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Volumn 19, Issue 3, 2014, Pages 534-544

Effect of molecular weight of chitosan on antimicrobial properties and tissue compatibility of chitosan-impregnated bacterial cellulose films

Author keywords

bacterial cellulose; chitosan; fibroblasts; keratinocytes; release

Indexed keywords

ASPERGILLUS; BACTERIA; CELL CULTURE; CELLULOSE; CELLULOSE FILMS; CHITOSAN; COMPOSITE FILMS; ESCHERICHIA COLI; FIBROBLASTS; MOLECULAR WEIGHT;

EID: 84905441335     PISSN: 12268372     EISSN: 19763816     Source Type: Journal    
DOI: 10.1007/s12257-014-0081-x     Document Type: Article
Times cited : (72)

References (50)
  • 2
    • 0031599129 scopus 로고    scopus 로고
    • Production and application of microbial cellulose
    • PII S0141391097001973
    • Jonas, R. and L. F. Farah (1998) Production and application of microbial cellulose. Polym. Degrade. Stabil. 59: 101-106. (Pubitemid 128389698)
    • (1998) Polymer Degradation and Stability , vol.59 , Issue.1-3 , pp. 101-106
    • Jonas, R.1    Farah, L.F.2
  • 3
    • 12144251133 scopus 로고    scopus 로고
    • Towards electronic paper displays made from microbial cellulose
    • DOI 10.1007/s00253-004-1756-6
    • Shah, J. and R. M. Brown Jr. (2005) Towards electronic paper displays made from microbial cellulose. Appl. Microbiol. Biotechnol. 66: 352-355. (Pubitemid 40110138)
    • (2005) Applied Microbiology and Biotechnology , vol.66 , Issue.4 , pp. 352-355
    • Shah, J.1    Brown Jr., R.M.2
  • 4
    • 13444258720 scopus 로고    scopus 로고
    • Multifunctional bacterial cellulose/chitosan composite materials for medical applications
    • Ciechanska, D. (2004) Multifunctional bacterial cellulose/chitosan composite materials for medical applications. Fibres Text. East. Eur. 12: 69-72.
    • (2004) Fibres Text. East. Eur. , vol.12 , pp. 69-72
    • Ciechanska, D.1
  • 6
    • 24644517577 scopus 로고    scopus 로고
    • Microbial cellulose - The natural power to heal wounds
    • DOI 10.1016/j.biomaterials.2005.07.035, PII S0142961205007040
    • Czaja, W., A. Krystynowicz, and S. Bielecki (2006) Microbial cellulose-the natural power to heal wounds. Biomate. 27: 145-151. (Pubitemid 41282793)
    • (2006) Biomaterials , vol.27 , Issue.2 , pp. 145-151
    • Czaja, W.1    Krystynowicz, A.2    Bielecki, S.3    Brown Jr., R.M.4
  • 7
    • 33846410643 scopus 로고    scopus 로고
    • The future prospects of microbial cellulose in biomedical applications
    • DOI 10.1021/bm060620d
    • Czaja, W., D. J. Young, M. Kawechi, and R. M. Brown Jr. (2007) The future prospects of Microbial cellulose in biomedical applications. Biomacromol. 8: 1-12. (Pubitemid 46140466)
    • (2007) Biomacromolecules , vol.8 , Issue.1 , pp. 1-12
    • Czaja, W.K.1    Young, D.J.2    Kawecki, M.3    Brown Jr., R.M.4
  • 8
    • 0035505468 scopus 로고    scopus 로고
    • Bacterial synthesized cellulose - Artificial blood vessels for microsurgery
    • DOI 10.1016/S0079-6700(01)00021-1, PII S0079670001000211
    • Klemm, D., D. Schumann, U. Udhardt, and S. Marsch (2001) Bacterial synthesized cellulose artificial blood vessels for microsurgery. Prog. Polym. Sci. 26: 1561-1603. (Pubitemid 33090643)
    • (2001) Progress in Polymer Science (Oxford) , vol.26 , Issue.9 , pp. 1561-1603
    • Klemm, D.1    Schumann, D.2    Udhardt, U.3    Marsch, S.4
  • 9
    • 77952875502 scopus 로고    scopus 로고
    • Poly(vinyl alcohol)-bacterial cellulose nanocomposite
    • US Patent 2,005,037,082
    • Wan, W. K. and L. E. Millon (2005) Poly(vinyl alcohol)-bacterial cellulose nanocomposite. US Patent 2,005,037,082.
