메뉴 건너뛰기




Volumn 189, Issue , 2014, Pages 226-234

The amino acid at residue 155 in nonstructural protein 4 of porcine reproductive and respiratory syndrome virus contributes to its inhibitory effect for interferon-β transcription in vitro

Author keywords

In vitro; Inhibitory effect; Interferon (IFN ); Nonstructural protein 4 (NSP4); Porcine reproductive and respiratory syndrome virus (PRRSV); Transcription

Indexed keywords

AMINO ACID; BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; NONSTRUCTURAL PROTEIN 4; VIRUS PROTEIN;

EID: 84905990372     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2014.05.027     Document Type: Article
Times cited : (25)

References (53)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 0030740903 scopus 로고    scopus 로고
    • Epidemiology of porcine reproductive and respiratory syndrome (PRRS): an overview
    • Albina E. Epidemiology of porcine reproductive and respiratory syndrome (PRRS): an overview. Vet. Microbiol. 1997, 55:309-316.
    • (1997) Vet. Microbiol. , vol.55 , pp. 309-316
    • Albina, E.1
  • 3
    • 0026455718 scopus 로고
    • Report on the first outbreaks of the porcine reproductive and respiratory syndrome (PRRS) in France. Diagnosis and viral isolation
    • Baron T., Albina E., Leforban Y., Madec F., Guilmoto H., Plana Duran J., Vannier P. Report on the first outbreaks of the porcine reproductive and respiratory syndrome (PRRS) in France. Diagnosis and viral isolation. Ann. Rech. Vet. 1992, 23:161-166.
    • (1992) Ann. Rech. Vet. , vol.23 , pp. 161-166
    • Baron, T.1    Albina, E.2    Leforban, Y.3    Madec, F.4    Guilmoto, H.5    Plana Duran, J.6    Vannier, P.7
  • 5
    • 73949087536 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activation
    • Beura L.K., Sarkar S.N., Kwon B., Subramaniam S., Jones C., Pattnaik A.K., Osorio F.A. Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activation. J. Virol. 2010, 84:1574-1584.
    • (2010) J. Virol. , vol.84 , pp. 1574-1584
    • Beura, L.K.1    Sarkar, S.N.2    Kwon, B.3    Subramaniam, S.4    Jones, C.5    Pattnaik, A.K.6    Osorio, F.A.7
  • 6
    • 0028071817 scopus 로고
    • Isolation of porcine reproductive and respiratory syndrome (PRRS) virus in a Danish swine herd and experimental infection of pregnant gilts with the virus
    • Botner A., Nielsen J., Bille-Hansen V. Isolation of porcine reproductive and respiratory syndrome (PRRS) virus in a Danish swine herd and experimental infection of pregnant gilts with the virus. Vet. Microbiol. 1994, 40:351-360.
    • (1994) Vet. Microbiol. , vol.40 , pp. 351-360
    • Botner, A.1    Nielsen, J.2    Bille-Hansen, V.3
  • 7
    • 56749133272 scopus 로고    scopus 로고
    • Viral evasion and subversion of pattern-recognition receptor signalling
    • Bowie A.G., Unterholzner L. Viral evasion and subversion of pattern-recognition receptor signalling. Nat. Rev. Immunol. 2008, 8:911-922.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 911-922
    • Bowie, A.G.1    Unterholzner, L.2
  • 8
    • 0030634897 scopus 로고    scopus 로고
    • Nidovirales: a new order comprising Coronaviridae and Arteriviridae
    • Cavanagh D. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 1997, 142:629-633.
    • (1997) Arch. Virol. , vol.142 , pp. 629-633
    • Cavanagh, D.1
  • 9
    • 47549094091 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages
    • Costers S., Lefebvre D.J., Delputte P.L., Nauwynck H.J. Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages. Arch. Virol. 2008, 153:1453-1465.
