-
1
-
-
0019408557
-
Asymmetric total synthesis of erythromcin. 1. Synthesis of an erythronolide a seco acid derivativeviaasymmetric induction
-
Woodward RB, Logusch E, Nambiar KP, et al. Asymmetric total synthesis of erythromcin. 1. Synthesis of an erythronolide a seco acid derivativeviaasymmetric induction. J Am Chem Soc 1981; 103: 3210-3213.
-
(1981)
J Am Chem Soc
, vol.103
, pp. 3210-3213
-
-
Woodward, R.B.1
Logusch, E.2
Nambiar, K.P.3
-
3
-
-
0038135144
-
Macrolide antibiotics: Binding site, mechanism of action, resistance
-
Gaynor M, Mankin AS. Macrolide antibiotics: binding site, mechanism of action, resistance. Curr Top Med Chem 2003; 3: 949-961.
-
(2003)
Curr Top Med Chem
, vol.3
, pp. 949-961
-
-
Gaynor, M.1
Mankin, A.S.2
-
4
-
-
0036716799
-
Resistance to macrolides and related antibiotics inStreptococcus pneumoniae
-
Leclercq R, Courvalin P. Resistance to macrolides and related antibiotics inStreptococcus pneumoniae. Antimicrob Agents Chemother 2002; 46: 2727-2734.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 2727-2734
-
-
Leclercq, R.1
Courvalin, P.2
-
5
-
-
4143124486
-
Macrolides and ketolides: Azithromycin, clarithromycin, telithromycin
-
Zuckerman JM. Macrolides and ketolides: azithromycin, clarithromycin, telithromycin. Infect Dis Clin North Am 2004; 18: 621-649.
-
(2004)
Infect Dis Clin North Am
, vol.18
, pp. 621-649
-
-
Zuckerman, J.M.1
-
6
-
-
0032789314
-
Etiology of community-acquired pneumonia: Impact of age, comorbidity, and severity
-
Ruiz M, Ewig S, Marcos MA, et al. Etiology of community-acquired pneumonia: impact of age, comorbidity, and severity. Am J Respir Crit Care Med 1999; 160: 397-405.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 397-405
-
-
Ruiz, M.1
Ewig, S.2
Marcos, M.A.3
-
7
-
-
0033542045
-
Processes and outcomes of care for patients with community-acquired pneumonia: Results from the Pneumonia Patient Outcomes Research Team (PORT) cohort study
-
Fine MJ, Stone RA, Singer DE, et al. Processes and outcomes of care for patients with community-acquired pneumonia: results from the Pneumonia Patient Outcomes Research Team (PORT) cohort study. Arch Intern Med 1999; 159: 970-980.
-
(1999)
Arch Intern Med
, vol.159
, pp. 970-980
-
-
Fine, M.J.1
Stone, R.A.2
Singer, D.E.3
-
8
-
-
33847155159
-
Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
-
Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007; 44: Suppl. 2, S27-S72.
-
(2007)
Clin Infect Dis
, vol.44
, Issue.SUPPL. 2
-
-
Mandell, L.A.1
Wunderink, R.G.2
Anzueto, A.3
-
9
-
-
77349095417
-
BTS guidelines for the management of community acquired pneumonia in adults: Update 2009
-
Lim WS, Baudouin SV, George RC, et al. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax 2009; 64: Suppl. 3, iii1-iii55.
-
(2009)
Thorax
, vol.64
, Issue.SUPPL. 3
-
-
Lim, W.S.1
Baudouin, S.V.2
George, R.C.3
-
10
-
-
0033596067
-
Effect of macrolides as part of initial empiric therapy on length of stay in patients hospitalized with community-acquired pneumonia
-
Stahl JE, Barza M, DesJardin J, et al. Effect of macrolides as part of initial empiric therapy on length of stay in patients hospitalized with community-acquired pneumonia. Arch Intern Med 1999; 159: 2576-2580.
-
(1999)
Arch Intern Med
, vol.159
, pp. 2576-2580
-
-
Stahl, J.E.1
Barza, M.2
DesJardin, J.3
-
11
-
-
0037442372
-
Addition of a macrolide to ab-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia
-
Martinez JA, Horcajada JP, Almela M, et al. Addition of a macrolide to ab-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia. Clin Infect Dis 2003; 36: 389-395.
-
(2003)
Clin Infect Dis
, vol.36
, pp. 389-395
-
-
Martinez, J.A.1
Horcajada, J.P.2
Almela, M.3
-
12
-
-
0037541094
-
Impact of initial antibiotic choice on clinical outcomes in communityacquired pneumonia: Analysis of a hospital claims-made database
-
Brown RB, Iannini P, Gross P, et al. Impact of initial antibiotic choice on clinical outcomes in communityacquired pneumonia: analysis of a hospital claims-made database. Chest 2003; 123: 1503-1511.
-
(2003)
Chest
, vol.123
, pp. 1503-1511
-
-
Brown, R.B.1
Iannini, P.2
Gross, P.3
-
13
-
-
84893313755
-
Macrolides and mortality in critically ill patients with community-acquired pneumonia: A systematic review and meta-analysis
-
[In press DOI: 10. 1097/CCM. 0b013e3182a66b9b]
-
Sligl WI, Asadi L, Eurich DT, et al. Macrolides and mortality in critically ill patients with community-acquired pneumonia: a systematic review and meta-analysis. Crit Care Med2013 [In press DOI: 10. 1097/CCM. 0b013e3182a66b9b].
