Hydrogels with differential and patterned mechanics to study stiffness-mediated myofibroblastic differentiation of hepatic stellate cells

Journal of the Mechanical Behavior of Biomedical Materials

Volumn 38, Issue , 2014, Pages 198-208

  Guvendiren, Murat ^a   Perepelyuk, Maryna ^b   Wells, Rebecca G ^b   Burdick, Jason A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMECHANICS; CELLS; CYTOLOGY; DROPS; PROTEINS; STIFFNESS; SUBSTRATES; TISSUE;

CELLULAR RESPONSE; DIFFERENTIATED CELLS; EXTRACELLULAR MATRICES; HEPATIC STELLATE CELLS; HYDROGEL CROSSLINKING; LOCAL STIFFENING; SMOOTH MUSCLE ACTINS; TUNABLE STIFFNESS;

HYDROGELS;

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; FAT DROPLET; METHACRYLIC ACID DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSFORMING GROWTH FACTOR BETA1; HYALURONIC ACID; HYDROGEL; THIOL DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL SPREADING; CONTROLLED STUDY; CROSS LINKING; HYDROGEL; LIVER; MACROMOLECULE; MICHAEL ADDITION; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STELLATE CELL; ULTRAVIOLET RADIATION; ANIMAL; BIOMECHANICS; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; LIVER CIRRHOSIS; MECHANICS; PATHOLOGY; PHARMACOLOGY; YOUNG MODULUS;

ANIMALS; BIOMECHANICAL PHENOMENA; CELL DIFFERENTIATION; ELASTIC MODULUS; HEPATIC STELLATE CELLS; HYALURONIC ACID; HYDROGELS; LIVER CIRRHOSIS; MECHANICAL PROCESSES; METHACRYLATES; MYOFIBROBLASTS; PPAR GAMMA; RATS; SULFHYDRYL COMPOUNDS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84905576151     PISSN: 17516161     EISSN: 18780180     Source Type: Journal    
DOI: 10.1016/j.jmbbm.2013.11.008     Document Type: Article

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