Structure of Kif14: An engaging molecular motor

Journal of Molecular Biology

Volumn 426, Issue 17, 2014, Pages 2993-2996

  Rice, Sarah ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KIF14 PROTEIN; KINESIN; MOLECULAR MOTOR; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; KINESIN 1; MAGNESIUM; MYOSIN; NUCLEOTIDE; SERINE;

CRYSTAL STRUCTURE; MICROTUBULE; MOLECULAR DYNAMICS; NOTE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; CYTOKINESIS; DEPOLYMERIZATION; ENZYME ACTIVITY; ENZYME CONFORMATION; HYDROGEN BOND; REVIEW;

ANIMALS; KINESIN; MICROTUBULES;

EID: 84905505616     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.06.008     Document Type: Note

References (26)

1. A. Blangy, H.A. Lane, P. d'Herin, M. Harper, M. Kress, and E.A. Nigg Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo Cell 83 1995 1159 1169
2. M.E. Tanenbaum, L. Macurek, N. Galjart, and R.H. Medema Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly EMBO J 27 2008 3235 3245
3. N. Gudimchuk, B. Vitre, Y. Kim, A. Kiyatkin, D.W. Cleveland, and F.I. Ataullakhanov et al. Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips Nat Cell Biol 15 2013 1079 1088
4. U. Gruneberg, R. Neef, X. Li, E.H. Chan, R.B. Chalamalasetty, and E.A. Nigg et al. KIF14 and citron kinase act together to promote efficient cytokinesis J Cell Biol 172 2006 363 372
5. T.L. Blasius, D. Cai, G.T. Jih, C.P. Toret, and K.J. Verhey Two binding partners cooperate to activate the molecular motor Kinesin-1 J Cell Biol 176 2007 11 17
6. J.W. Hammond, D. Cai, T.L. Blasius, Z. Li, Y. Jiang, and G.T. Jih et al. Mammalian Kinesin-3 motors are dimeric in vivo and move by processive motility upon release of autoinhibition PLoS Biol 7 2009 e72
7. J.W. Hammond, T.L. Blasius, V. Soppina, D. Cai, and K.J. Verhey Autoinhibition of the kinesin-2 motor KIF17 via dual intramolecular mechanisms J Cell Biol 189 2010 1013 1025
8. M. Imanishi, N.F. Endres, A. Gennerich, and R.D. Vale Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3 J Cell Biol 174 2006 931 937
9. K.E. Sawin, and T.J. Mitchison Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle Proc Natl Acad Sci USA 92 1995 4289 4293
10. M.K. Mattson-Hoss, Y. Niitani, E.A. Gordon, Y. Jun, L. Bardwell, and M. Tomishige et al. CK2 activates kinesin via induction of a conformational change Proc Natl Acad Sci USA 111 2014 7000 7005
11. O. Rath, and F. Kozielski Kinesins and cancer Nat Rev Cancer 12 2012 527 539
12. J. Turner, R. Anderson, J. Guo, C. Beraud, R. Fletterick, and R. Sakowicz Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker J Biol Chem 276 2001 25496 25502
13. C.V. Sindelar A seesaw model for intermolecular gating in the kinesin motor protein Biophys Rev 3 2011 85 100
14. P.D. Coureux, A.L. Wells, J. Menetrey, C.M. Yengo, C.A. Morris, and H.L. Sweeney et al. A structural state of the myosin V motor without bound nucleotide Nature 425 2003 419 423
15. T.F. Reubold, S. Eschenburg, A. Becker, F.J. Kull, and D.J. Manstein A structural model for actin-induced nucleotide release in myosin Nat Struct Biol 10 2003 826 830
16. F.J. Kull, and S.A. Endow Force generation by kinesin and myosin cytoskeletal motor proteins J Cell Sci 126 2013 9 19
17. C.V. Sindelar, and K.H. Downing An atomic-level mechanism for activation of the kinesin molecular motors Proc Natl Acad Sci USA 107 2010 4111 4116
18. A. Goulet, W.M. Behnke-Parks, C.V. Sindelar, J. Major, S.S. Rosenfeld, and C.A. Moores The structural basis of force generation by the mitotic motor kinesin-5 J Biol Chem 287 2012 44654 44666
19. B. Gigant, W. Wang, B. Dreier, Q. Jiang, L. Pecqueur, and A. Pluckthun et al. Structure of a kinesin-tubulin complex and implications for kinesin motility Nat Struct Mol Biol 20 2013 1001 1007
20. A. Krukau, V. Knecht, and R. Lipowsky Allosteric control of kinesin's motor domain by tubulin: a molecular dynamics study Phys Chem Chem Phys 16 2014 6189 6198
21. Y.Z. Ma, and E.W. Taylor Kinetic mechanism of kinesin motor domain Biochemistry 34 1995 13233 13241
22. R. Nitta, Y. Okada, and N. Hirokawa Structural model for strain-dependent microtubule activation of Mg-ADP release from kinesin Nat Struct Mol Biol 15 2008 1067 1075
23. M. Kikkawa, and N. Hirokawa High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations EMBO J 25 2006 4187 4194
24. B. Takacs, E. O'Neall-Hennessey, C. Hetenyi, J. Kardos, A.G. Szent-Gyorgyi, and M. Kovacs Myosin cleft closure determines the energetics of the actomyosin interaction FASEB J 25 2011 111 121
25. T.C. Krzysiak, M. Grabe, and S.P. Gilbert Getting in sync with dimeric Eg5. Initiation and regulation of the processive run J Biol Chem 283 2008 2078 2087
26. J.S. Waitzman, A.G. Larson, J.C. Cochran, N. Naber, R. Cooke, and F. Jon Kull et al. The loop 5 element structurally and kinetically coordinates dimers of the human kinesin-5, Eg5 Biophys J 101 2011 2760 2769