-
(2013)
Crit Care Med
-
-
Sligl, W.I.1
Asadi, L.2
Eurich, D.T.3
-
14
-
-
58849166805
-
Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia
-
Restrepo MI, Mortensen EM, Waterer GW, et al. Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia. Eur Respir J2009; 33: 153-159.
-
(2009)
Eur Respir J
, vol.33
, pp. 153-159
-
-
Restrepo, M.I.1
Mortensen, E.M.2
Waterer, G.W.3
-
15
-
-
77951209165
-
Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia
-
Martin-Loeches I, Lisboa T, Rodriguez A, et al. Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia. Intensive Care Med 2010; 36: 612-620.
-
(2010)
Intensive Care Med
, vol.36
, pp. 612-620
-
-
Martin-Loeches, I.1
Lisboa, T.2
Rodriguez, A.3
-
16
-
-
34249304464
-
Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock
-
Rodríguez A, Mendia A, Sirvent JM, et al. Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock. Crit Care Med 2007; 35: 1493-1498.
-
(2007)
Crit Care Med
, vol.35
, pp. 1493-1498
-
-
Rodríguez, A.1
Mendia, A.2
Sirvent, J.M.3
-
17
-
-
35848941214
-
Comparison of b-lactam and macrolide combination therapyversus fluoroquinolone monotherapy in hospitalized Veterans Affairs patients with community-acquired pneumonia
-
Lodise TP, Kwa A, Cosler L, et al. Comparison of b-lactam and macrolide combination therapyversus fluoroquinolone monotherapy in hospitalized Veterans Affairs patients with community-acquired pneumonia. Antimicrob Agents Chemother 2007; 51: 3977-3982.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3977-3982
-
-
Lodise, T.P.1
Kwa, A.2
Cosler, L.3
-
18
-
-
42549119145
-
Effect of clarithromycin in patients with sepsis and ventilator-associated pneumonia
-
Giamarellos-Bourboulis EJ, Pechère JC, Routsi C, et al. Effect of clarithromycin in patients with sepsis and ventilator-associated pneumonia. Clin Infect Dis 2008; 46: 1157-1164.
-
(2008)
Clin Infect Dis
, vol.46
, pp. 1157-1164
-
-
Giamarellos-Bourboulis, E.J.1
Pechère, J.C.2
Routsi, C.3
-
19
-
-
84863933351
-
Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: A systematic review and meta-analysis
-
Asadi L, Sligl WI, Eurich DT, et al. Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: a systematic review and meta-analysis. Clin Infect Dis 2012; 55: 371-380.
-
(2012)
Clin Infect Dis
, vol.55
, pp. 371-380
-
-
Asadi, L.1
Sligl, W.I.2
Eurich, D.T.3
-
20
-
-
84873036547
-
Empiric antibiotic coverage of atypical pathogens for communityacquired pneumonia in hospitalized adults
-
pub4
-
Eliakim-Raz N, Robenshtok E, Shefet D, et al. Empiric antibiotic coverage of atypical pathogens for communityacquired pneumonia in hospitalized adults. Cochrane Database Syst Rev 2012; 9: CD004418. pub4.
-
(2012)
Cochrane Database Syst Rev
, vol.9
-
-
Eliakim-Raz, N.1
Robenshtok, E.2
Shefet, D.3
-
21
-
-
13244291394
-
Anti-inflammatory effects of macrolides-an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions?
-
Amsden GW. Anti-inflammatory effects of macrolides-an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions?J Antimicrob Chemother 2005; 55: 10-21.
-
(2005)
J Antimicrob Chemother
, vol.55
, pp. 10-21
-
-
Amsden, G.W.1
-
22
-
-
0032015311
-
Erythromycin treatment in diffuse panbronchiolitis
-
Kudoh S. Erythromycin treatment in diffuse panbronchiolitis. Curr Opin Pulm Med 1998; 4: 116-121.
-
(1998)
Curr Opin Pulm Med
, vol.4
, pp. 116-121
-
-
Kudoh, S.1
-
23
-
-
0031807730
-
Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin
-
Kudoh S, Azuma A, Yamamoto M, et al. Improvement of survival in patients with diffuse panbronchiolitis treated with low-dose erythromycin. Am J Respir Crit Care Med 1998; 157: 1829-1832.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1829-1832
-
-
Kudoh, S.1
Azuma, A.2
Yamamoto, M.3
-
24
-
-
0025652191
-
[Long-term therapeutic effects of erythromycin and newquinolone antibacterial agents on diffuse panbronchiolitis]
-
Yamamoto M, Kondo A, Tamura M, et al. [Long-term therapeutic effects of erythromycin and newquinolone antibacterial agents on diffuse panbronchiolitis]. Nihon Kyobu Shikkan Gakkai Zasshi 1990; 28: 1305-1313.
