Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate

BMC Veterinary Research

Volumn 6, Issue , 2010, Pages

  Karniychuk, Uladzimir U ^a   Geldhof, Marc ^a   Vanhee, Merijn ^a   Van Doorsselaere, Jan ^b   Saveleva, Tamara A ^c   Nauwynck, Hans J ^a  

^a GHENT UNIVERSITY   (Belgium)

^b Katholieke Hogeschool Zuid West Vlaanderen   (Belgium)

^c Institute of Experimental Veterinary Medicine   (Belarus)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; ARCANOBACTERIUM PYOGENES; ARTERIVIRUS; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; STREPTOCOCCUS SUIS; SUIDAE;

VIRUS ANTIBODY; VIRUS ANTIGEN;

ANIMAL; ANTIBODY SPECIFICITY; ARTERIVIRUS; ARTICLE; BELARUS; BLOOD; IMMUNOLOGY; PATHOGENICITY; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; SWINE; VIROLOGY;

ANIMALS; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; ANTIGENS, VIRAL; BYELARUS; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SWINE;

EID: 77955487727     PISSN: None     EISSN: 17466148     Source Type: Journal    
DOI: 10.1186/1746-6148-6-30     Document Type: Article

References (32)

1. Keffaber KK. Reproductive failure of unknown etiology. Am Assoc Swine Pract Newsl 1989, 1:1-10.
2. White M. Letter to the editor "Blue ear" disease of pigs. Vet Rec 1991, 128:574.
3. Snijder EJ, Meulenberg JJM. The molecular biology of arteriviruses. J Gen Virol 1998, 79:961-979.
4. Dea S, Gagnon CA, Mardassi H, Pirzadeh B, Rogan D. Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: comparison of the North American and European isolates. Arch Virol 2000, 145:659-688. 10.1007/s007050050662, 10893147.
5. Meulenberg JJM, Besten DA. Identification and characterization of a sixth structural protein of Lelystad Virus: the glycoprotein GP2 encoded by ORF2 is incorporated in virus particle. Virol 1996, 225:44-51.
6. Andreyev VG, Wesley RD, Mengeling WL, Vorwald AC, Lager KM. Genetic variation and phylogenetic relationships of 22 porcine reproductive and respiratory syndrome virus (PRRSV) field strains based on sequence analysis of open reading frame 5. Arch Virol 1997, 142:993-1001. 10.1007/s007050050134, 9191863.
7. Kapur V, Elam MR, Pawlovich TM, Murtaugh MP. Genetic variation in porcine reproductive and respiratory syndrome virus isolates in the midwestern United States. J Gen Virolo 1996, 77:1271-1276.
8. Frey M, Eernisse K, Landgraf J, Pearson J, Chladek D. Diagnostic testing for SIRS virus at the National Veterinary Service Laboratory (NVSL). Am Assoc Swine 1992, 4:31.
9. Wensvoort G, de Kluyver EP, Luijtze EA, Besten DA, Harris L, Collins JE, Christianson WT, Chladek D. Antigenic comparison of Lelystad virus and swine infertility and respiratory syndrome (SIRS) virus. J Vet Diagn Invest 1992, 4:134-138.
10. Wieczorek-Krohmer M, Weiland F, Conzelmann K, Kohl D, Visser N, Van Woensel P, Thiel HJ, Weiland E. Porcine reproductive and respiratory syndrome virus (PRRSV): monoclonal antibodies detect common epitopes on two viral proteins of European and U.S. isolates. Vet Microbiol 1996, 51:257-266. 10.1016/0378-1135(96)00047-8, 8870188.
11. Mardassi H, Mounir S, Dea S. Identification of major differences in the nucleocapsid protein genes of a Québec strain and European strains of porcine reproductive and respiratory syndrome virus. J Gen Virol 1994, 75:681-685. 10.1099/0022-1317-75-3-681, 8126467.
12. Stadejek T, Oleksiewicz MB, Potapchuk D, Podgorska K. Porcine reproductive and respiratory syndrome virus strains of exceptional diversity in Eastern Europe support the definition of new genetic subtypes. J Gen Virol 2006, 87:1835-1841. 10.1099/vir.0.81782-0, 16760385.
13. Stadejek T, Oleksiewicz MB, Scherbakov AV, Timina AM, Krabbe JS, Chabros K, Potapchuk D. Definition of subtypes in the European genotype of porcine reproductive and respiratory syndrome virus: nucleocapsid characteristics and geographical distribution in Europe. Arch Virol 2008, 153:1479-1488. 10.1007/s00705-008-0146-2, 18592131.
14. Johnson W, Roof M, Vaughn E, Christopher-Hennings J, Johnson CR, Murtaugh MP. Pathogenic and humoral immune responses to porcine reproductive and respiratory syndrome virus (PRRSV) are related to viral load in acute infection. Vet Immunol Immunopathol 2004, 102:233-247. 10.1016/j.vetimm.2004.09.010, 15507308.
15. Rossow KD, Bautista EM, Goyal SM, Molitor TW, Murtaugh MP, Morrison RB, Benfield DA, Collins JE. Experimental porcine reproductive and respiratory syndrome virus infection in one-, four-, and 10-week-old pigs. J Vet Diagn Invest 1994, 6:3-12.