    • (2008) Arch. Virol. , vol.153 , pp. 1453-1465
    • Costers, S.1    Lefebvre, D.J.2    Delputte, P.L.3    Nauwynck, H.J.4
  • 10
    • 18844414172 scopus 로고
    • Quebec. Isolation of the porcine reproductive and respiratory syndrome virus in Quebec
    • Dea S., Bilodeau R., Athanassious R., Sauvageau R.A., Martineau G.P. Quebec. Isolation of the porcine reproductive and respiratory syndrome virus in Quebec. Can. Vet. J. 1992, 33:552-553.
    • (1992) Can. Vet. J. , vol.33 , pp. 552-553
    • Dea, S.1    Bilodeau, R.2    Athanassious, R.3    Sauvageau, R.A.4    Martineau, G.P.5
  • 11
    • 0025949412 scopus 로고
    • Nuclear targeting sequences-a consensus?
    • Dingwall C., Laskey R.A. Nuclear targeting sequences-a consensus?. Trends Biochem. Sci. 1991, 16:478-481.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 478-481
    • Dingwall, C.1    Laskey, R.A.2
  • 12
    • 78649326444 scopus 로고    scopus 로고
    • The structural biology of PRRSV
    • Dokland T. The structural biology of PRRSV. Virus Res. 2010, 154:86-97.
    • (2010) Virus Res. , vol.154 , pp. 86-97
    • Dokland, T.1
  • 13
    • 0029643342 scopus 로고
    • Porcine reproductive and respiratory syndrome: clinical disease, pathology and immunosuppression
    • Done S.H., Paton D.J. Porcine reproductive and respiratory syndrome: clinical disease, pathology and immunosuppression. Vet. Rec. 1995, 136:32-35.
    • (1995) Vet. Rec. , vol.136 , pp. 32-35
    • Done, S.H.1    Paton, D.J.2
  • 14
    • 84862160840 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus nonstructural protein 2 contributes to NF-κB activation
    • Fang Y., Fang L., Wang Y., Lei Y., Luo R., Wang D., Chen H., Xiao S. Porcine reproductive and respiratory syndrome virus nonstructural protein 2 contributes to NF-κB activation. Virol. J. 2012, 9:83-92.
    • (2012) Virol. J. , vol.9 , pp. 83-92
    • Fang, Y.1    Fang, L.2    Wang, Y.3    Lei, Y.4    Luo, R.5    Wang, D.6    Chen, H.7    Xiao, S.8
  • 15
    • 0035027520 scopus 로고    scopus 로고
    • In utero infection by porcine reproductive and respiratory syndrome virus is sufficient to increase susceptibility of piglets to challenge by Streptococcus suis type II
    • Feng W., Laster S.M., Tompkins M., Brown T., Xu J.S., Altier C., Gomez W., Benfield D., McCaw M.B. In utero infection by porcine reproductive and respiratory syndrome virus is sufficient to increase susceptibility of piglets to challenge by Streptococcus suis type II. J. Virol. 2001, 75:4889-4895.
    • (2001) J. Virol. , vol.75 , pp. 4889-4895
    • Feng, W.1    Laster, S.M.2    Tompkins, M.3    Brown, T.4    Xu, J.S.5    Altier, C.6    Gomez, W.7    Benfield, D.8    McCaw, M.B.9
  • 16
    • 84870199424 scopus 로고    scopus 로고
    • NF-kappaB as a target for modulating inflammatory responses
    • Gasparini C., Feldmann M. NF-kappaB as a target for modulating inflammatory responses. Curr. Pharm. Des. 2012, 18:5735-5745.
    • (2012) Curr. Pharm. Des. , vol.18 , pp. 5735-5745
    • Gasparini, C.1    Feldmann, M.2
  • 17
    • 84894276741 scopus 로고    scopus 로고
    • Highly pathogenic porcine reproductive and respiratory syndrome virus infection results in acute lung injury of the infected pigs
    • Han D., Hu Y., Li L., Tian H., Chen Z., Wang L., Ma H., Yang H., Teng K. Highly pathogenic porcine reproductive and respiratory syndrome virus infection results in acute lung injury of the infected pigs. Vet. Microbiol. 2014, 169:135-146.