    • (2005)
    • Wan, W.K.1    Millon, L.E.2
  • 10
    • 33746253257 scopus 로고    scopus 로고
    • Surface modification of polyester to produce a bacterial cellulose-based vascular prosthetic device
    • DOI 10.1016/j.apsusc.2005.09.064, PII S0169433205014625
    • Charpentier, P. A., A. Maguire, and W. Wan (2006) Surface modification of polyester to produce a bacterial cellulose-based vascular prosthetic device. Appl. Surf. Sci. 252: 6360-6367. (Pubitemid 44093086)
    • (2006) Applied Surface Science , vol.252 , Issue.18 , pp. 6360-6367
    • Charpentier, P.A.1    Maguire, A.2    Wan, W.-k.3
  • 11
    • 42949147002 scopus 로고    scopus 로고
    • Preparation and characterization of a novel COL/BC composite for potential tissue engineering scaffolds
    • DOI 10.1016/j.matchemphys.2008.01.040, PII S0254058408000345
    • Luo, H., G. Xiong, Y. Huang, F. He, Y. Wang, and Y. Wan (2008) Preparation and characterization of a novel COL/BC composite for potential tissue engineering scaffolds. Mater. Chem. Phys. 110: 193-196. (Pubitemid 351609152)
    • (2008) Materials Chemistry and Physics , vol.110 , Issue.2-3 , pp. 193-196
    • Luo, H.1    Xiong, G.2    Huang, Y.3    He, F.4    Wang, Y.5    Wan, Y.6
  • 12
    • 36749086364 scopus 로고    scopus 로고
    • Bacterial cellulose and its nanocomposites for biomedical applications
    • K. Oksman and M. Sain (eds.). American Chemical Society, Washington D. C., USA
    • W. K. Wan, J. L. Hutter, L. Milton, and G. Guhados (2006) Bacterial cellulose and its nanocomposites for biomedical applications. pp. 221-241. In: K. Oksman and M. Sain (eds.). Cellulose Nanocomposites: ACS Symposium Series. American Chemical Society, Washington D. C., USA.
    • (2006) Cellulose Nanocomposites: ACS Symposium Series , pp. 221-241
    • Wan, W.K.1    Hutter, J.L.2    Milton, L.3    Guhados, G.4
  • 13
    • 77953568787 scopus 로고    scopus 로고
    • In vitro cytotoxicity of bacterial cellulose scaffolds used for tissue-engineered bone
    • Chen, Y. M., T. Xi, Y. Zheng, T. Guo, J. Hou, Y. Wan, and C. Gao (2009) In vitro cytotoxicity of bacterial cellulose scaffolds used for tissue-engineered bone. J. Bioact. Compat. Pol. 24: 137-145.
    • (2009) J. Bioact. Compat. Pol. , vol.24 , pp. 137-145
    • Chen, Y.M.1    Xi, T.2    Zheng, Y.3    Guo, T.4    Hou, J.5    Wan, Y.6    Gao, C.7
  • 14
    • 28744448243 scopus 로고    scopus 로고
    • Mechanical properties of bacterial cellulose and interactions with smooth muscle cells
    • DOI 10.1016/j.biomaterials.2005.10.026, PII S0142961205009993
    • Backdahl, H., G. Helenius, A. Bodin, U. Nannmark, B. R. Johansson, B. Risberg, and P. Gatenholm (2006) Mechanical properties of bacterial cellulose and interactions with smooth muscle cells. Biomat.27: 2141-2149. (Pubitemid 41759508)
    • (2006) Biomaterials , vol.27 , Issue.9 , pp. 2141-2149
    • Backdahl, H.1    Helenius, G.2    Bodin, A.3    Nannmark, U.4    Johansson, B.R.5    Risberg, B.6    Gatenholm, P.7
  • 15
    • 3242655507 scopus 로고    scopus 로고
    • Bacterial cellulose as a potential scaffold for tissue engineering of cartilage
    • DOI 10.1016/j.biomaterials.2004.02.049, PII S014296120400198X
    • Svensson, A., E. Nicklasson, T. Harrah, B. Panilaiis, D. L. Kaplan, M. Brittberg, and P. Gatenholm (2005) Bacterial cellulose as a potential scaffold for tissue engineering of cartilage. Biomat. 26: 419-431. (Pubitemid 38951109)
    • (2005) Biomaterials , vol.26 , Issue.4 , pp. 419-431
    • Svensson, A.1    Nicklasson, E.2    Harrah, T.3    Panilaitis, B.4    Kaplan, D.L.5    Brittberg, M.6    Gatenholm, P.7
  • 16
    • 0009365216 scopus 로고    scopus 로고
    • A review of chitin and chitosan applications
    • Majeti, N. V. and R. Kumar (2000) A review of chitin and chitosan applications. React. Funct. Polymers 46: 1-27.
