Protective effect of rutin on LPS-induced acute lung injury via down-regulation of MIP-2 expression and MMP-9 activation through inhibition of Akt phosphorylation

International Immunopharmacology

Volumn 22, Issue 2, 2014, Pages 409-413

  Chen, Wen Ying ^a   Huang, Yi Chun ^b   Yang, Ming Ling ^c   Lee, Chien Ying ^c,d   Chen, Chun Jung ^e   Yeh, Chung Hsin ^f,g   Pan, Pin Ho ^h   Horng, Chi Ting ⁱ   Kuo, Wu Hsien ^i,j   Kuan, Yu Hsiang ^c,d  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL TAICHUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^f SHOW CHWAN MEMORIAL HOSPITAL   (Taiwan)

^g HUNGKUANG UNIVERSITY   (Taiwan)

^h TUNGS' TAICHUNG METROHARBOR HOSPITAL   (Taiwan)

ⁱ Kaohsiung Armed Force General Hospital   (Taiwan)

^j TRI SERVICE GENERAL HOSPITAL   (Taiwan)

more..

Author keywords

Acute lung injury; Akt; LPS; MIP 2; MMP 9; Rutin

Indexed keywords

CXCL2 CHEMOKINE; CXCL2 PROTEIN, MOUSE; GELATINASE B; LIPOPOLYSACCHARIDE; MMP9 PROTEIN, MOUSE; PROTECTIVE AGENT; PROTEIN KINASE B; RUTOSIDE;

ACUTE LUNG INJURY; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; DOWN REGULATION; DRUG EFFECTS; IMMUNOLOGY; LUNG; LUNG LAVAGE; METABOLISM; MOUSE; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHOSPHORYLATION;

ACUTE LUNG INJURY; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINE CXCL2; DOWN-REGULATION; LIPOPOLYSACCHARIDES; LUNG; MATRIX METALLOPROTEINASE 9; MICE; NEUTROPHIL INFILTRATION; PHOSPHORYLATION; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; RUTIN;

EID: 84905819020     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.07.026     Document Type: Article

References (33)

