-
1
-
-
84899740340
-
DNA sequencing of cancer: what have we learned?
-
24274178
-
Chmielecki J, Meyerson M. DNA sequencing of cancer: what have we learned?. Annu Rev Med 2014, 65:63-79. 10.1146/annurev-med-060712-200152, 24274178.
-
(2014)
Annu Rev Med
, vol.65
, pp. 63-79
-
-
Chmielecki, J.1
Meyerson, M.2
-
2
-
-
84880472975
-
Precision oncology: an overview
-
23589545
-
Garraway LA, Verweij J, Ballman KV. Precision oncology: an overview. J Clin Oncol 2013, 31:1803-1805. 10.1200/JCO.2013.49.4799, 23589545.
-
(2013)
J Clin Oncol
, vol.31
, pp. 1803-1805
-
-
Garraway, L.A.1
Verweij, J.2
Ballman, K.V.3
-
3
-
-
84894107205
-
Human epidermal growth factor receptor family-targeted therapies in the treatment of HER2-overexpressing breast cancer
-
24436312
-
Eroglu Z, Tagawa T, Somlo G. Human epidermal growth factor receptor family-targeted therapies in the treatment of HER2-overexpressing breast cancer. Oncologist 2014, 19:135-150. 10.1634/theoncologist.2013-0283, 24436312.
-
(2014)
Oncologist
, vol.19
, pp. 135-150
-
-
Eroglu, Z.1
Tagawa, T.2
Somlo, G.3
-
4
-
-
84888305374
-
ALK inhibitors in the treatment of advanced NSCLC
-
23931927
-
Gridelli C, Peters S, Sgambato A, Casaluce F, Adjei AA, Ciardiello F. ALK inhibitors in the treatment of advanced NSCLC. Cancer Treat Rev 2014, 40:300-306. 10.1016/j.ctrv.2013.07.002, 23931927.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 300-306
-
-
Gridelli, C.1
Peters, S.2
Sgambato, A.3
Casaluce, F.4
Adjei, A.A.5
Ciardiello, F.6
-
5
-
-
84885927197
-
The frontline treatment of chronic myeloid leukemia in the chronic phase: current clinical decisions and future prospects for treatment
-
24083594
-
Jain N, O'Brien S. The frontline treatment of chronic myeloid leukemia in the chronic phase: current clinical decisions and future prospects for treatment. Expert Rev Hematol 2013, 6:575-586. 10.1586/17474086.2013.835697, 24083594.
-
(2013)
Expert Rev Hematol
, vol.6
, pp. 575-586
-
-
Jain, N.1
O'Brien, S.2
-
6
-
-
84877291745
-
Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis
-
23594426
-
Lee CK, Brown C, Gralla RJ, Hirsh V, Thongprasert S, Tsai CM, Tan EH, Ho JC, da Chu T, Zaatar A, Osorio Sanchez JA, Vu VV, Au JS, Inoue A, Lee SM, Gebski V, Yang JC. Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis. J Natl Cancer Inst 2013, 105:595-605. 10.1093/jnci/djt072, 23594426.
-
(2013)
J Natl Cancer Inst
, vol.105
, pp. 595-605
-
-
Lee, C.K.1
Brown, C.2
Gralla, R.J.3
Hirsh, V.4
Thongprasert, S.5
Tsai, C.M.6
Tan, E.H.7
Ho, J.C.8
da Chu, T.9
Zaatar, A.10
Osorio Sanchez, J.A.11
Vu, V.V.12
Au, J.S.13
Inoue, A.14
Lee, S.M.15
Gebski, V.16
Yang, J.C.17
-
7
-
-
84868224906
-
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
-
23020132
-
Flaherty KT, Infante JR, Daud A, Gonzalez R, Kefford RF, Sosman J, Hamid O, Schuchter L, Cebon J, Ibrahim N, Kudchadkar R, Burris HA, Falchook G, Algazi A, Lewis K, Long GV, Puzanov I, Lebowitz P, Singh A, Little S, Sun P, Allred A, Ouellet D, Kim KB, Patel K, Weber J. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 2012, 367:1694-1703. 10.1056/NEJMoa1210093, 23020132.