    • (2000) React. Funct. Polymers , vol.46 , pp. 1-27
    • Majeti, N.V.1    Kumar, R.2
  • 17
    • 78149470032 scopus 로고    scopus 로고
    • Antimicrobial properties of chitosan and mode of action: A state of the art review
    • Kong, M., X. G. Chen, K. Xing, and H. J. Park (2010) Antimicrobial properties of chitosan and mode of action: A state of the art review. Int. J. Food Microbiol. 144: 51-63.
    • (2010) Int. J. Food Microbiol. , vol.144 , pp. 51-63
    • Kong, M.1    Chen, X.G.2    Xing, K.3    Park, H.J.4
  • 20
    • 33745111194 scopus 로고    scopus 로고
    • Effect of MW and concentration of chitosan on antibacterial activity of Escherichia coli
    • DOI 10.1016/j.carbpol.2005.10.028, PII S0144861705005291
    • Liu, N., X. G. Chen, H. J. Park, C. G. Liu, C. S. Liu, and X. H. Meng (2006) Effect of MW and concentration of chitosan on antibacterial activity of Escherichia coli. Carbohyd. Polym. 64: 60-65. (Pubitemid 43884936)
    • (2006) Carbohydrate Polymers , vol.64 , Issue.1 , pp. 60-65
    • Liu, N.1    Chen, X.-G.2    Park, H.-J.3    Liu, C.-G.4    Liu, C.-S.5    Meng, X.-H.6    Yu, L.-J.7
  • 21
    • 84870186927 scopus 로고    scopus 로고
    • Effect of different molecular weights of chitosan on preparation and characterization of insulin loaded nanoparticles by ion gelation method
    • Kouchak, M., M. Avadi, M. Abbaspour, A. Jahangiri, and S. K. Boldaji (2012) Effect of different molecular weights of chitosan on preparation and characterization of insulin loaded nanoparticles by ion gelation method. Int. J. Drug Dev. Res. 4: 271-277.
    • (2012) Int. J. Drug Dev. Res. , vol.4 , pp. 271-277
    • Kouchak, M.1    Avadi, M.2    Abbaspour, M.3    Jahangiri, A.4    Boldaji, S.K.5
  • 22
    • 59249098389 scopus 로고    scopus 로고
    • Chitin and chitosan for the repair of wounded skin, nerve, cartilage and bone
    • Muzzarelli, R. A. A. (2009) Chitin and chitosan for the repair of wounded skin, nerve, cartilage and bone. Carbohyd. Polym. 76: 167-182.
    • (2009) Carbohyd. Polym. , vol.76 , pp. 167-182
    • Muzzarelli, R.A.A.1
  • 23
    • 0009365216 scopus 로고    scopus 로고
    • A review of chitin and chitosan applications
    • Kumar, R. M. (2000) A review of chitin and chitosan applications. React. Funct. Polym. 46: 1-27.
    • (2000) React. Funct. Polym. , vol.46 , pp. 1-27
    • Kumar, R.M.1
  • 24
    • 84872780702 scopus 로고    scopus 로고
    • Polyox and carrageenan based composite film dressing containing anti-microbial and anti-inflammatory drugs for effective wound healing
    • Boateng, J. S., H. V. Pawar, and J. Tetteh (2013) Polyox and carrageenan based composite film dressing containing anti-microbial and anti-inflammatory drugs for effective wound healing. Int. J. Pharm. 441: 181-191.
