Expression of histamine receptors and effect of histamine in the rat carotid body chemoafferent pathway

European Journal of Neuroscience

Volumn 24, Issue 12, 2006, Pages 3431-3444

  Lazarov, Nikolai ^a,c   Rozloznik, Miroslav ^b   Reindl, Sebastian ^a   Rey Ares, Verónica ^a   Dutschmann, Mathias ^b   Gratzl, Manfred ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c TRAKIA UNIVERSITY   (Bulgaria)

Author keywords

Carotid body; Histamine; Histamine receptors; Nucleus of the solitary tract; Petrosal ganglion; Respiration

Indexed keywords

HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H3 RECEPTOR; HISTAMINE RECEPTOR; HISTIDINE DECARBOXYLASE;

ANIMAL TISSUE; ARTICLE; CAROTID BODY; CHEMORECEPTOR; CHEMOSENSITIVITY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; IMMUNOCYTOCHEMISTRY; MALE; NERVE CONDUCTION; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHRENIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESPIRATORY SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE; SIGNAL TRANSDUCTION;

AFFERENT PATHWAYS; AMIDINES; ANIMALS; BLOTTING, NORTHERN; CAROTID BODY; CHEMORECEPTORS; FEMALE; GENE EXPRESSION; HISTAMINE; HISTAMINE ANTAGONISTS; HISTIDINE DECARBOXYLASE; IMMUNOHISTOCHEMISTRY; MALE; MEDULLA OBLONGATA; MICROSCOPY, IMMUNOELECTRON; PHRENIC NERVE; PIPERIDINES; PYRILAMINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, HISTAMINE; RESPIRATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM CYANIDE;

EID: 33845622520     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.05241.x     Document Type: Article

References (37)