-
(2012)
N Engl J Med
, vol.367
, pp. 1694-1703
-
-
Flaherty, K.T.1
Infante, J.R.2
Daud, A.3
Gonzalez, R.4
Kefford, R.F.5
Sosman, J.6
Hamid, O.7
Schuchter, L.8
Cebon, J.9
Ibrahim, N.10
Kudchadkar, R.11
Burris, H.A.12
Falchook, G.13
Algazi, A.14
Lewis, K.15
Long, G.V.16
Puzanov, I.17
Lebowitz, P.18
Singh, A.19
Little, S.20
Sun, P.21
Allred, A.22
Ouellet, D.23
Kim, K.B.24
Patel, K.25
Weber, J.26
more..
-
8
-
-
84863230465
-
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
-
22281684
-
Prahallad A, Sun C, Huang S, Di Nicolantonio F, Salazar R, Zecchin D, Beijersbergen RL, Bardelli A, Bernards R. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature 2012, 483:100-103. 10.1038/nature10868, 22281684.
-
(2012)
Nature
, vol.483
, pp. 100-103
-
-
Prahallad, A.1
Sun, C.2
Huang, S.3
Di Nicolantonio, F.4
Salazar, R.5
Zecchin, D.6
Beijersbergen, R.L.7
Bardelli, A.8
Bernards, R.9
-
9
-
-
84904750123
-
Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment
-
24733792
-
Kurian AW, Hare EE, Mills MA, Kingham KE, McPherson L, Whittemore AS, McGuire V, Ladabaum U, Kobayashi Y, Lincoln SE, Cargill M, Ford JM. Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment. J Clin Oncol 2014, 32:2001-2009. 10.1200/JCO.2013.53.6607, 24733792.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2001-2009
-
-
Kurian, A.W.1
Hare, E.E.2
Mills, M.A.3
Kingham, K.E.4
McPherson, L.5
Whittemore, A.S.6
McGuire, V.7
Ladabaum, U.8
Kobayashi, Y.9
Lincoln, S.E.10
Cargill, M.11
Ford, J.M.12
-
10
-
-
84896730857
-
Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)
-
24508104
-
Andre F, Bachelot T, Commo F, Campone M, Arnedos M, Dieras V, Lacroix-Triki M, Lacroix L, Cohen P, Gentien D, Ade´laide J, Dalenc F, Goncalves A, Levy C, Ferrero JM, Bonneterre J, Lefeuvre C, Jimenez M, Filleron T, Bonnefoi H. Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER). Lancet Oncol 2014, 15:267-274. 10.1016/S1470-2045(13)70611-9, 24508104.
-
(2014)
Lancet Oncol
, vol.15
, pp. 267-274
-
-
Andre, F.1
Bachelot, T.2
Commo, F.3
Campone, M.4
Arnedos, M.5
Dieras, V.6
Lacroix-Triki, M.7
Lacroix, L.8
Cohen, P.9
Gentien, D.10
Ade´laide, J.11
Dalenc, F.12
Goncalves, A.13
Levy, C.14
Ferrero, J.M.15
Bonneterre, J.16
Lefeuvre, C.17
Jimenez, M.18
Filleron, T.19
Bonnefoi, H.20
more..
-
11
-
-
84887127701
-
A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias
-
24180494
-
Cortes JE, Kim DW, Pinilla-Ibarz J, le Coutre P, Paquette R, Chuah C, Nicolini FE, Apperley JF, Khoury HJ, Talpaz M, DiPersio J, DeAngelo DJ, Abruzzese E, Rea D, Baccarani M, Mu¨ller MC, Gambacorti-Passerini C, Wong S, Lustgarten S, Rivera VM, Clackson T, Turner CD, Haluska FG, Guilhot F, Deininger MW, Hochhaus A, Hughes T, Goldman JM, Shah NP, Kantarjian H, et al. A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias. N Engl J Med 2013, 369:1783-1796. 10.1056/NEJMoa1306494, 24180494.
