-
2
-
-
34247877577
-
The fuzzy logic of physiological cardiac hypertrophy
-
DornGW,II. 2007. The fuzzy logic of physiological cardiac hypertrophy. Hypertension 49:962-970. http://dx.doi.org/10.1161/HYPERTENSIONAHA.106.079426.
-
(2007)
Hypertension
, vol.49
, pp. 962-970
-
-
Dorn II, G.W.1
-
3
-
-
33845711358
-
Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway
-
Shiojima I, Walsh K. 2006. Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway. Genes Dev. 20:3347-3365. http://dx.doi.org/10.1101/gad.1492806.
-
(2006)
Genes Dev.
, vol.20
, pp. 3347-3365
-
-
Shiojima, I.1
Walsh, K.2
-
4
-
-
0036192939
-
Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression
-
Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE, Taegtmeyer H, Severson D, Kahn CR, Abel ED. 2002. Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression. J. Clin. Invest. 109:629-639. http://dx.doi.org/10.1172/JCI13946.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 629-639
-
-
Belke, D.D.1
Betuing, S.2
Tuttle, M.J.3
Graveleau, C.4
Young, M.E.5
Pham, M.6
Zhang, D.7
Cooksey, R.C.8
McClain, D.A.9
Litwin, S.E.10
Taegtmeyer, H.11
Severson, D.12
Kahn, C.R.13
Abel, E.D.14
-
5
-
-
55049090844
-
Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy
-
Kim J, Wende AR, Sena S, Theobald HA, Soto J, Sloan C, Wayment BE, Litwin SE, Holzenberger M, LeRoith D, Abel ED. 2008. Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy. Mol. Endocrinol. 22:2531-2543. http://dx.doi.org/10.1210/me.2008-0265.
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 2531-2543
-
-
Kim, J.1
Wende, A.R.2
Sena, S.3
Theobald, H.A.4
Soto, J.5
Sloan, C.6
Wayment, B.E.7
Litwin, S.E.8
Holzenberger, M.9
LeRoith, D.10
Abel, E.D.11
-
6
-
-
63649106676
-
Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart
-
Boudina S, Bugger H, Sena S, O'Neill BT, Zaha VG, Ilkun O, Wright JJ, Mazumder PK, Palfreyman E, Tidwell TJ, Theobald H, Khalimonchuk O, Wayment B, Sheng X, Rodnick KJ, Centini R, Chen D, Litwin SE, Weimer BE, Abel ED. 2009. Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart. Circulation 119:1272-1283. http://dx.doi.org/10.1161/CIRCULATIONAHA.108.792101.
-
(2009)
Circulation
, vol.119
, pp. 1272-1283
-
-
Boudina, S.1
Bugger, H.2
Sena, S.3
O'Neill, B.T.4
Zaha, V.G.5
Ilkun, O.6
Wright, J.J.7
Mazumder, P.K.8
Palfreyman, E.9
Tidwell, T.J.10
Theobald, H.11
Khalimonchuk, O.12
Wayment, B.13
Sheng, X.14
Rodnick, K.J.15
Centini, R.16
Chen, D.17
Litwin, S.E.18
Weimer, B.E.19
Abel, E.D.20
more..
-
7
-
-
0035941414
-
Increased cardiac sympathetic activity and insulin-like growth factor-I formation are associated with physiological hypertrophy in athletes
-
Neri Serneri GG, Boddi M, Modesti PA, Cecioni I, Coppo M, Padeletti L, Michelucci A, Colella A, Galanti G. 2001. Increased cardiac sympathetic activity and insulin-like growth factor-I formation are associated with physiological hypertrophy in athletes. Circ. Res. 89:977-982. http://dx.doi.org/10.1161/hh2301.100982.
-
(2001)
Circ. Res.
, vol.89
, pp. 977-982
-
-
Neri Serneri, G.G.1
Boddi, M.2
Modesti, P.A.3
Cecioni, I.4
Coppo, M.5
Padeletti, L.6
Michelucci, A.7
Colella, A.8
Galanti, G.9
-
8
-
-
0037292011
-
Short- and long-term swimming exercise training increases myocardial insulin-like growth factor- I gene expression
-
Scheinowitz M, Kessler-Icekson G, Freimann S, Zimmermann R, Schaper W, Golomb E, Savion N, Eldar M. 2003. Short- and long-term swimming exercise training increases myocardial insulin-like growth factor- I gene expression. Growth Horm. IGF Res. 13:19-25. http://dx.doi.org/10.1016/S1096-6374(02)00137-5.