    • (2013) Int. J. Pharm. , vol.441 , pp. 181-191
    • Boateng, J.S.1    Pawar, H.V.2    Tetteh, J.3
  • 25
    • 84866502566 scopus 로고    scopus 로고
    • Preparation and characterization of novel wound healing film dressings loaded with streptomycin and diclofenac
    • Pawar, H. V., J. Tetteh, and J. S. Boateng (2013) Preparation and characterization of novel wound healing film dressings loaded with streptomycin and diclofenac. Colloids Surf. B.102: 102-110.
    • (2013) Colloids Surf. B. , vol.102 , pp. 102-110
    • Pawar, H.V.1    Tetteh, J.2    Boateng, J.S.3
  • 26
    • 49149096105 scopus 로고    scopus 로고
    • Biosynthesis and characterization of bacteria cellulose-chitosan film
    • Phisalaphong, M. and N. Jatupaiboon (2008) Biosynthesis and characterization of bacteria cellulose-chitosan film. Carbohyd. Polym. 74: 482-488.
    • (2008) Carbohyd. Polym. , vol.74 , pp. 482-488
    • Phisalaphong, M.1    Jatupaiboon, N.2
  • 27
    • 84988505041 scopus 로고    scopus 로고
    • Antimicrobial activity of chitin, chitosan, and their oligosaccharides
    • S.-K. Kim (ed.). CRC Press, NW, USA
    • Dutta, J. and P. K. Dutta (2011) Antimicrobial activity of chitin, chitosan, and their oligosaccharides. pp. 195-214. In: S.-K. Kim (ed.). Chitin, Chitosan, Oligosaccharides and Their Derivatives. CRC Press, NW, USA.
    • (2011) Chitin, Chitosan, Oligosaccharides and Their Derivatives , pp. 195-214
    • Dutta, J.1    Dutta, P.K.2
  • 28
    • 84880369246 scopus 로고    scopus 로고
    • Physicochemical properties and antioxidant activity of chitosan from the blow fly Chrysomya megacephala larve
    • Song, C., H. Yu, M. Zhang, Y. Yang, and G. Zhang (2013) Physicochemical properties and antioxidant activity of chitosan from the blow fly Chrysomya megacephala larve. Int. J. Biol. Macromol. 60: 347-354.
    • (2013) Int. J. Biol. Macromol. , vol.60 , pp. 347-354
    • Song, C.1    Yu, H.2    Zhang, M.3    Yang, Y.4    Zhang, G.5
  • 29
    • 77955119164 scopus 로고    scopus 로고
    • Biocompatibility and growth of human keratinocytes and fibroblasts on biosynthesized cellulose-chitosan film
    • Kingkaew, J., N. Jatupaiboon, N. Sanchavanakit, P. Pavasant, and M. Phisalaphong (2010) Biocompatibility and growth of human keratinocytes and fibroblasts on biosynthesized cellulose-chitosan film. J. Biomat. Sci. 21: 1009-1021.
    • (2010) J. Biomat. Sci. , vol.21 , pp. 1009-1021
    • Kingkaew, J.1    Jatupaiboon, N.2    Sanchavanakit, N.3    Pavasant, P.4    Phisalaphong, M.5
  • 30
    • 84883217138 scopus 로고    scopus 로고
    • Comparison of new dynamic accumulation method for measuring oxygen transmission rate of packing against the steady-state method described by ASTM D3985
    • Abdellatief, A. and B. A. Welt (2013) Comparison of new dynamic accumulation method for measuring oxygen transmission rate of packing against the steady-state method described by ASTM D3985. Packag. Technol. Sci. 26: 281-288.
    • (2013) Packag. Technol. Sci. , vol.26 , pp. 281-288
    • Abdellatief, A.1    Welt, B.A.2
  • 31
    • 36749061317 scopus 로고    scopus 로고
    • Electrospun cellulose acetate fiber mats containing curcumin and release characteristic of the herbal substance
    • Suwantong, O., P. Opanasopit, U. Ruktanonchai, and P. Supaphol (2008) Electrospun cellulose acetate fiber mats containing curcumin and release characteristic of the herbal substance. Polymer 42: 7546-7557.