1. Arrang, J.M., Garbarg, M. & Schwartz, J.C. (1983) Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor. Nature, 302, 832-837.
2. Arrang, J.M., Garbarg, M. & Schwartz, J.C. (1985) Autoregulation of histamine release in brain by presynaptic H3-receptors. Neuroscience, 15, 553-562.
3. Boscan, P. & Paton, J.F. (2002) Nociceptive afferents selectively modulate the cardiac component of the peripheral chemoreceptor reflex via actions within the solitary tract nucleus. Neuroscience, 110, 319-328.
4. Boscan, P., Pickering, A.E. & Paton, J.F. (2002) The nucleus of the solitary tract: an integrating station for nociceptive and cardiorespiratory afferents. Exp. Physiol., 87, 259-266.
5. Coge, F., Guenin, S.P., Audinot, V., Renouard-Try, A., Beauverger, P., Macia, C., Ouvry, C., Nagel, N., Rique, H., Boutin, J.A. & Galizzi, J.P. (2001) Genomic organization and characterization of splice variants of the human histamine H3 receptor. Biochem. J., 355, 279-288.
6. Donnelly, D.F. (2000) Developmental aspects of oxygen sensing by the carotid body. J. Appl. Physiol., 88, 2296-2301.
7. Drutel, G., Peitsaro, N., Karlstedt, K., Wieland, K., Smit, M.J., Timmerman, H., Panula, P. & Leurs, R. (2001) Identification of rat H3 receptor isoforms with different brain expression and signaling properties. Mol. Pharmacol., 59, 1-8.
8. Dutschmann, M., Bischoff, A.M., Busselberg, D. & Richter, D.W. (2003) Histaminergic modulation of the intact respiratory network of adult mice. Pflugers Arch., 445, 570-576.
9. Feldman, J.L., Mitchell, G.S. & Nattie, E.E. (2003) Breathing: rhythmicity, plasticity, chemosensitivity. Annu. Rev. Neurosci., 26, 239-266.
10. Gauda, E.B. (2002) Gene expression in peripheral arterial chemoreceptors. Microsc. Res. Tech., 59, 153-167.
11. Heron, A., Rouleau, A., Cochois, V., Pillot, C., Schwartz, J.C. & Arrang, J.M. (2001) Expression analysis of the histamine H (3) receptor in developing rat tissues. Mech. Dev., 105, 167-173.
12. Hough, L.B. (2001) Genomics meets histamine receptors: new subtypes, new receptors. Mol. Pharmacol., 59, 415-419.
13. Huey, K.A., Szewczak, J.M. & Powell, F.L. (2003) Dopaminergic mechanisms of neural plasticity in respiratory control: transgenic approaches. Respir. Physiol. Neurobiol., 135, 133-144.
14. Hui, A.S., Striet, J.B., Gudelsky, G., Soukhova, G.K., Gozal, E., Beitner-Johnson, D., Guo, S.Z., Sachleben, L.R. Jr, Haycock, J.W., Gozal, D. & Czyzyk-Krzeska, M.F. (2003) Regulation of catecholamines by sustained and intermittent hypoxia in neuroendocrine cells and sympathetic neurons. Hypertension, 42, 1130-1136.
15. Ichikawa, H. (2002) Innervation of the carotid body: Immunohistochemical, denervation, and retrograde tracing studies. Microsc. Res. Tech., 59, 188-195.
16. Iturriaga, R. & Alcayaga, J. (2004) Neurotransmission in the carotid body: transmitters and modulators between glomus cells and petrosal ganglion nerve terminals. Brain Res. Brain Res. Rev., 47, 46-53.
17. Jacono, F.J., Peng, Y.J., Kumar, G.K. & Prabhakar, N.R. (2005) Modulation of the hypoxic sensory response of the carotid body by 5-hydroxytryptamine: role of the 5-HT2 receptor. Respir. Physiol. Neurobiol., 145, 135-142.
18. Koerner, P., Hesslinger, C., Schaefermeyer, A., Prinz, C. & Gratzl, M. (2004) Evidence for histamine as a transmitter in rat carotid body sensor cells. J. Neurochem., 91, 493-500.
19. Lazarov, N.E. & Gratzl, M. (2006) Selective expression of histamine receptors in rat mesencephalic trigeminal neurons. Neurosci. Lett., 404, 67-71.
20. Lopez-Barneo, J., Pardal, R. & Ortega-Saenz, P. (2001) Cellular mechanism of oxygen sensing. Annu. Rev. Physiol., 63, 259-287.
21. Lovenberg, T.W., Roland, B.L., Wilson, S.J., Jiang, X., Pyati, J., Huvar, A., Jackson, M.R. & Erlander, M.G. (1999) Cloning and functional expression of the human histamine H3 receptor. Mol. Pharmacol., 55, 1101-1107.
22. Miyamoto, K., Iwase, M., Kimura, H. & Homma, I. (2004) Central histamine contributes to the inspiratory off-switch mechanism via H1 receptors in mice. Respir. Physiol. Neurobiol., 144, 25-33.
23. Neubauer, J.A. & Sunderram, J. (2004) Oxygen-sensing neurons in the central nervous system. J. Appl. Physiol., 96, 367-374.
24. Nurse, C.A. (2005) Neurotransmission and neuromodulation in the chemosensory carotid body. Auton. Neurosci., 120, 1-9.
25. Paton, J.F. (1996) The ventral medullary respiratory network of the mature mouse studied in a working heart-brainstem preparation. J. Physiol. (Lond.), 493, 819-831.
26. Paxinos, G. & Watson, C. (1998) The Rat Brain in Stereotaxic Coordinates. Academic Press, Syndey.
27. Pillot, C., Heron, A., Cochois, V., Tardivel-Lacombe, J., Ligneau, X., Schwartz, J.C. & Arrang, J.M. (2002) A detailed mapping of the histamine H (3) receptor and its gene transcripts in rat brain. Neuroscience, 114, 173-193.
28. Richerson, G.B. (2004) Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat. Rev. Neurosci., 5, 449-461.
29. Richter, D.W., Manzke, T., Wilken, B. & Ponimaskin, E. (2003) Serotonin receptors: guardians of stable breathing. Trends Mol. Med., 9, 542-548.
30. Rouleau, A., Heron, A., Cochois, V., Pillot, C., Schwartz, J.C. & Arrang, J.M. (2004) Cloning and expression of the mouse histamine H3 receptor: evidence for multiple isoforms. J. Neurochem., 90, 1331-1338.
31. Sapru, H.N. (1996) Carotid chemoreflex. Neural pathways and transmitters. Adv. Exp. Med. Biol., 410, 357-364.
32. Schwartz, J.C., Arrang, J.M., Garbarg, M., Pollard, H. & Ruat, M. (1991) Histaminergic transmission in the mammalian brain. Physiol. Rev., 71, 1-51.
33. Song, G. & Poon, C.S. (2004) Functional and structural models of pontine modulation of mechanoreceptor and chemoreceptor reflexes. Respir. Physiol. Neurobiol., 143, 281-292.
34. Tankersley, C.G. (2003) Genetic aspects of breathing: on interactions between hypercapnia and hypoxia. Respir. Physiol. Neurobiol., 135, 167-178.
35. Wang, Z.Y., Keith, I.M., Beckman, M.J., Brownfield, M.S., Vidruk, E.H. & Bisgard, G.E. (2000) 5-HT5a receptors in the carotid body chemoreception pathway of rat. Neurosci. Lett., 278, 9-12.
36. Zhang, M., Fearon, I.M., Zhong, H. & Nurse, C.A. (2003) Presynaptic modulation of rat arterial chemoreceptor function by 5-HT: role of K+ channel inhibition via protein kinase C. J. Physiol. (Lond.), 551, 825-842.
37. Zhang, M. & Nurse, C.A. (2000) Does endogenous 5-HT mediate spontaneous rhythmic activity in chemoreceptor clusters of rat carotid body? Brain Res., 872, 199-203.