-
(2003)
Growth Horm. IGF Res.
, vol.13
, pp. 19-25
-
-
Scheinowitz, M.1
Kessler-Icekson, G.2
Freimann, S.3
Zimmermann, R.4
Schaper, W.5
Golomb, E.6
Savion, N.7
Eldar, M.8
-
9
-
-
33646449520
-
Akt1 is required for physiological cardiac growth
-
DeBosch B, Treskov I, Lupu TS, Weinheimer C, Kovacs A, Courtois M, Muslin AJ. 2006. Akt1 is required for physiological cardiac growth. Circulation 113:2097-2104. http://dx.doi.org/10.1161/CIRCULATIONAHA.105.595231.
-
(2006)
Circulation
, vol.113
, pp. 2097-2104
-
-
DeBosch, B.1
Treskov, I.2
Lupu, T.S.3
Weinheimer, C.4
Kovacs, A.5
Courtois, M.6
Muslin, A.J.7
-
10
-
-
0142027759
-
Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
-
McMullen JR, Shioi T, Zhang L, Tarnavski O, Sherwood MC, Kang PM, Izumo S. 2003. Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc. Natl. Acad. Sci. U. S. A. 100:12355-12360. http://dx.doi.org/10.1073/pnas.1934654100.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 12355-12360
-
-
McMullen, J.R.1
Shioi, T.2
Zhang, L.3
Tarnavski, O.4
Sherwood, M.C.5
Kang, P.M.6
Izumo, S.7
-
11
-
-
10744223902
-
The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway
-
McMullen JR, Shioi T, Huang WY, Zhang L, Tarnavski O, Bisping E, Schinke M, Kong S, Sherwood MC, Brown J, Riggi L, Kang PM, Izumo S. 2004. The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway. J. Biol. Chem. 279:4782-4793. http://dx.doi.org/10.1074/jbc.M310405200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4782-4793
-
-
McMullen, J.R.1
Shioi, T.2
Huang, W.Y.3
Zhang, L.4
Tarnavski, O.5
Bisping, E.6
Schinke, M.7
Kong, S.8
Sherwood, M.C.9
Brown, J.10
Riggi, L.11
Kang, P.M.12
Izumo, S.13
-
12
-
-
34548850040
-
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy
-
O'Neill BT, Kim J, Wende AR, Theobald HA, Tuinei J, Buchanan J, Guo A, Zaha VG, Davis DK, Schell JC, Boudina S, Wayment B, Litwin SE, Shioi T, Izumo S, Birnbaum MJ, Abel ED. 2007. A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy. Cell Metab. 6:294-306. http://dx.doi.org/10.1016/j.cmet.2007.09.001.
-
(2007)
Cell Metab.
, vol.6
, pp. 294-306
-
-
O'Neill, B.T.1
Kim, J.2
Wende, A.R.3
Theobald, H.A.4
Tuinei, J.5
Buchanan, J.6
Guo, A.7
Zaha, V.G.8
Davis, D.K.9
Schell, J.C.10
Boudina, S.11
Wayment, B.12
Litwin, S.E.13
Shioi, T.14
Izumo, S.15
Birnbaum, M.J.16
Abel, E.D.17
-
13
-
-
0028032895
-
Alternative pathway of insulin signalling in mice withtargeted disruption of the IRS-1 gene
-
Araki E, Lipes MA, Patti ME, Bruning JC, Haag B, III, Johnson RS, Kahn CR. 1994. Alternative pathway of insulin signalling in mice withtargeted disruption of the IRS-1 gene. Nature 372:186-190. http://dx.doi.org/10.1038/372186a0.
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Bruning, J.C.4
Haag III, B.5
Johnson, R.S.6
Kahn, C.R.7
-
14
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto H, Kadowaki T, Tobe K, Yagi T, Sakura H, Hayakawa T, Terauchi Y, Ueki K, Kaburagi Y, Satoh S, Sekihara H, Yoshioka S, Horikoshi H, Furuta Y, Ikawa Y, Kasuga M, Yazaki Y, Aizawa S. 1994. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature 372:182-186. http://dx.doi.org/10.1038/372182a0.
