메뉴 건너뛰기




Volumn 69, Issue 3, 2010, Pages 579-583

Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant musculoskeletal injury

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR ANTAGONIST; MYOSTATIN; RECOMBINANT MYOSTATIN PROPEPTIDE; UNCLASSIFIED DRUG; MSTN PROTEIN, MOUSE; RECOMBINANT PROTEIN;

EID: 77957599249     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181c451f4     Document Type: Article
Times cited : (66)

References (37)
  • 1
    • 1642513677 scopus 로고    scopus 로고
    • Developmental aspects of fracture healing and the use of pharmacological agents to alter healing
    • Gerstenfeld L, Einhorn T. Developmental aspects of fracture healing and the use of pharmacological agents to alter healing. J Musculoskelet Neuronal Interact. 2003;3:297-303. (Pubitemid 38111612)
    • (2003) Journal of Musculoskeletal Neuronal Interactions , vol.3 , Issue.4 , pp. 297-303
    • Gerstenfeld, L.C.1    Einhorn, T.A.2
  • 3
    • 0034038145 scopus 로고    scopus 로고
    • Effect of soft-tissue trauma on the early periosteal response of bone to injury
    • Landry P, Marino A, Sadasivan K, Albright J. Effect of soft-tissue trauma on the early periosteal response of bone to injury. J Trauma. 2000;48:479-483.
    • (2000) J. Trauma. , vol.48 , pp. 479-483
    • Landry, P.1    Marino, A.2    Sadasivan, K.3    Albright, J.4
  • 7
    • 0020074967 scopus 로고
    • Periosteal and metaplastic bone formation in mouse minced muscle regeneration
    • Zacks SI, Sheff MF. Periosteal and metaplastic bone formation in mouse minced muscle regeneration. Lab Invest. 1982;46:405-412.
    • (1982) Lab. Invest. , vol.46 , pp. 405-412
    • Zacks, S.I.1    Sheff, M.F.2
  • 8
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-ß superfamily member
    • McPherron AC, Lawler AM, Lee S-J. Regulation of skeletal muscle mass in mice by a new TGF-ß superfamily member. Nature. 1997;387:83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.-J.3
  • 9
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee SJ. Regulation of muscle mass by myostatin. Ann Rev Cell Dev Biol. 2004;20:61-86.
    • (2004) Ann. Rev. Cell. Dev. Biol. , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 10
    • 34249733201 scopus 로고    scopus 로고
    • A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs
    • Mosher DS, Quignon P, Bustamante CD, et al. A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet. 2007;3: e79.
    • (2007) PLoS Genet. , vol.3
    • Mosher, D.S.1    Quignon, P.2    Bustamante, C.D.3
  • 11
    • 2942735123 scopus 로고    scopus 로고
    • Myostatin mutation associated with gross muscle hypertrophy in a child
    • Schuelke M, Wagner K, Stolz L, et al. Myostatin mutation associated with gross muscle hypertrophy in a child. N Engl J Med. 2004;350:2682-2688.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2682-2688
    • Schuelke, M.1    Wagner, K.2    Stolz, L.3
  • 12
    • 34548492947 scopus 로고    scopus 로고
    • Relationships between transforming growth factor-beta1, myostatin, and decorin: Implications for skeletal muscle fibrosis
    • Zhu J, Li Y, Shen W, et al. Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis. J Biol Chem. 2007;282:25852-25863.
    • (2007) J. Biol. Chem. , vol.282 , pp. 25852-25863
    • Zhu, J.1    Li, Y.2    Shen, W.3
  • 13
    • 24344452642 scopus 로고    scopus 로고
    • Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice
    • McCroskery S, Thomas M, Platt L, et al. Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice. J Cell Sci. 2005;118(Part 15):3531-3541.
    • (2005) J. Cell. Sci. , vol.118 , Issue.15 PART , pp. 3531-3541
    • McCroskery, S.1    Thomas, M.2    Platt, L.3
  • 14
    • 34248584375 scopus 로고    scopus 로고
    • Loss of myostatin function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading
    • Hamrick MW, Shi X, Zhang W, et al. Loss of myostatin function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading. Bone. 2007;40:1544-1553.
    • (2007) Bone , vol.40 , pp. 1544-1553
    • Hamrick, M.W.1    Shi, X.2    Zhang, W.3
  • 15
    • 0141891154 scopus 로고    scopus 로고
