Method development for the detection of human myostatin by high-resolution and targeted mass spectrometry

Journal of Proteome Research

Volumn 13, Issue 8, 2014, Pages 3802-3809

  Peiris, Hassendrini Nileishika ^a   Ashman, Keith ^a   Vaswani, Kanchan ^a   Kvaskoff, David ^a   Rice, Gregory Edward ^a   Mitchell, Murray David ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

GDF 8; mass spectrometry; Myostatin

Indexed keywords

MYOSTATIN; PEPTIDE FRAGMENT;

AMINO ACID SEQUENCE; ARTICLE; BIOLOGICAL MONITORING; CONTROLLED STUDY; HUMAN; LIMIT OF DETECTION; LIMIT OF QUANTITATION; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; TANDEM MASS SPECTROMETRY;

EID: 84905394555     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5004642     Document Type: Article

References (37)

1. McPherron, A. C.; Lawler, A. M.; Lee, S. J. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member Nature 1997, 387, 83-90
2. Lee, S. J. Regulation of muscle mass by myostatin Annu. Rev. Cell Dev. Biol. 2004, 20, 61-86
3. Schuelke, M.; Wagner, K. R.; Stolz, L. E.; Hübner, C.; Riebel, T.; Kömen, W.; Braun, T.; Tobin, J. F.; Lee, S. J. Myostatin mutation associated with gross muscle hypertrophy in a child N. Engl. J. Med. 2004, 350, 2682-2688
4. Patel, K.; Amthor, H. The function of myostatin and strategies of myostatin blockade-new hope for therapies aimed at promoting growth of skeletal muscle Neuromuscular Disord. 2005, 15, 117-126
5. McPherron, A. C.; Lee, S. J. Suppression of body fat accumulation in myostatin-deficient mice J. Clin. Invest. 2002, 109, 595-601
6. Lin, J.; Arnold, H. B.; Della-Fera, M. A.; Azain, M. J.; Hartzell, D. L.; Baile, C. A. Myostatin knockout in mice increases myogenesis and decreases adipogenesis Biochem. Biophys. Res. Commun. 2002, 291, 701-706
7. Tu, P.; Bhasin, S.; Hruz, P. W.; Herbst, K. L.; Castellani, L. W.; Hua, N.; Hamilton, J. A.; Guo, W. Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice Diabetes 2009, 58, 1739-1748
8. Wilkes, J. J.; Lloyd, D. J.; Gekakis, N. Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance Diabetes 2009, 58, 1133-1143
9. Guo, T.; Jou, W.; Chanturiya, T.; Portas, J.; Gavrilova, O.; McPherron, A. C. Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity PLoS One 2009, 4, e4937
10. Hamrick, M. W.; Pennington, C.; Webb, C. N.; Isales, C. M. Resistance to body fat gain in double-muscled mice fed a high-fat diet Int. J. Obes. 2006, 30, 868-870
11. Rodgers, B. D.; Garikipati, D. K. Clinical, agricultural, and evolutionary biology of myostatin: A comparative review Endocr. Rev. 2008, 29, 513-534
12. Joulia-Ekaza, D.; Cabello, G. Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects Exp. Cell Res. 2006, 312, 2401-2414
13. Matsakas, A.; Diel, P. The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis Int. J. Sports Med. 2005, 26, 83-89
14. Joulia-Ekaza, D.; Cabello, G. The myostatin gene: physiology and pharmacological relevance Curr. Opin. Pharmacol. 2007, 7, 310-315
15. Thies, R. S.; Chen, T.; Davies, M. V.; Tomkinson, K. N.; Pearson, A. A.; Shakey, Q. A.; Wolfman, N. M. GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding Growth Factors 2001, 18, 251-259
16. Lee, S. J. Genetic analysis of the role of proteolysis in the activation of latent myostatin PLoS One 2008, 3, e1628
17. Lee, S. J. Extracellular regulation of myostatin: a molecular rheostat for muscle mass Immunol., Endocr. Metab. Agents Med. Chem. 2010, 10, 183-194
18. Hill, J. J.; Davies, M. V.; Pearson, A. A.; Wang, J. H.; Hewick, R. M.; Wolfman, N. M.; Qiu, Y. The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum J. Biol. Chem. 2002, 277, 40735-40741