    • (2014) Vet. Microbiol. , vol.169 , pp. 135-146
    • Han, D.1    Hu, Y.2    Li, L.3    Tian, H.4    Chen, Z.5    Wang, L.6    Ma, H.7    Yang, H.8    Teng, K.9
  • 18
    • 79955574664 scopus 로고    scopus 로고
    • Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses
    • Johnson C.R., Griggs T.F., Gnanandarajah J., Murtaugh M.P. Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses. J. Gen. Virol. 2011, 92:1107-1116.
    • (2011) J. Gen. Virol. , vol.92 , pp. 1107-1116
    • Johnson, C.R.1    Griggs, T.F.2    Gnanandarajah, J.3    Murtaugh, M.P.4
  • 19
    • 77955487727 scopus 로고    scopus 로고
    • Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate
    • Karniychuk U.U., Geldhof M., Vanhee M., Van Doorsselaere J., Saveleva T.A., Nauwynck H.J. Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate. BMC Vet. Res. 2010, 6:30-39.
    • (2010) BMC Vet. Res. , vol.6 , pp. 30-39
    • Karniychuk, U.U.1    Geldhof, M.2    Vanhee, M.3    Van Doorsselaere, J.4    Saveleva, T.A.5    Nauwynck, H.J.6
  • 22
    • 0002628643 scopus 로고
    • Reproductive failure of unknown etiology
    • Keffaber K. Reproductive failure of unknown etiology. Am. Assoc. Swine Prac. News 1989, 1:9.
    • (1989) Am. Assoc. Swine Prac. News , vol.1 , pp. 9
    • Keffaber, K.1
  • 23
    • 77953028825 scopus 로고    scopus 로고
    • Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells
    • Kim O., Sun Y., Lai F.W., Song C., Yoo D. Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells. Virology 2010, 402:315-326.
    • (2010) Virology , vol.402 , pp. 315-326
    • Kim, O.1    Sun, Y.2    Lai, F.W.3    Song, C.4    Yoo, D.5
  • 24
    • 0028523907 scopus 로고
    • An outbreak of porcine reproductive and respiratory syndrome in Japan
    • Kuwahara H., Nunoya T., Tajima M., Kato A., Samejima T. An outbreak of porcine reproductive and respiratory syndrome in Japan. J. Vet. Med. Sci. 1994, 56:901-909.
    • (1994) J. Vet. Med. Sci. , vol.56 , pp. 901-909
    • Kuwahara, H.1    Nunoya, T.2    Tajima, M.3    Kato, A.4    Samejima, T.5
  • 25
    • 32844468079 scopus 로고    scopus 로고
    • Mutations within the nuclear localization signal of the porcine reproductive and respiratory syndrome virus nucleocapsid protein attenuate virus replication
    • Lee C., Hodgins D., Calver t J.G., Welch S.K., Jolie R., Yoo D. Mutations within the nuclear localization signal of the porcine reproductive and respiratory syndrome virus nucleocapsid protein attenuate virus replication. Virology 2006, 346:238-250.
    • (2006) Virology , vol.346 , pp. 238-250
    • Lee, C.1    Hodgins, D.2    Calver t, J.G.3    Welch, S.K.4    Jolie, R.5    Yoo, D.6
  • 26
    • 84866178057 scopus 로고    scopus 로고
    • Chinese highly pathogenic porcine reproductive and respiratory syndrome virus exhibits more extensive tissue tropism for pigs
    • Li L., Zhao Q., Ge X., Teng K., Kuang Y., Chen Y., Guo X., Yang H. Chinese highly pathogenic porcine reproductive and respiratory syndrome virus exhibits more extensive tissue tropism for pigs. Virol. J. 2012, 9:203-208.
