메뉴 건너뛰기




Volumn 64, Issue , 2014, Pages 500-507

A dose-response study of the bioavailability of grape seed proanthocyanidin in rat and lipid-lowering effects of generated metabolites in HepG2 cells

Author keywords

Cholesterol; HPLC MS MS; Polyphenols; Proanthocyanidins; Triglycerides

Indexed keywords

BIOCHEMISTRY; BIOMOLECULES; BODY FLUIDS; CELLS; CHOLESTEROL; CYTOLOGY; LIPIDS; METABOLITES; PHYSIOLOGY; RATS;

EID: 84905649151     PISSN: 09639969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodres.2014.07.019     Document Type: Article
Times cited : (26)

References (38)
  • 2
    • 0036270096 scopus 로고    scopus 로고
    • Red wine phenolic compounds reduce plasma lipids and apolipoprotein B and prevent early aortic atherosclerosis in hypercholesterolemic golden Syrian hamsters (Mesocricetus auratus)
    • Auger C., Caporiccio B., Landrault N., Teissedre P.L., Laurent C., Cros G., et al. Red wine phenolic compounds reduce plasma lipids and apolipoprotein B and prevent early aortic atherosclerosis in hypercholesterolemic golden Syrian hamsters (Mesocricetus auratus). Journal of Nutrition 2002, 132(6):1207-1213.
    • (2002) Journal of Nutrition , vol.132 , Issue.6 , pp. 1207-1213
    • Auger, C.1    Caporiccio, B.2    Landrault, N.3    Teissedre, P.L.4    Laurent, C.5    Cros, G.6
  • 3
    • 48449083346 scopus 로고    scopus 로고
    • Microbial metabolism of dietary phenolic compounds in the colon
    • Aura A.M. Microbial metabolism of dietary phenolic compounds in the colon. Phytochemistry Reviews 2008, 7(3):407-429.
    • (2008) Phytochemistry Reviews , vol.7 , Issue.3 , pp. 407-429
    • Aura, A.M.1
  • 4
    • 84880806221 scopus 로고    scopus 로고
    • Chronic administration of proanthocyanidins or docosahexaenoic acid reverses the increase of miR-33a and miR-122 in dyslipidemic obese rats
    • Baselga-Escudero L., Arola-Arnal A., Pascual-Serrano A., Ribas-Latre A., Casanova E., Salvadó M.-J., et al. Chronic administration of proanthocyanidins or docosahexaenoic acid reverses the increase of miR-33a and miR-122 in dyslipidemic obese rats. PloS One 2013, 8(7):e69817.
    • (2013) PloS One , vol.8 , Issue.7
    • Baselga-Escudero, L.1    Arola-Arnal, A.2    Pascual-Serrano, A.3    Ribas-Latre, A.4    Casanova, E.5    Salvadó, M.-J.6
  • 5
    • 74349097440 scopus 로고    scopus 로고
    • Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms
    • Bladé C., Arola L., Salvadó M.J. Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms. Molecular Nutrition & Food Research 2010, 54(1):37-59.
    • (2010) Molecular Nutrition & Food Research , vol.54 , Issue.1 , pp. 37-59
    • Bladé, C.1    Arola, L.2    Salvadó, M.J.3
  • 6
    • 77956716582 scopus 로고    scopus 로고
    • Dietary polyphenols: Focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis
    • Borriello A., Cucciolla V., Della Ragione F., Galletti P. Dietary polyphenols: Focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis. Nutrition, Metabolism, and Cardiovascular Diseases 2010, 20(8):618-625.
    • (2010) Nutrition, Metabolism, and Cardiovascular Diseases , vol.20 , Issue.8 , pp. 618-625
    • Borriello, A.1    Cucciolla, V.2    Della Ragione, F.3    Galletti, P.4
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976, 72(1):248-254.
    • (1976) Analytical Biochemistry , vol.72 , Issue.1 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 68149124472 scopus 로고    scopus 로고
    • Dietary phenolics: Chemistry, bioavailability and effects on health
    • Crozier A., Jaganath I.B., Clifford M.N. Dietary phenolics: Chemistry, bioavailability and effects on health. Natural Product Reports 2009, 26(8):1001-1043.