-
(1990)
Nihon Kyobu Shikkan Gakkai Zasshi
, vol.28
, pp. 1305-1313
-
-
Yamamoto, M.1
Kondo, A.2
Tamura, M.3
-
25
-
-
0032748411
-
Erythromycin inhibits transcriptional activation of NF-kB, but not NFAT, through calcineurinindependent signaling in T cells
-
Aoki Y, Kao PN. Erythromycin inhibits transcriptional activation of NF-kB, but not NFAT, through calcineurinindependent signaling in T cells. Antimicrob Agents Chemother 1999; 43: 2678-2684.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 2678-2684
-
-
Aoki, Y.1
Kao, P.N.2
-
26
-
-
33847688940
-
Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells
-
Cigana C, Assael BM, Melotti P. Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells. Antimicrob Agents Chemother 2007; 51: 975-981.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 975-981
-
-
Cigana, C.1
Assael, B.M.2
Melotti, P.3
-
27
-
-
10644283833
-
Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection
-
Tsai WC, Rodriguez ML, Young KS, et al. Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection. Am J Respir Crit Care Med 2004; 170: 1331-1339.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1331-1339
-
-
Tsai, W.C.1
Rodriguez, M.L.2
Young, K.S.3
-
28
-
-
0030070464
-
Interleukin 1b, tumor necrosis factor a, and interleukin 8 in bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis: A potential mechanism of macrolide therapy
-
Sakito O, Kadota J, Kohno S, et al. Interleukin 1b, tumor necrosis factor a, and interleukin 8 in bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis: a potential mechanism of macrolide therapy. Respiration 1996; 63: 42-48.
-
(1996)
Respiration
, vol.63
, pp. 42-48
-
-
Sakito, O.1
Kadota, J.2
Kohno, S.3
-
29
-
-
0027930611
-
Role of interleukin-8 (IL-8) and an inhibitory effect of erythromycin on IL-8 release in the airways of patients with chronic airway diseases
-
Oishi K, Sonoda F, Kobayashi S, et al. Role of interleukin-8 (IL-8) and an inhibitory effect of erythromycin on IL-8 release in the airways of patients with chronic airway diseases. Infect Immun 1994; 62: 4145-4152.
-
(1994)
Infect Immun
, vol.62
, pp. 4145-4152
-
-
Oishi, K.1
Sonoda, F.2
Kobayashi, S.3
-
30
-
-
0032925065
-
Fourteen-member macrolides inhibit interleukin-8 release by human eosinophils from atopic donors
-
Kohyama T, Takizawa H, Kawasaki S, et al. Fourteen-member macrolides inhibit interleukin-8 release by human eosinophils from atopic donors. Antimicrob Agents Chemother 1999; 43: 907-911.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 907-911
-
-
Kohyama, T.1
Takizawa, H.2
Kawasaki, S.3
-
31
-
-
0037199689
-
Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects
-
Culić O, Eraković V, Cepelak I, et al. Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects. Eur J Pharmacol 2002; 450: 277-289.
-
(2002)
Eur J Pharmacol
, vol.450
, pp. 277-289
-
-
Culić, O.1
Eraković, V.2
Cepelak, I.3
-
32
-
-
0032792527
-
Clinical and immunoregulatory effects of roxithromycin therapy for chronic respiratory tract infection
-
Nakamura H, Fujishima S, Inoue T, et al. Clinical and immunoregulatory effects of roxithromycin therapy for chronic respiratory tract infection. Eur Respir J1999; 13: 1371-1379.
-
(1999)
Eur Respir J
, vol.13
, pp. 1371-1379
-
-
Nakamura, H.1
Fujishima, S.2
Inoue, T.3
-
33
-
-
0024536234
-
Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages
-
Savill JS, Wyllie AH, Henson JE, et al. Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest 1989; 83: 865-875.
-
(1989)
J Clin Invest
, vol.83
, pp. 865-875
-
-
Savill, J.S.1
Wyllie, A.H.2
Henson, J.E.3
-
34
-
-
2442567002
-
Suppression of matrix metalloproteinase production from nasal fibroblasts by macrolide antibioticsin vitro
-
Kanai K, Asano K, Hisamitsu T, et al. Suppression of matrix metalloproteinase production from nasal fibroblasts by macrolide antibioticsin vitro. Eur Respir J2004; 23: 671-678.
-
(2004)
Eur Respir J
, vol.23
, pp. 671-678
-
-
Kanai, K.1
Asano, K.2
Hisamitsu, T.3
-
35
-
-
0033808917
-
The effects of erythromycin on human peripheral neutrophil apoptosis
-
Inamura K, Ohta N, Fukase S, et al. The effects of erythromycin on human peripheral neutrophil apoptosis. Rhinology 2000; 38: 124-129.
-
(2000)
Rhinology
, vol.38
, pp. 124-129
-
-
Inamura, K.1
Ohta, N.2
Fukase, S.3
-
36
-
-
0028903792
-
Erythromycin shortens neutrophil survival by accelerating apoptosis
-
Aoshiba K, Nagai A, Konno K. Erythromycin shortens neutrophil survival by accelerating apoptosis. Antimicrob Agents Chemother 1995; 39: 872-877.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 872-877
-
-
Aoshiba, K.1
Nagai, A.2
Konno, K.3
-
37
-
-
77954595517
-
Mechanisms of action and clinical application of macrolides as immunomodulatory medications
-
Kanoh S, Rubin BK. Mechanisms of action and clinical application of macrolides as immunomodulatory medications. Clin Microbiol Rev 2010; 23: 590-615.