    • (2012) Virol. J. , vol.9 , pp. 203-208
    • Li, L.1    Zhao, Q.2    Ge, X.3    Teng, K.4    Kuang, Y.5    Chen, Y.6    Guo, X.7    Yang, H.8
  • 27
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q., Verma I.M. NF-kappaB regulation in the immune system. Nat. Rev. Immunol. 2002, 2:725-734.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 28
    • 41849125938 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses interferon-beta production by interfering with the RIG-I signaling pathway
    • Luo R., Xiao S., Jiang Y., Jin H., Wang D., Liu M., Chen H., Fang L. Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses interferon-beta production by interfering with the RIG-I signaling pathway. Mol. Immunol. 2008, 45:2839-2846.
    • (2008) Mol. Immunol. , vol.45 , pp. 2839-2846
    • Luo, R.1    Xiao, S.2    Jiang, Y.3    Jin, H.4    Wang, D.5    Liu, M.6    Chen, H.7    Fang, L.8
  • 29
    • 84880708211 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus nonstructural protein 4 induces apoptosis dependent on its 3C-like serine protease activity
    • Ma Z., Wang Y., Zhao H., Xu A.T., Tang J., Feng W.H. Porcine reproductive and respiratory syndrome virus nonstructural protein 4 induces apoptosis dependent on its 3C-like serine protease activity. PLoS One 2013, 8(7):e69387.
    • (2013) PLoS One , vol.8 , Issue.7
    • Ma, Z.1    Wang, Y.2    Zhao, H.3    Xu, A.T.4    Tang, J.5    Feng, W.H.6
  • 30
    • 46149122330 scopus 로고    scopus 로고
    • The challenge of PRRS immunology
    • Mateu E., Diaz I. The challenge of PRRS immunology. Vet. J. 2008, 177:345-351.
    • (2008) Vet. J. , vol.177 , pp. 345-351
    • Mateu, E.1    Diaz, I.2
  • 31
    • 7044286680 scopus 로고    scopus 로고
    • Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cells
    • Miller L.C., Laegreid W.W., Bono J.L., Chitko-McKown C.G., Fox J.M. Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cells. Arch. Virol. 2004, 149:2453-2463.
    • (2004) Arch. Virol. , vol.149 , pp. 2453-2463
    • Miller, L.C.1    Laegreid, W.W.2    Bono, J.L.3    Chitko-McKown, C.G.4    Fox, J.M.5
  • 33
    • 0032889516 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents
    • Nelsen C.J., Murtaugh M.P., Faaberg K.S. Porcine reproductive and respiratory syndrome virus comparison: divergent evolution on two continents. J. Virol. 1999, 73:270-280.
    • (1999) J. Virol. , vol.73 , pp. 270-280
    • Nelsen, C.J.1    Murtaugh, M.P.2    Faaberg, K.S.3
  • 34
    • 44349146579 scopus 로고    scopus 로고
    • Functional mapping of the porcine reproductive and respiratory syndrome virus capsid protein nuclear localization signal and its pathogenic association
    • Pei Y., Hodgins D.C., Lee C., Calvert J.G., Welch S.K., Jolie R., Keith M., Yoo D. Functional mapping of the porcine reproductive and respiratory syndrome virus capsid protein nuclear localization signal and its pathogenic association. Virus Res. 2008, 135:107-114.
    • (2008) Virus Res. , vol.135 , pp. 107-114
    • Pei, Y.1    Hodgins, D.C.2    Lee, C.3    Calvert, J.G.4    Welch, S.K.5    Jolie, R.6    Keith, M.7    Yoo, D.8
  • 35
    • 36348940608 scopus 로고    scopus 로고
    • Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures
    • Randall R.E., Goodbourn S. Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J. Gen. Virol. 2008, 89:1-47.
    • (2008) J. Gen. Virol. , vol.89 , pp. 1-47
    • Randall, R.E.1    Goodbourn, S.2
  • 36
    • 0031611502 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome
    • Rossow K.D. Porcine reproductive and respiratory syndrome. Vet. Pathol. 1998, 35:1-20.
