Transport in Caco-2 Cell monolayers of antidiabetic cucurbitane triterpenoids from Momordica charantia fruits

Planta Medica

Volumn 80, Issue 11, 2014, Pages 907-911

  Wu, Shi Biao ^a   Yue, Grace G L ^b   To, Ming Ho ^b   Keller, Amy C ^a   Lau, Clara B S ^b   Kennelly, Edward J ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

bitter melon; Caco 2 cells; Cucurbitaceae; cucurbitane triterpenoid; diabetes treatments; Momordica charantia

Indexed keywords

3 BETA 7 BETA 25 TRIHYDROXYCUCURBITA 5,23 DIEN 19 AL; 3 HYDROXYCUCURBITA 5,24 DIEN 19 AL 7,23 DI O BETA GLUCOPYRANOSIDE; 3 O BETA DEXTRO ALLO PYRANOSYL 7BETA,25 DIHYDROXYCUCURBITA 5,23 DIEN 19 AL; ANTIDIABETIC AGENT; ATENOLOL; BUTANOL; CUCURBITANE TRITERPENOID; GOYAGLYCOSIDE E; GOYAGLYCOSIDE F; KUGUAGLYCOSIDE E; MOMORDICA CHARANTIA EXTRACT; MOMORDICINE I; MOMORDICINE II; MOMORDICOSIDE F2; MOMORDICOSIDE L; MOMORDICOSIDE X; PROPRANOLOL; TRITERPENOID; UNCLASSIFIED DRUG; CUCURBITANE; GLYCOSIDE; STEROL; TRITERPENE;

ANTIDIABETIC ACTIVITY; ARTICLE; CACO 2 CELL LINE; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PENETRATION; DRUG STRUCTURE; DRUG TRANSPORT; FRUIT; GASTROINTESTINAL TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN RELEASE; INTESTINE EPITHELIUM CELL; MOMORDICA CHARANTIA; MONOLAYER CULTURE; TIME OF FLIGHT MASS SPECTROMETRY; CHEMISTRY; DIABETES MELLITUS; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; MEDICINAL PLANT; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIABETES MELLITUS; FRUIT; GLYCOSIDES; HUMANS; HYPOGLYCEMIC AGENTS; MASS SPECTROMETRY; MOMORDICA CHARANTIA; PLANTS, MEDICINAL; STEROLS; TRITERPENES;

EID: 84905983584     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1382837     Document Type: Article

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