Co-transcriptional recruitment of Puf6 by She2 couples translational repression to mRNA localization

Nucleic Acids Research

Volumn 42, Issue 13, 2014, Pages 8692-8704

  Shahbabian, Karen ^a   Jeronimo, Célia ^b   Forget, Amélie ^a   Robert, François ^a,b   Chartrand, Pascal ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LOC1 PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; PUF6 PROTEIN; SHE2 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MASH1; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CELL FATE; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; DAUGHTER CELL; GENE LOCATION; GENE REPRESSION; GENETIC ASSOCIATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION; TRANSLATIONAL REPRESSION;

BINDING SITES; GENE EXPRESSION REGULATION, FUNGAL; NUCLEAR PROTEINS; PROTEIN BIOSYNTHESIS; REPRESSOR PROTEINS; RIBONUCLEOPROTEINS; RNA, MESSENGER; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84905570249     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku597     Document Type: Article

References (35)

1. Martin, K.C. and Ephrussi, A. (2009) mRNA localization: gene expression in the spatial dimension. Cell, 136, 719-730.
2. Shahbabian, K. and Chartrand, P. (2012) Control of cytoplasmic mRNA localization. Cell Mol. Life Sci., 69, 535-552.
3. Shepard, K.A., Gerber, A.P., Jambhekar, A., Takizawa, P.A., Brown, P.O., Herschlag, D., DeRisi, J.L. and Vale, R.D. (2003) Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis. Proc. Natl Acad. Sci. U.S.A., 100, 11429-11434.
4. Long, R.M., Singer, R.H., Meng, X., Gonzalez, I., Nasmyth, K. and Jansen, R.P. (1997) Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. Science, 277, 383-387.
5. Shen, Z., St-Denis, A. and Chartrand, P. (2010) Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud. Genes Dev., 24, 1914-1926.
6. Muller, M., Heym, R.G., Mayer, A., Kramer, K., Schmid, M., Cramer, P., Urlaub, H., Jansen, R.P. and Niessing, D. (2011) A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biol., 9, e1000611.
7. Takizawa, P.A. and Vale, R.D. (2000) The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. Proc. Natl Acad. Sci. U.S.A., 97, 5273-5278.
8. Gu, W., Deng, Y., Zenklusen, D. and Singer, R.H. (2004) A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes Dev., 18, 1452-1465.
9. Deng, Y., Singer, R.H. and Gu, W. (2008) Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation. Genes Dev., 22, 1037-1050.
10. Long, R.M., Gu, W., Meng, X., Gonsalvez, G., Singer, R.H. and Chartrand, P. (2001) An exclusively nuclear RNA-binding protein affects asymmetric localization of ASH1 mRNA and Ash1p in yeast. J. Cell Biol., 153, 307-318.
11. Komili, S., Farny, N.G., Roth, F.P. and Silver, P.A. (2007) Functional specificity among ribosomal proteins regulates gene expression. Cell, 131, 557-571.
12. Du, T.G., Jellbauer, S., Muller, M., Schmid, M., Niessing, D. and Jansen, R.P. (2008) Nuclear transit of the RNA-binding protein She2 is required for translational control of localized ASH1 mRNA. EMBO Rep., 9, 781-787.
13. Shen, Z., Paquin, N., Forget, A. and Chartrand, P. (2009) Nuclear shuttling of She2p couples ASH1 mRNA localization to its translational repression by recruiting Loc1p and Puf6p. Mol. Biol. Cell, 20, 2265-2275.
14. Lindstrom, D.L., Squazzo, S.L., Muster, N., Burckin, T.A., Wachter, K.C., Emigh, C.A., McCleery, J.A., Yates, J.R. 3rd and Hartzog, G.A. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol. Cell Biol., 23, 1368-1378.
15. Longtine, M.S., McKenzie, A. 3rd, Demarini, D.J., Shah, N.G., Wach, A., Brachat, A., Philippsen, P. and Pringle, J.R. (1998) Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast, 14, 953-961.
