Bone marrow mesenchymal stromal cells affect the cell cycle arrest effect of genotoxic agents on acute lymphocytic leukemia cells via p21 down-regulation

Annals of Hematology

Volumn 93, Issue 9, 2014, Pages 1499-1508

  Zhang, Yiran ^a   Hu, Kaimin ^a   Hu, Yongxian ^a   Liu, Lizhen ^a   Wang, Binsheng ^a   Huang, He ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Acute lymphoblastic leukemia; Bone marrow mesenchymal stromal cells; Cell cycle; Drug resistance; p21

Indexed keywords

BETA CATENIN; PROTEIN P21; WNT PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; APOPTOSIS; ARTICLE; BONE MARROW; BONE MARROW MESENCHYMAL STROMAL CELL; CELL CYCLE ARREST; CONTROLLED STUDY; DOWN REGULATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LEUKEMIA CELL; MESENCHYMAL STROMA CELL; PRIORITY JOURNAL; S PHASE CELL CYCLE CHECKPOINT; WNT SIGNALING PATHWAY;

ADOLESCENT; ANTINEOPLASTIC AGENTS; BONE MARROW CELLS; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; MESENCHYMAL STROMAL CELLS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

EID: 84905580103     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-014-2069-1     Document Type: Article

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