    • (2008) Polymer , vol.42 , pp. 7546-7557
    • Suwantong, O.1    Opanasopit, P.2    Ruktanonchai, U.3    Supaphol, P.4
  • 32
    • 1142273420 scopus 로고    scopus 로고
    • Use of the ninhydrin assay to measure the release of chitosan from oral solid dosage forms
    • DOI 10.1016/j.ijpharm.2003.11.023
    • Leane, M. M., R. Nankervis, A. Smith, and L. Illum (2004) Use of the ninhydrin assay to measure the release of chitosan from oral solid dosage forms. Int. J. Pharm. 271: 241-249. (Pubitemid 38210102)
    • (2004) International Journal of Pharmaceutics , vol.271 , Issue.1-2 , pp. 241-249
    • Leane, M.M.1    Nankervis, R.2    Smith, A.3    Illum, L.4
  • 33
    • 84865511794 scopus 로고    scopus 로고
    • Fractionation of chitosan by supercritical carbon dioxide/acetic acid aqueous solution
    • Lee, W. K., M. L. Tsai, and Y. T. Shien (2012) Fractionation of chitosan by supercritical carbon dioxide/acetic acid aqueous solution. J. Supercrit. Fluid. 71: 86-91.
    • (2012) J. Supercrit. Fluid. , vol.71 , pp. 86-91
    • Lee, W.K.1    Tsai, M.L.2    Shien, Y.T.3
  • 34
    • 79959763877 scopus 로고    scopus 로고
    • Preparation and characterization of a Bacterial cellulose/Chitosan composite for potential biomedical application
    • Kim, J., Z. Cai, H. S. Lee, G. S. Choi, D. H. Lee, and C. Jo (2011) Preparation and characterization of a Bacterial cellulose/Chitosan composite for potential biomedical application. J. Polym. Res. 18: 739-744.
    • (2011) J. Polym. Res. , vol.18 , pp. 739-744
    • Kim, J.1    Cai, Z.2    Lee, H.S.3    Choi, G.S.4    Lee, D.H.5    Jo, C.6
  • 35
    • 79961029323 scopus 로고    scopus 로고
    • Effect of chitosan penetration on physic-chemical and mechanical properties of bacterial cellulose
    • UI-Islam, M., N. Shah, J. H. Ha, and J. K. Park (2011) Effect of chitosan penetration on physic-chemical and mechanical properties of bacterial cellulose. Kor. J. Chem. Eng. 28: 1736-1743.
    • (2011) Kor. J. Chem. Eng. , vol.28 , pp. 1736-1743
    • Ui-Islam, M.1    Shah, N.2    Ha, J.H.3    Park, J.K.4
  • 36
    • 84881528437 scopus 로고    scopus 로고
    • An intergrated buccal delivery system combining chitosan films impregnated with peptide loaded PEG-b-PLA nanoparticles
    • Giovino, C., I. Ayensu, J. Tetteh, and J. S. Boateng (2013) An intergrated buccal delivery system combining chitosan films impregnated with peptide loaded PEG-b-PLA nanoparticles. Colloid Surface B. 112: 9-15.
    • (2013) Colloid Surface B. , vol.112 , pp. 9-15
    • Giovino, C.1    Ayensu, I.2    Tetteh, J.3    Boateng, J.S.4
  • 38
    • 84855188370 scopus 로고    scopus 로고
    • Development and physic-mechanical characterization of lyophilized chitosan wafers as potential protein drug delivery systems via the buccal mucosa
    • Ayensu, I., J. C. Mitchell, and J. S. Boateng (2012) Development and physic-mechanical characterization of lyophilized chitosan wafers as potential protein drug delivery systems via the buccal mucosa. Colloid Surface B. 91: 258-265.
    • (2012) Colloid Surface B. , vol.91 , pp. 258-265
    • Ayensu, I.1    Mitchell, J.C.2    Boateng, J.S.3
  • 39
    • 77952880781 scopus 로고    scopus 로고
    • Bacterial cellulose/poly (ethylene glycol) composite
    • Cai, Z. and J. Kim (2010) Bacterial cellulose/poly (ethylene glycol) composite. Cellulose. 17: 83-91.
