Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus

Journal of Biological Chemistry

Volumn 289, Issue 31, 2014, Pages 21276-21288

  Liefhebber, Jolanda M P ^a   Hague, Charlotte V ^a   Zhang, Qifeng ^b   Wakelam, Michael J O ^b   McLauchlan, John ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DROPS; ESTERIFICATION; ESTERS; LIPIDS; VIRUSES;

ACYL-COA:CHOLESTEROL ACYLTRANSFERASE; ANTIVIRAL PROPERTIES; CELLULAR METABOLIC PROCESS; CHOLESTEROL ESTERS; CHRONIC HEPATITIS C; HIGH RESOLUTION DATA; LONG-CHAIN ACYL-COA; THERAPEUTIC INTERVENTION;

ASSEMBLY;

CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; CORE PROTEIN; ENZYME INHIBITOR; FAT DROPLET; LONG CHAIN FATTY ACID COENZYME A LIGASE; TRIACSIN C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; YIC C8 434 COMPOUND; VIRUS RNA;

ARTICLE; ELECTROPORATION; HEPATITIS C; HEPATITIS C VIRUS; IMMUNOFLUORESCENCE; IN VITRO STUDY; LIPID ANALYSIS; LIPID COMPOSITION; MASS SPECTROMETRY; MORPHOLOGY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN STABILITY; VIRION; VIRUS ASSEMBLY; VIRUS NUCLEOCAPSID; VIRUS PARTICLE; WESTERN BLOTTING; BIOSYNTHESIS; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HEPACIVIRUS; HUMAN; PHYSIOLOGY;

CELL LINE; CHOLESTEROL ESTERS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HEPACIVIRUS; HUMANS; RNA, VIRAL; TRIGLYCERIDES; VIRION; VIRUS ASSEMBLY;

EID: 84905404679     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.582999     Document Type: Article

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