Direct large volume injection ultra-high performance liquid chromatography-tandem mass spectrometry determination of artificial sweeteners sucralose and acesulfame in well water

Journal of Chromatography A

Volumn 1359, Issue , 2014, Pages 156-161

  Wu, Minghuo ^a   Qian, Yichao ^a   Boyd, Jessica M ^a   Hrudey, Steve E ^a   Le, X Chris ^a   Li, Xing Fang ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Acesulfame and sucralose; HPLC MS MS; Large volume injection; Sweetener; Wastewater; Well water

Indexed keywords

CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONS; MASS SPECTROMETRY; WASTEWATER;

HPLC-MS/MS; LARGE VOLUME INJECTION; SUCRALOSE; SWEETENER; WELL WATER;

SUGAR SUBSTITUTES;

ACESULFAME; FORMIC ACID; GROUND WATER; SUCRALOSE; WELL WATER;

AQUEOUS SOLUTION; ARTICLE; CANADA; CHEMICAL ANALYSIS; LARGE VOLUME INJECTION; LIMIT OF DETECTION; PRIORITY JOURNAL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WASTE WATER; WATER ANALYSIS; WATER QUALITY;

ACESULFAME AND SUCRALOSE; HPLC-MS/MS; LARGE VOLUME INJECTION; SWEETENER; WASTEWATER; WELL WATER;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FRESH WATER; LIMIT OF DETECTION; MASS SPECTROMETRY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUCROSE; SWEETENING AGENTS; TANDEM MASS SPECTROMETRY; THIAZINES; WATER POLLUTANTS, CHEMICAL;

EID: 84906049772     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.07.035     Document Type: Article

References (25)

1. Grice H.C., Goldsmith L.A. Sucralose-an overview of the toxicity data. Food Chem. Toxicol. 2000, 38:S1-S6.
2. Loos R., Gawlik B.M., Boettcher K., Locoro G., Contini S., Bidoglio G. Sucralose screening in European surface waters using a solid-phase extraction-liquid chromatography-triple quadrupole mass spectrometry method. J. Chromatogr. A 2009, 1216:1126-1131.
3. Swithers S.E. Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements. Trends Endocrinol. Metabolism 2013, 24:431-441.
4. Kokotou M.G., Asimakopoulos A.G., Thomaidis N.S. Artificial sweeteners as emerging pollutants in the environment: analytical methodologies and environmental impact. Anal. Methods 2012, 4:3057-3070.
5. Richardson S.D., Ternes T.A. Water analysis: emerging contaminants and current issues. Anal. Chem. 2014, 86:2813-2848.
6. Lange F.T., Scheurer M., Brauch H.J. Artificial sweeteners-a recently recognized class of emerging environmental contaminants: a review. Anal. Bioanal. Chem. 2012, 403:2503-2518.
7. Buerge I.J., Buser H.R., Kahle M., Muller M.D., Poiger T. Ubiquitous occurrence of the artificial sweetener acesulfame in the aquatic environment: an ideal chemical marker of domestic wastewater in groundwater. Environ. Sci. Technol. 2009, 43:4381-4385.
8. Van Stempvoort D.R., Roy J.W., Brown S.J., Bickerton G. Artificial sweeteners as potential tracers in groundwater in urban environments. J. Hydrol. 2011, 401:126-133.
9. Buerge I.J., Keller M., Buser H.R., Muller M.D., Poiger T. Saccharin and other artificial sweeteners in soils: estimated inputs from agriculture and households, degradation, and leaching to groundwater. Environ. Sci. Technol. 2011, 45:615-621.
10. Scheurer M., Brauch H.J., Lange F.T. Analysis and occurrence of seven artificial sweeteners in German waste water and surface water and in soil aquifer treatment (SAT). Anal. Bioanal. Chem. 2009, 394:1585-1594.
11. Robertson W.D., Van Stempvoort D.R., Solomon D.K., Homewood J., Brown S.J., Spoelstra J., Schiff S.L. Persistence of artificial sweeteners in a 15-year-old septic system plume. J. Hydrol. 2013, 477:43-54.
12. Ordonez E.Y., Quintana J.B., Rodil R., Cela R. Determination of artificial sweeteners in water samples by solid-phase extraction and liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2012, 1256:197-205.
13. Ferrer I., Thurman E.M. Analysis of sucralose and other sweeteners in water and beverage samples by liquid chromatography/time-of-flight mass spectrometry. J. Chromatogr. A 2010, 1217:4127-4134.
14. Gan Z.W., Sun H.W., Wang R.N., Feng B.T. A novel solid-phase extraction for the concentration of sweeteners in water and analysis by ion-pair liquid chromatography-triple quadrupole mass spectrometry. J. Chromatogr. A 2013, 1274:87-96.
15. Berset J.D., Ochsenbein N. Stability considerations of aspartame in the direct analysis of artificial sweeteners in water samples using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Chemosphere 2012, 88:563-569.
16. Qiu W.L., Wang Z.F., Nie W.L., Guo Y.N., Huang L.J. GC-MS determination of sucralose in splenda. Chromatographia 2007, 66:935-939.
17. Morlock G.E., Schuele L., Grashorn S. Development of a quantitative high-performance thin-layer chromatographic method for sucralose in sewage effluent, surface water, and drinking water. J. Chromatogr. A 2011, 1218:2745-2753.
18. Ferrer I., Zweigenbaum J.A., Thurman E.M. Analytical methodologies for the detection of sucralose in water. Anal. Chem. 2013, 85:9581-9587.
19. Minten J., Adolfsson-Erici M., Bjorlenius B., Alsberg T. A method for the analysis of sucralose with electrospray LC/MS in recipient waters and in sewage effluent subjected to tertiary treatment technologies. Int. J. Environ. Anal. Chem. 2011, 91:357-366.
20. Tran N.H., Hu J., Ong S.L. Simultaneous determination of PPCPS, EDCS, and artificial sweeteners in environmental water samples using a single-step SPE coupled with HPLC-MS/MS and isotope dilution. Talanta 2013, 113:82-92.
21. Neset T.S.S., Singer H., Longree P., Bader H.P., Scheidegger R., Wittmer A., Andersson J.C.M. Understanding consumption-related sucralose emissions-a conceptual approach combining substance-flow analysis with sampling analysis. Sci. Total Environ. 2010, 408:3261-3269.
22. Zygler A., Wasik A., Kot-Wasik A., Namiesnik J. Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection. Anal. Bioanal. Chem. 2011, 400:2159-2172.
23. Production of Sucralose without Intermediate Isolation of Crystalline Sucralose-6-Ester, U.S. Patent 5,498,709 A.
24. Backe W.J., Field J.A. Is SPE necessary for environmental analysis? A quantitative comparison of matrix effects from large-volume injection and solid-phase extraction based methods. Environ. Sci. Technol. 2012, 46:6750-6758.
25. Backe W.J., Ort C., Brewer A.J., Field J.A. Analysis of androgenic steroids in environmental waters by large-volume injection liquid chromatography tandem mass spectrometry. Anal. Chem. 2011, 83:2622-2630.