-
(1994)
Nature
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Yagi, T.4
Sakura, H.5
Hayakawa, T.6
Terauchi, Y.7
Ueki, K.8
Kaburagi, Y.9
Satoh, S.10
Sekihara, H.11
Yoshioka, S.12
Horikoshi, H.13
Furuta, Y.14
Ikawa, Y.15
Kasuga, M.16
Yazaki, Y.17
Aizawa, S.18
-
15
-
-
0032567937
-
Disruption of IRS-2 causes type 2 diabetes in mice
-
Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, White MF. 1998. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391:900-904. http://dx.doi.org/10.1038/36116.
-
(1998)
Nature
, vol.391
, pp. 900-904
-
-
Withers, D.J.1
Gutierrez, J.S.2
Towery, H.3
Burks, D.J.4
Ren, J.M.5
Previs, S.6
Zhang, Y.7
Bernal, D.8
Pons, S.9
Shulman, G.I.10
Bonner-Weir, S.11
White, M.F.12
-
16
-
-
0033393822
-
Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart
-
Abel ED, Kaulbach HC, Tian R, Hopkins JC, Duffy J, Doetschman T, Minnemann T, Boers ME, Hadro E, Oberste-Berghaus C, Quist W, Lowell BB, Ingwall JS, Kahn BB. 1999. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. J. Clin. Invest. 104:1703-1714. http://dx.doi.org/10.1172/JCI7605.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1703-1714
-
-
Abel, E.D.1
Kaulbach, H.C.2
Tian, R.3
Hopkins, J.C.4
Duffy, J.5
Doetschman, T.6
Minnemann, T.7
Boers, M.E.8
Hadro, E.9
Oberste-Berghaus, C.10
Quist, W.11
Lowell, B.B.12
Ingwall, J.S.13
Kahn, B.B.14
-
17
-
-
45549090182
-
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
-
Dong XC, Copps KD, Guo S, Li Y, Kollipara R, DePinho RA, White MF. 2008. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell Metab. 8:65-76. http://dx.doi.org/10.1016/j.cmet.2008.06.006.
-
(2008)
Cell Metab.
, vol.8
, pp. 65-76
-
-
Dong, X.C.1
Copps, K.D.2
Guo, S.3
Li, Y.4
Kollipara, R.5
DePinho, R.A.6
White, M.F.7
-
18
-
-
9644260563
-
Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes
-
Lin X, Taguchi A, Park S, Kushner JA, Li F, Li Y, White MF. 2004. Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes. J. Clin. Invest. 114:908-916. http://dx.doi.org/10.1172/JCI22217.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 908-916
-
-
Lin, X.1
Taguchi, A.2
Park, S.3
Kushner, J.A.4
Li, F.5
Li, Y.6
White, M.F.7
-
19
-
-
80052970004
-
PGC-1beta deficiency accelerates the transition to heart failure in pressure overload hypertrophy
-
Riehle C, Wende AR, Zaha VG, Pires KM, Wayment B, Olsen C, Bugger H, Buchanan J, Wang X, Moreira AB, Doenst T, Medina-Gomez G, Litwin SE, Lelliott CJ, Vidal-Puig A, Abel ED. 2011. PGC-1beta deficiency accelerates the transition to heart failure in pressure overload hypertrophy. Circ. Res. 109:783-793. http://dx.doi.org/10.1161/CIRCRESAHA.111.243964.
-
(2011)
Circ. Res.
, vol.109
, pp. 783-793
-
-
Riehle, C.1
Wende, A.R.2
Zaha, V.G.3
Pires, K.M.4
Wayment, B.5
Olsen, C.6
Bugger, H.7
Buchanan, J.8
Wang, X.9
Moreira, A.B.10
Doenst, T.11
Medina-Gomez, G.12
Litwin, S.E.13
Lelliott, C.J.14
Vidal-Puig, A.15
Abel, E.D.16
-
20
-
-
36349030319
-
Cardiac hypertrophy caused by peroxisome proliferator-activated receptor-gamma agonist treatment occurs independently of changes in myocardial insulin signaling
-
Sena S, Rasmussen IR, Wende AR, McQueen AP, Theobald HA, Wilde N, Pereira RO, Litwin SE, Berger JP, Abel ED. 2007. Cardiac hypertrophy caused by peroxisome proliferator-activated receptor-gamma agonist treatment occurs independently of changes in myocardial insulin signaling. Endocrinology 148:6047-6053. http://dx.doi.org/10.1210/en.2006-1559.