19. Hamrick, M. W.; Arounleut, P.; Kellum, E.; Cain, M.; Immel, D.; Liang, L. F. Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant musculoskeletal injury J. Trauma 2010, 69, 579-583
20. Arounleut, P.; Bialek, P.; Liang, L. F.; Upadhyay, S.; Fulzele, S.; Johnson, M.; Elsalanty, M.; Isales, C. M.; Hamrick, M. W. A myostatin inhibitor (propeptide-Fc) increases muscle mass and muscle fiber size in aged mice but does not increase bone density or bone strength Exp. Gerontol. 2013, 48, 898-904
21. Guo, W.; Wong, S.; Bhasin, S. AAV-mediated administration of myostatin pro-peptide mutant in adult Ldlr null mice reduces diet-induced hepatosteatosis and arteriosclerosis PLoS One 2013, 8, e71017
22. Springer, J.; Adams, V.; Anker, S. D. Myostatin: regulator of muscle wasting in heart failure and treatment target for cardiac cachexia Circulation 2010, 121, 354-356
23. Costelli, P.; Muscaritoli, M.; Bonetto, A.; Penna, F.; Reffo, P.; Bossola, M.; Bonelli, G.; Doglietto, G. B.; Baccino, F. M.; Fanelli, F. R. Muscle myostatin signalling is enhanced in experimental cancer cachexia Eur. J. Clin. Invest. 2008, 38, 531-538
24. Gonzalez-Cadavid, N. F.; Taylor, W. E.; Yarasheski, K.; Sinha-Hikim, I.; Ma, K.; Ezzat, S.; Shen, R.; Lalani, R.; Asa, S.; Mamita, M.; Nair, G.; Arver, S.; Bhasin, S. Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 14938-14943
25. Yarasheski, K. E.; Bhasin, S.; Sinha-Hikim, I.; Pak-Loduca, J.; Gonzalez-Cadavid, N. F. Serum myostatin-immunoreactive protein is increased in 60-92 year old women and men with muscle wasting J. Nutr., Health Aging 2002, 6, 343-348
26. Hittel, D. S.; Berggren, J. R.; Shearer, J.; Boyle, K.; Houmard, J. A. Increased secretion and expression of myostatin in skeletal muscle from extremely obese women Diabetes 2009, 58, 30-38
27. Palsgaard, J.; Brons, C.; Friedrichsen, M.; Dominguez, H.; Jensen, M.; Storgaard, H.; Spohr, C.; Torp-Pedersen, C.; Borup, R.; De, M. P.; Vaag, A. Gene expression in skeletal muscle biopsies from people with type 2 diabetes and relatives: differential regulation of insulin signaling pathways PloS One 2009, 4, e6575
28. Guo, J.; Tian, T.; Lu, D.; Xia, G.; Wang, H.; Dong, M. Alterations of maternal serum and placental follistatin-like 3 and myostatin in pre-eclampsia J. Obstet. Gynaecol. Res. 2012, 38, 988-996
29. Peiris, H. N.; Ponnampalam, A. P.; Mitchell, M. D.; Green, M. P. Sexual dimorphic expression of myostatin and follistatin like-3 in a rat trans-generational under-nutrition model Nutr. Metab. 2010, 7, 44
30. Rappsilber, J.; Ishihama, Y.; Mann, M. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics Anal. Chem. 2003, 75, 663-670
31. Wisniewski, J. R.; Zougman, A.; Mann, M. Combination of FASP and StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome J. Proteome Res. 2009, 8, 5674-5678
32. Wisniewski, J. R.; Zougman, A.; Nagaraj, N.; Mann, M. Universal sample preparation method for proteome analysis Nat. Methods 2009, 6, 359-362
33. Aebersold, R.; Burlingame, A. L.; Bradshaw, R. A. Western blots versus selected reaction monitoring assays: time to turn the tables? Mol. Cell. Proteomics 2013, 12, 2381-2382
34. Bantscheff, M.; Lemeer, S.; Savitski, M. M.; Kuster, B. Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present Anal. Bioanal. Chem. 2012, 404, 939-965
35. Karumanchi, S. A.; Maynard, S. E.; Stillman, I. E.; Epstein, F. H.; Sukhatme, V. P. Preeclampsia: a renal perspective Kidney Int. 2005, 67, 2101-2113
36. Hu, D.; Tian, T.; Guo, J.; Wang, H.; Chen, D.; Dong, M. Decreased maternal and placental concentrations of follistatin-like 3 in gestational diabetes Clin. Chim. Acta 2012, 413, 533-536
37. Brandt, C.; Nielsen, A. R.; Fischer, C. P.; Hansen, J.; Pedersen, B. K.; Plomgaard, P. Plasma and muscle myostatin in relation to type 2 diabetes PLoS One 2012, 7, e37236