The ability to rearrange dual TCRs enhances positive selection, leading to increased allo- and autoreactive T cell repertoires

Journal of Immunology

Volumn 193, Issue 4, 2014, Pages 1778-1786

  Ni, Peggy P ^a   Solomon, Benjamin ^a   Hsieh, Chyi Song ^a   Allen, Paul M ^a   Morris, Gerald P ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; AUTOANTIGEN; CD22 ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ALLOREACTIVE T LYMPHOCYTE; AMINO ACID SEQUENCE; ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; AUTOREACTIVE T LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CELL CULTURE; CELL MATURATION; CELL SELECTION; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; HETEROZYGOSITY; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; T LYMPHOCYTE; THYMOCYTE;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CHO CELLS; CRICETULUS; GENETIC VARIATION; GRAFT VS HOST DISEASE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTE SUBSETS; THYMOCYTES;

EID: 84905990186     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400532     Document Type: Article

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