16. Lopez OJ, Oliveira MF, Alvarez Garcia E, Kwon BJ, Doster A, FA Osorio FA. Protection against porcine reproductive and respiratory syndrome virus (PRRSV) infection through passive transfer of PRRSV-neutralizing antibodies is dose dependent. Clin Vaccine Immunol 2007, 14:269-275. 10.1128/CVI.00304-06, 1828847, 17215336.
17. Truong HM, Lu Z, Kutish GF, Galeota J, Osorio FA, Pattnaik AK. A highly pathogenic porcine reproductive and respiratory syndrome virus generated from an infectious cDNA clone retains the in vivo virulence and transmissibility properties of the parental virus. Virology 2004, 325:308-319. 10.1016/j.virol.2004.04.046, 15246270.
18. Lohsel L, Nielsen J, Eriksen L. Temporary CD8+ T-Cell depletion in pigs does not exacerbate infection with porcine reproductive and respiratory syndrome virus (PRRSV). Viral Immunol 2004, 17:594-603. 10.1089/vim.2004.17.594, 15671757.
19. Martelli P, Cordioli P, Alborali LG, Gozio S, De Angelis E, Ferrari L, Lombardi G, Borghetti P. Protection and immune response in pigs intradermally vaccinated against porcine reproductive and respiratory syndrome (PRRS) and subsequently exposed to a heterologous European (Italian cluster) field strain. Vaccine 2007, 25:3400-3408. 10.1016/j.vaccine.2006.12.050, 17276558.
20. Thanawongnuwech R, Brown GB, Halbur PG, Roth JA, Royer RL, Thacker BJ. Pathogenesis of porcine reproductive and respiratory syndrome virus-induced increase in susceptibility to Streptococcus suis infection. Vet Pathol 2000, 37:143-152. 10.1354/vp.37-2-143, 10714643.
21. Galina L, Pijoan C, Sitjar M, Christianson WT, Rossow K, Collins JE. Interaction between Streptococcus suis serotype 2 and porcine reproductive and respiratory syndrome virus in specific pathogen-free piglets. Vet Rec 1994, 134:60-64.
22. Chitko-McKown CG, Blecha F. Pulmonary intravascular macrophages: a review of immune properties and functions. Ann Rech Vet 1992, 23:201-214.
23. Thanawongnuwech R, Brown GB, Halbur PG, Roth JA, Royer RL, Thacker BJ. Pathogenesis of porcine reproductive and respiratory syndrome virus-induced increase in susceptibility to Streptococcus suis infection. Vet Pathol 2000, 37:143-152. 10.1354/vp.37-2-143, 10714643.
24. Thanawongnuwech R, Halbur PG, Ackermann MR, Thacker EL, Royer RL. Effects of low (modified-live virus vaccine) and high (VR-2385)-virulence strains of porcine reproductive and respiratory syndrome virus on pulmonary clearance of copper particles in pigs. Vet Pathol 1998, 35:398-406. 10.1177/030098589803500509, 9754545.
25. Thanawongnuwech R, Thacker EL, Halbur PG. Effect of porcine reproductive and respiratory syndrome virus (PRRSV) (isolate ATCC VR-2385) infection on bactericidal activity of porcine pulmonary intravascular macrophages (PIMs): in vitro comparisons with pulmonary alveolar macrophages (PAMs). Vet Immunol Immunopathol 1997, 59:323-335. 10.1016/S0165-2427(97)00078-0, 9477481.
26. Thanawongnuwech R, Thacker EL, Halbur PG. Influence of pig age on virus titer and bactericidal activity of porcine reproductive and respiratory syndrome virus (PRRSV)-infected pulmonary intravascular macrophages (PIMs). Vet Microbiol 1998, 63:177-187. 10.1016/S0378-1135(98)00245-4, 9850997.
27. Feng Y, Zhao T, Nguyen T, Inui K, Ma Y, Nguyen TH, Nguyen VC, Liu D, Bui QA, To LT, Wang C, Tian K, Gao GF. Porcine respiratory and reproductive syndrome virus variants, Vietnam and China, 2007. Emerg Infect Dis 2008, 14:1774-1776. 10.3201/eid1411.071676, 2630730, 18976568.
28. Wensvoort G, Terpstra C, Pol JMA, ter Laak EA, Bloemraad M, de Kluyver EP, Kragten C, van Buiten L, den Besten A, Wagenaar F, Broekhuijsen JM, Moonen PLJM, Zetstra T, de Boer EA, Tibben HJ, de Jong MF, van 't Veld P, Groenland GJR, van Gennep JA, Voets M, Verheijden JHM, Braamskamp J. Mystery swine disease in the Netherlands: the isolation of the Lelystad virus. Vet Q 1991, 13:121-130.
29. Duan X, Nauwynck HJ, Pensaert MB. Virus quantification and identification of cellular targets in the lungs and lymphoid tissues of pigs at different time intervals after inoculation with porcine reproductive and respiratory syndrome virus (PRRSV). Vet Microbiol 1997, 56:9-19. 10.1016/S0378-1135(96)01347-8, 9228678.
30. Costers S, Lefebvre DJ, Goddeeris B, Delputte PL, Nauwynck HJ. Functional impairment of PRRSV-specific peripheral CD3+CD8high cells. Vet Res 2009, 40:46. 10.1051/vetres/2009029, 2701180, 19445889.
31. Labarque GG, Nauwynck HJ, Van Reeth K, Pensaert MB. Effect of cellular changes and onset of humoral immunity on the replication of porcine reproductive and respiratory syndrome virus in the lungs of pigs. J Gen Virol 2000, 81:1327-1334.
32. Quinn PJ, Carter ME, Markey BK, Carter GR. Clinical Veterinary Microbiology. Mosby, Edinburgh 1994, 254-259.