-
(2013)
N Engl J Med
, vol.369
, pp. 1783-1796
-
-
Cortes, J.E.1
Kim, D.W.2
Pinilla-Ibarz, J.3
le Coutre, P.4
Paquette, R.5
Chuah, C.6
Nicolini, F.E.7
Apperley, J.F.8
Khoury, H.J.9
Talpaz, M.10
DiPersio, J.11
DeAngelo, D.J.12
Abruzzese, E.13
Rea, D.14
Baccarani, M.15
Mu¨ller, M.C.16
Gambacorti-Passerini, C.17
Wong, S.18
Lustgarten, S.19
Rivera, V.M.20
Clackson, T.21
Turner, C.D.22
Haluska, F.G.23
Guilhot, F.24
Deininger, M.W.25
Hochhaus, A.26
Hughes, T.27
Goldman, J.M.28
Shah, N.P.29
Kantarjian, H.30
more..
-
12
-
-
84873902360
-
Noncovalent wild-type-sparing inhibitors of EGFR T790M
-
23229345
-
Lee HJ, Schaefer G, Heffron TP, Shao L, Ye X, Sideris S, Malek S, Chan E, Merchant M, La H, Ubhayakar S, Yauch RL, Pirazzoli V, Politi K, Settleman J. Noncovalent wild-type-sparing inhibitors of EGFR T790M. Cancer Discov 2013, 3:168-181. 10.1158/2159-8290.CD-12-0357, 23229345.
-
(2013)
Cancer Discov
, vol.3
, pp. 168-181
-
-
Lee, H.J.1
Schaefer, G.2
Heffron, T.P.3
Shao, L.4
Ye, X.5
Sideris, S.6
Malek, S.7
Chan, E.8
Merchant, M.9
La, H.10
Ubhayakar, S.11
Yauch, R.L.12
Pirazzoli, V.13
Politi, K.14
Settleman, J.15
-
13
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
23945592
-
Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Borresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjo¨rd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M, Ja¨ger N, Jones DT, Jones D, Knappskog S, Kool M, et al. Signatures of mutational processes in human cancer. Nature 2013, 500:415-421. 10.1038/nature12477, 23945592.
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
Biankin, A.V.6
Bignell, G.R.7
Bolli, N.8
Borg, A.9
Borresen-Dale, A.L.10
Boyault, S.11
Burkhardt, B.12
Butler, A.P.13
Caldas, C.14
Davies, H.R.15
Desmedt, C.16
Eils, R.17
Eyfjo¨rd, J.E.18
Foekens, J.A.19
Greaves, M.20
Hosoda, F.21
Hutter, B.22
Ilicic, T.23
Imbeaud, S.24
Imielinski, M.25
Ja¨ger, N.26
Jones, D.T.27
Jones, D.28
Knappskog, S.29
Kool, M.30
more..
-
14
-
-
84884997982
-
Emerging landscape of oncogenic signatures across human cancers
-
24071851
-
Ciriello G, Miller ML, Aksoy BA, Senbabaoglu Y, Schultz N, Sander C. Emerging landscape of oncogenic signatures across human cancers. Nat Genet 2013, 45:1127-1133. 10.1038/ng.2762, 24071851.
-
(2013)
Nat Genet
, vol.45
, pp. 1127-1133
-
-
Ciriello, G.1
Miller, M.L.2
Aksoy, B.A.3
Senbabaoglu, Y.4
Schultz, N.5
Sander, C.6
-
15
-
-
84890471418
-
My Cancer Genome
-
My Cancer Genome. www.mycancergenome.org
-
-
-
-
16
-
-
84905850596
-
National Cancer Institute's Precision Medicine Initiatives for the new National Clinical Trials Network
-
Abrams J, Conley B, Mooney M, Zwiebel J, Chen A, Welch JJ, Takebe N, Malik S, McShane L, Korn E, Williams M, Staudt L, Doroshow J. National Cancer Institute's Precision Medicine Initiatives for the new National Clinical Trials Network. Am Soc Clin Oncol Educ 2014, :71-76.
-
(2014)
Am Soc Clin Oncol Educ
, pp. 71-76
-
-
Abrams, J.1
Conley, B.2
Mooney, M.3
Zwiebel, J.4
Chen, A.5
Welch, J.J.6
Takebe, N.7
Malik, S.8
McShane, L.9
Korn, E.10
Williams, M.11
Staudt, L.12
Doroshow, J.13
-
17
-
-
84877814639
-
Treating breast cancer in the 21st century: emerging biological therapies
-
23386910
-
Tinoco G, Warsch S, Gluck S, Avancha K, Montero AJ. Treating breast cancer in the 21st century: emerging biological therapies. J Cancer 2013, 4:117-132. 10.7150/jca.4925, 23386910.