    • Increased bone mineral density in the femora of GDF-8 knockout mice
    • Hamrick MW. Increased bone mineral density in the femora of GDF-8 knockout mice. Anat Rec A Discov Mol Cell Evol Biol. 2003;272:388-391.
    • (2003) Anat. Rec. A Discov. Mol. Cell. Evol. Biol. , vol.272 , pp. 388-391
    • Hamrick, M.W.1
  • 16
    • 0142241272 scopus 로고    scopus 로고
    • Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF8 (myostatin)
    • Hamrick MW, Pennington C, Byron C. Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF8 (myostatin). J Orthop Res. 2003;21:1025-1032.
    • (2003) J. Orthop. Res. , vol.21 , pp. 1025-1032
    • Hamrick, M.W.1    Pennington, C.2    Byron, C.3
  • 17
    • 36649003506 scopus 로고    scopus 로고
    • Association between myostatin gene polymorphisms and peak BMD variation in Chinese nuclear families
    • Zhang ZL, He JW, Qin YJ, et al. Association between myostatin gene polymorphisms and peak BMD variation in Chinese nuclear families. Osteoporosis Int. 2008;19:39-47.
    • (2008) Osteoporosis Int. , vol.19 , pp. 39-47
    • Zhang, Z.L.1    He, J.W.2    Qin, Y.J.3
  • 18
    • 34548702201 scopus 로고    scopus 로고
    • In vivo evaluation of changes in body composition of transgenic mice expressing the myostatin pro-domain using dual energy X-ray absorptiometry
    • Mitchell A, Wall R. In vivo evaluation of changes in body composition of transgenic mice expressing the myostatin pro-domain using dual energy X-ray absorptiometry. Growth Dev Aging. 2007;70:25-37.
    • (2007) Growth Dev. Aging , vol.70 , pp. 25-37
    • Mitchell, A.1    Wall, R.2
  • 19
    • 0036181393 scopus 로고    scopus 로고
    • Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing
    • Cho T, Gerstenfeld L, Einhorn T. Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res. 2002;17:513-520.
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 513-520
    • Cho, T.1    Gerstenfeld, L.2    Einhorn, T.3
  • 20
    • 0032078468 scopus 로고    scopus 로고
    • Immunohistochemical detection of activin A, follistatin, and activin receptors during fracture healing in the rat
    • Nagamine T, Imamura T, Ishidou Y, et al. Immunohistochemical detection of activin A, follistatin, and activin receptors during fracture healing in the rat. J Orthop Res. 1998;16:314-321.
    • (1998) J. Orthop. Res. , vol.16 , pp. 314-321
    • Nagamine, T.1    Imamura, T.2    Ishidou, Y.3
  • 21
    • 57449118268 scopus 로고    scopus 로고
    • Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume
    • Kellum E, Starr H, Arounleut P, et al. Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume. Bone. 2009;44:17-23.
    • (2009) Bone , vol.44 , pp. 17-23
    • Kellum, E.1    Starr, H.2    Arounleut, P.3
  • 22
    • 0034883063 scopus 로고    scopus 로고
    • GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding
    • Thies RS, Chen T, Davies MV, et al. GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding. Growth Factors. 2001;18:251-259.
    • (2001) Growth Factors , vol.18 , pp. 251-259
    • Thies, R.S.1    Chen, T.2    Davies, M.V.3
  • 23
    • 0037174939 scopus 로고    scopus 로고
    • The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum
    • Hill JJ, Davies MV, Pearson AA, et al. The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum. J Biol Chem. 2002;277:40735-40741.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40735-40741
    • Hill, J.J.1    Davies, M.V.2    Pearson, A.A.3
  • 25
    • 25844484021 scopus 로고    scopus 로고
    • Transgenic overexpression of myostatin propeptide prevents diet-induced obesity and insulin resistance
    • Zhao B, Wall R, Yang J. Transgenic overexpression of myostatin propeptide prevents diet-induced obesity and insulin resistance. Biochem Biophys Res Commun. 2005;337:248-255.
    • (2005) Biochem. Biophys. Res. Commun. , vol.337 , pp. 248-255
    • Zhao, B.1    Wall, R.2    Yang, J.3
  • 27
    • 57449097320 scopus 로고    scopus 로고
    • Mice treated with a myostatin/GDF-8 decoy receptor, ActRIIB-Fc, exhibit a tremendous increase in bone mass
    • Bialek P, Parkington J, Warner L, et al. Mice treated with a myostatin/GDF-8 decoy receptor, ActRIIB-Fc, exhibit a tremendous increase in bone mass. Bone. 2008;42: S46.