-
(2010)
Clin Microbiol Rev
, vol.23
, pp. 590-615
-
-
Kanoh, S.1
Rubin, B.K.2
-
38
-
-
0029114526
-
Effect of roxithromycin on peripheral neutrophil adhesion molecules in patients with chronic lower respiratory tract disease
-
Kusano S, Kadota J, Kohno S, et al. Effect of roxithromycin on peripheral neutrophil adhesion molecules in patients with chronic lower respiratory tract disease. Respiration 1995; 62: 217-222.
-
(1995)
Respiration
, vol.62
, pp. 217-222
-
-
Kusano, S.1
Kadota, J.2
Kohno, S.3
-
39
-
-
0030940526
-
Endothelin production and effects of endothelin antagonism during experimental airway inflammation
-
Finsnes F, Skjønsberg OH, Tønnessen T, et al. Endothelin production and effects of endothelin antagonism during experimental airway inflammation. Am J Respir Crit Care Med 1997; 155: 1404-1412.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 1404-1412
-
-
Finsnes, F.1
Skjønsberg, O.H.2
Tønnessen, T.3
-
40
-
-
0031867390
-
Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells
-
Takizawa H, Desaki M, Ohtoshi T, et al. Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells. Eur Respir J1998; 12: 57-63.
-
(1998)
Eur Respir J
, vol.12
, pp. 57-63
-
-
Takizawa, H.1
Desaki, M.2
Ohtoshi, T.3
-
41
-
-
0026644179
-
Role of phospholipase D-derived diradylglycerol in the activation of the human neutrophil respiratory burst oxidase. Inhibition by phosphatidic acid phosphohydrolase inhibitors
-
Perry DK, Hand WL, Edmondson DE, et al. Role of phospholipase D-derived diradylglycerol in the activation of the human neutrophil respiratory burst oxidase. Inhibition by phosphatidic acid phosphohydrolase inhibitors. J Immunol 1992; 149: 2749-2758.
-
(1992)
J Immunol
, vol.149
, pp. 2749-2758
-
-
Perry, D.K.1
Hand, W.L.2
Edmondson, D.E.3
-
42
-
-
0025121957
-
Macrophages and polymorphonuclear neutrophils in lung defense and injury
-
Sibille Y, Reynolds HY. Macrophages and polymorphonuclear neutrophils in lung defense and injury. Am Rev Respir Dis 1990; 141: 471-501.
-
(1990)
Am Rev Respir Dis
, vol.141
, pp. 471-501
-
-
Sibille, Y.1
Reynolds, H.Y.2
-
43
-
-
43149102069
-
Effect of erythromycin on bronchial hyperreactivity and inflammation in ovalbumin-sensitized brown Norway rats
-
Lin CC, Liaw SF, Wu KM, et al. Effect of erythromycin on bronchial hyperreactivity and inflammation in ovalbumin-sensitized brown Norway rats. Respir Physiol Neurobiol 2008; 161: 267-272.
-
(2008)
Respir Physiol Neurobiol
, vol.161
, pp. 267-272
-
-
Lin, C.C.1
Liaw, S.F.2
Wu, K.M.3
-
44
-
-
0016244155
-
Clinical trial design in studies of corticosteroids for bacterial infections
-
Weitzman S, Berger S. Clinical trial design in studies of corticosteroids for bacterial infections. Ann Intern Med 1974; 81: 36-42.
-
(1974)
Ann Intern Med
, vol.81
, pp. 36-42
-
-
Weitzman, S.1
Berger, S.2
-
45
-
-
84862663670
-
Treatment with anti-inflammatory drugs in community-acquired pneumonia
-
Meijvis SC, van de Garde EM, Rijkers GT, et al. Treatment with anti-inflammatory drugs in community-acquired pneumonia. J Intern Med 2012; 272: 25-35.
-
(2012)
J Intern Med
, vol.272
, pp. 25-35
-
-
Meijvis, S.C.1
van de Garde, E.M.2
Rijkers, G.T.3
-
46
-
-
0036158859
-
Modulatory effect of macrolide antibiotics on the Th1-and Th2-type cytokine production
-
Morikawa K, Zhang J, Nonaka M, et al. Modulatory effect of macrolide antibiotics on the Th1-and Th2-type cytokine production. Int J Antimicrob Agents 2002; 19: 53-59.
-
(2002)
Int J Antimicrob Agents
, vol.19
, pp. 53-59
-
-
Morikawa, K.1
Zhang, J.2
Nonaka, M.3
-
47
-
-
0031728726
-
Antibiotic-induced release of lipoteichoic acid and peptidoglycan fromStaphylococcus aureus: Quantitative measurements and biological reactivities
-
Van Langevelde P, van Dissel JT, Ravensbergen E, et al. Antibiotic-induced release of lipoteichoic acid and peptidoglycan fromStaphylococcus aureus: quantitative measurements and biological reactivities. Antimicrob Agents Chemother 1998; 42: 3073-3078.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3073-3078
-
-
Van Langevelde, P.1
van Dissel, J.T.2
Ravensbergen, E.3
-
48
-
-
0033727626
-
Subinhibitory concentrations of erythromycin reduce pneumococcal adherence to respiratory epithelial cellsin vitro
-
Lagrou K, Peetermans WE, Jorissen M, et al. Subinhibitory concentrations of erythromycin reduce pneumococcal adherence to respiratory epithelial cellsin vitro. J Antimicrob Chemother 2000; 46: 717-723.
