Mitochondrial STAT3 plays a major role in IgE-antigen-mediated mast cell exocytosis

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 2, 2014, Pages

  Erlich, Tal Hadad ^a   Yagil, Zohar ^a   Kay, Gillian ^a   Peretz, Alona ^a   Migalovich Sheikhet, Helena ^a   Tshori, Sagi ^b   Nechushtan, Hovav ^b   Levi Schaffer, Francesca ^a   Saada, Ann ^b   Razin, Ehud ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Allergy; cytokines; degranulation; mast cells; mitochondria; PIAS3; STAT3

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA N ACETYLHEXOSAMINIDASE; CASPASE 3; CYTOCHROME C OXIDASE; GRANZYME B; HISTAMINE; IMMUNOGLOBULIN E; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PIAS3 PROTEIN; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; STAT3 PROTEIN; SUCCINATE DEHYDROGENASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2,4 DINITROPHENOL; ANTIGEN; MAPK1 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; PIAS3 PROTEIN, MOUSE; PROTEIN INHIBITOR OF ACTIVATED STAT; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE; STATTIC; SULFOXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; EXOCYTOSIS; FEMALE; GLYCOLYSIS; HISTAMINE METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MAST CELL; MAST CELL DEGRANULATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; UMBILICAL CORD BLOOD; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; C3H MOUSE; DEGRANULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTIGENS; CELL DEGRANULATION; CELL LINE, TUMOR; CYCLIC S-OXIDES; DINITROPHENOLS; EXOCYTOSIS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOGLOBULIN E; MAST CELLS; MICE; MICE, INBRED C3H; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OXIDATIVE PHOSPHORYLATION; PROTEIN INHIBITORS OF ACTIVATED STAT; RATS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84905568336     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.12.1075     Document Type: Article

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