16. Bataille, A.R., Jeronimo, C., Jacques, P.E., Laramee, L., Fortin, M.E., Forest, A., Bergeron, M., Hanes, S.D. and Robert, F. (2012) A universal RNA polymerase II CTD cycle is orchestrated by complex interplays between kinase, phosphatase, and isomerase enzymes along genes. Mol. Cell, 45, 158-170.
17. Boyer, L.A., Lee, T.I., Cole, M.F., Johnstone, S.E., Levine, S.S., Zucker, J.P., Guenther, M.G., Kumar, R.M., Murray, H.L., Jenner, R.G. et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell, 122, 947-956.
18. Olivier, C., Poirier, G., Gendron, P., Boisgontier, A., Major, F. and Chartrand, P. (2005) Identification of a conserved RNA motif essential for She2p recognition and mRNA localization to the yeast bud. Mol. Cell Biol., 25, 4752-4766.
19. Niessing, D., Huttelmaier, S., Zenklusen, D., Singer, R.H. and Burley, S.K. (2004) She2p is a novel RNA binding protein with a basic helical hairpin motif. Cell, 119, 491-502.
20. Ghaemmaghami, S., Huh, W.K., Bower, K., Howson, R.W., Belle, A., Dephoure, N., O'Shea, E.K. and Weissman, J.S. (2003) Global analysis of protein expression in yeast. Nature, 425, 737-741.
21. Jansen, R.P., Dowzer, C., Michaelis, C., Galova, M. and Nasmyth, K. (1996) Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins. Cell, 84, 687-697.
22. Gerber, A.P., Herschlag, D. and Brown, P.O. (2004) Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol., 2, E79.
23. Besse, F. and Ephrussi, A. (2008) Translational control of localized mRNAs: restricting protein synthesis in space and time. Nat. Rev. Mol. Cell Biol., 9, 971-980.
24. Huttelmaier, S., Zenklusen, D., Lederer, M., Dictenberg, J., Lorenz, M., Meng, X., Bassell, G.J., Condeelis, J. and Singer, R.H. (2005) Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature, 438, 512-515.
25. Vazquez-Pianzola, P. and Suter, B. (2012) Conservation of the RNA transport machineries and their coupling to translation control across eukaryotes. Comp. Funct. Genomics, 2012, 287852.
26. Niedner, A., Müller, M., Moorthy, B.T., Jansen, R.-P. and Niessing, D. (2013) Role of Loc1p in assembly and reorganization of nuclear ASH1 messenger ribonucleoprotein particles in yeast. Proc. Natl Acad. Sci. U.S.A., 110, E5049-E5058.
27. Levin, D.E. (2011) Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway. Genetics, 189, 1145-1175.
28. Hasegawa, Y., Irie, K. and Gerber, A.P. (2008) Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA, 14, 2333-2347.
29. Wolf, J.J., Dowell, R.D., Mahony, S., Rabani, M., Gifford, D.K. and Fink, G.R. (2010) Feed-forward regulation of a cell fate determinant by an RNA-binding protein generates asymmetry in yeast. Genetics, 185, 513-522.
30. Ross, A.F., Oleynikov, Y., Kislauskis, E.H., Taneja, K.L. and Singer, R.H. (1997) Characterization of a beta-actin mRNA zipcode-binding protein. Mol. Cell Biol., 17, 2158-2165.
31. Oleynikov, Y. and Singer, R.H. (2003) Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization. Curr. Biol., 13, 199-207.
32. Pan, F., Huttelmaier, S., Singer, R.H. and Gu, W. (2007) ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Mol. Cell Biol., 27, 8340-8351.
33. Haimovich, G., Choder, M., Singer, R.H. and Trcek, T. (2013) The fate of the messenger is pre-determined: a new model for regulation of gene expression. Biochim. Biophys. Acta, 1829, 643-653.
34. Gietz, R.D. and Sugino, A. (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene, 74, 527-534.
35. Long, R.M., Gu, W., Lorimer, E., Singer, R.H. and Chartrand, P. (2000) She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA. EMBO J., 19, 6592-6601.