-
(2000)
J Antimicrob Chemother
, vol.46
, pp. 717-723
-
-
Lagrou, K.1
Peetermans, W.E.2
Jorissen, M.3
-
49
-
-
0036586082
-
Release of cytokines by human nasal epithelial cells and peripheral blood mononuclear cells infected withMycoplasma pneumoniae
-
Kazachkov MY, Hu PC, Carson JL, et al. Release of cytokines by human nasal epithelial cells and peripheral blood mononuclear cells infected withMycoplasma pneumoniae. Exp Biol Med (Maywood)2002; 227: 330-335.
-
(2002)
Exp Biol Med (Maywood)
, vol.227
, pp. 330-335
-
-
Kazachkov, M.Y.1
Hu, P.C.2
Carson, J.L.3
-
50
-
-
0033940225
-
Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: Effects ofStreptococcus pneumoniae
-
Koch CC, Esteban DJ, Chin AC, et al. Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: effects ofStreptococcus pneumoniae. J Antimicrob Chemother 2000; 46: 19-26.
-
(2000)
J Antimicrob Chemother
, vol.46
, pp. 19-26
-
-
Koch, C.C.1
Esteban, D.J.2
Chin, A.C.3
-
52
-
-
0036605506
-
Effect of macrolide antibiotics on human endothelial cells activated by Chlamydia pneumoniaeinfection and tumor necrosis factor-a
-
Uriarte SM, Molestina RE, Miller RD, et al. Effect of macrolide antibiotics on human endothelial cells activated by Chlamydia pneumoniaeinfection and tumor necrosis factor-a. J Infect Dis 2002; 185: 1631-1636.
-
(2002)
J Infect Dis
, vol.185
, pp. 1631-1636
-
-
Uriarte, S.M.1
Molestina, R.E.2
Miller, R.D.3
-
53
-
-
0029556783
-
The effect of conditioned medium from cultured human bronchial epithelial cells on eosinophil and neutrophil chemotaxis and adherencein vitro
-
Abdelaziz MM, Devalia JL, Khair OA, et al. The effect of conditioned medium from cultured human bronchial epithelial cells on eosinophil and neutrophil chemotaxis and adherencein vitro. Am J Respir Cell Mol Biol 1995; 13: 728-737.
-
(1995)
Am J Respir Cell Mol Biol
, vol.13
, pp. 728-737
-
-
Abdelaziz, M.M.1
Devalia, J.L.2
Khair, O.A.3
-
54
-
-
24144436945
-
Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimentalMycoplasma pneumoniaepneumonia
-
Rios AM, Fonseca-Aten M, Mejías A, et al. Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimentalMycoplasma pneumoniaepneumonia. Antimicrob Agents Chemother 2005; 49: 3970-3973.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 3970-3973
-
-
Rios, A.M.1
Fonseca-Aten, M.2
Mejías, A.3
-
55
-
-
3342991541
-
Impact of cethromycin (ABT-773) therapy on microbiological, histologic, immunologic, and respiratory indices in a murine model ofMycoplasma pneumoniaelower respiratory infection
-
Rios AM, Mejias A, Chavez-Bueno S, et al. Impact of cethromycin (ABT-773) therapy on microbiological, histologic, immunologic, and respiratory indices in a murine model ofMycoplasma pneumoniaelower respiratory infection. Antimicrob Agents Chemother 2004; 48: 2897-2904.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2897-2904
-
-
Rios, A.M.1
Mejias, A.2
Chavez-Bueno, S.3
-
56
-
-
0038673558
-
Antimicrobial and immunologic activities of clarithromycin in a murine model ofMycoplasma pneumoniae-induced pneumonia
-
Hardy RD, Rios AM, Chavez-Bueno S, et al. Antimicrobial and immunologic activities of clarithromycin in a murine model ofMycoplasma pneumoniae-induced pneumonia. Antimicrob Agents Chemother 2003; 47: 1614-1620.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 1614-1620
-
-
Hardy, R.D.1
Rios, A.M.2
Chavez-Bueno, S.3
-
57
-
-
0035165625
-
Kinetic study of the inflammatory response inStreptococcus pneumoniae experimental pneumonia treated with the ketolide HMR 3004
-
Duong M, Simard M, Bergeron Y, et al. Kinetic study of the inflammatory response inStreptococcus pneumoniae experimental pneumonia treated with the ketolide HMR 3004. Antimicrob Agents Chemother 2001; 45: 252-262.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 252-262
-
-
Duong, M.1
Simard, M.2
Bergeron, Y.3
-
58
-
-
54749144115
-
The impact of steroids given with macrolide therapy on experimentalMycoplasma pneumoniaerespiratory infection
-
Tagliabue C, Salvatore CM, Techasaensiri C, et al. The impact of steroids given with macrolide therapy on experimentalMycoplasma pneumoniaerespiratory infection. J Infect Dis 2008; 198: 1180-1188.
