Role of polymorphonuclear leukocyte infiltration in the mechanism of anti-inflammatory effect of amiodarone

Pharmacological Reports

Volumn 59, Issue 5, 2007, Pages 538-544

  Ozbakis Dengiz, Gunnur ^a   Halici, Zekai ^b   Akpinar, Erol ^c   Cadirci, Elif ^b   Bilici, Dilek ^b   Gursan, Nesrin ^b  

^a Zonguldak Karaelmas Universitesi Tip Fakultesi   (Turkey)

^b ATATURK UNIVERSITY   (Turkey)

^c Hospital of Respiratory Diseases   (Turkey)

Author keywords

Amiodarone; Histamine; Inflammation; Polymorphonuclear leukocytes; Rat

Indexed keywords

AMIODARONE; CALCIUM CHANNEL; DICLOFENAC; FREE RADICAL; HISTAMINE; NITRIC OXIDE; PHOSPHOLIPASE A2; PROTEINASE; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MOTION; CHANNEL GATING; CONTROLLED STUDY; DECAPITATION; DOSE RESPONSE; DRUG DOSE COMPARISON; ENZYME INHIBITION; ENZYME RELEASE; HISTOPATHOLOGY; LEUKOCYTE ACTIVATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PAW EDEMA; PLETHYSMOGRAPHY; RAT; TIME; TREATMENT OUTCOME;

