Hyaluronic acid-based nanogel-drug conjugates with enhanced anticancer activity designed for the targeting of cd44-positive and drug-resistant tumors

Bioconjugate Chemistry

Volumn 24, Issue 4, 2013, Pages 658-668

  Wei, Xin ^a   Senanayake, Thulani H ^a   Warren, Galya ^a   Vinogradov, Serguei V ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; CYTOTOXICITY; DISEASES; DRUG DELIVERY; DRUG PRODUCTS; HYALURONIC ACID; MOLECULAR BIOLOGY; ORGANIC ACIDS; STEM CELLS; TUMORS;

ANTICANCER ACTIVITIES; CANCER CELLS; CANCER STEM CELLS; CELLULARS; DRUG-CONJUGATES; ELEVATED LEVEL; ETOPOSIDE; NANOGELS; POORLY SOLUBLE DRUGS; SALINOMYCIN;

NANOSTRUCTURED MATERIALS;

CHOLESTEROL; CURCUMIN; ETOPOSIDE; FLOXURIDINE; HERMES ANTIGEN; HYALURONIC ACID; NANOPARTICLE; SALINOMYCIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CANCER RESISTANCE; CANCER STEM CELL; CELL MEMBRANE; CELL SHAPE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG RELEASE; DRUG SOLUBILITY; DRUG SYNTHESIS; DRUG TARGETING; ENDOCYTOSIS; GEL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHOBICITY; NANOGEL; PANCREAS ADENOCARCINOMA; PARTICLE SIZE; PROTEIN PROTEIN INTERACTION; PROTEIN UNFOLDING;

EID: 84876484728     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc300632w     Document Type: Article

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