-
(2007)
Endocrinology
, vol.148
, pp. 6047-6053
-
-
Sena, S.1
Rasmussen, I.R.2
Wende, A.R.3
McQueen, A.P.4
Theobald, H.A.5
Wilde, N.6
Pereira, R.O.7
Litwin, S.E.8
Berger, J.P.9
Abel, E.D.10
-
21
-
-
84890026772
-
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart
-
Riehle C, Wende AR, Sena S, Pires KM, Pereira RO, Zhu Y, Bugger H, Frank D, Bevins J, Chen D, Perry CN, Dong XC, Valdez S, Rech Sheng MX, Weimer BC, Gottlieb RA, White MF, Abel ED. 2013. Insulin receptor substrate signaling suppresses neonatal autophagy in the heart. J. Clin. Invest. 123:5319-5333. http://dx.doi.org/10.1172/JCI71171.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 5319-5333
-
-
Riehle, C.1
Wende, A.R.2
Sena, S.3
Pires, K.M.4
Pereira, R.O.5
Zhu, Y.6
Bugger, H.7
Frank, D.8
Bevins, J.9
Chen, D.10
Perry, C.N.11
Dong, X.C.12
Valdez, S.13
Rech Sheng, M.X.14
Weimer, B.C.15
Gottlieb, R.A.16
White, M.F.17
Abel, E.D.18
-
22
-
-
80052454265
-
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1
-
Haemmerle G, Moustafa T, Woelkart G, Buttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rulicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. 2011. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nat. Med. 17:1076-1085. http://dx.doi.org/10.1038/nm.2439.
-
(2011)
Nat. Med.
, vol.17
, pp. 1076-1085
-
-
Haemmerle, G.1
Moustafa, T.2
Woelkart, G.3
Buttner, S.4
Schmidt, A.5
van de Weijer, T.6
Hesselink, M.7
Jaeger, D.8
Kienesberger, P.C.9
Zierler, K.10
Schreiber, R.11
Eichmann, T.12
Kolb, D.13
Kotzbeck, P.14
Schweiger, M.15
Kumari, M.16
Eder, S.17
Schoiswohl, G.18
Wongsiriroj, N.19
Pollak, N.M.20
Radner, F.P.21
Preiss-Landl, K.22
Kolbe, T.23
Rulicke, T.24
Pieske, B.25
Trauner, M.26
Lass, A.27
Zimmermann, R.28
Hoefler, G.29
Cinti, S.30
Kershaw, E.E.31
Schrauwen, P.32
Madeo, F.33
Mayer, B.34
Zechner, R.35
more..
-
23
-
-
37549025047
-
A role for the transcriptional coactivator PGC-1alpha in muscle refueling
-
Wende AR, Schaeffer PJ, Parker GJ, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JM, McClain DA, Holloszy JO, Kelly DP. 2007. A role for the transcriptional coactivator PGC-1alpha in muscle refueling. J. Biol. Chem. 282:36642-36651. http://dx.doi.org/10.1074/jbc.M707006200.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36642-36651
-
-
Wende, A.R.1
Schaeffer, P.J.2
Parker, G.J.3
Zechner, C.4
Han, D.H.5
Chen, M.M.6
Hancock, C.R.7
Lehman, J.J.8
Huss, J.M.9
McClain, D.A.10
Holloszy, J.O.11
Kelly, D.P.12
-
24
-
-
0037205315
-
Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development
-
Hardt SE, Sadoshima J. 2002. Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development. Circ. Res. 90:1055-1063. http://dx.doi.org/10.1161/01.RES.0000018952.70505.F1.
-
(2002)
Circ. Res.
