Solution-based indirect affinity selection mass spectrometry-A general tool for high-throughput screening of pharmaceutical compound libraries

Analytical Chemistry

Volumn 86, Issue 15, 2014, Pages 7413-7420

  O'Connell, Thomas N ^a   Ramsay, Jason ^a   Rieth, Steven F ^a   Shapiro, Michael J ^a   Stroh, Justin G ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ANALYSIS; CHEMISTRY;

AFFINITY SELECTION; BINDING ASSAYS; DEVELOPMENT TIME; EXACT MASS; GENERAL TOOLS; HIGH-THROUGHPUT SCREENING; HIT RATE; PHARMACEUTICAL COMPOUNDS;

MASS SPECTROMETRY;

EID: 84905694080     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac500938y     Document Type: Article

References (26)

1. Wunder, F.; Kalthof, B.; Mueller, T.; Hueser, J. Comb. Chem. High Throughput Screening 2008, 11, 495-504
2. Macarron, R.; Banks, M. N.; Bojanic, D.; Burns, D. J.; Cirovic, D. A.; Garyantes, T.; Green, D. V. S.; Hertzberg, R. P.; Janzen, W. P.; Paslay, J. W.; Schopfer, U.; Sittampalam, G. S. Nat. Rev. Drug Discovery 2011, 10, 188-195
3. Sink, R.; Gobec, S.; Pecar, S.; Zega, A. Curr. Med. Chem. 2010, 17, 4231-4255
4. Shun, T. Y.; Lazo, J. S.; Sharlow, E. R.; Johnston, P. A. J. Biomol. Screening 2011, 16, 1-14
5. Malo, N.; Hanley, J. A.; Cerquozzi, S.; Pelletier, J.; Nadon, R. Nat. Biotechnol. 2006, 24, 167-175
6. van Breemen, R. B.; Huang, C.-R.; Nikolic, D.; Woodbury, C. P.; Zhao, Y.-Z.; Venton, D. L. Anal. Chem. 1997, 69, 2159-2164
7. Andrews, C. L.; Ziebell, M. R.; Nickbarg, E.; Yang, X. Protein and Peptide Mass Spectrometry in Drug Discovery; John Wiley & Sons, Inc.: Hoboken, NJ, 2012; pp 255-286, 252 plates.
8. Shin, Y. G.; Van Breemen, R. B. Biopharm. Drug Dispos. 2001, 22, 353-372
9. Siegel, M. M. Curr. Top. Med. Chem. (Hilversum, Neth.) 2002, 2, 13-33
10. Brown, N.; Zehender, H.; Azzaoui, K.; Schuffenhauer, A.; Mayr, L. M.; Jacoby, E. J. Biomol. Screening 2006, 11, 123-130
11. Zehender, H.; Mayr, L. M. Expert Opin. Drug Discovery 2007, 2, 285-294
12. Johnson, B. M.; Nikolic, D.; van Breemen, R. B. Mass Spectrom. Rev. 2002, 21, 76-86
13. Comess, K. M.; Schurdak, M. E.; Voorbach, M. J.; Coen, M.; Trumbull, J. D.; Yang, H.; Gao, L.; Tang, H.; Cheng, X.; Lerner, C. G.; McCall, J. O.; Burns, D. J.; Beutel, B. A. J. Biomol. Screening 2006, 11, 743-754
14. Comess, K. M.; Trumbull, J. D.; Park, C.; Chen, Z.; Judge, R. A.; Voorbach, M. J.; Coen, M.; Gao, L.; Tang, H.; Kovar, P.; Cheng, X.; Schurdak, M. E.; Zhang, H.; Sowin, T.; Burns, D. J. J. Biomol. Screening 2006, 11, 755-764
15. Brown, N.; Zehender, H.; Azzaoui, K.; Schuffenhauer, A.; Mayr, L. M.; Jacoby, E. J. Biomol. Screening 2006, 11, 123-130
16. Muckenschnabel, I.; Falchetto, R.; Mayr, L. M.; Filipuzzi, I. Anal. Biochem. 2004, 324, 241-249
17. Annis, D. A.; Athanasopoulos, J.; Curran, P. J.; Felsch, J. S.; Kalghatgi, K.; Lee, W. H.; Nash, H. M.; Orminati, J.-P. A.; Rosner, K. E.; Shipps, G. W.; Thaddupathy, G. R. A.; Tyler, A. N.; Vilenchik, L.; Wagner, C. R.; Wintner, E. A. Int. J. Mass Spectrom. 2004, 238, 77-83
18. Annis, D. A.; Nazef, N.; Chuang, C.-C.; Scott, M. P.; Nash, H. M. J. Am. Chem. Soc. 2004, 126, 15495-15503
19. Annis, D. A.; Nickbarg, E.; Yang, X.; Ziebell, M. R.; Whitehurst, C. E. Curr. Opin. Chem. Biol. 2007, 11, 518-526
20. Annis, D. A.; Shipps, G. W., Jr.; Deng, Y.; Popovici-Mueller, J.; Siddiqui, M. A.; Curran, P. J.; Gowen, M.; Windsor, W. T. Anal. Chem. (Washington, DC, U. S.) 2007, 79, 4538-4542
21. Annis, A.; Chuang, C.-C.; Nazef, N. Methods Princ. Med. Chem. 2007, 36, 121-156
22. Supuran, C. T.; Scozzafava, A.; Casini, A. Med. Res. Rev. 2003, 23, 146-189
23. Copeland, R. A.; Pompliano, D. L.; Meek, T. D. Nat. Rev. Drug Discovery 2006, 5, 730-739
24. Swinney, D. C. Annu. Rep. Med. Chem. 2011, 46, 301-317 301 plate.
25. Maren, T. H. Mol. Pharmacol. 1992, 41, 419-426
26. Navratilova, I.; Papalia, G. A.; Rich, R. L.; Bedinger, D.; Brophy, S.; Condon, B.; Deng, T.; Emerick, A. W.; Guan, H.-W.; Hayden, T.; Heutmekers, T.; Hoorelbeke, B.; McCroskey, M. C.; Murphy, M. M.; Nakagawa, T.; Parmeggiani, F.; Qin, X.; Rebe, S.; Tomasevic, N.; Tsang, T.; Waddell, M. B.; Zhang, F. F.; Leavitt, S.; Myszka, D. G. Anal. Biochem. 2007, 364, 67-77