    • (2008) Bone , vol.42
    • Bialek, P.1    Parkington, J.2    Warner, L.3
  • 28
    • 0036895736 scopus 로고    scopus 로고
    • Loss of myostatin attenuates severity of muscular dystrophy in mdx mice
    • Wagner KR, McPherron AC, Winik N, Lee SJ. Loss of myostatin attenuates severity of muscular dystrophy in mdx mice. Ann Neurol. 2002;52:832-836.
    • (2002) Ann. Neurol. , vol.52 , pp. 832-836
    • Wagner, K.R.1    McPherron, A.C.2    Winik, N.3    Lee, S.J.4
  • 29
    • 44849140764 scopus 로고    scopus 로고
    • A phase I/II trial of MYO-029 in adult subjects with muscular dystrophy
    • Wagner KR, Fleckenstein JL, Amato AA, et al. A phase I/II trial of MYO-029 in adult subjects with muscular dystrophy. Ann Neurol. 2008;63:561-571.
    • (2008) Ann. Neurol. , vol.63 , pp. 561-571
    • Wagner, K.R.1    Fleckenstein, J.L.2    Amato, A.A.3
  • 30
    • 27544453428 scopus 로고    scopus 로고
    • Muscle regeneration through myostatin inhibition
    • Wagner KR. Muscle regeneration through myostatin inhibition. Curr Opin Rheumatol. 2005;17:720-724.
    • (2005) Curr. Opin. Rheumatol. , vol.17 , pp. 720-724
    • Wagner, K.R.1
  • 31
    • 44149119111 scopus 로고    scopus 로고
    • Inhibiting myostatin with follistatin improves the success of myoblast transplantation in dystrophic mice
    • Benabdallah B, Bouchentouf M, Rousseau J, et al. Inhibiting myostatin with follistatin improves the success of myoblast transplantation in dystrophic mice. Cell Transplant. 2008;17:337-350.
    • (2008) Cell. Transplant , vol.17 , pp. 337-350
    • Benabdallah, B.1    Bouchentouf, M.2    Rousseau, J.3
  • 32
    • 34548752062 scopus 로고    scopus 로고
    • Combat orthopaedics: A view from the trenches
    • Covey D. Combat orthopaedics: a view from the trenches. J Am Acad Orthop Surg. 2006;14: S10-S17.
    • (2006) J. Am. Acad. Orthop. Surg. , vol.14
    • Covey, D.1
  • 33
    • 34247156602 scopus 로고    scopus 로고
    • Characterization of open extremity wounds in operation Iraqi freedom and operation enduring freedom
    • Owens B, Kragh JF Jr, Macaitis J, Svoboda SJ, Wenke JC. Characterization of open extremity wounds in Operation Iraqi Freedom and Operation Enduring Freedom. J Orthop Trauma. 2007;21:254-257.
    • (2007) J. Orthop. Trauma. , vol.21 , pp. 254-257
    • Owens, B.1    Kragh Jr., J.F.2    Macaitis, J.3    Svoboda, S.J.4    Wenke, J.C.5
  • 34
    • 0036635247 scopus 로고    scopus 로고
    • Blast and fragment injuries of the musculoskeletal system
    • Covey DC. Blast and fragment injuries of the musculoskeletal system. J Bone Joint Surg Am. 2002;84-A:1221-1234.
    • (2002) J. Bone Joint Surg. Am. , vol.84 A , pp. 1221-1234
    • Covey, D.C.1
  • 35
    • 39049086760 scopus 로고    scopus 로고
    • Regenerative medicine for the musculoskeletal system based on muscle-derived stem cells
    • Gates CB, Karthikeyan T, Fu F, Huard J. Regenerative medicine for the musculoskeletal system based on muscle-derived stem cells. J Am Acad Orthop Surg. 2008;16:68-76.
    • (2008) J. Am. Acad. Orthop. Surg. , vol.16 , pp. 68-76
    • Gates, C.B.1    Karthikeyan, T.2    Fu, F.3    Huard, J.4
  • 36
    • 58849134888 scopus 로고    scopus 로고
    • Reproducibility of an animal model simulating complex combat-related injury in a multiple-institution format
    • Cho S, Holcomb J, Tieu B, et al. Reproducibility of an animal model simulating complex combat-related injury in a multiple-institution format. Shock. 2009;31:87-96.
    • (2009) Shock , vol.31 , pp. 87-96
    • Cho, S.1    Holcomb, J.2    Tieu, B.3
  • 37
    • 60549116904 scopus 로고    scopus 로고
    • Humoral factors enhance fracture-healing and callus formation in patients with traumatic brain injury
    • Cadosch D, Gautschi O, Thyer M, et al. Humoral factors enhance fracture-healing and callus formation in patients with traumatic brain injury. J Bone Joint Surg Am. 2009;91:282-288.
    • (2009) J. Bone Joint Surg. Am. , vol.91 , pp. 282-288
    • Cadosch, D.1    Gautschi, O.2    Thyer, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.