, vol.90
, pp. 1055-1063
-
-
Hardt, S.E.1
Sadoshima, J.2
-
25
-
-
0033153166
-
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
-
Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, Hoekstra MF, Aebersold R, Sonenberg N. 1999. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism. Genes Dev. 13:1422-1437. http://dx.doi.org/10.1101/gad.13.11.1422.
-
(1999)
Genes Dev.
, vol.13
, pp. 1422-1437
-
-
Gingras, A.C.1
Gygi, S.P.2
Raught, B.3
Polakiewicz, R.D.4
Abraham, R.T.5
Hoekstra, M.F.6
Aebersold, R.7
Sonenberg, N.8
-
26
-
-
0028237871
-
Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts
-
Chen J, Parsons S, Brautigan DL. 1994. Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts. J. Biol. Chem. 269:7957-7962.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7957-7962
-
-
Chen, J.1
Parsons, S.2
Brautigan, D.L.3
-
27
-
-
0026786471
-
Regulation of protein serinethreonine phosphatase type-2A by tyrosine phosphorylation
-
Chen J, Martin BL, Brautigan DL. 1992. Regulation of protein serinethreonine phosphatase type-2A by tyrosine phosphorylation. Science 257: 1261-1264. http://dx.doi.org/10.1126/science.1325671.
-
(1992)
Science
, vol.257
, pp. 1261-1264
-
-
Chen, J.1
Martin, B.L.2
Brautigan, D.L.3
-
28
-
-
4544314719
-
Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes
-
Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagi A, Olefsky JM. 2004. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes. Mol. Cell. Biol. 24:8778-8789. http://dx.doi.org/10.1128/MCB.24.19.8778-8789.2004.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8778-8789
-
-
Ugi, S.1
Imamura, T.2
Maegawa, H.3
Egawa, K.4
Yoshizaki, T.5
Shi, K.6
Obata, T.7
Ebina, Y.8
Kashiwagi, A.9
Olefsky, J.M.10
-
29
-
-
0042062296
-
Determinants for the inter-action between Janus kinase 2 and protein phosphatase 2A
-
Yokoyama N, Reich NC, Miller WT. 2003. Determinants for the inter-action between Janus kinase 2 and protein phosphatase 2A. Arch. Biochem. Biophys. 417:87-95. http://dx.doi.org/10.1016/S0003-9861(03)00333-3.
-
(2003)
Arch. Biochem. Biophys.
, vol.417
, pp. 87-95
-
-
Yokoyama, N.1
Reich, N.C.2
Miller, W.T.3
-
30
-
-
2442637820
-
Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity
-
Argetsinger LS, Kouadio JL, Steen H, Stensballe A, Jensen ON, Carter-Su C. 2004. Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity. Mol. Cell. Biol. 24:4955-4967. http://dx.doi.org/10.1128/MCB.24.11.4955-4967.2004.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4955-4967
-
-
Argetsinger, L.S.1
Kouadio, J.L.2
Steen, H.3
Stensballe, A.4
Jensen, O.N.5
Carter-Su, C.6
-
31
-
-
0034613161
-
Regulation of STAT3 by direct binding to the Rac1 GTPase
-
Simon AR, Vikis HG, Stewart S, Fanburg BL, Cochran BH, Guan KL. 2000. Regulation of STAT3 by direct binding to the Rac1 GTPase. Science 290:144-147. http://dx.doi.org/10.1126/science.290.5489.144.
-
(2000)
Science
, vol.290
, pp. 144-147
-
-
Simon, A.R.1
Vikis, H.G.2
Stewart, S.3
Fanburg, B.L.4
Cochran, B.H.5
Guan, K.L.6
-
32
-
-
4143052419
-
Regular exercise is associated with a protective metabolic phenotype in the rat heart
-
Burelle Y, Wambolt RB, Grist M, Parsons HL, Chow JC, Antler C, Bonen A, Keller A, Dunaway GA, Popov KM, Hochachka PW, Allard MF. 2004. Regular exercise is associated with a protective metabolic phenotype in the rat heart. Am. J. Physiol. Heart Circ. Physiol. 287:H1055-H1063. http://dx.doi.org/10.1152/ajpheart.00925.2003.