-
(2013)
J Cancer
, vol.4
, pp. 117-132
-
-
Tinoco, G.1
Warsch, S.2
Gluck, S.3
Avancha, K.4
Montero, A.J.5
-
18
-
-
77955862852
-
A randomized phase II trial comparing exemestane, letrozole, and anastrozole in postmenopausal women with clinical stage II/III estrogen receptor-positive breast cancer
-
abstract LBA513
-
Ellis MJ, Buzdar A, Unzeitig GW, Esserman L, Leitch AM, Dershryver K, Allred DC, Suman V, Hunt K, Olson JA. A randomized phase II trial comparing exemestane, letrozole, and anastrozole in postmenopausal women with clinical stage II/III estrogen receptor-positive breast cancer. J Clin Oncol 2010, 28(18, suppl):abstract LBA513.
-
(2010)
J Clin Oncol
, vol.28
, Issue.18
-
-
Ellis, M.J.1
Buzdar, A.2
Unzeitig, G.W.3
Esserman, L.4
Leitch, A.M.5
Dershryver, K.6
Allred, D.C.7
Suman, V.8
Hunt, K.9
Olson, J.A.10
-
19
-
-
84905824179
-
A multicenter phase II study of cisplatin or carboplatin for metastatic triple negative breast cancer and evaluation of p63/p73 as a biomarker of response
-
abstract 1025
-
Isakoff SJ, Goss PE, Mayer EL, Traina TA, Carey LA, Krag K, Rugo HS, Liu MC, Stearns V, Come SE, Borger DR, Quadrino CA, Finkelstein D, Garber JE, Ryan PD, Winer EP, Ellisen LW. A multicenter phase II study of cisplatin or carboplatin for metastatic triple negative breast cancer and evaluation of p63/p73 as a biomarker of response. J Clin Oncol 2011, 29(15, suppl):abstract 1025.
-
(2011)
J Clin Oncol
, vol.29
, Issue.15
-
-
Isakoff, S.J.1
Goss, P.E.2
Mayer, E.L.3
Traina, T.A.4
Carey, L.A.5
Krag, K.6
Rugo, H.S.7
Liu, M.C.8
Stearns, V.9
Come, S.E.10
Borger, D.R.11
Quadrino, C.A.12
Finkelstein, D.13
Garber, J.E.14
Ryan, P.D.15
Winer, E.P.16
Ellisen, L.W.17
-
20
-
-
84896071725
-
PI3KCA mutations and correlation with pCR in the NeoALTTO trial (BIG 01-06)
-
abstract 1859
-
Baselga J, Majewski I, Nuciforo PG. PI3KCA mutations and correlation with pCR in the NeoALTTO trial (BIG 01-06). Eur Cancer Congress 2013, :abstract 1859.
-
(2013)
Eur Cancer Congress
-
-
Baselga, J.1
Majewski, I.2
Nuciforo, P.G.3
-
21
-
-
84905850597
-
Extraordinary responders to lapatinib with trastuzumab in primary-refractory IBC share a common cancer genotype
-
O'Shaughnessy J. Extraordinary responders to lapatinib with trastuzumab in primary-refractory IBC share a common cancer genotype. San Antonio Breast Cancer Symposium 2013, :.
-
(2013)
San Antonio Breast Cancer Symposium
-
-
O'Shaughnessy, J.1
-
22
-
-
84862523863
-
Sequence analysis of mutations and translocations across breast cancer subtypes
-
22722202
-
Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Cortes ML, Fernandez-Lopez JC, Peng S, Ardlie KG, Auclair D, Bautista-Piña V, Duke F, Francis J, Jung J, Maffuz-Aziz A, Onofrio RC, Parkin M, Pho NH, Quintanar-Jurado V, Ramos AH, Rebollar-Vega R, Rodriguez-Cuevas S, Romero-Cordoba SL, Schumacher SE, Stransky N, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature 2012, 486:405-409. 10.1038/nature11154, 22722202.
