Application of high-throughput affinity-selection mass spectrometry for screening of chemical compound libraries in lead discovery

Expert Opinion on Drug Discovery

Volumn 2, Issue 2, 2007, Pages 285-294

  Zehender, Hartmut ^a   Mayr, Lorenz M ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Affinity selection; Assay technology; Chemical binders; High throughput screening; Label free; Mass spectrometry; Primary assay

Indexed keywords

BIOTIN; CHEMICAL COMPOUND; CYCLIC AMP DEPENDENT PROTEIN KINASE; ETHOXZOLAMIDE; STAUROSPORINE; STREPTAVIDIN; UREA; WARFARIN;

AFFINITY CHROMATOGRAPHY; BINDING AFFINITY; BIOTECHNOLOGY; DRUG INDUSTRY; DRUG RESEARCH; DRUG TARGETING; GENE TARGETING; HIGH THROUGHPUT SCREENING; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR BIOLOGY; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVIEW; SEPARATION TECHNIQUE;

EID: 34447509220     PISSN: 17460441     EISSN: None     Source Type: Journal    
DOI: 10.1517/17460441.2.2.285     Document Type: Review

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