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.287
-
-
Burelle, Y.1
Wambolt, R.B.2
Grist, M.3
Parsons, H.L.4
Chow, J.C.5
Antler, C.6
Bonen, A.7
Keller, A.8
Dunaway, G.A.9
Popov, K.M.10
Hochachka, P.W.11
Allard, M.F.12
-
33
-
-
27144536566
-
Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy
-
Luo J, McMullen JR, Sobkiw CL, Zhang L, Dorfman AL, Sherwood MC, Logsdon MN, Horner JW, DePinho RA, Izumo S, Cantley LC. 2005. Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy. Mol. Cell. Biol. 25:9491-9502. http://dx.doi.org/10.1128/MCB.25.21.9491-9502.2005.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9491-9502
-
-
Luo, J.1
McMullen, J.R.2
Sobkiw, C.L.3
Zhang, L.4
Dorfman, A.L.5
Sherwood, M.C.6
Logsdon, M.N.7
Horner, J.W.8
DePinho, R.A.9
Izumo, S.10
Cantley, L.C.11
-
34
-
-
0034213075
-
The conserved phosphoinositide 3-kinase pathwaydetermines heart size in mice
-
Shioi T, Kang PM, Douglas PS, Hampe J, Yballe CM, Lawitts J, Cantley LC, Izumo S. 2000. The conserved phosphoinositide 3-kinase pathwaydetermines heart size in mice. EMBO J. 19:2537-2548. http://dx.doi.org/10.1093/emboj/19.11.2537.
-
(2000)
EMBO J.
, vol.19
, pp. 2537-2548
-
-
Shioi, T.1
Kang, P.M.2
Douglas, P.S.3
Hampe, J.4
Yballe, C.M.5
Lawitts, J.6
Cantley, L.C.7
Izumo, S.8
-
35
-
-
70349734861
-
Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy
-
Ikeda H, Shiojima I, Ozasa Y, Yoshida M, Holzenberger M, Kahn CR, Walsh K, Igarashi T, Abel ED, Komuro I. 2009. Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy. J. Mol. Cell. Cardiol. 47:664-675. http://dx.doi.org/10.1016/j.yjmcc.2009.08.028.
-
(2009)
J. Mol. Cell. Cardiol.
, vol.47
, pp. 664-675
-
-
Ikeda, H.1
Shiojima, I.2
Ozasa, Y.3
Yoshida, M.4
Holzenberger, M.5
Kahn, C.R.6
Walsh, K.7
Igarashi, T.8
Abel, E.D.9
Komuro, I.10
-
36
-
-
3543008912
-
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte
-
Chan AY, Soltys CL, Young ME, Proud CG, Dyck JR. 2004. Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte. J. Biol. Chem. 279:32771-32779. http://dx.doi.org/10.1074/jbc.M403528200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32771-32779
-
-
Chan, A.Y.1
Soltys, C.L.2
Young, M.E.3
Proud, C.G.4
Dyck, J.R.5
-
37
-
-
0036142957
-
Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes
-
Mauvais-Jarvis F, Ueki K, Fruman DA, Hirshman MF, Sakamoto K, Goodyear LJ, Iannacone M, Accili D, Cantley LC, Kahn CR. 2002. Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes. J. Clin. Invest. 109:141-149. http://dx.doi.org/10.1172/JCI13305.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 141-149
-
-
Mauvais-Jarvis, F.1
Ueki, K.2
Fruman, D.A.3
Hirshman, M.F.4
Sakamoto, K.5
Goodyear, L.J.6
Iannacone, M.7
Accili, D.8
Cantley, L.C.9
Kahn, C.R.10
-
38
-
-
21144446106
-
PGC-1alpha deficiency causes multisystem energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP. 2005. PGC-1alpha deficiency causes multisystem energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol. 3:e101. http://dx.doi.org/10.1371/journal.pbio.0030101.
-
(2005)
PLoS Biol.
, vol.3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
Boudina, S.6
Courtois, M.7
Wozniak, D.F.8
Sambandam, N.9
Bernal-Mizrachi, C.10
Chen, Z.11
Holloszy, J.O.12
Medeiros, D.M.13
Schmidt, R.E.14
Saffitz, J.E.15
Abel, E.D.16
Semenkovich, C.F.17
Kelly, D.P.18
|