    • (2010) Cellulose. , vol.17 , pp. 83-91
    • Cai, Z.1    Kim, J.2
  • 41
    • 0030209192 scopus 로고    scopus 로고
    • Application of benzyl hyaluronate membranes as potential wound dressings: Evaluation of water vapour and gas permeabilities
    • DOI 10.1016/0142-9612(95)00324-X
    • Cardona, L., Y. Sanzgiri, L. Benedetti, V. Stella, and E. Topp (1996) Application of benzyl hyaluronate membranes as potential wound dressings: Evaluation of water vapour and gas permeabilities. Biomat. 17: 1639-1643. (Pubitemid 26289753)
    • (1996) Biomaterials , vol.17 , Issue.16 , pp. 1639-1643
    • Ruiz-Cardona, L.1    Sanzgiri, Y.D.2    Benedetti, L.M.3    Stella, V.J.4    Topp, E.M.5
  • 42
    • 84905466890 scopus 로고    scopus 로고
    • Two part wound dressing
    • US Patent 0,051,688 A1
    • Lowe, R. D. (2008) Two part wound dressing. US Patent 0,051,688 A1.
    • (2008)
    • Lowe, R.D.1
  • 43
    • 0037170816 scopus 로고    scopus 로고
    • Antibacterial activity of chitosans and chitosan oligomers with different molecular weights
    • DOI 10.1016/S0168-1605(01)00717-6, PII S0168160501007176
    • No, H. K., N. Y. Park, S. H. Lee, and S. P. Meyers (2002) Antibacterial activity of chitosans and chitosan oligomers with different molecular weights. Int. J. Food Microbiol. 74: 65-72. (Pubitemid 34203704)
    • (2002) International Journal of Food Microbiology , vol.74 , Issue.1-2 , pp. 65-72
    • No, H.K.1    Young, P.N.2    Ho, L.S.3    Meyers, S.P.4
  • 45
    • 0345257221 scopus 로고    scopus 로고
    • Chitosan as antimicrobial agent: Applications and mode of action
    • DOI 10.1021/bm034130m
    • Rabea, E. I., M. El Badawy, C. V. Stevens, G. Smagghe, and W. Steurbaut (2003) Chitosan as antimicrobial agent: Applications and mode of action. Biomacromol. 4: 1457-1465. (Pubitemid 37455555)
    • (2003) Biomacromolecules , vol.4 , Issue.6 , pp. 1457-1465
    • Rabea, E.I.1    Badawy, M.E.-T.2    Stevens, C.V.3    Smagghe, G.4    Steurbaut, W.5
  • 47
    • 84875799674 scopus 로고    scopus 로고
    • Bacterial cellulose and bacterial cellulose-chitosan membranes for wound dressing applications
    • Lin, W. C., C. C. Lien, H. J. Yeh, C. M. Yu, and S. H. Hsu (2013) Bacterial cellulose and bacterial cellulose-chitosan membranes for wound dressing applications. Carbohyd. Polym. 94: 603-611.
    • (2013) Carbohyd. Polym. , vol.94 , pp. 603-611
    • Lin, W.C.1    Lien, C.C.2    Yeh, H.J.3    Yu, C.M.4    Hsu, S.H.5
  • 48
    • 0035889837 scopus 로고    scopus 로고
    • The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro
    • DOI 10.1016/S0142-9612(01)00042-4, PII S0142961201000424
    • Howling, G. I., P. W. Dettmar, P. A. Goddard, F. C. Hampson, M. Dornish, and E. J. Wood (2001) The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro. Biomat. 22:2959-2966. (Pubitemid 32768703)
    • (2001) Biomaterials , vol.22 , Issue.22 , pp. 2959-2966
    • Howling, G.I.1    Dettmar, P.W.2    Goddard, P.A.3    Hampson, F.C.4    Dornish, M.5    Wood, E.J.6
  • 49
    • 84887163208 scopus 로고    scopus 로고
    • Physical, antioxidant and antimicrobial properties of chitosan-cinnamon leaf oil films as affected by oleic acid
    • Perdones, T., M. Vargas, L. Atarés, and A. Chiralt (2014) Physical, antioxidant and antimicrobial properties of chitosan-cinnamon leaf oil films as affected by oleic acid. Food Hydrocolloid. 36: 256-264.
    • (2014) Food Hydrocolloid. , vol.36 , pp. 256-264
    • Perdones, T.1    Vargas, M.2    Atarés, L.3    Chiralt, A.4


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