-
(2012)
Nature
, vol.486
, pp. 405-409
-
-
Banerji, S.1
Cibulskis, K.2
Rangel-Escareno, C.3
Brown, K.K.4
Carter, S.L.5
Frederick, A.M.6
Lawrence, M.S.7
Sivachenko, A.Y.8
Sougnez, C.9
Zou, L.10
Cortes, M.L.11
Fernandez-Lopez, J.C.12
Peng, S.13
Ardlie, K.G.14
Auclair, D.15
Bautista-Piña, V.16
Duke, F.17
Francis, J.18
Jung, J.19
Maffuz-Aziz, A.20
Onofrio, R.C.21
Parkin, M.22
Pho, N.H.23
Quintanar-Jurado, V.24
Ramos, A.H.25
Rebollar-Vega, R.26
Rodriguez-Cuevas, S.27
Romero-Cordoba, S.L.28
Schumacher, S.E.29
Stransky, N.30
more..
-
23
-
-
84862584058
-
Whole-genome analysis informs breast cancer response to aromatase inhibition
-
22722193
-
Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, Weber J, Chen K, Koboldt DC, Kandoth C, Schierding WS, McMichael JF, Miller CA, Lu C, Harris CC, McLellan MD, Wendl MC, DeSchryver K, Allred DC, Esserman L, Unzeitig G, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature 2012, 486:353-360. 22722193.
-
(2012)
Nature
, vol.486
, pp. 353-360
-
-
Ellis, M.J.1
Ding, L.2
Shen, D.3
Luo, J.4
Suman, V.J.5
Wallis, J.W.6
Van Tine, B.A.7
Hoog, J.8
Goiffon, R.J.9
Goldstein, T.C.10
Ng, S.11
Lin, L.12
Crowder, R.13
Snider, J.14
Ballman, K.15
Weber, J.16
Chen, K.17
Koboldt, D.C.18
Kandoth, C.19
Schierding, W.S.20
McMichael, J.F.21
Miller, C.A.22
Lu, C.23
Harris, C.C.24
McLellan, M.D.25
Wendl, M.C.26
DeSchryver, K.27
Allred, D.C.28
Esserman, L.29
Unzeitig, G.30
more..
-
24
-
-
84862526929
-
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
-
22495314
-
Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, Turashvili G, Ding J, Tse K, Haffari G, Bashashati A, Prentice LM, Khattra J, Burleigh A, Yap D, Bernard V, McPherson A, Shumansky K, Crisan A, Giuliany R, Heravi-Moussavi A, Rosner J, Lai D, Birol I, Varhol R, Tam A, Dhalla N, Zeng T, Ma K, Chan SK, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 2012, 486:395-399. 22495314.
-
(2012)
Nature
, vol.486
, pp. 395-399
-
-
Shah, S.P.1
Roth, A.2
Goya, R.3
Oloumi, A.4
Ha, G.5
Zhao, Y.6
Turashvili, G.7
Ding, J.8
Tse, K.9
Haffari, G.10
Bashashati, A.11
Prentice, L.M.12
Khattra, J.13
Burleigh, A.14
Yap, D.15
Bernard, V.16
McPherson, A.17
Shumansky, K.18
Crisan, A.19
Giuliany, R.20
Heravi-Moussavi, A.21
Rosner, J.22
Lai, D.23
Birol, I.24
Varhol, R.25
Tam, A.26
Dhalla, N.27
Zeng, T.28
Ma, K.29
Chan, S.K.30
more..
-
25
-
-
84861576201
-
The landscape of cancer genes and mutational processes in breast cancer
-
22722201
-
Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, Yates LR, Papaemmanuil E, Beare D, Butler A, Cheverton A, Gamble J, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, Lau KW, McLaren S, McBride DJ, Menzies A, Mudie L, Raine K, Rad R, Chapman MS, Teague J, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature 2012, 486:400-404. 22722201.
-
(2012)
Nature
, vol.486
, pp. 400-404
-
-
Stephens, P.J.1
Tarpey, P.S.2
Davies, H.3
Van Loo, P.4
Greenman, C.5
Wedge, D.C.6
Nik-Zainal, S.7
Martin, S.8
Varela, I.9
Bignell, G.R.10
Yates, L.R.11
Papaemmanuil, E.12
Beare, D.13
Butler, A.14
Cheverton, A.15
Gamble, J.16
Hinton, J.17
Jia, M.18
Jayakumar, A.19
Jones, D.20
Latimer, C.21
Lau, K.W.22
McLaren, S.23
McBride, D.J.24
Menzies, A.25
Mudie, L.26
Raine, K.27
Rad, R.28
Chapman, M.S.29
Teague, J.30
more..