    • (1998) Vet. Pathol. , vol.35 , pp. 1-20
    • Rossow, K.D.1
  • 37
    • 0032842312 scopus 로고    scopus 로고
    • The localization of porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus of infected cells and identification of a potential nucleolar localization signal sequence
    • Rowland R.R., Kervin R., Kuckleburg C., Sperlich A., Benfield D.A. The localization of porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus of infected cells and identification of a potential nucleolar localization signal sequence. Virus Res. 1999, 64:1-12.
    • (1999) Virus Res. , vol.64 , pp. 1-12
    • Rowland, R.R.1    Kervin, R.2    Kuckleburg, C.3    Sperlich, A.4    Benfield, D.A.5
  • 38
    • 82455167225 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus nucleocapsid protein modulates interferon-beta production by inhibiting IRF3 activation in immortalized porcine alveolar macrophages
    • Sagong M., Lee C. Porcine reproductive and respiratory syndrome virus nucleocapsid protein modulates interferon-beta production by inhibiting IRF3 activation in immortalized porcine alveolar macrophages. Arch. Virol. 2011, 156:2187-2195.
    • (2011) Arch. Virol. , vol.156 , pp. 2187-2195
    • Sagong, M.1    Lee, C.2
  • 39
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
    • Seth R.B., Sun L., Ea C.K., Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005, 122:669-682.
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 40
    • 79957805839 scopus 로고    scopus 로고
    • Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-beta induction
    • Shi X., Wang L., Li X., Zhang G., Guo J., Zhao D., Chai S., Deng R. Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-beta induction. Mol. Immunol. 2011, 48:1568-1572.
    • (2011) Mol. Immunol. , vol.48 , pp. 1568-1572
    • Shi, X.1    Wang, L.2    Li, X.3    Zhang, G.4    Guo, J.5    Zhao, D.6    Chai, S.7    Deng, R.8
  • 41
    • 79958224016 scopus 로고    scopus 로고
    • The nonstructural protein 1 papain-like cysteine protease was necessary for porcine reproductive and respiratory syndrome virus nonstructural protein 1 to inhibit interferon-beta induction
    • Shi X., Zhang G., Wang L., Li X., Zhi Y., Wang F., Fan J., Deng R. The nonstructural protein 1 papain-like cysteine protease was necessary for porcine reproductive and respiratory syndrome virus nonstructural protein 1 to inhibit interferon-beta induction. DNA Cell Biol. 2011, 30:355-362.
    • (2011) DNA Cell Biol. , vol.30 , pp. 355-362
    • Shi, X.1    Zhang, G.2    Wang, L.3    Li, X.4    Zhi, Y.5    Wang, F.6    Fan, J.7    Deng, R.8
  • 42
    • 77957674435 scopus 로고    scopus 로고
    • Nonstructural protein 1alpha subunit-based inhibition of NF-kappaB activation and suppression of interferon-beta production by porcine reproductive and respiratory syndrome virus
    • Song C., Krell P., Yoo D. Nonstructural protein 1alpha subunit-based inhibition of NF-kappaB activation and suppression of interferon-beta production by porcine reproductive and respiratory syndrome virus. Virology 2010, 407:268-280.
    • (2010) Virology , vol.407 , pp. 268-280
    • Song, C.1    Krell, P.2    Yoo, D.3
  • 43
    • 84860235854 scopus 로고    scopus 로고
    • Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus
    • Sun Y., Han M., Kim C., Calvert J.G., Yoo D. Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus. Viruses 2012, 4:424-446.
    • (2012) Viruses , vol.4 , pp. 424-446
    • Sun, Y.1    Han, M.2    Kim, C.3    Calvert, J.G.4    Yoo, D.5
  • 44
    • 77954461006 scopus 로고    scopus 로고
    • The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functions
    • Sun Z., Chen Z., Lawson S.R., Fang Y. The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functions. J. Virol. 2010, 84:7832-7846.