-
(2008)
J Infect Dis
, vol.198
, pp. 1180-1188
-
-
Tagliabue, C.1
Salvatore, C.M.2
Techasaensiri, C.3
-
59
-
-
75749098848
-
Efficacy of clarithromycin against experimentally induced pneumonia caused by clarithromycin-resistantHaemophilus influenzaein mice
-
Nakamura S, Yanagihara K, Araki N, et al. Efficacy of clarithromycin against experimentally induced pneumonia caused by clarithromycin-resistantHaemophilus influenzaein mice. Antimicrob Agents Chemother 2010; 54: 757-762.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 757-762
-
-
Nakamura, S.1
Yanagihara, K.2
Araki, N.3
-
60
-
-
34248368413
-
Roxithromycin favorably modifies the initial phase of resistance against infection with macrolide-resistant Streptococcus pneumoniaein a murine pneumonia model
-
Yasuda Y, Kasahara K, Mizuno F, et al. Roxithromycin favorably modifies the initial phase of resistance against infection with macrolide-resistant Streptococcus pneumoniaein a murine pneumonia model. Antimicrob Agents Chemother 2007; 51: 1741-1752.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 1741-1752
-
-
Yasuda, Y.1
Kasahara, K.2
Mizuno, F.3
-
61
-
-
1942454728
-
Effect of multiple doses of clarithromycin and amoxicillin on IL-6, IFNc and IL-10 plasma levels in patients with community acquired pneumonia
-
Demartini G, Esposti D, Marthyn P, et al. Effect of multiple doses of clarithromycin and amoxicillin on IL-6, IFNc and IL-10 plasma levels in patients with community acquired pneumonia. J Chemother 2004; 16: 82-85.
-
(2004)
J Chemother
, vol.16
, pp. 82-85
-
-
Demartini, G.1
Esposti, D.2
Marthyn, P.3
-
62
-
-
84862557241
-
Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis cause by Gram-negative bacteria: Results from a randomized clinical study
-
Spyridaki A, Raftogiannis M, Antonopoulou A, et al. Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis cause by Gram-negative bacteria: results from a randomized clinical study. Antimicrob Agents Chemother 2012; 56: 3819-3825.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 3819-3825
-
-
Spyridaki, A.1
Raftogiannis, M.2
Antonopoulou, A.3
-
63
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
Seok J, Warren HS, Cuenca AG, et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci USA2013; 110: 3507-3512.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 3507-3512
-
-
Seok, J.1
Warren, H.S.2
Cuenca, A.G.3
-
64
-
-
35448968988
-
Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin byStreptococcus pneumoniae in vitro
-
Anderson R, Steel HC, Cockeran R, et al. Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin byStreptococcus pneumoniae in vitro. J Antimicrob Chemother 2007; 60: 1155-1158.
-
(2007)
J Antimicrob Chemother
, vol.60
, pp. 1155-1158
-
-
Anderson, R.1
Steel, H.C.2
Cockeran, R.3
-
65
-
-
84863690101
-
Pathogen-and host-directed anti-inflammatory activities of macrolide antibiotics
-
Steel HC, Theron AJ, Cockeran R, et al. Pathogen-and host-directed anti-inflammatory activities of macrolide antibiotics. Mediators Inflamm 2012; 2012: 584262.
-
(2012)
Mediators Inflamm
, vol.2012
, pp. 584262
-
-
Steel, H.C.1
Theron, A.J.2
Cockeran, R.3
-
66
-
-
0033535713
-
Induction of type 2 Shiga toxin synthesis inEscherichia coliO157 by 4-quinolones
-
Kimmitt PT, Harwood CR, Barer MR. Induction of type 2 Shiga toxin synthesis inEscherichia coliO157 by 4-quinolones. Lancet 1999; 353: 1588-1589.
-
(1999)
Lancet
, vol.353
, pp. 1588-1589
-
-
Kimmitt, P.T.1
Harwood, C.R.2
Barer, M.R.3
-
67
-
-
0034729744
-
The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coliO157: H7 infections
-
Wong CS, Jelacic S, Habeeb RL, et al. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coliO157: H7 infections. N Engl J Med 2000; 342: 1930-1936.
-
(2000)
N Engl J Med
, vol.342
, pp. 1930-1936
-
-
Wong, C.S.1
Jelacic, S.2
Habeeb, R.L.3
-
68
-
-
33846161259
-
Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistantStaphylococcus aureus
-
Stevens DL, Ma Y, Salmi DB, et al. Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistantStaphylococcus aureus. J Infect Dis 2007; 195: 202-211.
-
(2007)
J Infect Dis
, vol.195
, pp. 202-211
-
-
Stevens, D.L.1
Ma, Y.2
Salmi, D.B.3
-
69
-
-
40549092348
-
Effect of antibiotics, alone and in combination, on Panton-Valentine leukocidin production by a Staphylococcus aureusreference strain
-
Dumitrescu O, Badiou C, Bes M, et al. Effect of antibiotics, alone and in combination, on Panton-Valentine leukocidin production by a Staphylococcus aureusreference strain. Clin Microbiol Infect 2008; 14: 384-388.
-
(2008)
Clin Microbiol Infect
, vol.14
, pp. 384-388
-
-
Dumitrescu, O.1
Badiou, C.2
Bes, M.3
-
70
-
-
36549081013
-
Pathogenesis and treatment of Shiga toxin-producingEscherichia coliinfections
-
Serna At., Boedeker EC. Pathogenesis and treatment of Shiga toxin-producingEscherichia coliinfections. Curr Opin Gastroenterol 2008; 24: 38-47.