    • (2009) Natural Product Reports , vol.26 , Issue.8 , pp. 1001-1043
    • Crozier, A.1    Jaganath, I.B.2    Clifford, M.N.3
  • 9
    • 84862748467 scopus 로고    scopus 로고
    • Detection of bioavailable peroxisome proliferator-activated receptor gamma modulators by a cell-based luciferase reporter system
    • Del Bas J.M., Laos S., Caimari A., Crescenti A., Arola L. Detection of bioavailable peroxisome proliferator-activated receptor gamma modulators by a cell-based luciferase reporter system. Analytical Biochemistry 2012, 427:187-189.
    • (2012) Analytical Biochemistry , vol.427 , pp. 187-189
    • Del Bas, J.M.1    Laos, S.2    Caimari, A.3    Crescenti, A.4    Arola, L.5
  • 10
  • 11
    • 68149123902 scopus 로고    scopus 로고
    • Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner
    • Del Bas J.M., Ricketts M.L., Vaqué M., Sala E., Quesada H., Ardevol A., et al. Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner. Molecular Nutrition & Food Research 2009, 53(7):805-814.
    • (2009) Molecular Nutrition & Food Research , vol.53 , Issue.7 , pp. 805-814
    • Del Bas, J.M.1    Ricketts, M.L.2    Vaqué, M.3    Sala, E.4    Quesada, H.5    Ardevol, A.6
  • 12
    • 84875953344 scopus 로고    scopus 로고
    • Dietary (poly)phenolics in human health: Structures, bioavailability, and evidence of protective effects against chronic diseases
    • Del Rio D., Rodriguez-Mateos A., Spencer J.P.E., Tognolini M., Borges G., Crozier A. Dietary (poly)phenolics in human health: Structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxidants & Redox Signaling 2013, 18(14):1818-1892.
    • (2013) Antioxidants & Redox Signaling , vol.18 , Issue.14 , pp. 1818-1892
    • Del Rio, D.1    Rodriguez-Mateos, A.2    Spencer, J.P.E.3    Tognolini, M.4    Borges, G.5    Crozier, A.6
  • 15
    • 0028925089 scopus 로고
    • Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study
    • Hertog M.G., Kromhout D., Aravanis C., Blackburn H., Buzina R., Fidanza F., et al. Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. Archives of Internal Medicine 1995, 155(4):381-386.
    • (1995) Archives of Internal Medicine , vol.155 , Issue.4 , pp. 381-386
    • Hertog, M.G.1    Kromhout, D.2    Aravanis, C.3    Blackburn, H.4    Buzina, R.5    Fidanza, F.6
  • 16
    • 0036257531 scopus 로고    scopus 로고
    • Comparative study of concentration of isoflavones and lignans in plasma and prostatic tissues of normal control and benign prostatic hyperplasia
    • Hong S.J., Kim S.Il, Kwon S.M., Lee J.R., Chung B.C. Comparative study of concentration of isoflavones and lignans in plasma and prostatic tissues of normal control and benign prostatic hyperplasia. Yonsei Medical Journal 2002, 43(2):236-241.
    • (2002) Yonsei Medical Journal , vol.43 , Issue.2 , pp. 236-241
    • Hong, S.J.1    Kim, S.I.2    Kwon, S.M.3    Lee, J.R.4    Chung, B.C.5
  • 17
    • 78049422948 scopus 로고    scopus 로고
    • The future of flavonoid research
    • Kay C.D. The future of flavonoid research. British Journal of Nutrition 2010, 104:S91-S95.
    • (2010) British Journal of Nutrition , vol.104
    • Kay, C.D.1
  • 20
    • 0346668361 scopus 로고    scopus 로고
    • Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography
    • Maubach J., Bracke M.E., Heyerick A., Depypere H.T., Serreyn R.F., Mareel M.M., et al. Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography. Journal of Chromatography B 2003, 784(1):137-144.
    • (2003) Journal of Chromatography B , vol.784 , Issue.1 , pp. 137-144
    • Maubach, J.1    Bracke, M.E.2    Heyerick, A.3    Depypere, H.T.4    Serreyn, R.F.5    Mareel, M.M.6
  • 21
    • 79951609639 scopus 로고    scopus 로고
    • Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites
    • Monagas M., Urpi-Sarda M., Sánchez-Patán F., Llorach R., Garrido I., Gómez-Cordovés C., et al. Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites. Food & Function 2010, 1(3):233-253.
    • (2010) Food & Function , vol.1 , Issue.3 , pp. 233-253
    • Monagas, M.1    Urpi-Sarda, M.2    Sánchez-Patán, F.3    Llorach, R.4    Garrido, I.5    Gómez-Cordovés, C.6
  • 22
    • 10744225301 scopus 로고    scopus 로고
    • Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial
    • Nissen S.E., Tuzcu E.M., Schoenhagen P., Brown B.G., Ganz P., Vogel R.A., et al. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial. JAMA: The Journal of the American Medical Association 2004, 291(9):1071-1080.
    • (2004) JAMA: The Journal of the American Medical Association , vol.291 , Issue.9 , pp. 1071-1080
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3    Brown, B.G.4    Ganz, P.5    Vogel, R.A.6
  • 23
    • 0037300834 scopus 로고    scopus 로고
    • Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: The role of human β-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism
    • O'Leary K.A., Day A.J., Needs P.W., Mellon F.A., O'Brien N.M., Williamson G. Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: The role of human β-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism. Biochemical Pharmacology 2003, 65(3):479-491.
    • (2003) Biochemical Pharmacology , vol.65 , Issue.3 , pp. 479-491
    • O'Leary, K.A.1    Day, A.J.2    Needs, P.W.3    Mellon, F.A.4    O'Brien, N.M.5    Williamson, G.6
  • 25
    • 0037369915 scopus 로고    scopus 로고
    • Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of ApoB100 from human HepG2 cells
    • Pal S., Ho N., Santos C., Dubois P., Mamo J., Croft K., et al. Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of ApoB100 from human HepG2 cells. The Journal of Nutrition 2003, 133(3):700-706.
    • (2003) The Journal of Nutrition , vol.133 , Issue.3 , pp. 700-706
    • Pal, S.1    Ho, N.2    Santos, C.3    Dubois, P.4    Mamo, J.5    Croft, K.6
  • 27
    • 59649090878 scopus 로고    scopus 로고
    • Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extract
    • Prasain J.K., Peng N., Dai Y., Moore R., Arabshahi A., Wilson L., et al. Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extract. Phytomedicine 2009, 16(2):233-243.
    • (2009) Phytomedicine , vol.16 , Issue.2 , pp. 233-243
    • Prasain, J.K.1    Peng, N.2    Dai, Y.3    Moore, R.4    Arabshahi, A.5    Wilson, L.6
  • 28
    • 70349119490 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver
    • (2005)
    • Quesada H., del Bas J.M., Pajuelo D., Díaz S., Fernandez-Larrea J., Pinent M., et al. Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver. International Journal of Obesity 2009, 33:1007-1012. (2005).
    • (2009) International Journal of Obesity , vol.33 , pp. 1007-1012
    • Quesada, H.1    del Bas, J.M.2    Pajuelo, D.3    Díaz, S.4    Fernandez-Larrea, J.5    Pinent, M.6
  • 29
    • 84873926187 scopus 로고    scopus 로고
    • Low-molecular procyanidin rich grape seed extract exerts antihypertensive effect in males spontaneously hypertensive rats
    • Quiñones M., Guerrero L., Suarez M., Pons Z., Aleixandre A., Arola L., et al. Low-molecular procyanidin rich grape seed extract exerts antihypertensive effect in males spontaneously hypertensive rats. Food Research International 2013, 51(2):587-595.
    • (2013) Food Research International , vol.51 , Issue.2 , pp. 587-595
    • Quiñones, M.1    Guerrero, L.2    Suarez, M.3    Pons, Z.4    Aleixandre, A.5    Arola, L.6
  • 30