    • (2010) J. Virol. , vol.84 , pp. 7832-7846
    • Sun, Z.1    Chen, Z.2    Lawson, S.R.3    Fang, Y.4
  • 46
    • 69749102863 scopus 로고    scopus 로고
    • Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
    • Tian X., Lu G., Gao F., Peng H., Feng Y., Ma G., Bartlam M., Tian K., Yan J., Hilgenfeld R., Gao G.F. Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). J. Mol. Biol. 2009, 392:977-993.
    • (2009) J. Mol. Biol. , vol.392 , pp. 977-993
    • Tian, X.1    Lu, G.2    Gao, F.3    Peng, H.4    Feng, Y.5    Ma, G.6    Bartlam, M.7    Tian, K.8    Yan, J.9    Hilgenfeld, R.10    Gao, G.F.11
  • 47
    • 33645220757 scopus 로고    scopus 로고
    • Mutagenesis analysis of the nsp4 main proteinase reveals determinants of arterivirus replicase polyprotein autoprocessing
    • van Aken D., Snijder E.J., Gorbalenya A.E. Mutagenesis analysis of the nsp4 main proteinase reveals determinants of arterivirus replicase polyprotein autoprocessing. J. Virol. 2006, 80:3428-3437.
    • (2006) J. Virol. , vol.80 , pp. 3428-3437
    • van Aken, D.1    Snijder, E.J.2    Gorbalenya, A.E.3
  • 48
    • 33751405956 scopus 로고    scopus 로고
    • Proteolytic maturation of replicase polyprotein pp1a by the nsp4 main proteinase is essential for equine arteritis virus replication and includes internal cleavage of nsp7
    • van Aken D., Zevenhoven-Dobbe J., Gorbalenya A.E., Snijder E.J. Proteolytic maturation of replicase polyprotein pp1a by the nsp4 main proteinase is essential for equine arteritis virus replication and includes internal cleavage of nsp7. J. Gen. Virol. 2006, 87:3473-3482.
    • (2006) J. Gen. Virol. , vol.87 , pp. 3473-3482
    • van Aken, D.1    Zevenhoven-Dobbe, J.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 49
    • 0032982143 scopus 로고    scopus 로고
    • Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and Is essential for virus replication
    • van Dinten L.C., Rensen S., Gorbalenya A.E., Snijder E.J. Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and Is essential for virus replication. J. Virol. 1999, 73:2027-2037.
    • (1999) J. Virol. , vol.73 , pp. 2027-2037
    • van Dinten, L.C.1    Rensen, S.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 51
    • 78649288595 scopus 로고    scopus 로고
    • Modulation of host cell responses and evasion strategies for porcine reproductive and respiratory syndrome virus
    • Yoo D., Song C., Sun Y., Du Y., Kim O., Liu H.C. Modulation of host cell responses and evasion strategies for porcine reproductive and respiratory syndrome virus. Virus Res. 2010, 154:48-60.
    • (2010) Virus Res. , vol.154 , pp. 48-60
    • Yoo, D.1    Song, C.2    Sun, Y.3    Du, Y.4    Kim, O.5    Liu, H.C.6
  • 52
    • 78649317975 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome in China
    • Zhou L., Yang H. Porcine reproductive and respiratory syndrome in China. Virus Res. 2010, 154:31-37.
    • (2010) Virus Res. , vol.154 , pp. 31-37
    • Zhou, L.1    Yang, H.2
  • 53
    • 65349102181 scopus 로고    scopus 로고
    • The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence
    • Zhou L., Zhang J., Zeng J., Yin S., Li Y., Zheng L., Guo X., Ge X., Yang H. The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence. J. Virol. 2009, 83:5156-5167.
    • (2009) J. Virol. , vol.83 , pp. 5156-5167
    • Zhou, L.1    Zhang, J.2    Zeng, J.3    Yin, S.4    Li, Y.5    Zheng, L.6    Guo, X.7    Ge, X.8    Yang, H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.