Loss of Thy-1 (CD90) antigen expression on mesenchymal stromal cells from hematologic malignancies is induced by in vitro angiogenic stimuli and is associated with peculiar functional and phenotypic characteristics

Cytotherapy

Volumn 10, Issue 1, 2008, Pages 69-82

  Campioni, D ^a   Lanza, F ^a   Moretti, S ^a   Ferrari, L ^a   Cuneo, A ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

Angiogenesis; Bone marrow mesenchymal cells; Flow cytometry; Hematologic disorders; Immunophenotypic subsets; Microenvironment

Indexed keywords

ADAPALENE; THY 1 ANTIGEN;

ADIPOCYTE; ADOLESCENT; ADULT; ANGIOGENESIS; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CLONOGENESIS; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; FLOW CYTOMETRY; HEMATOLOGIC MALIGNANCY; HEMATOPOIESIS; HUMAN; IMMUNOPHENOTYPING; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL;

EID: 38349095329     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1080/14653240701762364     Document Type: Article

References (41)

1. Horwitz, EM, Blanc, K Le and Dominici, M. (2005) Clarification of the nomenclature of MSC: The International Society for Cellular Therapy position statement. Cytotherapy, 7, pp. 393-395.
2. Orkin, SH. (2000) Stem cell alchemy. Nat Med, 6, pp. 1212-1213.
3. Wulf, GG, Jackson, KA and Goodell, MA. (2001) Somatic stem cell plasticity: Current evidence and emerging concepts. Exp Hematol, 9, pp. 1361-1370.
4. Pittenger, M., Mackay, A. and Beck, S. (2000) Multilineage potential of adult human mesenchymal stem cells. Science, 284, pp. 143-147.
5. Reyes, M., Lund, T. and Lenvik, T. (2001) Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood, 98, pp. 2615-2625.
6. Nicola, M Di, Carlo-Stella, C. and Magni, M. (2000) Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood, 99, pp. 3838-3843.
7. Blanc, K Le, Tammik, C. and Rosendahl, K. (2003) HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal cells. Exp Hematol, 31, pp. 890-896.
8. Almeida-Porada, G., Flake, AW and Glimp, HA (1999) Cotransplantation of stroma results in enhancement of engraftment and early expression of donor hematopoietic stem cells in utero. Exp Hematol, 27, pp. 1569-1575.
9. Devine, SM, Cobbs, C. and Jennings, M. (2003) Mesenchymal stem cells distribute to a wide range of tissue following systemic infusion into nonhuman primates. Blood, 101, pp. 2999-3001.
10. Horwitz, EM, Gordon, PL and Koo, WKK (2002) Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone. Proc Natl Acad Sci USA, 99, pp. 8932-8937.
11. Rafii, S. and Lyden, D. (2003) Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med, 9, pp. 702-712.
12. Oswald, J., Boxberger, S. and Jorgensen, B. (2004) Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells, 22, pp. 377-384.
13. Ventura, C., Cantoni, S. and Bianchi, F. (2007) Hyaluronan mixed esters of butyric and retinoic acid drive cardiac and endothelial fate in term placenta human mesenchymal cells and enhance cardiac repair in infracted rat hearts. JBC
14. Berry, MF, Engler, AJ and Woo, YJ (2006) Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. Am J Physiol Heart Circ Physiol, 290, pp. 2196-2203.
15. Gregory, CA, Ylostalo, J. and Prockop, DJ. (2005) Adult bone marrow stem/ progenitor cells (MSCs) are preconditioned by microenvironmental 'niches' in culture: A two stage hypothesis for regulation of MSC fate. Sci STKE, 294, p. 37.
16. Girolamo, CM Di, Stokes, D. and Colter, D. (1999) Propagation and senescence of human marrow stromal cells in culture: A simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. Br J Haematol, 107, pp. 275-281.
17. Meuleman, N., Tondreau, T. and Delforge, A. (2006) Human marrow mesenchymal stem cell culture: Serum-free medium allows better expansion than classical a-MEM medium. Eur J Haematol, 76, pp. 309-316.
18. Mueller, I., Kordowich, S. and Holzwarth, C. (2006) Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM. Cytotherapy, 8, pp. 437-444.
19. Sotiropoulou, PA, Perez, SA and Salagianni, M. (2006) Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells, 24, pp. 74-85.