    • 15044340025 scopus 로고    scopus 로고
    • Dietary proanthocyanidins: occurrence, dietary intake, bioavailability, and protection against cardiovascular disease
    • Rasmussen S.E., Frederiksen H., Struntze Krogholm K., Poulsen L. Dietary proanthocyanidins: occurrence, dietary intake, bioavailability, and protection against cardiovascular disease. Molecular Nutrition & Food Research 2005, 49(2):159-174.
    • (2005) Molecular Nutrition & Food Research , vol.49 , Issue.2 , pp. 159-174
    • Rasmussen, S.E.1    Frederiksen, H.2    Struntze Krogholm, K.3    Poulsen, L.4
  • 32
    • 77951209860 scopus 로고    scopus 로고
    • Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models
    • Serra A., Macià A., Romero M.P., Valls J., Bladé C., Arola L., et al. Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models. British Journal of Nutrition 2010, 103(07):944-952.
    • (2010) British Journal of Nutrition , vol.103 , Issue.7 , pp. 944-952
    • Serra, A.1    Macià, A.2    Romero, M.P.3    Valls, J.4    Bladé, C.5    Arola, L.6
  • 33
    • 84879552495 scopus 로고    scopus 로고
    • Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams
    • Serra A., Macià A., Rubió L., Anglès N., Ortega N., Morelló J.R., et al. Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams. European Journal of Nutrition 2013, 52(3):1029-1038.
    • (2013) European Journal of Nutrition , vol.52 , Issue.3 , pp. 1029-1038
    • Serra, A.1    Macià, A.2    Rubió, L.3    Anglès, N.4    Ortega, N.5    Morelló, J.R.6
  • 34
    • 79959230734 scopus 로고    scopus 로고
    • Bioavailability of dietary polyphenols and the cardiovascular diseases
    • Shivashankara K.S., Acharya S.N. Bioavailability of dietary polyphenols and the cardiovascular diseases. The Open Nutraceuticals Journal 2010, 3:227-241.
    • (2010) The Open Nutraceuticals Journal , vol.3 , pp. 227-241
    • Shivashankara, K.S.1    Acharya, S.N.2
  • 36
    • 0035022276 scopus 로고    scopus 로고
    • Red wine, dealcoholized red wine, and especially grape juice, inhibit atherosclerosis in a hamster model
    • Vinson J.A., Teufel K., Wu N. Red wine, dealcoholized red wine, and especially grape juice, inhibit atherosclerosis in a hamster model. Atherosclerosis 2001, 156(1):67-72.
    • (2001) Atherosclerosis , vol.156 , Issue.1 , pp. 67-72
    • Vinson, J.A.1    Teufel, K.2    Wu, N.3
  • 37
    • 81455149976 scopus 로고    scopus 로고
    • Effects of hesperidin on the progression of hypercholesterolemia and fatty liver induced by high-cholesterol diet in rats
    • Wang X., Hasegawa J., Kitamura Y., Wang Z., Matsuda A., Shinoda W., et al. Effects of hesperidin on the progression of hypercholesterolemia and fatty liver induced by high-cholesterol diet in rats. Journal of Pharmacological Sciences 2011, 117(3):129-138.
    • (2011) Journal of Pharmacological Sciences , vol.117 , Issue.3 , pp. 129-138
    • Wang, X.1    Hasegawa, J.2    Kitamura, Y.3    Wang, Z.4    Matsuda, A.5    Shinoda, W.6
  • 38
    • 84862830821 scopus 로고    scopus 로고
    • Bioactivity-guided fractionation of the triglyceride-lowering component and in vivo and in vitro evaluation of hypolipidemic effects of Calyx seu fructus physalis
    • Yang Y., Piao X., Zhang M., Wang X., Xu B., Zhu J., et al. Bioactivity-guided fractionation of the triglyceride-lowering component and in vivo and in vitro evaluation of hypolipidemic effects of Calyx seu fructus physalis. Lipids in Health and Disease 2012, 11(1):38-45.
    • (2012) Lipids in Health and Disease , vol.11 , Issue.1 , pp. 38-45
    • Yang, Y.1    Piao, X.2    Zhang, M.3    Wang, X.4    Xu, B.5    Zhu, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.