-
(2008)
Curr Opin Gastroenterol
, vol.24
, pp. 38-47
-
-
Serna, A.1
Boedeker, E.C.2
-
71
-
-
77955786950
-
Different classes of antibiotics differentially influence shiga toxin production
-
McGannon CM, Fuller CA, Weiss AA. Different classes of antibiotics differentially influence shiga toxin production. Antimicrob Agents Chemother 2010; 54: 3790-3798.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3790-3798
-
-
McGannon, C.M.1
Fuller, C.A.2
Weiss, A.A.3
-
72
-
-
4444366938
-
Increased antibiotic resistance in respiratory tract pathogens: PROTEKT US-an update
-
Karchmer AW. Increased antibiotic resistance in respiratory tract pathogens: PROTEKT US-an update. Clin Infect Dis 2004; 39: Suppl. 3, S142-S150.
-
(2004)
Clin Infect Dis
, vol.39
, Issue.SUPPL. 3
-
-
Karchmer, A.W.1
-
73
-
-
0036194468
-
Ketolides in the treatment of respiratory infections
-
Zhanel GG, Hoban DJ. Ketolides in the treatment of respiratory infections. Expert Opin Pharmacother 2002; 3: 277-297.
-
(2002)
Expert Opin Pharmacother
, vol.3
, pp. 277-297
-
-
Zhanel, G.G.1
Hoban, D.J.2
-
74
-
-
0032950956
-
The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA
-
Hansen LH, Mauvais P, Douthwaite S. The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Mol Microbiol 1999; 31: 623-631.
-
(1999)
Mol Microbiol
, vol.31
, pp. 623-631
-
-
Hansen, L.H.1
Mauvais, P.2
Douthwaite, S.3
-
75
-
-
15644366975
-
Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): A new class of antibacterials highly potent against macrolide-resistant and-susceptible respiratory pathogens
-
Agouridas C, Denis A, Auger JM, et al. Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and-susceptible respiratory pathogens. J Med Chem 1988; 41: 4080-4100.
-
(1988)
J Med Chem
, vol.41
, pp. 4080-4100
-
-
Agouridas, C.1
Denis, A.2
Auger, J.M.3
-
76
-
-
0033962264
-
Macrolide resistance and erythromycin resistance determinants among BelgianStreptococcus pyogenesandStreptococcus pneumoniaeisolates
-
Descheemaeker P, Chapelle S, Lammens C, et al. Macrolide resistance and erythromycin resistance determinants among BelgianStreptococcus pyogenesandStreptococcus pneumoniaeisolates. J Antimicrob Chemother. 2000; 45: 167-173.
-
(2000)
J Antimicrob Chemother.
, vol.45
, pp. 167-173
-
-
Descheemaeker, P.1
Chapelle, S.2
Lammens, C.3
-
77
-
-
0032904341
-
A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre
-
Xiong L, Shah S, Mauvais P, et al. A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre. Mol Microbiol 1999; 31: 633-639.
-
(1999)
Mol Microbiol
, vol.31
, pp. 633-639
-
-
Xiong, L.1
Shah, S.2
Mauvais, P.3
-
78
-
-
0034090751
-
In vitroactivity of telithromycin (HMR3647), a new ketolide, against clinical isolates ofMycoplasma pneumoniaein Japan
-
Yamaguchi T, Hirakata Y, Izumikawa K, et al. In vitroactivity of telithromycin (HMR3647), a new ketolide, against clinical isolates ofMycoplasma pneumoniaein Japan. Antimicrob Agents Chemother 2000; 44: 1381-1382.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1381-1382
-
-
Yamaguchi, T.1
Hirakata, Y.2
Izumikawa, K.3
-
79
-
-
84905733714
-
-
Date last accessed: October 2013. Date last updated:, US Food and Drug Federation
-
US Food and Drug Federation. Ketek (telithromyin). www. fda. gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm152681. htm Date last accessed: October 2013. Date last updated: 2007.
-
(2007)
Ketek (telithromyin)
-
-
-
80
-
-
81555231418
-
Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line
-
Otsu K, Ishinaga H, Suzuki S, et al. Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. Pharmacology 2011; 88: 327-332.
-
(2011)
Pharmacology
, vol.88
, pp. 327-332
-
-
Otsu, K.1
Ishinaga, H.2
Suzuki, S.3
-
81
-
-
0027436439
-
Adverse effects of macrolide antibacterials
-
Periti P, Mazzei T, Mini E, et al. Adverse effects of macrolide antibacterials. Drug Saf 1993; 9: 346-364.
-
(1993)
Drug Saf
, vol.9
, pp. 346-364
-
-
Periti, P.1
Mazzei, T.2
Mini, E.3
-
82
-
-
10944272743
-
Antibacterial resistance worldwide: Causes, challenges and responses
-
Levy SB, Marshall B. Antibacterial resistance worldwide: causes, challenges and responses. Nat Med 2004; 10: S122-S129.
-
(2004)
Nat Med
, vol.10
-
-
Levy, S.B.1
Marshall, B.2
-
83
-
-
33846817134
-
Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: A randomised, double-blind, placebo-controlled study
-
Malhotra-Kumar S, Lammens C, Coenen S, et al. Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study. Lancet 2007; 369: 482-490.