20. Lanza, F., Campioni, D. and Moretti, S. (2007) Aberrant expression of HLA-DR antigen by bone marrow-derived mesenchymal stromal cells from patients affected by acute lymphoproliferative disorders. Leukemia, 21, pp. 378-381.
21. Tremain, N., Korkko, J. and Ibberson, D. (2001) Micro-SAGE analysis of 2,353 expressed genes in a single cell derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages. Stem Cells, 19, pp. 408-418.
22. Götherström, C., West, A. and Liden, J. (2005) Differences in gene expression between human fetal liver and adult bone marrow mesenchymal stem cells. Haematologica, 90, pp. 1017-1026.
23. Wagner, W., Wein, F. and Seckinger, A. (2005) Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. Exp Hematol, 11, pp. 1402-1416.
24. Campioni, D., Moretti, S. and Ferrari, L. (2006) Immunophenotypic heterogeneity of bone marrow-derived mesenchymal stromal cells from patients with hematologic disorders: Correlation with bone marrow microenvironment. Haematologica, 91, pp. 364-368.
25. Castro-Malaspina, H., Gay, RE and Resnick, G. (1980) Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny. Blood, 56, pp. 289-301.
26. Shibata, A., Bennet, JM and Castoldi, GL (1985) Recommended methods for cytological procedures in haematology. Clin Lab Haematol, 7, pp. 55-74.
27. Lanza, F., Latorraca, A. and Moretti, S. (1999) Trattato Italiano di Medicina di Laboratorio, Padova
28. Lanza, F., Campioni, D. and Moretti, S. (2001) CD34+ cell subsets and long-term culture colony-forming cells evaluated on both autologous and normal bone marrow stroma predict long-term hemopoietic engraftment in patients undergoing autologous peripheral blood stem cell transplantation. Exp Hematol, 29, pp. 1-10.
29. Chang, H., Chi, JT and Dudoit, S. (2002) Diversity, topographic differentiation, and positional memory in human fibroblasts. Proc Natl Acad Sci USA, 99, pp. 12877-12882.
30. Peister, A., Mellad, JA and Larson, BL (2004) Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood, 103, pp. 1662-1668.
31. Anker, PS In'T, Noort, WA and Sherjon, SA (2003) Mesenchymal stem cells in human second-trimester bone marrow, liver, lung and spleen exhibit a similar immunophenotype but heterogenous multilineage differentiation potential. Haematologica, 88, pp. 845-852.
32. Majumdar, MK, Keane-Moore, M. and Buyaner, D. (2003) Characterization and functionality of cell surface molecules on human mesenchymal stem cells. J Biomed Sci, 10, pp. 228-241.
33. Conget, PA and Minguell, JJ. (1999) Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol, 181, pp. 67-73.
34. Bhuring, HJ, Kuci, S. and Conze, T. (2004) CDCP1 identifies a broad spectrum of normal and malignant stem/progenitor cell subsets of hematopoietic and non-hematopoietic origin. Stem Cells, 22, pp. 334-343.
35. Vogel, W., Grunebach, F. and Messam, CA (2003) Heterogeneity among human bone marrow derived mesenchymal stem cells and neural progenitors. Haematologica, 88, pp. 126-132.
36. Sordi, V., Malosio, ML and Marchesi, F. (2005) Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islet. Blood, 106, pp. 419-425.
37. Lee, RH, Hsu, SC and Munoz, J. (2006) A subset of human rapidly-self renewing marrow stromal cells (MSCs) preferentially engraft in mice. Blood, 107, pp. 2153-2161.
38. Koumas, L., Smith, TJ and Phipps, RP. (2002) Fibroblast subset in the human orbit: Thy-1+ and Thy-1- subpopulations exhibit distinct phenotypes. Eur J Immunol, 32, pp. 477-485.
39. Koumas, L., King, AE and Critchley, HOD (2001) Existence of functionally distinct Thy-1 and Thy-1- human female reproductive tract fibroblasts. Am J Pathol, 159, pp. 925-935.
40. Quirici, N., Soligo, D. and Bossolasco, P. (2002) Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodies. Exp Hematol, 30, pp. 783-791.
41. Meyer, H., Bertram, H. and Lindenmaier, W. (2005) Vascular endothelial growth factor (VEGF-A) expression in human mesenchymal stem cells: autocrine and paracrine role on osteoblastic and endothelial differentiation. J Cell Biochem, 95, pp. 827-839.