EID: 38049169562     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Abramson SR, Weissmann G: The mechanisms of action of nonsteroidal antiinflammatory drugs. Arthritis Rheum, 1989, 32, 1-9.
2. Aditya GN, Chattopadhya RN, Mandal S: Preliminary study on anti-inflamatory effect of calcium channel blockers in albino rats. Indian J Pharmacol, 1997, 29, 132-134.
3. Azuma Y, Tokunaga T, Takeda Y, Ogawa T, Takagi N: The effect of calcium antagonists on the activation of guinea pig neutrophils. Jpn J Pharmacol, 1986, 42, 243-251.
4. Babior BM, Kipnes RS, Curnutte JT: The production by leucocytes of superoxide, a potential bactericidal agent. J Clin Invest, 1973, 5, 741-744.
5. Benbarek H, Mouithys-Mickalad A, Deby-Dupont G, Deby C, Grulke S, Nemmar A, Lamy M et al.: High concentrations of histamine stimulate equine polymorphonuclear neutrophils to produce reactive oxygen species. Inflamm Res, 1999, 48, 594-601.
6. Bilici D, Akpinar E, Gursan N, Dengiz GO, Bilici S, Altas S: Protective effect of T-type calcium channel blocker in histamine-induced paw inflammation in rat. Pharmacol Res, 2001, 44, 527-531.
7. Blazso G, Razga Z, Gabor M: Effect of cinnarizine on different experimentally induced oedemas. Fundam Clin Pharmacol, 1999, 13, 91-95.
8. Briukhanov VM, Zverev IF, Elkin VI: The effect of calcium antagonists on the development of inflammatory effect in rat (in Russian). Exp Clin Pharmacol, 1994, 57, 47-49.
9. Carnevale KA, Cathcart MK: Calcium-independent phospholipase A2 is required for human monocyte chemotaxis to monocyte chemoattractant protein 1. J Immunol, 2001, 167, 3414-3421.
10. Cotran RS, Kumar V, Collins T. Inflammation and repair. In: Robbins Pathologic Basis of Disease. Ed. Cotran RS, Kumar V, Collins T, WB Saunders Company, Philadelphia, 1999, 50-89.
11. Crespi F: Dihydropyridines, nitric oxide and vascular protection. Curr Vasc Pharmacol, 2005, 3, 195-205.
12. Cuzzocrea S, Zingarelli B, Hake P, Salzman AL, Szabo C: Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. Free Radic Biol Med, 1998, 24, 450-459.
13. Da Motta JI, Cunha FQ, Vargaftig BB, Ferreira SH: Drug modulation of antigen-induced paw oedema in guinea-pig: effects of lipopolysaccaride, tumor necrosis factor and leucocyte depletion. Br J Pharmacol, 1994, 112, 111-116.
14. Elferinik JGR, Bonen GJJ, Koster BM: The role of calcium in neutrophil migration: the effect of calcium and calcium-antagonists in electroporated neutrophils. Biochem Biophys Res Commun, 1992, 182, 864-869.
15. Fansa L, Gol MK, Nisanoglu V, Yavas S, Iscan ZH, Tasdemir O: Does diltiazem inhibit the inflammatory response in cardiopulmonary bypass? Med Sci Monit, 2003, 9, 48-54.
16. Guiraudou P, Pucheu SC, Gayraud R, Gautier P, Roccon A, Herbert JM: Involvement of nitric oxide in amiodarone- and dronedarone-induced coronary vasodilation in guinea pig heart. Eur J Pharmacol, 2004, 496, 119-127.
17. Gurdal H, Sara Y, Tulunay FC: Effect of calcium channel blockers on formalin-induced nociception and inflammation in rats. Pharmacology, 1992, 44, 290-296.
18. Halici Z, Ozbakis-Dengiz G, Odabasoglu F, Suleyman H, Cadirci E, Halici M: Amiodarone has anti-inflammatory and anti-oxidative properties: An experimental study in rats with carrageenan-induced paw edema. Eur J Pharmacol, 2007, 566, 215-221.
19. Heath MF, Costa-Jussa FR, Jacobs JM, Jacobson W: The induction of pulmonary phospholipidosis and the inhibition of lysosomal phospholipases by amiodarone. Br J Exp Pathol, 1985, 66, 391-397.
20. Heusch G: Myocardial stunning: a role of calcium antagonists during ischemia. Cardiovasc Res, 1992, 26, 14-19.
21. Higgins AJ: The biology, pathophysiology and control of eicosanoids in inflammation. J Vet Pharmacol Ther, 1985, 8, 1-18.
22. Hostetler KY, Giordano JR, Jellison EJ: In vitro inhibition of lysosomal phospholipase A1 of rat lung by amiodarone and desethylamiodarone. Biochim Biophys Acta, 1988, 959, 316-321.
23. Ide T, Tsuisui H, Kinugawa S, Utsumi H, Takeshita A: Amoidarone protects cardiac myocytes against oxidative injury by its free radical scavenging action. Circulation, 1999, 100, 690-692.
24. Iwamato I, Ueki IF, Borson DM Nadel JA: Neutral endopepdidase modulates tachykinin-induced increase in vascular permeability in guinea-pig skin. Int Arch Allergy Appl Immunol, 1989, 88, 288-293.
25. Kodamo I, Kamiya K, Toyama J: Amiodarone: ionic and cellular mechanism of action of the most promising class III agent. Am J Cardiol, 1999, 84, 20R-28R.
26. Kodavanti UP, Mehendale HM: Cationic amphiphilic drugs and phospholipid storage disorders. Pharmacol Rev, 1990, 42, 327-354.
27. Lapenna D, Ciofani G, Bruno C, Pierdomenico SD, Cuccurullo F: Antioxidant activity of amiodarone on human lipoprotein oxidation. Br J Pharmacol, 2001, 133, 739-745.
28. Leslie CC: Properties and regulation of cytosolic phospholipase A2. J Biol Chem, 1997, 272, 16709-16712.
29. Lubic SP, Nguyen KP, Dave B, Giacomini JC: Antiarrhythmic agent amiodarone possesses calcium channel blocker properties. J Cardiovasc Pharmacol, 1994, 24, 707-714.
30. Martin WJ, Kachel DL, Vilen T, Natarjan W: Mechanism of phospholipidosis in amiodarone pulmonary toxicity. J Pharmacol Exp Ther, 1989, 251, 272-278.
31. McCord JM: Free radicals and inflammation: protection of synovial fluid by superoxide dismutase. Science, 1974, 185, 529-531.
32. McCord JM, Roy RS: The pathophysiology of superoxide. Role in inflammation and ischemia. Can J Physiol Pharmacol, 1982, 60, 1346-1352.
33. Oliveira PF, Dias da Silva VJ, Salgado MCO, Fazan Jr R, Aguiar CA, Salgado HC: Acute effect of amiodarone on cardiovascular reflexes of normotensive and renal hypertensive rats. Braz J Med Biol Res, 2005, 38, 967-976.
34. Raussel JP, Grazzini E, Guipponi M, Astier H: Dihydropyridine-like effects of amiodarone and desethylamiodarone on thyrotropin secretion and intracellular calcium concentration in rat pituitary. Eur J Endocrinol, 1995, 133, 489-498.
35. Roden DM, Antiarrhythmic drugs. In: Goodman and Gilman's the Pharmacological Basis of Therapeutics. Ed. Brunton LL, Mc Graw-Hill, New York, 2006, 899-932.
36. Rodrigues AJ, Evora PRB, Maruo A, Schaff HV. Amiodarone causes endothelium-dependent vasodilation in canine coronary arteries. Arq Bras Cardiol, 2005, 84, 251-255.
37. Rose S, Illerhaus M, Wiercinski A, Mutschler W, Marzi I: Altered calcium regulation and function of human neutrophils during multiple trauma. Shock, 2000, 13, 92-99.
38. Rousseau G, Provost P, Tran D, Caille G, Latour JG: Clentiazem given at reperfusion improves subendocardial reflow and reduces myocardial infarct size in the dog. J Pharmacol Exp Ther, 1994, 268, 1252-1260.
39. Salvemini D, Wang ZO, Bourdon DM, Stern MK, Currie MG, Manning PT: Evidence of peroxynitrite involvement in the carrageenan-induced rat paw oedema. Eur J Pharmacol, 1996, 303, 217-220.
40. Sanchez S, Bartrons R, Rodriguez L, Gonzalez P, Planas ME: Protective effect of nifedipine against carrageenan-induced inflammation. Pharmacology, 1998, 56, 131-136.
41. Sethi S, Singh MP, Dikshit M: Mechanism involved in the augmentation of arachidonic acid-induced free radical generation from rat neutrophils following hypoxia-reoxygenation. Thromb Res, 2000, 98, 445-450.
42. Suleyman H, Halici Z, Hacimuftuoglu A, Gocer F: Role of adrenal gland hormones in antiinflammatory effect of calcium channel blockers. Pharmacol Rep, 2006, 58, 692-699.
43. Wilson BD, Clarkson CE, Lippmann ML: Amiodarone causes decreased cell-mediated immune responses and inhibits the phospholipase C signalling pathway. Lung, 1993, 171, 137-148.
44. 2+ channel through distinct mechanisms. Mol Pharmacol (Fast Forward Article), 2006, doi, 10.1124/ mol.105.021253.