1. R. Iscimen, R. Cartin-Ceba, M. Yilmaz, H. Khan, R.D. Hubmayr, and B. Afessa Risk factors for the development of acute lung injury in patients with septic shock: an observational cohort study Crit Care Med 36 2008 1518 1522 (Pubitemid 351620653)
2. M. Rojas, C.R. Woods, A.L. Mora, J. Xu, and K.L. Brigham Endotoxin-induced lung injury in mice: structural, functional, and biochemical responses Am J Physiol Lung Cell Mol Physiol 288 2005 L333 L341
3. B.M. Varisco The pharmacology of acute lung injury in sepsis Adv Pharmacol Sci 2011 2011 254619
4. J. Grommes, and O. Soehnlein Contribution of neutrophils to acute lung injury Mol Med 17 2011 293 307
5. M.Y. Kuo, M.F. Liao, F.L. Chen, Y.C. Li, M.L. Yang, and R.H. Lin et al. Luteolin attenuates the pulmonary inflammatory response in mice with endotoxin-induced acute lung injury which involves antioxidation and inhibition of MAPK and NFκB pathways Food Chem Toxicol 49 2011 2660 2666
6. Y.C. Li, C.H. Yeh, M.L. Yang, and Y.H. Kuan Luteolin suppresses inflammatory mediator expression by blocking the Akt/NFκB pathway in acute lung injury induced by lipopolysaccharide in mice Evid Based Complement Alternat Med 2012 2012 383608
7. L.P. Kane, V.S. Shapiro, D. Stokoe, and A. Weiss Induction of NF-kB by the Akt/PKB kinase Curr Biol 9 1999 601 604
8. S.I. Said, and K.G. Dickman Pathways of inflammation and cell death in the lung: modulation by vasoactive intestinal peptide Regul Pept 93 2000 21 29
9. R. Guo, and P. Wei Studies on the antioxidant effect of rutin in the microenvironment of cationic micelles Microchim Acta 161 2008 233 239
10. S. Lee, S. Suh, and S. Kim Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils Neurosci Lett 287 2000 191 194 (Pubitemid 30339381)
11. A. Novakovic, L. Gojkovic-Bukarica, M. Peric, D. Nezic, B. Djukanovic, and J. Markovic-Lipkovski et al. The mechanism of endothelium-independent relaxation induced by the wine polyphenol resveratrol in human internal mammary artery J Pharmacol Sci 101 2006 85 90 (Pubitemid 43765339)
12. A. Korkmaz, and D. Kolankaya Protective effect of rutin on the ischemia/reperfusion induced damage in rat kidney J Surg Res 164 2010 309 315
13. C.H. Yeh, J.J. Yang, M.L. Yang, Y.C. Li, and Y.H. Kuan Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-κB pathway Free Radic Biol Med 69C 2014 249 257
14. C.H. Huang, M.L. Yang, C.H. Tsai, Y.C. Li, Y.J. Lin, and Y.H. Kuan Ginkgo biloba leaves extract (EGB 761) attenuates lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and NF-kB-dependent matrix metalloproteinase-9 pathway Phytomedicine 20 2013 303 309
15. C.H. Yeh, M.L. Yang, C.Y. Lee, M.L. Yang, C.J. Chen, and Y.H. Kuan Wogonin attenuates endotoxin-induced prostaglandin E2 and nitric oxide production via Src-ERK1/2-NFκB pathway in BV-2 microglial cells Environ Toxicol 2013 10.1002/tox.21847
16. M. Bhatia, and S. Moochhala Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome J Pathol 202 2004 145 156 (Pubitemid 38208651)
17. J. Reutershan, M.A. Morris, T.L. Burcin, D.F. Smith, D. Chang, and M.S. Saprito et al. Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung J Clin Invest 116 2006 695 702 (Pubitemid 43326878)
18. L.F. Li, C.C. Huang, H.C. Lin, Y.H. Tsai, D.A. Quinn, and S.K. Liao Unfractionated heparin and enoxaparin reduce high stretch ventilation-augmented lung injury - a prospective, controlled animal experiment Crit Care 13 2009 R108
19. C. Moon, J.R. Han, H.J. Park, J.S. Hah, and J.L. Kang Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways Respir Res 10 2009 18
20. Z. He, Y. Zhu, and H. Jiang Inhibiting toll-like receptor 4 signaling ameliorates pulmonary fibrosis during acute lung injury induced by lipopolysaccharide: an experimental study Respir Res 10 2009 126
21. H. Chen, C. Bai, and X. Wang The value of the lipopolysaccharide-induced acute lung injury model in respiratory medicine Expert Rev Respir Med 4 2010 773 783
22. A.G. Proudfoot, D.F. McAuley, M.J. Griffiths, and M. Hind Human models of acute lung injury Dis Model Mech 4 2011 145 153
23. L.E. Rovai, H.R. Herschman, and J.B. Smith The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2 have distinct induction kinetics, tissue distributions, and tissue-specific sensitivities to glucocorticoid regulation in endotoxemia J Leukoc Biol 64 1998 494 502 (Pubitemid 28455395)
24. M. Singer, and P.J. Sansonetti IL-8 is a key chemokine regulating neutrophil recruitment in a new mouse model of Shigella-induced colitis J Immunol 173 2004 4197 4206 (Pubitemid 39280786)
25. T. Nojiri, H. Hosoda, T. Tokudome, K. Miura, S. Ishikane, and T. Kimura et al. Atrial natriuretic peptide inhibits lipopolysaccharide-induced acute lung injury Pulm Pharmacol Ther 2014 10.1016/j.pupt.2014.01.003
26. S. Chakrabarti, and K.D. Patel Matrix metalloproteinase-2 (MMP-2) and MMP-9 in pulmonary pathology Exp Lung Res 31 2005 599 621 (Pubitemid 40967244)
27. J.L. Kang, H.W. Lee, H.S. Lee, I.S. Pack, Y. Chong, and V. Castranova et al. Genistein prevents nuclear factor-kappa B activation and acute lung injury induced by lipopolysaccharide Am J Respir Crit Care Med 164 2001 2206 2212 (Pubitemid 34032937)
28. J.W. Jang, J.K. Lee, H. Hur, T.W. Kim, S.P. Joo, and M.S. Piao Rutin improves functional outcome via reducing the elevated matrix metalloproteinase-9 level in a photothrombotic focal ischemic model of rats J Neurol Sci 339 2014 75 80
29. W.N. Lin, S.F. Luo, C.B. Wu, C.C. Lin, and C.M. Yang Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: involvement of Src/EGFR/PI3-K/Akt pathway Toxicol Appl Pharmacol 228 2008 256 268
30. W. Lee, S.K. Ku, and J.S. Bae Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo Food Chem Toxicol 50 2012 3048 3055
31. K.Y. Su, C.Y. Yu, Y.P. Chen, K.F. Hua, and Y.L. Chen 3,4- Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling BMC Complement Altern Med 14 2014 21
32. X. Ci, X. Chu, M. Wei, X. Yang, Q. Cai, and X. Deng Different effects of farrerol on an OVA-induced allergic asthma and LPS-induced acute lung injury PLoS ONE 7 2012 e34634
33. O. Araz, E. Demirci, E. Yilmazel Ucar, M. Calik, D. Pulur, and A. Karaman et al. Comparison of reducing effect on lung injury of dexamethasone and bosentan in acute lung injury: an experimental study Multidiscip Respir Med 8 2013 74