-
26
-
-
84923649644
-
Exome sequencing reveals clinically actionable mutations in the pathogenesis and metastasis of triple negative breast cancer
-
Abstract S4-03, San Antonio, TX
-
Blackwell K, Hamilton EP, Marcom PK. Exome sequencing reveals clinically actionable mutations in the pathogenesis and metastasis of triple negative breast cancer. Paper presented at: 36th Annual San Antonio Breast Cancer Symposium; December 10-14 2013, Abstract S4-03., San Antonio, TX.
-
(2013)
Paper presented at: 36th Annual San Antonio Breast Cancer Symposium; December 10-14
-
-
Blackwell, K.1
Hamilton, E.P.2
Marcom, P.K.3
-
27
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
11287973
-
Druker BJ, Sawyers CL, Kantarjian H, Resta DJ, Reese SF, Ford JM, Capdeville R, Talpaz M. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001, 344:1038-1042. 10.1056/NEJM200104053441402, 11287973.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Reese, S.F.5
Ford, J.M.6
Capdeville, R.7
Talpaz, M.8
-
28
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
21639808
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, O'Day SJ, Sosman JA, Kirkwood JM, Eggermont AM, Dreno B, Nolop K, Li J, Nelson B, Hou J, Lee RJ, Flaherty KT, McArthur GA. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011, 364:2507-2516. 10.1056/NEJMoa1103782, 21639808.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
Dummer, R.7
Garbe, C.8
Testori, A.9
Maio, M.10
Hogg, D.11
Lorigan, P.12
Lebbe, C.13
Jouary, T.14
Schadendorf, D.15
Ribas, A.16
O'Day, S.J.17
Sosman, J.A.18
Kirkwood, J.M.19
Eggermont, A.M.20
Dreno, B.21
Nolop, K.22
Li, J.23
Nelson, B.24
Hou, J.25
Lee, R.J.26
Flaherty, K.T.27
McArthur, G.A.28
more..
-
29
-
-
84863541347
-
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people
-
22604722
-
Nelson MR, Wegmann D, Ehm MG, Kessner D, St Jean P, Verzilli C, Shen J, Tang Z, Bacanu SA, Fraser D, Warren L, Aponte J, Zawistowski M, Liu X, Zhang H, Zhang Y, Li J, Li Y, Li L, Woollard P, Topp S, Hall MD, Nangle K, Wang J, Abecasis G, Cardon LR, Zo¨llner S, Whittaker JC, Chissoe SL, Novembre J, Mooser V. An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science 2012, 337:100-104. 10.1126/science.1217876, 22604722.
-
(2012)
Science
, vol.337
, pp. 100-104
-
-
Nelson, M.R.1
Wegmann, D.2
Ehm, M.G.3
Kessner, D.4
St Jean, P.5
Verzilli, C.6
Shen, J.7
Tang, Z.8
Bacanu, S.A.9
Fraser, D.10
Warren, L.11
Aponte, J.12
Zawistowski, M.13
Liu, X.14
Zhang, H.15
Zhang, Y.16
Li, J.17
Li, Y.18
Li, L.19
Woollard, P.20
Topp, S.21
Hall, M.D.22
Nangle, K.23
Wang, J.24
Abecasis, G.25
Cardon, L.R.26
Zo¨llner, S.27
Whittaker, J.C.28
Chissoe, S.L.29
Novembre, J.30
Mooser, V.31
more..
-
30
-
-
84863556835
-
Evolution and functional impact of rare coding variation from deep sequencing of human exomes
-
22604720
-
Tennessen JA, Bigham AW, O'Connor TD, Fu W, Kenny EE, Gravel S, McGee S, Do R, Liu X, Jun G, Kang HM, Jordan D, Leal SM, Gabriel S, Rieder MJ, Abecasis G, Altshuler D, Nickerson DA, Boerwinkle E, Sunyaev S, Bustamante CD, Bamshad MJ, Akey JM, Broad GO, Seattle GO. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science 2012, 337:64-69. 10.1126/science.1219240, 22604720.