-
(2007)
Lancet
, vol.369
, pp. 482-490
-
-
Malhotra-Kumar, S.1
Lammens, C.2
Coenen, S.3
-
84
-
-
0036732832
-
Molecular characterization of macrolide resistance mechanisms among Streptococcus pneumoniaeandStreptococcus pyogenesisolated from the PROTEKT 1999-2000 study
-
Farrell DJ, Morrissey I, Bakker S, et al. Molecular characterization of macrolide resistance mechanisms among Streptococcus pneumoniaeandStreptococcus pyogenesisolated from the PROTEKT 1999-2000 study. J Antimicrob Chemother 2002; 50: Suppl. S1, 39-47.
-
(2002)
J Antimicrob Chemother
, vol.50
, Issue.SUPPL. S1
, pp. 39-47
-
-
Farrell, D.J.1
Morrissey, I.2
Bakker, S.3
-
85
-
-
0346025671
-
Antimicrobial susceptibility among community-acquired respiratory tract pathogens in the USA: Data from PROTEKT US 2000-01
-
Doern GV, Brown SD. Antimicrobial susceptibility among community-acquired respiratory tract pathogens in the USA: data from PROTEKT US 2000-01. J Infect 2004; 48: 56-65.
-
(2004)
J Infect
, vol.48
, pp. 56-65
-
-
Doern, G.V.1
Brown, S.D.2
-
86
-
-
19244365446
-
Oral erythromycin and the risk of sudden death from cardiac causes
-
Ray WA, Murray KT, Meredith S, et al. Oral erythromycin and the risk of sudden death from cardiac causes. N Engl J Med 2004; 351: 1089-1096.
-
(2004)
N Engl J Med
, vol.351
, pp. 1089-1096
-
-
Ray, W.A.1
Murray, K.T.2
Meredith, S.3
-
88
-
-
84861076083
-
Azithromycin and the risk of cardiovascular death
-
Ray WA, Murray KT, Hall K, et al. Azithromycin and the risk of cardiovascular death. N Engl J Med 2012; 366: 1881-1890.
-
(2012)
N Engl J Med
, vol.366
, pp. 1881-1890
-
-
Ray, W.A.1
Murray, K.T.2
Hall, K.3
-
89
-
-
30344454405
-
Randomised placebo controlled multicentre trial to assess short term clarithromycin for patients with stable coronary heart disease: CLARICOR trial
-
Jespersen CM, Als-Nielsen B, Damgaard M, et al. Randomised placebo controlled multicentre trial to assess short term clarithromycin for patients with stable coronary heart disease: CLARICOR trial. BMJ2006; 332: 22-27.
-
(2006)
BMJ
, vol.332
, pp. 22-27
-
-
Jespersen, C.M.1
Als-Nielsen, B.2
Damgaard, M.3
-
90
-
-
84876129813
-
Cardiovascular events after clarithromycin use in lower respiratory tract infections: Analysis of two prospective cohort studies
-
Schembri S, Williamson PA, Short PM, et al. Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies. BMJ2013; 346: f1235.
-
(2013)
BMJ
, vol.346
-
-
Schembri, S.1
Williamson, P.A.2
Short, P.M.3
-
91
-
-
84865306933
-
Azithromycin and the risk of cardiovascular death
-
Albert RK, Connett J, Woodruff PG. Azithromycin and the risk of cardiovascular death. N Engl J Med 2012; 367: 773-774.
-
(2012)
N Engl J Med
, vol.367
, pp. 773-774
-
-
Albert, R.K.1
Connett, J.2
Woodruff, P.G.3
-
92
-
-
0022387422
-
Drug interactions and hepatitis produced by some macrolide antibiotics
-
Pessayre D, Larrey D, Funck-Brentano C, et al. Drug interactions and hepatitis produced by some macrolide antibiotics. J Antimicrob Chemother 1985; 16: Suppl. A, 181-194.
-
(1985)
J Antimicrob Chemother
, vol.16
, Issue.SUPPL. A
, pp. 181-194
-
-
Pessayre, D.1
Larrey, D.2
Funck-Brentano, C.3
-
93
-
-
13144257695
-
Inhibition of triazolam clearance by macrolide antimicrobial agents: In vitro correlates and dynamic consequences
-
Greenblatt DJ, von Moltke LL, Harmatz JS, et al. Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. Clin Pharmacol Ther 1998; 64: 278-285.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 278-285
-
-
Greenblatt, D.J.1
von Moltke, L.L.2
Harmatz, J.S.3
-
94
-
-
0031670167
-
Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations
-
Kantola T, Kivistö KT, Neuvonen PJ. Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther 1998; 64: 177-182.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 177-182
-
-
Kantola, T.1
Kivistö, K.T.2
Neuvonen, P.J.3
-
95
-
-
0029130840
-
Macrolide antibacterials. Drug interactions of clinical significance
-
Von Rosensteil NA, Adam D. Macrolide antibacterials. Drug interactions of clinical significance. Drug Saf 1995; 13: 105-122.
-
(1995)
Drug Saf
, vol.13
, pp. 105-122
-
-
Von Rosensteil, N.A.1
Adam, D.2
|