kinetic analysis of bifidobacterial metabolism reveals a minor role for succinic acid in the regeneration of NAD\+ through its growth-associated production. Appl Environ Microbiol 2006; 72: 5204-5210.
11. Ishiguro K, Ando T, Maeda O, Ohmiya N, Niwa Y, Goto H. Acetate inhibits NFAT activation in T cells via importin beta1 interference. Eur J Immunol 2007; 37: 2309-2316. (Pubitemid 47250222)
12. Fukuda S, Toh H, Hase K, Oshima K, Nakanishi Y, Yoshimura K et al. Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature 2011; 469: 543-547.
13. Patz J, Jacobsohn WZ, Gottschalk-Sabag S, Zeides S, Braverman DZ. Treatment of refractory distal ulcerative colitis with short chain fatty acid enemas. Am J Gastroenterol 1996; 91: 731-734. (Pubitemid 26117953)
14. Vernia P, Marcheggiano A, Caprilli R, Frieri G, Corrao G, Valpiani D et al. Short-chain fatty acid topical treatment in distal ulcerative colitis. Aliment Pharmacol Ther 1995; 9: 309-313.
15. Steinhart AH, Hiruki T, Brzezinski A, Baker JP. Treatment of left-sided ulcerative colitis with butyrate enemas: A controlled trial. Aliment Pharmacol Ther 1996; 10: 729-736. (Pubitemid 26340202)
16. Ishiguro K, Ando T, Maeda O, Watanabe O, Goto H. Cutting edge: Tubulin alpha functions as an adaptor in NFAT-importin beta interaction. J Immunol 2011; 186: 2710-2713.
17. Hammond JW, Cai D, Verhey KJ. Tubulin modifications and their cellular functions. Curr Opin Cell Biol 2008; 20: 71-76.
18. Akella JS, Wloga D, Kim J, Starostina NG, Lyons-Abbott S, Morrissette NS et al. MEC-17 is an alpha-tubulin acetyltransferase. Nature 2010; 467: 218-222.
19. Eferl R, Wagner EF. AP-1: A double-edged sword in tumorigenesis. Nat Rev Cancer 2003; 3: 859-868. (Pubitemid 37383716)
20. Yordy JS, Muise-Helmericks RC. Signal transduction and the Ets family of transcription factors. Oncogene 2000; 19: 6503-6513. (Pubitemid 32108440)
21. Hoffmann E, Dittrich-Breiholz O, Holtmann H, Kracht M. Multiple control of interleukin-8 gene expression. J Leukoc Biol 2002; 72: 847-855. (Pubitemid 35365158)
22. Iourgenko V, Zhang W, Mickanin C, Daly I, Jiang C, Hexham JM et al. Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci USA 2003; 100: 12147-12152. (Pubitemid 37271529)
23. Hisatsune J, Nakayama M, Isomoto H, Kurazono H, Mukaida N, Mukhopadhyay AK et al. Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation. J Immunol 2008; 180: 5017-5027.
24. Kovacs KJ. c-Fos as a transcription factor: A stressful (re)view from a functional map. Neurochem Int 1998; 33: 287-297. (Pubitemid 28529506)
25. Kogut MH, Genovese KJ, He H. Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1. Mol Immunol 2007; 44: 1729-1736.
26. Hattori M, Minato N. Rap1 GTPase: Functions, regulation, and malignancy. J Biochem 2003; 134: 479-484. (Pubitemid 37442869)
27. Gloerich M, Bos JL. Regulating Rap small G-proteins in time and space. Trends Cell Biol 2011; 21: 615-623.
28. Pannekoek WJ, Kooistra MR, Zwartkruis FJ, Bos JL. Cell-cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors. Biochim Biophys Acta 2009; 1788: 790-796.
29. Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007; 448: 427-434. (Pubitemid 47123518)
30. Knights D, Lassen KG, Xavier RJ. Advances in inflammatory bowel disease pathogenesis: Linking host genetics and the microbiome. Gut 2013; 62: 1505-1510.
31. Gophna U, Sommerfeld K, Gophna S, Doolittle WF, Veldhuyzen van Zanten SJ. Differences between tissue-associated intestinal microfloras of patients with Crohn's disease and ulcerative colitis. J Clin Microbiol 2006; 44: 4136-4141. (Pubitemid 44737260)
32. Andoh A, Imaeda H, Aomatsu T, Inatomi O, Bamba S, Sasaki M et al. Comparison of the fecal microbiota profiles between ulcerative colitis and Crohn's disease using terminal restriction fragment length polymorphism analysis. J Gastroenterol 2011; 46: 479-486.
33. Preidis GA, Versalovic J. Targeting the human microbiome with antibiotics, probiotics, and prebiotics: Gastroenterology enters the metagenomics era. Gastroenterology 2009; 136: 2015-2031.
34. Marchesi JR, Holmes E, Khan F, Kochhar S, Scanlan P, Shanahan F et al. Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. J Proteome Res 2007; 6: 546-551. (Pubitemid 46340158)
35. Treem WR, Ahsan N, Shoup M, Hyams JS. Fecal short-chain fatty acids in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1994; 18: 159-164. (Pubitemid 24056473)
36. Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly YM et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 2013; 341: 569-573.
37. Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 2013; 504: 446-450.
38. Chang PV, Hao L, Offermanns S, Medzhitov R. The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc Natl Acad Sci USA 2014; 111: 2247-2252.
39. Macfarlane S, Macfarlane GT. Regulation of short-chain fatty acid production. Proc Nutr Soc 2003; 62: 67-72.
40. Cho JH, Brant SR. Recent insights into the genetics of inflammatory bowel disease. Gastroenterology 2011; 140: 1704-1712.
41. Ishiguro K, Xavier R. Homer-3 regulates activation of serum response element in T cells via its EVH1 domain. Blood 2004; 103: 2248-2256. (Pubitemid 38326244)