-
(2012)
Science
, vol.337
, pp. 64-69
-
-
Tennessen, J.A.1
Bigham, A.W.2
O'Connor, T.D.3
Fu, W.4
Kenny, E.E.5
Gravel, S.6
McGee, S.7
Do, R.8
Liu, X.9
Jun, G.10
Kang, H.M.11
Jordan, D.12
Leal, S.M.13
Gabriel, S.14
Rieder, M.J.15
Abecasis, G.16
Altshuler, D.17
Nickerson, D.A.18
Boerwinkle, E.19
Sunyaev, S.20
Bustamante, C.D.21
Bamshad, M.J.22
Akey, J.M.23
Broad, G.O.24
Seattle, G.O.25
more..
-
31
-
-
84899476119
-
Guidelines for investigating causality of sequence variants in human disease
-
24759409
-
MacArthur DG, Manolio TA, Dimmock DP, Rehm HL, Shendure J, Abecasis GR, Adams DR, Altman RB, Antonarakis SE, Ashley EA, Barrett JC, Biesecker LG, Conrad DF, Cooper GM, Cox NJ, Daly MJ, Gerstein MB, Goldstein DB, Hirschhorn JN, Leal SM, Pennacchio LA, Stamatoyannopoulos JA, Sunyaev SR, Valle D, Voight BF, Winckler W, Gunter C. Guidelines for investigating causality of sequence variants in human disease. Nature 2014, 508:469-476. 10.1038/nature13127, 24759409.
-
(2014)
Nature
, vol.508
, pp. 469-476
-
-
MacArthur, D.G.1
Manolio, T.A.2
Dimmock, D.P.3
Rehm, H.L.4
Shendure, J.5
Abecasis, G.R.6
Adams, D.R.7
Altman, R.B.8
Antonarakis, S.E.9
Ashley, E.A.10
Barrett, J.C.11
Biesecker, L.G.12
Conrad, D.F.13
Cooper, G.M.14
Cox, N.J.15
Daly, M.J.16
Gerstein, M.B.17
Goldstein, D.B.18
Hirschhorn, J.N.19
Leal, S.M.20
Pennacchio, L.A.21
Stamatoyannopoulos, J.A.22
Sunyaev, S.R.23
Valle, D.24
Voight, B.F.25
Winckler, W.26
Gunter, C.27
more..
-
32
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
22397650
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, Martinez P, Matthews N, Stewart A, Tarpey P, Varela I, Phillimore B, Begum S, McDonald NQ, Butler A, Jones D, Raine K, Latimer C, Santos CR, Nohadani M, Eklund AC, Spencer-Dene B, Clark G, Pickering L, Stamp G, Gore M, Szallasi Z, Downward J, Futreal PA, Swanton C. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012, 366:883-892. 10.1056/NEJMoa1113205, 22397650.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
Martinez, P.7
Matthews, N.8
Stewart, A.9
Tarpey, P.10
Varela, I.11
Phillimore, B.12
Begum, S.13
McDonald, N.Q.14
Butler, A.15
Jones, D.16
Raine, K.17
Latimer, C.18
Santos, C.R.19
Nohadani, M.20
Eklund, A.C.21
Spencer-Dene, B.22
Clark, G.23
Pickering, L.24
Stamp, G.25
Gore, M.26
Szallasi, Z.27
Downward, J.28
Futreal, P.A.29
Swanton, C.30
more..
-
33
-
-
78650373172
-
Drug discovery: How melanomas bypass new therapy
-
21164474
-
Solit D, Sawyers CL. Drug discovery: How melanomas bypass new therapy. Nature 2010, 468:902-903. 10.1038/468902a, 21164474.
-
(2010)
Nature
, vol.468
, pp. 902-903
-
-
Solit, D.1
Sawyers, C.L.2
-
34
-
-
84905828740
-
Lung Cancer Master Protocol Activation Announcement
-
Accessed 27 May 2014
-
Lung Cancer Master Protocol Activation Announcement. Accessed 27 May 2014., http://www.focr.org/sites/default/files/Lung%20Cancer%20Master%20Protocol%20Activation%20Announcement%20Slides.pdf
-
-
-
|